Most cited papers in Biochemical Acid Research Studies
What are the most cited papers in Biochemical Acid Research Studies?
The most cited paper in Biochemical Acid Research Studies is "Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism" (Peter D. Mitchell, 1961), with 4,713 citations. Next come "Application of a Theory of Enzyme Specificity to Protein Synthesis" (2,421) and "Oxidative Stress: A Key Modulator in Neurodegenerative Diseases" (2,287).
Showing 50 of 100 papers. Every paper with more than 617 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism Peter D. Mitchell · Nature | Jul 1961 | 4,713 |
| 2 | Application of a Theory of Enzyme Specificity to Protein Synthesis Daniel E. Koshland · Proceedings of the National Academy of Sciences | Feb 1958 | 2,421 |
| 3 | Oxidative Stress: A Key Modulator in Neurodegenerative Diseases Anju Singh, Ritushree Kukreti, Luciano Saso et al. · Molecules | 22 Apr 2019 | 2,287 |
| 4 | Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes Joseph L. Evans, Ira D. Goldfine, Betty A. Maddux et al. · Endocrine Reviews | Oct 2002 | 2,239 |
| 5 | Alpha-lipoic acid as a biological antioxidant Lester Packer, Eric H. Witt, Hans Tritschler · Free Radical Biology and Medicine | Aug 1995 | 1,981 |
| 6 | THE FUNCTION OF CYTIDINE COENZYMES IN THE BIOSYNTHESIS OF PHOSPHOLIPIDES Eugene Paul Kennedy, Samuel B. Weiss · Journal of Biological Chemistry | Sep 1956 | 1,848 |
| 7 | The Original Michaelis Constant: Translation of the 1913 Michaelis–Menten Paper Kenneth Allen Johnson, Roger Sidney Goody · Biochemistry | 2 Sep 2011 | 1,462 |
| 8 | Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective Olga Khersonsky and Dan S. Tawfik · Annual Review of Biochemistry | 7 Jun 2010 | 1,415 |
| 9 | Role of calcium ions in regulation of mammalian intramitochondrial metabolism J G McCormack, Andrew P. Halestrap, Richard M. Denton · Physiological Reviews | Apr 1990 | 1,411 |
| 10 | Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming Yoichiro Mitsuishi, Keiko Taguchi, Yukie Kawatani et al. · Cancer Cell | Jul 2012 | 1,406 |
| 11 | Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Warren J. Strittmatter, Karl Heinrich Weisgraber, Daoyuan Huang et al. · Proceedings of the National Academy of Sciences | Sep 1993 | 1,371 |
| 12 | Oxidative stress and mitochondrial dysfunction in Alzheimer's disease Xinglong Wang, Wenzhang Wang, Li Li et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | Nov 2013 | 1,371 |
| 13 | Acetogenesis and the Wood–Ljungdahl pathway of CO2 fixation Stephen W. Ragsdale, Elizabeth A. Pierce · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 7 Sep 2008 | 1,352 |
| 14 | ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions Lucie I. Bruijn, Mark W. Bêcher, Michael K. Lee et al. · Neuron | Feb 1997 | 1,344 |
| 15 | Oxidative stress, mitochondrial damage and neurodegenerative diseases. Chunyan Guo, Li Sun, Xueping Chen et al. · PubMed | 25 Jul 2013 | 1,323 |
| 16 | ABAD Directly Links Aß to Mitochondrial Toxicity in Alzheimer's Disease Joyce W. Lustbader et al. · Science | 15 Apr 2004 | 1,301 |
| 17 | Biochemical, physiological and medical aspects of ubiquinone function Lars Ernster, Gustav Dallner · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | May 1995 | 1,232 |
| 18 | Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Rajesh Kumar Thimmulappa, Kim H., Sorachai S. Srisuma et al. · PubMed | 15 Sep 2002 | 1,199 |
| 19 | Prognostic factors in ALS: A critical review Adriano Chiò, Giancarlo Logroscino, Orla M. Hardiman et al. · Amyotrophic Lateral Sclerosis | 2009 | 1,184 |
| 20 | Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase. M Aviram, Mira Rosenblat, C L Bisgaier et al. · Journal of Clinical Investigation | 15 Apr 1998 | 1,174 |
| 21 | Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein. A. D. Watson, J A Berliner, Susan Y. Hama et al. · Journal of Clinical Investigation | Dec 1995 | 1,164 |
| 22 | Low-Barrier Hydrogen Bonds and Enzymic Catalysis W. W. Cleland, Maurice M. Kreevoy · Science | 24 Jun 1994 | 1,158 |
| 23 | Tyrosine hydroxylase and regulation of dopamine synthesis S. Colette Daubner, Tiffany Le, Shanzhi Wang · Archives of Biochemistry and Biophysics | 20 Dec 2010 | 1,106 |
| 24 | Chromatographic separation, identification, and analysis of phosphatides G.V. Marinetti · Journal of Lipid Research | 1962 | 1,081 |
| 25 | Lactate: the ugly duckling of energy metabolism Joshua D. Rabinowitz, Sven Enerbäck · Nature Metabolism | 20 Jul 2020 | 1,075 |
| 26 | Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing Stephen C. Cunnane et al. · Nature Reviews Drug Discovery | 24 Jul 2020 | 1,037 |
| 27 | Metabolism and function of coenzyme Q Mikael J. Turunen, Jerker M. Olsson, Gustav Dallner · Biochimica et Biophysica Acta (BBA) - Biomembranes | 6 Dec 2003 | 1,035 |
| 28 | Antioxidant and antiradical activities of l-carnitine İlhami Gülçın · Life Sciences | 16 Nov 2005 | 999 |
| 29 | The emerging role of Nrf2 in mitochondrial function Albena T. Dinkova‐Kostova, Andrey Y. Abramov · Free Radical Biology and Medicine | 11 May 2015 | 994 |
| 30 | Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential Kate Petersen Shay, Régis F. Moreau, Eric J.T. Smith et al. · Biochimica et Biophysica Acta (BBA) - General Subjects | 5 Aug 2009 | 982 |
| 31 | The effect of water on enzyme action in organic media. A. S. Zaks, Alexander M. Klibanov · Journal of Biological Chemistry | Jun 1988 | 924 |
| 32 | POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS Igal Gery, Richard K. Gershon, Byron H. Waksman · The Journal of Experimental Medicine | Jul 1972 | 912 |
| 33 | A review on the role of antioxidants in the management of diabetes and its complications Roja Rahimi, Shekoufeh Nikfar, Bagher A. Larijani et al. · Biomedicine & Pharmacotherapy | 23 Jul 2005 | 897 |
| 34 | Regulation of mitochondrial dehydrogenases by calcium ions Richard M. Denton · Biochimica et Biophysica Acta (BBA) - Bioenergetics | 21 Jan 2009 | 897 |
| 35 | A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila , and Humans Daniel K. Bricker, Eric B. Taylor, John C. Schell et al. · Science | 25 May 2012 | 891 |
| 36 | Tissue fractionation studies. 4. Comparative study of the binding of acid phosphatase, β-glucuronidase and cathepsin by rat-liver particles R. Gianetto, C. De Duve · Biochemical Journal | Mar 1955 | 886 |
| 37 | The role of oxidative stress in the onset and progression of diabetes and its complications: asummary of a Congress Series sponsored byUNESCO-MCBN, the American Diabetes Association and the German Diabetes Society P. R�sen, PP Nawroth, George Liang King et al. · Diabetes/Metabolism Research and Reviews | 2001 | 886 |
| 38 | Growth factors: Mechanism of action and relation to oncogenes Carl‐Henrik Heldin, Bengt Westermark · Cell | May 1984 | 880 |
| 39 | ‘Interfacial activation’ of lipases: facts and artifacts Robert Verger · Trends in biotechnology | 1997 | 877 |
| 40 | Adenyl Cyclase Earl W. Sutherland, Theodore W. Rall, Tara Menon · Journal of Biological Chemistry | Apr 1962 | 858 |
| 41 | Aromatic l-Amino Acid Decarboxylase Walter M. Lovenberg, Herbert Weissbach, Sidney Udenfriend · Journal of Biological Chemistry | 1962 | 853 |
| 42 | Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress. M Crompton, H Ellinger, Andreas COSTI · PubMed | Oct 1988 | 849 |
| 43 | The 'evolvability' of promiscuous protein functions Amir Aharoni, Leonid Gaidukov, Olga Khersonsky et al. · Nature Genetics | 28 Nov 2004 | 847 |
| 44 | The pharmacology of the antioxidant lipoic acid Gerreke Ph. Biewenga, Guido R.M.M. Haenen, Aalt Bast · General Pharmacology The Vascular System | Sep 1997 | 845 |
| 45 | Plant phenolic compounds and the isolation of plant enzymes W.David Loomis, J. Battaile · Phytochemistry | May 1966 | 842 |
| 46 | Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier Yossi Gilgun‐Sherki, Eldad Melamed, Daniel Offen · Neuropharmacology | Jun 2001 | 840 |
| 47 | THE SUBMITOCHONDRIAL LOCALIZATION OF MONOAMINE OXIDASE Carl A. Schnaitman, V. Gene Erwin, John W. Greenawalt · The Journal of Cell Biology | Mar 1967 | 837 |
| 48 | The Formation of 2-Keto-3-deoxyheptonic Acid in Extracts of Escherichia coli B Arthur Weissbach, Jerard Hurwitz · Journal of Biological Chemistry | Apr 1959 | 835 |
| 49 | The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life Paul John Thornalley · Biochemical Journal | Jul 1990 | 825 |
| 50 | Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications Zewen Liu, Tingyang Zhou, Alexander C. Ziegler et al. · Oxidative Medicine and Cellular Longevity | 2017 | 822 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.