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Most cited papers in Biochemical effects in animals

What are the most cited papers in Biochemical effects in animals?

The most cited paper in Biochemical effects in animals is "Two new Later Stone Age sites from the Final Pleistocene in the Falémé Valley, eastern Senegal" (Ndiaye, Matar, Lespez, Laurent, Tribolo, Chantal et al., 2024), with 24,104 citations. Next come "Oxidants, antioxidants, and the degenerative diseases of aging." (5,991) and "Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α" (4,041).

Showing 50 of 100 papers. Every paper with more than 883 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Two new Later Stone Age sites from the Final Pleistocene in the Falémé Valley, eastern Senegal Ndiaye, Matar, Lespez, Laurent, Tribolo, Chantal et al. · Monash University Research Portal (Monash University) Open access 28 Mar 2024 24,104
2 Oxidants, antioxidants, and the degenerative diseases of aging. B N Ames, Mark K. Shigenaga, Tory M. Hagen · Proceedings of the National Academy of Sciences Open access Sep 1993 5,991
3 Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α Marie Lagouge, Carmen Argmann, Zachary Gerhart‐Hines et al. · Cell Open access 17 Nov 2006 4,041
4 Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options Bayani Uttara, Ajay Singh, Paolo Zamboni et al. · Current Neuropharmacology Open access Mar 2009 3,398
5 Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1 Joseph T. Rodgers, Carles Lerín, Wilhelm Haas et al. · Nature Mar 2005 3,149
6 Diabetes, oxidative stress, and antioxidants: A review Alice C. Maritim, Ruth A. Sanders, J. B. Watkins · Journal of Biochemical and Molecular Toxicology 2003 3,140
7 Free Radicals: Properties, Sources, Targets, and Their Implication in Various Diseases Phaniendra Alugoju, Dinesh Babu Jestadi, Latha Periyasamy · Indian Journal of Clinical Biochemistry Open access 14 Jul 2014 2,908
8 Free radicals, antioxidants, and nutrition Yun-Zhong Fang, Sheng Yang, Guoyao Wu · Nutrition Oct 2002 2,574
9 Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. John Baynes, Suzanne R. Thorpe · Diabetes 1999 2,449
10 PEROXIDASE-LABELED ANTIBODY A NEW METHOD OF CONJUGATION Paul K. Nakane, Akira Kawaoi · Journal of Histochemistry & Cytochemistry Open access Dec 1974 2,353
11 Oxidative Stress: A Key Modulator in Neurodegenerative Diseases Anju Singh, Ritushree Kukreti, Luciano Saso et al. · Molecules Open access 22 Apr 2019 2,287
12 Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide Peter M. Zygmunt, Jesper Petersson, David A. Andersson et al. · Nature Jul 1999 2,160
13 Hydroxyl radical scavenging activity of compatible solutes Nicholas Smirnoff, Quinton J. Cumbes · Phytochemistry 1989 2,147
14 Current research in meat color Richard A. Mancini, Melvin C. Hunt · Meat Science 25 May 2005 2,092
15 The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy David Scott Wishart, Brian D. Sykes, F.M. Richards · Biochemistry 18 Feb 1992 2,062
16 Sirtuins as regulators of metabolism and healthspan Riekelt H. Houtkooper, Eija Pirinen, Johan H. Auwerx · Nature Reviews Molecular Cell Biology ReviewOpen access 7 Mar 2012 2,025
17 Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease David Allan Butterfield, Barry B. Halliwell · Nature reviews. Neuroscience ReviewOpen access 8 Feb 2019 2,001
18 Free radical-mediated oxidation of free amino acids and amino acid residues in proteins Earl R. Stadtman, Rodney L. Levine · Amino Acids 29 Jul 2003 1,970
19 The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs. K A Reimer, J. E. Lowe, Margaret M. Rasmussen et al. · Circulation Open access Nov 1977 1,940
20 Ascorbate is an outstanding antioxidant in human blood plasma. Balz Frei, Laura J. England, B N Ames · Proceedings of the National Academy of Sciences Open access Aug 1989 1,879
21 Purification and properties Brian M. Cox, K E Opheim, H. Teschemacher et al. · Life Sciences Jun 1975 1,717
22 Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes Jill C. Milne et al. · Nature Open access 29 Nov 2007 1,707
23 SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation Matthew D. Hirschey, Tadahiro Shimazu, Eric S. Goetzman et al. · Nature Open access Mar 2010 1,706
24 Antioxidative peptides from food proteins: A review Bahareh Sarmadi, Amin Ismail · Peptides Jul 2010 1,653
25 Protein damage and degradation by oxygen radicals. I. general aspects. Kelvin J.A. Davies · Journal of Biological Chemistry Open access Jul 1987 1,640
26 Diabetes mellitus and oxidative stress—A concise review Asmat Ullah, Abad Khan, Khan Ismail · Saudi Pharmaceutical Journal Open access 5 Apr 2015 1,589
27 Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers Juha Laurén, David A. Gimbel, Haakon B. Nygaard et al. · Nature Open access Feb 2009 1,572
28 Biological studies of post-traumatic stress disorder Roger K. Pitman, Ann M. Rasmusson, Karestan Chase Koenen et al. · Nature reviews. Neuroscience ReviewOpen access 10 Oct 2012 1,557
29 Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity Vittorio Calabrese, Cesare Mancuso, Menotti Calvani et al. · Nature reviews. Neuroscience Review 20 Sep 2007 1,552
30 Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology José Manuel Matés · Toxicology Nov 2000 1,527
31 The Chemistry of Curcumin: From Extraction to Therapeutic Agent Kavirayani Indira Priyadarsini · Molecules Open access Dec 2014 1,506
32 Role of Free Radicals in the Neurodegenerative Diseases Barry B. Halliwell · Drugs & Aging 2001 1,505
33 Potential Role of Carotenoids as Antioxidants in Human Health and Disease Joanna Fiedor, Kvĕtoslava Burda · Nutrients Open access 27 Jan 2014 1,439
34 Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state Christian J. Pike, Daniel J. Burdick, AJ Walencewicz et al. · Journal of Neuroscience Open access Apr 1993 1,432
35 MYELINATION IN RAT BRAIN: METHOD OF MYELIN ISOLATION1 William T. Norton, Shirley E. Poduslo · Journal of Neurochemistry Oct 1973 1,420
36 [Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats]. H. Druckrey, R. Preußmann, Stan Ivankovic et al. · PubMed 1967 1,409
37 Small heat shock proteins are molecular chaperones. Ursula Jakob, Matthias Gaestel, Katrin Engel et al. · Journal of Biological Chemistry Open access 1993 1,397
38 Carp Muscle Calcium-binding Protein Robert H. Kretsinger, Clive E. Nockolds · Journal of Biological Chemistry Open access May 1973 1,359
39 Antioxidant Activity of Proteins and Peptides Ryan J. Elias, Sarah S. Kellerby, Eric A. Decker · Critical Reviews in Food Science and Nutrition 4 May 2008 1,350
40 Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans Silvie Timmers, Ellen Konings, Lena Bilet et al. · Cell Metabolism Open access Nov 2011 1,320
41 Advanced Glycation End Products in Foods and a Practical Guide to Their Reduction in the Diet Jaime Uribarri, Sandra Woodruff, Susan A. Goodman et al. · Journal of the American Dietetic Association Open access 23 May 2010 1,289
42 Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States Mark P. Mattson, Thiruma Valavan Arumugam · Cell Metabolism Open access Jun 2018 1,279
43 Oxidative Stress and the Central Nervous System Samina Salim · Journal of Pharmacology and Experimental Therapeutics Open access 18 Oct 2016 1,247
44 Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease Mark A. Smith, Peggy L. Richey Harris, Lawrence M. Sayre et al. · Journal of Neuroscience Open access 15 Apr 1997 1,247
45 Hormesis defined Mark P. Mattson · Ageing Research Reviews ReviewOpen access 6 Dec 2007 1,246
46 Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation David B. Lombard, Frederick W. Alt, Hwei-Ling Cheng et al. · Molecular and Cellular Biology Open access 9 Oct 2007 1,227
47 Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose Paul John Thornalley, Annika LANGBORG, Harjit S. Minhas · Biochemical Journal Open access 8 Nov 1999 1,214
48 International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function. Eric A. Barnard, Phil Skolnick, R. W. Olsen et al. · PubMed Jun 1998 1,210
49 Glutamate receptors, neurotoxicity and neurodegeneration Anthony Lau, Michael Tymianski · Pflügers Archiv - European Journal of Physiology 13 Mar 2010 1,207
50 Effect of Environmental Factors on the Kinetics of Insulin Fibril Formation: Elucidation of the Molecular Mechanism Liza Nielsen, Ritu Khurana, Alisa C. Coats et al. · Biochemistry 24 Apr 2001 1,197

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.