Endoplasmic Reticulum Stress and Disease

Endoplasmic Reticulum Stress and Disease is a research topic within Cell Biology. Science Explorer counts 34k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the molecular mechanisms, regulation, and consequences of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR). It explores the role of ER stress in various diseases such as diabetes, cancer, neurodegenerative diseases, and liver disease, highlighting its impact on cell fate decisions, protein folding, oxidative stress, and apoptosis. The cluster also delves into the involvement of UPR pathways, chaperones, and the interplay between ER stress and inflammation.

• Endoplasmic Reticulum
• Stress
• Unfolded Protein Response
• ER Stress
• Cell Death
• Protein Folding
• UPR Pathways
• Oxidative Stress
• Apoptosis
• Chaperones