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Most cited papers in Bacterial Infections and Vaccines

What are the most cited papers in Bacterial Infections and Vaccines?

The most cited paper in Bacterial Infections and Vaccines is "Neutrophil Extracellular Traps Kill Bacteria" (Volker Brinkmann, Ulrike Reichard, Christian Goosmann et al., 2004), with 10,383 citations. Next come "Multilocus sequence typing: A portable approach to the identification of clones within populations of pathogenic microorganisms" (3,872) and "Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae : Implications for the microbial “pan-genome”" (2,773).

Showing 50 of 99 papers. Every paper with more than 686 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Neutrophil Extracellular Traps Kill Bacteria Volker Brinkmann, Ulrike Reichard, Christian Goosmann et al. · Science 4 Mar 2004 10,383
2 Multilocus sequence typing: A portable approach to the identification of clones within populations of pathogenic microorganisms Martin C. J. Maiden, Jane A. Bygraves, Edward J. Feil et al. · Proceedings of the National Academy of Sciences Open access 17 Mar 1998 3,872
3 Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae : Implications for the microbial “pan-genome” Hervé Tettelin et al. · Proceedings of the National Academy of Sciences Open access 19 Sep 2005 2,773
4 BIGSdb: Scalable analysis of bacterial genome variation at the population level Keith A. Jolley, Martin C. J. Maiden · BMC Bioinformatics Open access Dec 2010 2,494
5 Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates Katherine L. O'Flynn O'Brien, Lara J. Wolfson, James Watt et al. · The Lancet Sep 2009 2,455
6 Practice Guidelines for the Management of Bacterial Meningitis Allan R. Tunkel, Barry J. Hartman, Sheldon L. Kaplan et al. · Clinical Infectious Diseases Open access 15 Oct 2004 2,341
7 Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 Valery L. Feigin et al. · The Lancet Neurology Open access243 authors 18 Sep 2017 2,329
8 Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles Bence György, Tamás Géza Szabó, Mária Pásztói et al. · Cellular and Molecular Life Sciences Open access 10 May 2011 2,104
9 Streptococcus pneumoniae colonisation: the key to pneumococcal disease Debby Bogaert, Ronald de Groot, PWM Hermans · The Lancet Infectious Diseases 27 Feb 2004 1,989
10 Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions Carmen Schwechheimer, Meta J. Kuehn · Nature Reviews Microbiology ReviewOpen access 16 Sep 2015 1,985
11 Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 Jaimie D Steinmetz et al. · The Lancet Neurology Open access1,264 authors 14 Mar 2024 1,978
12 Prevention and Control of Meningococcal Disease: Recommendations of the Advisory Committee on Immunization Practices (ACIP) Amanda C. Cohn, Jessica R. MacNeil, Thomas Arkle Clark et al. · PEDIATRICS 29 Oct 2013 1,847
13 Classification, Functions, and Clinical Relevance of Extracellular Vesicles Edwin van der Pol, Anita N. Böing, Paul J Harrison et al. · Pharmacological Reviews Jul 2012 1,788
14 Antimicrobial reactive oxygen and nitrogen species: concepts and controversies Ferric C. Fang · Nature Reviews Microbiology Review Oct 2004 1,685
15 Clinical Features and Prognostic Factors in Adults with Bacterial Meningitis Diederik van de Beek, Jan de Gans, Lodewijk Spanjaard et al. · New England Journal of Medicine Open access 28 Oct 2004 1,661
16 Biological Functions and Biogenesis of Secreted Bacterial Outer Membrane Vesicles Adam Kulp, Meta J. Kuehn · Annual Review of Microbiology ReviewOpen access 9 Sep 2010 1,560
17 Efficacy of a Pneumococcal Conjugate Vaccine against Acute Otitis Media Juhani Eskola, Terhi M Kilpi, ARTO A. I. PALMU et al. · New England Journal of Medicine Open access 8 Feb 2001 1,463
18 Identification of Vaccine Candidates Against Serogroup B Meningococcus by Whole-Genome Sequencing Mariagrazia Pizza et al. · Science 10 Mar 2000 1,412
19 Complete Genome Sequence of a Virulent Isolate of Streptococcus pneumoniae Hervé Tettelin et al. · Science 20 Jul 2001 1,372
20 Acute Bacterial Meningitis in Adults -- A Review of 493 Episodes Marlene L. Durand, Stephen B. Calderwood, David Jay Weber et al. · New England Journal of Medicine 7 Jan 1993 1,369
21 Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi Lisa C. Brown, Julie M. Wolf, Rafael Prados‐Rosales et al. · Nature Reviews Microbiology ReviewOpen access Sep 2015 1,361
22 Types and origins of bacterial membrane vesicles Masanori Toyofuku, Nobuhiko Nomura, Leo Eberl · Nature Reviews Microbiology Review 5 Nov 2018 1,356
23 The State of Vaccine Confidence 2016: Global Insights Through a 67-Country Survey Heidi Jane Larson, Alexandre de Figueiredo, Xiahong Zhao et al. · EBioMedicine Open access 14 Sep 2016 1,307
24 HUMAN IMMUNITY TO THE MENINGOCOCCUS Irving Goldschneider, Emil C. Gotschlich, Malcolm S. Artenstein · The Journal of Experimental Medicine Open access Jun 1969 1,301
25 Bacterial Meningitis in the United States in 1995 Anne Schuchat, Katherine A. Robinson, Jay D. Wenger et al. · New England Journal of Medicine 2 Oct 1997 1,261
26 Dexamethasone in Adults with Bacterial Meningitis Jan de Gans, Diederik van de Beek · New England Journal of Medicine Open access 13 Nov 2002 1,212
27 Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future Magnus Unemo, William Maurice Shafer · Clinical Microbiology Reviews Open access 30 Jun 2014 1,209
28 Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000–15 Brian Wahl, Katherine L. O'Flynn O'Brien, Adena H. Greenbaum et al. · The Lancet Global Health Open access 13 Jun 2018 1,181
29 Meningococcal Disease Nancy E. Rosenstein, Bradley A. Perkins, David S. Stephens et al. · New England Journal of Medicine 3 May 2001 1,180
30 Streptococcus pneumoniae: transmission, colonization and invasion Jeffrey N. Weiser, Daniela Mulari Ferreira, James C. Paton · Nature Reviews Microbiology ReviewOpen access 29 Mar 2018 1,171
31 The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease Aras Kadioglu, Jeffrey N. Weiser, James C. Paton et al. · Nature Reviews Microbiology Review 14 Mar 2008 1,171
32 Molecular Pathogenesis, Epidemiology, and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and Other Bordetella Subspecies Seema Mattoo, James D. Cherry · Clinical Microbiology Reviews Open access Apr 2005 1,143
33 Strategies for addressing vaccine hesitancy – A systematic review Caitlin Jarrett, Rose Wilson, Maureen O’Leary et al. · Vaccine ReviewOpen access 18 Apr 2015 1,112
34 Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58 Hervé Tettelin et al. · Science 10 Mar 2000 1,105
35 ASSOCIATION BETWEEN TUMOUR NECROSIS FACTOR IN SERUM AND FATAL OUTCOME IN PATIENTS WITH MENINGOCOCCAL DISEASE Anders Waage, Alfred Ingvar Halstensen, Terje Espevik · The Lancet Feb 1987 1,102
36 Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis Michael R. Wilson et al. · New England Journal of Medicine Open access 12 Jun 2019 1,093
37 A multilocus sequence typing scheme for Streptococcus pneumoniae: identification of clones associated with serious invasive disease Mark C. Enright, Brian G. Spratt · Microbiology Nov 1998 1,086
38 2017 Infectious Diseases Society of America’s Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis* Allan R. Tunkel, Rodrigo Hasbun, Adarsh Bhimraj et al. · Clinical Infectious Diseases Open access 16 Dec 2016 1,076
39 Dexamethasone for the Treatment of Tuberculous Meningitis in Adolescents and Adults Guy Edward Thwaites et al. · New England Journal of Medicine 20 Oct 2004 1,074
40 Serotype replacement in disease after pneumococcal vaccination Daniel M. Weinberger, Richard Malley, Marc Lipsitch · The Lancet Open access 20 Apr 2011 1,056
41 Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica Julian Parkhill et al. · Nature Genetics 8 Aug 2003 1,052
42 Penetration of Drugs through the Blood-Cerebrospinal Fluid/Blood-Brain Barrier for Treatment of Central Nervous System Infections Roland Nau, Fritz Sörgel, Helmut Eiffert · Clinical Microbiology Reviews Open access Oct 2010 1,046
43 Immune modulation by bacterial outer membrane vesicles Maria Kaparakis‐Liaskos, Richard L. Ferrero · Nature reviews. Immunology Review 15 May 2015 1,041
44 A Trial of a 9-Valent Pneumococcal Conjugate Vaccine in Children with and Those without HIV Infection Keith P. Klugman, Shabir Ahmed Madhi, Robin E. Huebner et al. · New England Journal of Medicine Open access Oct 2003 1,018
45 Biosynthesis and Assembly of Capsular Polysaccharides in Escherichia coli Chris Whitfield · Annual Review of Biochemistry Review 7 Apr 2006 1,016
46 Epidemic meningitis, meningococcaemia, and Neisseria meningitidis David S. Stephens, Brian M Greenwood, Petter Brandtzaeg · The Lancet Jun 2007 989
47 Virulence and Immunomodulatory Roles of Bacterial Outer Membrane Vesicles Terri N. Ellis, Meta J. Kuehn · Microbiology and Molecular Biology Reviews ReviewOpen access Mar 2010 972
48 Bacterial outer membrane vesicles and the host–pathogen interaction Meta J. Kuehn, Nicole C. Kesty · Genes & Development Open access 15 Nov 2005 970
49 Bacterial Meningitis in the United States, 1998–2007 Michael C. Thigpen, Cynthia G. Whitney, Nancy E. Messonnier et al. · New England Journal of Medicine Open access 25 May 2011 963
50 Epidemiology, Diagnosis, and Antimicrobial Treatment of Acute Bacterial Meningitis Matthijs C. Brouwer, Allan R. Tunkel, Diederik van de Beek · Clinical Microbiology Reviews Open access Jul 2010 946

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.