Most cited papers in Alkaloids: synthesis and pharmacology
What are the most cited papers in Alkaloids: synthesis and pharmacology?
The most cited paper in Alkaloids: synthesis and pharmacology is "Proline-Catalyzed Direct Asymmetric Aldol Reactions" (Benjamin List, Richard Alan Lerner, Carlos F. Barbas, 2000), with 2,868 citations. Next come "Qinghaosu (Artemisinin): an Antimalarial Drug from China" (2,188) and "New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels−Alder Reaction" (1,690).
Showing 50 of 100 papers. Every paper with more than 384 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Proline-Catalyzed Direct Asymmetric Aldol Reactions Benjamin List, Richard Alan Lerner, Carlos F. Barbas · Journal of the American Chemical Society | 26 Feb 2000 | 2,868 |
| 2 | Qinghaosu (Artemisinin): an Antimalarial Drug from China Daniel L. Klayman · Science | 31 May 1985 | 2,188 |
| 3 | New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels−Alder Reaction Kateri A. Ahrendt, Christopher J. Borths, David W. C. MacMillan · Journal of the American Chemical Society | 15 Apr 2000 | 1,690 |
| 4 | Aerobic Copper-Catalyzed Organic Reactions Scott E. Allen, Ryan R. Walvoord, Rosaura Padilla‐Salinas et al. · Chemical Reviews | 20 Jun 2013 | 1,623 |
| 5 | Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole Alkaloids Christiane Marti, Erick M. Carreira · European Journal of Organic Chemistry | Jun 2003 | 1,454 |
| 6 | Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products Gerhard Bringmann, Tanja Gulder, Tobias A. M. Gulder et al. · Chemical Reviews | 12 Oct 2010 | 1,442 |
| 7 | Characterization of ameboid microglia isolated from developing mammalian brain Dana Giulian, T J Baker · Journal of Neuroscience | Aug 1986 | 1,329 |
| 8 | Natural Deep Eutectic Solvents: Properties, Applications, and Perspectives Yang Liu, J. Brent Friesen, James B. McAlpine et al. · Journal of Natural Products | 7 Mar 2018 | 1,296 |
| 9 | Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids Arndt W. Schmidt, Kethiri R. Reddy, Hans‐Joachim Knölker · Chemical Reviews | 5 Apr 2012 | 1,244 |
| 10 | Green, Catalytic Oxidation of Alcohols in Water Gerd‐Jan ten Brink, Isabel W. C. E. Arends, Roger A. Sheldon · Science | 3 Mar 2000 | 1,157 |
| 11 | Chemistry and biology of monoterpene indole alkaloid biosynthesis Sarah Ellen O'Connor, Justin J. Maresh · Natural Product Reports | 2006 | 1,069 |
| 12 | Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations Chao Liu, Jiwen Yuan, Meng Gao et al. · Chemical Reviews | 11 Nov 2015 | 1,062 |
| 13 | St John's wort for depression—an overview and meta-analysis of randomised clinical trials Klaus Linde, Gilbert Ramı́rez, Cynthia D. Mulrow et al. · BMJ | 3 Aug 1996 | 995 |
| 14 | Pharmacological Treatment of Neuropsychiatric Symptoms of Dementia Kaycee M. Sink, Karen F. Holden, Kristine S. Yaffe · JAMA | Feb 2005 | 918 |
| 15 | Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling Marisa C. Kozlowski, Barbara J. Morgan, Elizabeth C. Linton · Chemical Society Reviews | 2009 | 907 |
| 16 | Alkaloids: An overview of their antibacterial, antibiotic-enhancing and antivirulence activities T.P. Tim Cushnie, Benjamart Cushnie, Andrew J. Lamb · International Journal of Antimicrobial Agents | 15 Jul 2014 | 904 |
| 17 | Assessing Atropisomer Axial Chirality in Drug Discovery and Development Steven R. LaPlante, Lee D. Fader, Keith R. Fandrick et al. · Journal of Medicinal Chemistry | 17 Aug 2011 | 864 |
| 18 | Highly Practical Copper(I)/TEMPO Catalyst System for Chemoselective Aerobic Oxidation of Primary Alcohols Jessica M. Hoover, Shannon S. Stahl · Journal of the American Chemical Society | 23 Aug 2011 | 800 |
| 19 | Neurotoxic Alkaloids: Saxitoxin and Its Analogs Maria Wiese, Paul Michael D'Agostino, Troco Kaan Mihali et al. · Marine Drugs | 20 Jul 2010 | 773 |
| 20 | A Versatile and Highly Selective Hypervalent Iodine (III)/2,2,6,6-Tetramethyl-1-piperidinyloxyl-Mediated Oxidation of Alcohols to Carbonyl Compounds Antonella De Mico, Roberto Margarita, Luca Parlanti et al. · The Journal of Organic Chemistry | Oct 1997 | 772 |
| 21 | Comparison of Risperidone and Placebo for Psychosis and Behavioral Disturbances Associated With Dementia Ira R. Katz, Dilip V. Jeste, Jacobo E Mintzer et al. · The Journal of Clinical Psychiatry | 15 Feb 1999 | 749 |
| 22 | Collective synthesis of natural products by means of organocascade catalysis Spencer B. Jones, Bryon L. Simmons, Anthony Mastracchio et al. · Nature | Jul 2011 | 737 |
| 23 | The Catharanthus Alkaloids:Pharmacognosy and Biotechnology Robert van der Heijden, Denise I. Jacobs, Wim Snoeijer et al. · Current Medicinal Chemistry | Mar 2004 | 733 |
| 24 | Codeine Intoxication Associated with Ultrarapid CYP2D6 Metabolism Yvan Gasche, Youssef Daali, Marc Fathi et al. · New England Journal of Medicine | 30 Dec 2004 | 703 |
| 25 | Antibacterial Natural Products in Medicinal Chemistry—Exodus or Revival? Franz von Nussbaum, Michael W Brands, Berthold Hinzen et al. · Angewandte Chemie International Edition | 31 Jul 2006 | 676 |
| 26 | The Characterization of High‐Fat Diet and Multiple Low‐Dose Streptozotocin Induced Type 2 Diabetes Rat Model Ming Zhang, Xiaoyan Lv, Jing Li et al. · Journal of Diabetes Research | 2008 | 673 |
| 27 | Recent applications of C–H functionalization in complex natural product synthesis Dylan J. Abrams, Philip A. Provencher, Erik J. Sorensen · Chemical Society Reviews | 2018 | 665 |
| 28 | Organocatalytic Asymmetric Synthesis of Indole-Based Chiral Heterocycles: Strategies, Reactions, and Outreach Yu‐Chen Zhang, Fei Jiang, Feng Shi · Accounts of Chemical Research | 10 Dec 2019 | 649 |
| 29 | Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine Mohsen Imanshahidi, Hossein Hosseinzadeh · Phytotherapy Research | 29 Jul 2008 | 641 |
| 30 | New horizons in the extraction of bioactive compounds using deep eutectic solvents: A review Mohamad Hamdi Zainal-Abidin, Maan Hayyan, Adeeb Hayyan et al. · Analytica Chimica Acta | 29 May 2017 | 636 |
| 31 | Enantioselective Organocatalytic Indole Alkylations. Design of a New and Highly Effective Chiral Amine for Iminium Catalysis Joel F. Austin, David W. C. MacMillan · Journal of the American Chemical Society | 26 Jan 2002 | 624 |
| 32 | Diastereoselective Allylation of Carbonyl Compounds and Imines: Application to the Synthesis of Natural Products Miguel Yus, Jose Carlos Gonzalez‐Gomez, Francisco Foubelo · Chemical Reviews | 29 Mar 2013 | 613 |
| 33 | Gelsemine: A Thought‐Provoking Target for Total Synthesis Hong Lin, Samuel J. Danishefsky · Angewandte Chemie International Edition | 3 Jan 2003 | 602 |
| 34 | Practical Aerobic Oxidations of Alcohols and Amines with Homogeneous Copper/TEMPO and Related Catalyst Systems Bradford L. Ryland, Shannon S. Stahl · Angewandte Chemie International Edition | 7 Jul 2014 | 596 |
| 35 | Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)*1 Andreas Johne · Clinical Pharmacology & Therapeutics | Oct 1999 | 592 |
| 36 | Ligand-Modulated Palladium-Catalyzed Aerobic Alcohol Oxidations Matthew S. Sigman, David R. Jensen · Accounts of Chemical Research | 20 Jan 2006 | 578 |
| 37 | Treatment of Type 2 Diabetes and Dyslipidemia with the Natural Plant Alkaloid Berberine Yifei Zhang, Xiaoying Li, Dajin Zou et al. · The Journal of Clinical Endocrinology & Metabolism | 8 Apr 2008 | 573 |
| 38 | Samarium(II)-Iodide-Mediated Cyclizations in Natural Product Synthesis David J. Edmonds, Derek Johnston, David J. Procter · Chemical Reviews | 27 May 2004 | 571 |
| 39 | Galanthamine from snowdrop—the development of a modern drug against Alzheimer’s disease from local Caucasian knowledge Michael Heinrich, Hooi Lee Teoh · Journal of Ethnopharmacology | 13 Apr 2004 | 569 |
| 40 | The Vinylogous Aldol Reaction: A Valuable, Yet Understated Carbon−Carbon Bond-Forming Maneuver Giovanni Casiraghi, Franca Zanardi, Giovanni Appendino et al. · Chemical Reviews | 27 May 2000 | 564 |
| 41 | Organocatalytic Direct Asymmetric Aldol Reactions in Water. Nobuyuki Mase, Yusuke Nakai, Naoko Ohara et al. · ChemInform | 23 May 2006 | 558 |
| 42 | Berberine: Botanical Occurrence, Traditional Uses, Extraction Methods, and Relevance in Cardiovascular, Metabolic, Hepatic, and Renal Disorders Maria Adriana Neag, Andrei Mocan, Javier Echeverría et al. · Frontiers in Pharmacology | 21 Aug 2018 | 556 |
| 43 | Enantioselective Pictet−Spengler-Type Cyclizations of Hydroxylactams: H-Bond Donor Catalysis by Anion Binding Izzat T. Raheem, Parvinder S. Thiara, Emily A. Peterson et al. · Journal of the American Chemical Society | 17 Oct 2007 | 553 |
| 44 | Semipinacol Rearrangement in Natural Product Synthesis Zhenlei Song, Chun‐An Fan, Yong‐Qiang Tu · Chemical Reviews | 18 Aug 2011 | 544 |
| 45 | Simple indole alkaloids and those with a non-rearranged monoterpenoid unit Masanori Somei, Fumio Yamada · Natural Product Reports | 2005 | 542 |
| 46 | Current knowledge and pharmacological profile of berberine: An update Anil Kumar, Ekavali, Kanwaljit Chopra et al. · European Journal of Pharmacology | 16 Jun 2015 | 539 |
| 47 | Revealing Atropisomer Axial Chirality in Drug Discovery Steven R. LaPlante, Paul John Edwards, Lee D. Fader et al. · ChemMedChem | 5 Jan 2011 | 534 |
| 48 | Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I Nigel A. Turner, Jing-Ya Li, Alison K. Gosby et al. · Diabetes | 19 Feb 2008 | 532 |
| 49 | Comprehensive Evaluation of Deep Eutectic Solvents in Extraction of Bioactive Natural Products Li Duan, Li−Li Dou, Long Yuan Guo et al. · ACS Sustainable Chemistry & Engineering | 18 Feb 2016 | 524 |
| 50 | The metabolism of berberine and its contribution to the pharmacological effects Kun Wang, Xinchi Feng, Liwei Chai et al. · Drug Metabolism Reviews | 14 Mar 2017 | 516 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.