Topic · Bioactive natural compounds
Most cited papers in Bioactive natural compounds
What are the most cited papers in Bioactive natural compounds?
The most cited paper in Bioactive natural compounds is "Antimicrobial activity of flavonoids" (T.P. Tim Cushnie, Andrew J. Lamb, 2005), with 4,427 citations. Next come "Advances in flavonoid research since 1992" (3,961) and "Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity" (2,145).
Showing 50 of 100 papers. Every paper with more than 392 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Antimicrobial activity of flavonoids T.P. Tim Cushnie, Andrew J. Lamb · International Journal of Antimicrobial Agents | 20 Oct 2005 | 4,427 |
| 2 | Advances in flavonoid research since 1992 Jeffrey B. Harborne, Christine A. Williams · Phytochemistry | Nov 2000 | 3,961 |
| 3 | Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity Nan Shen, Tongfei A. Wang, Quan Gan et al. · Food Chemistry | 23 Feb 2022 | 2,145 |
| 4 | Transcriptional control of flavonoid biosynthesis by MYB–bHLH–WDR complexes Weijie Xu, Christian Dubos, Loı̈c Lepiniec · Trends in Plant Science | 8 Jan 2015 | 2,090 |
| 5 | Stability of curcumin in buffer solutions and characterization of its degradation products Ying‐Jan Wang, Min‐Hsiung Pan, Ann‐Lii Cheng et al. · Journal of Pharmaceutical and Biomedical Analysis | Aug 1997 | 1,707 |
| 6 | Important Flavonoids and Their Role as a Therapeutic Agent Asad Ullah, Sidra Munir, Syed Lal Badshah et al. · Molecules | 10 Nov 2020 | 1,691 |
| 7 | Multiple biological activities of curcumin: A short review Radha K. Maheshwari, Anoop K. Singh, Jaya P. Gaddipati et al. · Life Sciences | 19 Jan 2006 | 1,670 |
| 8 | The Flavonoids: Advances in Research. P. Mick Richardson, Jeffrey B. Harborne, T. J. Mabry · Brittonia | 1984 | 1,430 |
| 9 | Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Bharat Bhushan Aggarwal, Anjana Bhardwaj, Rishi S. Aggarwal et al. · PubMed | 10 Dec 2004 | 1,391 |
| 10 | Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway Imène Hichri, François Barrieu, Jochen Bogs et al. · Journal of Experimental Botany | 28 Jan 2011 | 1,339 |
| 11 | Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature Preetha Anand, Sherin G. Thomas, Ajaikumar Bahulayan Kunnumakkara et al. · Biochemical Pharmacology | 20 Aug 2008 | 1,208 |
| 12 | The Flavonoid Biosynthesis Network in Plants Weixin Liu, Yi Feng, Suhang Yu et al. · International Journal of Molecular Sciences | 26 Nov 2021 | 1,030 |
| 13 | Anti-inflammatory Plant Flavonoids and Cellular Action Mechanisms Hyun Pyo Kim, Kun Ho Son, Hyeun Wook Chang et al. · Journal of Pharmacological Sciences | 2004 | 1,017 |
| 14 | A cross-cultural analysis of Jammu, Kashmir and Ladakh (India) medicinal plant use Sumeet Gairola, Jyotsana Sharma, Yashbir Singh Bedi · Journal of Ethnopharmacology | 18 Jun 2014 | 1,001 |
| 15 | Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus Wangjun Li, Huabin Zheng, Jacques Bukuru et al. · Journal of Ethnopharmacology | 17 Mar 2004 | 968 |
| 16 | Biotransformation of Curcumin Through Reduction and Glucuronidation in Mice Min‐Hsiung Pan, Tsang‐Miao Huang, Jen‐Kun Lin · Drug Metabolism and Disposition | Apr 1999 | 950 |
| 17 | Antioxidant and Anti-Inflammatory Properties of the Citrus Flavonoids Hesperidin and Hesperetin: An Updated Review of their Molecular Mechanisms and Experimental Models Hamideh Parhiz, Ali Roohbakhsh, Fatemeh Soltani et al. · Phytotherapy Research | 13 Nov 2014 | 918 |
| 18 | IKK/NF- B signaling: balancing life and death - a new approach to cancer therapy Jun‐Li Luo · Journal of Clinical Investigation | Oct 2005 | 883 |
| 19 | Resveratrol Suppresses TNF-Induced Activation of Nuclear Transcription Factors NF-κB, Activator Protein-1, and Apoptosis: Potential Role of Reactive Oxygen Intermediates and Lipid Peroxidation Sunil K. Manna, Asok Mukhopadhyay, Bharat Bhushan Aggarwal · The Journal of Immunology | Jun 2000 | 877 |
| 20 | Uses and Properties ofCitrusFlavonoids O. Benavente-García, Julián Castillo, Francisco R. Marín et al. · Journal of Agricultural and Food Chemistry | Dec 1997 | 868 |
| 21 | Chemistry and pharmacology of the citrus bioflavonoid hesperidin Alka B. Garg, Sanjay Garg, Lourens J. D. Zaneveld et al. · Phytotherapy Research | 23 Oct 2001 | 859 |
| 22 | Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals Subash C. Gupta, Ji Hye Kim, Sahdeo Prasad et al. · Cancer and Metastasis Reviews | 24 Aug 2010 | 806 |
| 23 | Flavonoids and Their Anti-Diabetic Effects: Cellular Mechanisms and Effects to Improve Blood Sugar Levels Raghad Khalid AL-Ishaq, Mariam Abotaleb, Peter Kubatka et al. · Biomolecules | Sep 2019 | 745 |
| 24 | Effect of Plant Flavonoids on Immune and Inflammatory Cell Function Elliott Middleton · Advances in experimental medicine and biology | 1998 | 740 |
| 25 | Resveratrol: A review of preclinical studies for human cancer prevention Mohammad Athar, Jung Ho Back, Xuemei Tang et al. · Toxicology and Applied Pharmacology | 5 Jan 2007 | 731 |
| 26 | Anti-Inflammatory Action and Mechanisms of Resveratrol Tiantian Meng, Dingfu Xiao, Arowolo Muhammed et al. · Molecules | 5 Jan 2021 | 706 |
| 27 | Resveratrol as an anti-inflammatory and anti-aging agent: Mechanisms and clinical implications Catalina Alarcón‐de‐la‐Lastra, Isabel Villegas · Molecular Nutrition & Food Research | 14 Apr 2005 | 705 |
| 28 | Comparative study on the antibacterial activity of phytochemical flavanones against methicillin-resistant Staphylococcus aureus Hironori Tsuchiya, Masaru Satô, Takashi Miyazaki et al. · Journal of Ethnopharmacology | 1996 | 699 |
| 29 | Determination of total flavonoid content by aluminum chloride assay: A critical evaluation Amjad M. Shraim, Talaat Abdel-Fattah Ahmed, Md Mizanur Rahman et al. · LWT | 18 Jun 2021 | 697 |
| 30 | Anti-inflammatory properties of plant flavonoids. Effects of rutin, quercetin and hesperidin on adjuvant arthritis in rat Teresita Guardia, Alejandra Ester Rotelli, Américo Juárez et al. · Il Farmaco | Aug 2001 | 697 |
| 31 | Anthocyanins and other flavonoids Christine A. Williams, Ren�e J. Grayer · Natural Product Reports | 2004 | 693 |
| 32 | A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone Sung‐Wuk Jang, Xia Liu, Manuel A Yepes et al. · Proceedings of the National Academy of Sciences | 25 Jan 2010 | 689 |
| 33 | Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses Stephen S. Leonard, Chang Xia, Bin-Hua Jiang et al. · Biochemical and Biophysical Research Communications | 12 Sep 2003 | 686 |
| 34 | Resveratrol, a Polyphenolic Phytoalexin Present in Red Wine, Enhances Expression and Activity of Endothelial Nitric Oxide Synthase Thomas Wallerath, Göran Deckert, Thomas A. Ternes et al. · Circulation | 23 Sep 2002 | 668 |
| 35 | Resveratrol as an anti-cancer agent: A review Abdur Rauf, Muhammad Imran, Masood Sadiq Butt et al. · Critical Reviews in Food Science and Nutrition | 21 Dec 2016 | 666 |
| 36 | Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine Dengyu Yang, Tiancheng Wang, Miao Long et al. · Oxidative Medicine and Cellular Longevity | 30 Dec 2020 | 647 |
| 37 | Clinical Pharmacology of Resveratrol and Its Metabolites in Colorectal Cancer Patients Ketan R. Patel, Victoria A. Brown, Donald J. L. Jones et al. · Cancer Research | 14 Sep 2010 | 624 |
| 38 | Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats Izet M. Kapetanović, Miguel Muzzio, Zhihua Huang et al. · Cancer Chemotherapy and Pharmacology | 29 Nov 2010 | 614 |
| 39 | Chemopreventive Agent Resveratrol, a Natural Product Derived From Grapes, Triggers CD95 Signaling-Dependent Apoptosis in Human Tumor Cells Marie‐Véronique Clement, Jayshreekumari L. Hirpara, Sanaul-Haq Chawdhury et al. · Blood | Aug 1998 | 606 |
| 40 | Flavonoids as superoxide scavengers and antioxidants Chen Yuting, Rongliang Zheng, Zhong‐Jian Jia et al. · Free Radical Biology and Medicine | 1990 | 594 |
| 41 | A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes Amina Mukhtar Dirir, Mariane Daou, Ahmed F. Yousef et al. · Phytochemistry Reviews | 16 Aug 2021 | 584 |
| 42 | Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells Yanyan Li, Tao Zhang, Hasan Körkaya et al. · Clinical Cancer Research | 14 Apr 2010 | 569 |
| 43 | Biological Properties of Citrus Flavonoids Pertaining to Cancer and Inflammation John A. Manthey, Najla Guthrie, Karel Grohmann · Current Medicinal Chemistry | Feb 2001 | 568 |
| 44 | The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cells María Victoria García‐Mediavilla, Irene Crespo, Pilar S. Collado et al. · European Journal of Pharmacology | 16 Nov 2006 | 562 |
| 45 | Resveratrol: A multitargeted agent for age-associated chronic diseases Kuzhuvelil B. Harikumar, Bharat Bhushan Aggarwal · Cell Cycle | 15 Apr 2008 | 552 |
| 46 | Controlled cell death, plant survival and development Eric Lam · Nature Reviews Molecular Cell Biology | Apr 2004 | 551 |
| 47 | Effects of naturally occurring flavonoids on nitric oxide production in the macrophage cell line RAW 264.7 and their structure–activity relationships Hee Kee Kim, Hee Kee Kim, Bong Sun Cheon et al. · Biochemical Pharmacology | Sep 1999 | 544 |
| 48 | Recent advances in understanding the anti-diabetic actions of dietary flavonoids Pon Velayutham Anandh Babu, Dongmin Liu, Elizabeth Ruth Gilbert · The Journal of Nutritional Biochemistry | 9 Sep 2013 | 543 |
| 49 | Flavonoids: promising natural compounds against viral infections Hovakim S. Zakaryan, Erik Arabyan, Adrian Oo et al. · Archives of Virology | 25 May 2017 | 539 |
| 50 | Lysosomes in the Physiology and Pathology of Cells: Contributions of Staining Methods Alex B. Novikoff · Novartis Foundation symposium | 27 May 2008 | 538 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.