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Topic · Biochemistry

Biochemical Acid Research Studies

Biochemical Acid Research Studies is a research topic within Biochemistry. Science Explorer counts 15k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the role of lipoic acid in metabolism, oxidative stress, and various health conditions such as diabetes and neurodegenerative diseases. It delves into the molecular mechanisms, therapeutic potential, and regulatory effects of lipoic acid on enzymes involved in energy metabolism and antioxidant activities. Additionally, it investigates the impact of lipoic acid on mitochondrial function, inflammation, and its potential as a treatment for metabolic diseases.

  • Lipoic Acid
  • Pyruvate Dehydrogenase Complex
  • Oxidative Stress
  • Diabetes
  • Antioxidant
  • Mitochondrial Function
  • Enzyme Regulation
  • Inflammation
  • Thiamin Diphosphate
  • Metabolic Diseases
Research works
15k
fractional, since 1950
In the world top 10%
1.5k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+9%
the tick is no change
Largest producer
China
36% of the 10 largest, 2022-now

Which countries lead Biochemical Acid Research Studies research?

By volume, China and the United States publish the most (504 and 291 works in 2022-now).

By volume, 2022-now

  1. 1 China 504 works
  2. 2 United States 291 works
  3. 3 India 135 works
  4. 4 Russia 110 works
  5. 5 Germany 70 works
  6. 6 Japan 68 works
  7. 7 Türkiye 62 works
  8. 8 Italy 59 works
  9. 9 Iran 50 works
  10. 10 United Kingdom 50 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 36.0%United States: 20.8%India: 9.7%Russia: 7.8%6 others listed: 25.7%36%largest
China504 · 36.0%United States291 · 20.8%India135 · 9.7%Russia110 · 7.8%6 others listed361 · 25.7%

Shares of the rows listed above, not of the whole node.

Which institutions lead Biochemical Acid Research Studies research?

By volume in 2022-now, Russian Academy of Sciences publishes the most Biochemical Acid Research Studies research, followed by Chinese Academy of Sciences and Jiangnan University.

Who are the leading researchers in Biochemical Acid Research Studies?

The most-cited researchers publishing on Biochemical Acid Research Studies include Giuseppe Remuzzi, Matthias Mann and John Q. Trojanowski.

  1. 1 Giuseppe Remuzzi Italy 328k citations
  2. 2 Matthias Mann Germany 308k citations
  3. 3 John Q. Trojanowski United States 286k citations
  4. 4 George M. Whitesides United States 267k citations
  5. 5 Amirhossein Sahebkar Iran 258k citations
  6. 6 Cornelia M. van Duijn Netherlands 250k citations
  7. 7 John Hardy United Kingdom 243k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Biochemical Acid Research Studies?

The most cited paper in Biochemical Acid Research Studies is "Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism" (Peter D. Mitchell, 1961), with 4,713 citations. Next come "Application of a Theory of Enzyme Specificity to Protein Synthesis" (2,421) and "Oxidative Stress: A Key Modulator in Neurodegenerative Diseases" (2,287).

Most cited papers
#PaperReleasedCitations
1 Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism Peter D. Mitchell · Nature Jul 1961 4,713
2 Application of a Theory of Enzyme Specificity to Protein Synthesis Daniel E. Koshland · Proceedings of the National Academy of Sciences Open access Feb 1958 2,421
3 Oxidative Stress: A Key Modulator in Neurodegenerative Diseases Anju Singh, Ritushree Kukreti, Luciano Saso et al. · Molecules Open access 22 Apr 2019 2,287
4 Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes Joseph L. Evans, Ira D. Goldfine, Betty A. Maddux et al. · Endocrine Reviews Oct 2002 2,239
5 Alpha-lipoic acid as a biological antioxidant Lester Packer, Eric H. Witt, Hans Tritschler · Free Radical Biology and Medicine Aug 1995 1,981
All 100 most cited papers, with filters and sorting

Where is Biochemical Acid Research Studies research done?

The largest centres of Biochemical Acid Research Studies research in 2022-now are Beijing (China), Moscow (Russia), Shanghai (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Moscow.

Largest cities, 2022-now

  1. 1 BeijingChina 52 works
  2. 2 MoscowRussia 49 works
  3. 3 ShanghaiChina 32 works
  4. 4 NanjingChina 29 works
  5. 5 HangzhouChina 25 works
  6. 6 GuangzhouChina 22 works
  7. 7 ChengduChina 20 works
  8. 8 WuxiChina 19 works
  9. 9 TianjinChina 19 works
  10. 10 TokyoJapan 17 works

Where it is the local speciality

  1. MoscowRU · 49.0 works2.4×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Biochemical Acid Research Studies than the world average.

See Biochemical Acid Research Studies on the map

Where is the best place to study Biochemical Acid Research Studies?

Among universities, judged by research, Harvard University, Jiangnan University and Sichuan University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 64.427.4%1.8×10 +76.6%
2Jiangnan UniversityChina 51.06.8%14.5×15 +40.3%
3Sichuan UniversityChina 41.626.5%2.3×9 +13.2%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Biochemical Acid Research Studies, country by country

Is Biochemical Acid Research Studies research growing?

Output in 2022-2025 was 9% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Biochemical Acid Research Studies.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Biochemical Acid Research Studies as a percentage of every work published that year, 0.0084% in 2024.

still counting0.020%0.040%0.060%Biochemical Acid Research Studies0.0093% in 202519801990200020102020

Fractional works of Biochemical Acid Research Studies over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Biochemical Acid Research Studies10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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