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Topic · Autoimmune and Inflammatory Disorders Research

Most cited papers in Autoimmune and Inflammatory Disorders Research

Autoimmune and Inflammatory Disorders Research

What are the most cited papers in Autoimmune and Inflammatory Disorders Research?

The most cited paper in Autoimmune and Inflammatory Disorders Research is "COVID-19: consider cytokine storm syndromes and immunosuppression" (Puja Mehta, Daniel Francis McAuley, Michael Brown et al., 2020), with 10,244 citations. Next come "Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death" (6,817) and "EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update" (5,808).

Showing 50 of 100 papers. Every paper with more than 963 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 COVID-19: consider cytokine storm syndromes and immunosuppression Puja Mehta, Daniel Francis McAuley, Michael Brown et al. · The Lancet Open access Mar 2020 10,244
2 Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature 16 Sep 2015 6,817
3 EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update Josef S Smolen et al. · Annals of the Rheumatic Diseases Open access 6 Mar 2017 5,808
4 HLH‐2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis Jan‐Inge Henter, AnnaCarin Horne, Maurizio Aricò et al. · Pediatric Blood & Cancer 25 Aug 2006 5,452
5 IL-6 in Inflammation, Immunity, and Disease Toshio Tanaka, Masashi Narazaki, Tadamitsu Kishimoto · Cold Spring Harbor Perspectives in Biology Open access 4 Sep 2014 5,134
6 Rheumatoid arthritis Josef S Smolen, Daniel Aletaha, Iain B. McInnes · The Lancet 3 May 2016 4,910
7 Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling Nobuhiko Kayagaki et al. · Nature 16 Sep 2015 3,790
8 Hematological Problems in Pediatric Intensive Care Shoshana Revel‐Vilk, Peter N. Cox, Nancy Robitaille et al. · Pediatric and adolescent medicine Book chapter 28 Nov 2013 3,516
9 Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores Xing Liu, Zhibin Zhang, Jianbin Ruan et al. · Nature Open access 5 Jul 2016 3,316
10 Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature 28 Apr 2017 3,284
11 Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death Jianjin Shi, Wenqing Gao, Feng Shao · Trends in Biochemical Sciences Review 5 Dec 2016 3,222
12 Rheumatoid arthritis David Lloyd Scott, Frederick Wolfe, Tom W. J. Huizinga · The Lancet Open access Sep 2010 3,039
13 Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis Peter E. Lipsky, Désirée M F M van der Heijde, E. William St. Clair et al. · New England Journal of Medicine Open access 30 Nov 2000 3,023
14 STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD Dan Turner, Amanda Ricciuto, Ayanna E. Lewis et al. · Gastroenterology Open access 20 Feb 2021 2,882
15 Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease Jeffrey C. Barrett et al. · Nature Genetics Open access 29 Jun 2008 2,644
16 The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis Peter K. Gregersen, Jack Silver, ROBERT J. WINCHESTER · Arthritis & Rheumatism Nov 1987 2,607
17 Anti-TNF Antibody Therapy in Rheumatoid Arthritis and the Risk of Serious Infections and Malignancies Tim Bongartz, Alex J. Sutton, Michael J. Sweeting et al. · JAMA 16 May 2006 2,486
18 Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial Ravinder Nath Maini, E. William St. Clair, Ferdinand C. Breedveld et al. · The Lancet Dec 1999 2,361
19 Interleukin-1 in the pathogenesis and treatment of inflammatory diseases Charles Anthony Dinarello · Blood Open access 8 Feb 2011 2,275
20 Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis Ernest Choy, Gabriel S. Panayi · New England Journal of Medicine 22 Mar 2001 2,268
21 The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. Daniel Fishman, Gary Faulds, Rachel C. Jeffery et al. · Journal of Clinical Investigation Open access Oct 1998 2,261
22 Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part I Charles G. Helmick, David T. Felson, Reva C. Lawrence et al. · Arthritis & Rheumatism 28 Dec 2007 2,084
23 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus Antonis Fanouriakis et al. · Annals of the Rheumatic Diseases Open access 29 Mar 2019 2,051
24 Cytokine release syndrome in severe COVID-19 John B. Moore, Carl H. June · Science 17 Apr 2020 2,048
25 Juvenile idiopathic arthritis Angelo Ravelli, Alberto Martini · The Lancet Mar 2007 2,032
26 Cytokines in Inflammatory Disease Shinwan Kany, Jan Tilmann Vollrath, Borna Relja · International Journal of Molecular Sciences Open access 28 Nov 2019 2,000
27 Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease Jane W. Newburger, Masato Takahashi, Michael A. Gerber et al. · Circulation Open access 25 Oct 2004 1,952
28 Fibroblast‐like synoviocytes: key effector cells in rheumatoid arthritis Beatrix Bartók, Gary S. Firestein · Immunological Reviews ReviewOpen access 23 Dec 2009 1,947
29 A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 Jochen Hampe et al. · Nature Genetics 31 Dec 2006 1,911
30 Preliminary criteria for classification of adult Still's disease. Masaya Yamaguchi, Akio Ohta, T Tsunematsu et al. · PubMed Mar 1992 1,803
31 Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies Qiang Guo, Yuxiang Wang, Dan Xu et al. · Bone Research Open access 25 Apr 2018 1,794
32 The PREMIER study: A multicenter, randomized, double‐blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment Ferdinand C. Breedveld, Michael H. Weisman, Arthur F. Kavanaugh et al. · Arthritis & Rheumatism 29 Dec 2005 1,794
33 Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases Charles Anthony Dinarello, Anna Simon, Jos W.M. van der Meer · Nature Reviews Drug Discovery ReviewOpen access Aug 2012 1,787
34 Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial Lars Klareskog, Désirée M F M van der Heijde, J Jäger et al. · The Lancet Feb 2004 1,778
35 Adalimumab, a fully human anti–tumor necrosis factor α monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: The ARMADA trial Michael E. Weinblatt, Edward Clark Keystone, Daniel E. Furst et al. · Arthritis & Rheumatism 2003 1,767
36 Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice David Kägi, Birgit Ledermann, Kurt Bürki et al. · Nature 5 May 1994 1,765
37 The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease Dennis McGonagle, Kassem Sharif, Anthony W O'Regan et al. · Autoimmunity Reviews Open access 3 Apr 2020 1,752
38 Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases Si Ming Man, Rajendra Karki, Thirumala‐Devi Kanneganti · Immunological Reviews ReviewOpen access 30 Apr 2017 1,722
39 The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease and Current TNF-α Inhibitors in Therapeutics Dan-in Jang, A-Hyeon Lee, Hye-Yoon Shin et al. · International Journal of Molecular Sciences Open access 8 Mar 2021 1,697
40 Rituximab for rheumatoid arthritis refractory to anti–tumor necrosis factor therapy: Results of a multicenter, randomized, double‐blind, placebo‐controlled, phase III trial evaluating primary efficacy and safety at twenty‐four weeks Stanley B. Cohen, Paul E. Emery, Maria Greenwald et al. · Arthritis & Rheumatism 31 Aug 2006 1,651
41 Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor ? monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis Ravinder Nath Maini, Ferdinand C. Breedveld, Joachim Robert Kalden et al. · Arthritis & Rheumatism Sep 1998 1,644
42 \nEULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Josef S Smolen et al. · Radboud Repository (Radboud University) 2010 1,632
43 The biology of innate lymphoid cells David Artis, Hergen Spits · Nature Open access 13 Jan 2015 1,631
44 Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice Mary K. Kennedy, Moira B. Glaccum, Sandra N. Brown et al. · The Journal of Experimental Medicine Open access 28 Feb 2000 1,624
45 Development and evaluation of a scale to measure perceived self‐efficacy in people with arthritis Kate R. Lorig, Robert L. Chastain, Elaine Ung et al. · Arthritis & Rheumatism 1989 1,608
46 2017 European League Against Rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups Ingrid E. Lundberg et al. · Annals of the Rheumatic Diseases Open access 27 Oct 2017 1,587
47 Development and Validation of the HScore, a Score for the Diagnosis of Reactive Hemophagocytic Syndrome Laurence Fardet, Lionel Galicier, Olivier Lambotte et al. · Arthritis & Rheumatology 29 Apr 2014 1,501
48 American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease‐modifying antirheumatic drugs in rheumatoid arthritis Kenneth G. Saag et al. · Arthritis Care & Research 30 May 2008 1,495
49 Adult haemophagocytic syndrome Manuel Ramos‐Casals, Pilar Brito‐Zerón, Armando López‐Guillermo et al. · The Lancet 27 Nov 2013 1,473
50 Gasdermins: Effectors of Pyroptosis Stephen Bela Kovacs, Edward A. Miao · Trends in Cell Biology ReviewOpen access 12 Jun 2017 1,456

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.