Topic · Berberine and alkaloids research
Most cited papers in Berberine and alkaloids research
What are the most cited papers in Berberine and alkaloids research?
The most cited paper in Berberine and alkaloids research is "Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy" (Ta-Chung Yu, Fangfang Guo, Yanan Yu et al., 2017), with 2,275 citations. Next come "Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins" (1,394) and "Chelerythrine is a potent and specific inhibitor of protein kinase C" (1,210).
Showing 50 of 100 papers. Every paper with more than 344 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy Ta-Chung Yu, Fangfang Guo, Yanan Yu et al. · Cell | Jul 2017 | 2,275 |
| 2 | Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins Weijia Kong, Jing Wei, Parveen Abidi et al. · Nature Medicine | 7 Nov 2004 | 1,394 |
| 3 | Chelerythrine is a potent and specific inhibitor of protein kinase C Jean‐Marc Herbert, Jean‐Michel Augereau, J. Gleye et al. · Biochemical and Biophysical Research Communications | Nov 1990 | 1,210 |
| 4 | Chemistry and Biology of the Tetrahydroisoquinoline Antitumor Antibiotics Jack D. Scott, Robert M. Williams · Chemical Reviews | 18 Apr 2002 | 1,148 |
| 5 | Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice Amit S. Choudhari, Pallavi C. Mandave, Manasi Deshpande et al. · Frontiers in Pharmacology | 28 Jan 2020 | 1,087 |
| 6 | Chemistry and biology of monoterpene indole alkaloid biosynthesis Sarah Ellen O'Connor, Justin J. Maresh · Natural Product Reports | 2006 | 1,069 |
| 7 | Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States Yun Sok Lee, Woo S. Kim, Kang H. Kim et al. · Diabetes | 27 Jul 2006 | 1,060 |
| 8 | A specific method for the analysis of hydroxyproline in tissues and urine Darwin J. Prockop, Sidney Udenfriend · Analytical Biochemistry | Nov 1960 | 1,059 |
| 9 | Alkaloids: An overview of their antibacterial, antibiotic-enhancing and antivirulence activities T.P. Tim Cushnie, Benjamart Cushnie, Andrew J. Lamb · International Journal of Antimicrobial Agents | 15 Jul 2014 | 904 |
| 10 | Efficacy of berberine in patients with type 2 diabetes mellitus Jun Jie Yin, Huili Xing, Jianping Ye · Metabolism | 27 Apr 2008 | 793 |
| 11 | Natural compounds for cancer treatment and prevention Stefania Nobili, Donatella Lippi, Ewa J. Witort et al. · Pharmacological Research | 8 Feb 2009 | 781 |
| 12 | Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5′-methoxyhydnocarpin, a multidrug pump inhibitor Frank R. Stermitz, Peter H. Lorenz, Jeanne N. Tawara et al. · Proceedings of the National Academy of Sciences | 4 Feb 2000 | 761 |
| 13 | A Population-Based Study of Diabetes and Its Characteristics During the Fasting Month of Ramadan in 13 Countries Ibrahim Salti, Éric Bénard, B. Detournay et al. · Diabetes Care | Oct 2004 | 746 |
| 14 | The Catharanthus Alkaloids:Pharmacognosy and Biotechnology Robert van der Heijden, Denise I. Jacobs, Wim Snoeijer et al. · Current Medicinal Chemistry | Mar 2004 | 733 |
| 15 | The Use of Silymarin in the Treatment of Liver Diseases Reinhard Saller, Remy F. Meier, Reto Brignoli · Drugs | 2001 | 724 |
| 16 | Alkaloid Biosynthesis: Metabolism and Trafficking Jörg Ziegler, Peter J. Facchini · Annual Review of Plant Biology | 5 Feb 2008 | 700 |
| 17 | The anti-inflammatory potential of berberine in vitro and in vivo Chi-Li Kuo, Chin‐Wen Chi, Tsung‐Yun Liu · Cancer Letters | 29 Oct 2003 | 692 |
| 18 | Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history Sara Anna Bonini, Marika Premoli, Simone Tambaro et al. · Journal of Ethnopharmacology | 8 Sep 2018 | 681 |
| 19 | β ‐caryophyllene and β ‐caryophyllene oxide—natural compounds of anticancer and analgesic properties Klaudyna Fidyt, Anna Fiedorowicz, Leon Strządała et al. · Cancer Medicine | 30 Sep 2016 | 673 |
| 20 | The Characterization of High‐Fat Diet and Multiple Low‐Dose Streptozotocin Induced Type 2 Diabetes Rat Model Ming Zhang, Xiaoyan Lv, Jing Li et al. · Journal of Diabetes Research | 2008 | 673 |
| 21 | Gut microbiome interactions with drug metabolism, efficacy, and toxicity Ian D. Wilson, Jeremy Kirk Nicholson · Translational research | 14 Aug 2016 | 661 |
| 22 | Structural Changes of Gut Microbiota during Berberine-Mediated Prevention of Obesity and Insulin Resistance in High-Fat Diet-Fed Rats Xu Zhang, Yufeng Zhao, Menghui H. Zhang et al. · PLoS ONE | 3 Aug 2012 | 659 |
| 23 | Acute heart transplant rejection due to Saint John's wort Frank T. Ruschitzka, Peter J. Meier, Marko Ivan Turina et al. · The Lancet | Feb 2000 | 653 |
| 24 | Caspases: pharmacological manipulation of cell death Inna N. Lavrik · Journal of Clinical Investigation | Oct 2005 | 648 |
| 25 | Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats Xu Zhang, Yufeng Zhao, Jia Yin Xu et al. · Scientific Reports | 23 Sep 2015 | 642 |
| 26 | An overview on ethnobotanico-pharmacological studies carried out in Morocco, from 1991 to 2015: Systematic review (part 1) Jamila Fakchich, Mostafa Elachouri · Journal of Ethnopharmacology | Aug 2020 | 641 |
| 27 | Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine Mohsen Imanshahidi, Hossein Hosseinzadeh · Phytotherapy Research | 29 Jul 2008 | 641 |
| 28 | A LKALOID B IOSYNTHESIS IN P LANTS : Biochemistry, Cell Biology, Molecular Regulation, and Metabolic Engineering Applications Peter J. Facchini · Annual Review of Plant Physiology and Plant Molecular Biology | Jun 2001 | 620 |
| 29 | Milk thistle in liver diseases: past, present, future Ludovico Abenavoli, Raffaele Capasso, Nataša Milić et al. · Phytotherapy Research | 7 Jun 2010 | 600 |
| 30 | Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids Berrın Özçelık, Murat Kartal, İlkay Erdoğan Orhan · Pharmaceutical Biology | 11 Mar 2011 | 588 |
| 31 | Treatment of Type 2 Diabetes and Dyslipidemia with the Natural Plant Alkaloid Berberine Yifei Zhang, Xiaoying Li, Dajin Zou et al. · The Journal of Clinical Endocrinology & Metabolism | 8 Apr 2008 | 573 |
| 32 | Berberine: Botanical Occurrence, Traditional Uses, Extraction Methods, and Relevance in Cardiovascular, Metabolic, Hepatic, and Renal Disorders Maria Adriana Neag, Andrei Mocan, Javier Echeverría et al. · Frontiers in Pharmacology | 21 Aug 2018 | 556 |
| 33 | Current knowledge and pharmacological profile of berberine: An update Anil Kumar, Ekavali, Kanwaljit Chopra et al. · European Journal of Pharmacology | 16 Jun 2015 | 539 |
| 34 | Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I Nigel A. Turner, Jing-Ya Li, Alison K. Gosby et al. · Diabetes | 19 Feb 2008 | 532 |
| 35 | The applications of Vitamin E TPGS in drug delivery Yuanyuan Guo, Jun Luo, Songwei Tan et al. · European Journal of Pharmaceutical Sciences | 26 Feb 2013 | 526 |
| 36 | Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine. Suresh Chandra Pradhan, Chandrashekaran Girish · PubMed | Nov 2006 | 518 |
| 37 | The metabolism of berberine and its contribution to the pharmacological effects Kun Wang, Xinchi Feng, Liwei Chai et al. · Drug Metabolism Reviews | 14 Mar 2017 | 516 |
| 38 | Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials Maija Dambrova, Marina Makrecka‐Kuka, Janis Kuka et al. · Pharmacological Reviews | 16 Jun 2022 | 515 |
| 39 | Biological properties and clinical applications of berberine Danyang Song, Jianyu Hao, Daiming Fan · Frontiers of Medicine | 25 Apr 2020 | 498 |
| 40 | Diversity in Chemical Structures and Biological Properties of Plant Alkaloids Sweta Bhambhani, Kirtikumar Ramesh Kondhare, Ashok Prabhakar Giri · Molecules | 3 Jun 2021 | 492 |
| 41 | Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years Alessandro Federico, Marcello Dallio, C. Loguercio · Molecules | 24 Jan 2017 | 491 |
| 42 | Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations Jun Tang, Yibin Feng, Sai‐Wah Tsao et al. · Journal of Ethnopharmacology | 16 Aug 2009 | 490 |
| 43 | Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine Praveen Dhyani, Cristina Quispe, Eshita Sharma et al. · Cancer Cell International | 2 Jun 2022 | 479 |
| 44 | Milk thistle ( Silybum marianum ): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases Ludovico Abenavoli, Angelo Antonio Izzo, Nataša Milić et al. · Phytotherapy Research | 6 Aug 2018 | 475 |
| 45 | Berberine: New perspectives for old remedies Micol Tillhon, Luis Miguel Guamán Ortiz, Paolo Lombardi et al. · Biochemical Pharmacology | 25 Jul 2012 | 475 |
| 46 | Pharmacogenetics, Pharmacogenomics, and Individualized Medicine Qiang Ma, Anthony Y.H. Lu · Pharmacological Reviews | 26 Apr 2011 | 468 |
| 47 | Aconitum in Traditional Chinese Medicine—A valuable drug or an unpredictable risk? Judith Singhuber, Ming Zhu, Sonja Prinz et al. · Journal of Ethnopharmacology | 4 Aug 2009 | 468 |
| 48 | Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension Jiarong Lan, Yanyun Zhao, Feixia Dong et al. · Journal of Ethnopharmacology | 10 Dec 2014 | 464 |
| 49 | Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics Xiaojun Feng, Antoni Sureda, Samineh Jafari et al. · Theranostics | 2019 | 461 |
| 50 | Berberine suppresses proinflammatory responses through AMPK activation in macrophages Hyun Woo Jeong, Kuan Chi Hsu, Joo-Won Lee et al. · American Journal of Physiology-Endocrinology and Metabolism | 11 Feb 2009 | 449 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.