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Topic · Cell Biology

Hippo pathway signaling and YAP/TAZ

Hippo pathway signaling and YAP/TAZ is a research topic within Cell Biology. Science Explorer counts 14k research works in it since 1952. 28.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the role of the Hippo signaling pathway, particularly the involvement of YAP/TAZ, in mechanotransduction, cell proliferation, tissue growth control, organ size control, and its implications in cancer and stem cell regulation.

  • Hippo Pathway
  • YAP/TAZ
  • mechanotransduction
  • cell proliferation
  • tissue growth control
  • organ size control
  • cancer
  • regulation
  • mechanobiology
  • stem cells
Research works
14k
fractional, since 1952
In the world top 10%
4k
per year above
Top-10% rate
28.9%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+38%
the tick is no change

Which countries lead Hippo pathway signaling and YAP/TAZ research?

By volume, China and the United States publish the most (1.2k and 638 works in 2022–2025).

By volume, 2022–2025

  1. 1 China 1.2k works
  2. 2 United States 638 works
  3. 3 Japan 127 works
  4. 4 South Korea 95 works
  5. 5 Germany 89 works
  6. 6 United Kingdom 87 works
  7. 7 France 80 works
  8. 8 Canada 69 works
  9. 9 India 63 works
  10. 10 Italy 51 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 48.0%United States: 25.5%Japan: 5.1%South Korea: 3.8%6 others listed: 17.6%48%largest
China1,201 · 48.0%United States638 · 25.5%Japan127 · 5.1%South Korea95 · 3.8%6 others listed440 · 17.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Hippo pathway signaling and YAP/TAZ research?

By volume in 2022–2025, Sun Yat-sen University publishes the most Hippo pathway signaling and YAP/TAZ research, followed by Sichuan University and Shanghai Jiao Tong University.

Who are the leading researchers in Hippo pathway signaling and YAP/TAZ?

The most-cited researchers publishing on Hippo pathway signaling and YAP/TAZ include Anil K. Sood.

  1. 1 Anil K. Sood United States 2.6k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Hippo pathway signaling and YAP/TAZ research done?

The largest centres of Hippo pathway signaling and YAP/TAZ research in 2022–2025 are Shanghai (China), Beijing (China), Guangzhou (China) and Hangzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Houston and Nanchang.

Largest cities, 2022–2025

  1. 1 Shanghai China 121 works
  2. 2 Beijing China 101 works
  3. 3 Guangzhou China 83 works
  4. 4 Hangzhou China 57 works
  5. 5 Seoul South Korea 52 works
  6. 6 Wuhan China 47 works
  7. 7 Xi'an China 43 works
  8. 8 Paris France 43 works
  9. 9 Changsha China 42 works
  10. 10 Chengdu China 42 works

Where it is the local speciality

  1. HoustonUS · 32.7 works4.8×
  2. NanchangCN · 23.4 works4.7×
← less than its size predictsmore →

Location quotient: how much more of its research is in Hippo pathway signaling and YAP/TAZ than the world average.

See Hippo pathway signaling and YAP/TAZ on the map

Where is the best place to study Hippo pathway signaling and YAP/TAZ?

Among universities, judged by research, Southern Medical University, China Medical University and Sun Yat-sen University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 34.62%fractional works in this node (log) →share in the world top 10% →Southern Medical University: 9, 43.6%China Medical University: 11, 40.3%Sun Yat-sen University: 21, 34.4%Nanjing Medical University: 13, 21.3%Soochow University: 11, 40.5%Huazhong University of Science and Technology: 11, 46.7%Chinese Academy of Medical Sciences & Peking Union Medical College: 14, 42.3%Tianjin Medical University: 8, 28.1%Chongqing Medical University: 10, 23.9%Sichuan University: 18, 25.1%Southern Medical Uni…China Medical Univer…Sun Yat-sen UniversityNanjing Medical Univ…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Southern Medical UniversityChina 67.643.6%9.1×9 +196.8%
2 China Medical UniversityChina 62.640.3%12.0×11 +89.1%
3 Sun Yat-sen UniversityChina 59.734.4%4.8×21 +113.4%
4 Nanjing Medical UniversityChina 56.721.3%9.4×13 +627.4%
5 Soochow UniversityChina 56.440.5%4.9×11 +410.4%
6 Huazhong University of Science and TechnologyChina 55.046.7%2.5×11 +293.3%
7 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 54.842.3%5.3×14 +49.0%
8 Tianjin Medical UniversityChina 54.728.1%14.9×8 +262.2%
9 Chongqing Medical UniversityChina 54.123.9%10.8×10 +413.8%
10 Sichuan UniversityChina 49.825.1%3.8×18 +213.7%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Hippo pathway signaling and YAP/TAZ research growing?

Output in 2018–2022 was 38% higher than in 2013–2017, peaking in 2020. The fastest-growing topics are Hippo pathway signaling and YAP/TAZ.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.