Most cited papers in Biotin and Related Studies
What are the most cited papers in Biotin and Related Studies?
The most cited paper in Biotin and Related Studies is "An automated method for finding molecular complexes in large protein interaction networks" (Gary D. Bader, Christopher W.V. Hogue, 2003), with 6,387 citations. Next come "A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae" (4,754) and "The determination of enzyme inhibitor constants" (4,083).
Showing 50 of 101 papers. Every paper with more than 873 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | An automated method for finding molecular complexes in large protein interaction networks Gary D. Bader, Christopher W.V. Hogue · BMC Bioinformatics | 13 Jan 2003 | 6,387 |
| 2 | A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae Peter H Uetz, Loïc Giot, Gerard Cagney et al. · Nature | Feb 2000 | 4,754 |
| 3 | The determination of enzyme inhibitor constants Martin Dixon · Biochemical Journal | Aug 1953 | 4,083 |
| 4 | Sulforhodamine B colorimetric assay for cytotoxicity screening Vanicha Vichai, Kanyawim Kirtikara · Nature Protocols | Aug 2006 | 3,730 |
| 5 | A comprehensive two-hybrid analysis to explore the yeast protein interactome Takashi Ito, Tomoko Chiba, Ritsuko Ozawa et al. · Proceedings of the National Academy of Sciences | 13 Mar 2001 | 3,602 |
| 6 | The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins William H. Landschulz, Peter F. Johnson, Steven Lanier McKnight · Science | 24 Jun 1988 | 3,521 |
| 7 | Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin Atsushi Miyawaki, Juan Llopis, Roger Heim et al. · Nature | 28 Aug 1997 | 3,272 |
| 8 | Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J L Cordell, Brunangelo Falini, Wendy N. Erber et al. · Journal of Histochemistry & Cytochemistry | Feb 1984 | 3,212 |
| 9 | A Fast Flexible Docking Method using an Incremental Construction Algorithm Matthias Rarey, BERND J. KRÄMER, Thomas Lengauer et al. · Journal of Molecular Biology | Aug 1996 | 2,848 |
| 10 | Severe Psoriasis – Oral Therapy with a New Retinoid Tove Fredriksson, U. Pettersson · Dermatologica | 14 Oct 2009 | 2,758 |
| 11 | HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis Georgyi V. Los, Lance P. Encell, Mark G. McDougall et al. · ACS Chemical Biology | Jun 2008 | 2,688 |
| 12 | SNAREs — engines for membrane fusion Reinhard Jahn, Richard H. Scheller · Nature Reviews Molecular Cell Biology | 16 Aug 2006 | 2,675 |
| 13 | A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells Kyle J. Roux, Dae In Kim, Manfred Raida et al. · The Journal of Cell Biology | 12 Mar 2012 | 2,636 |
| 14 | Dynamic strength of molecular adhesion bonds Erastus W. Evans, Ken P. Ritchie · Biophysical Journal | Apr 1997 | 2,582 |
| 15 | Efficient Trace-labelling of Proteins with Iodine Arthur Sproul McFarlane · Nature | 5 Jul 1958 | 2,560 |
| 16 | Pathview: an R/Bioconductor package for pathway-based data integration and visualization Weijun Luo, Cory Brouwer · Bioinformatics | 4 Jun 2013 | 2,487 |
| 17 | A Human Protein-Protein Interaction Network: A Resource for Annotating the Proteome Ulrich Stelzl et al. · Cell | Sep 2005 | 2,439 |
| 18 | A rapid radiochemical method for the determination of choline acetyltransferase Frode Fonnum · Journal of Neurochemistry | Feb 1975 | 2,403 |
| 19 | Efficient proximity labeling in living cells and organisms with TurboID Tess Caroline Branon, Justin A. Bosch, Ariana D. Sanchez et al. · Nature Biotechnology | 20 Aug 2018 | 2,338 |
| 20 | Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. G M Brodeur, Jon Pritchard, Frank Berthold et al. · Journal of Clinical Oncology | Aug 1993 | 2,327 |
| 21 | Mechanisms of intracellular protein transport James Edward Rothman · Nature | Nov 1994 | 2,298 |
| 22 | A general method for the covalent labeling of fusion proteins with small molecules in vivo Antje Keppler, Susanne Gendreizig, Thomas Gronemeyer et al. · Nature Biotechnology | 9 Dec 2002 | 2,042 |
| 23 | PROTEIN PRENYLATION: Molecular Mechanisms and Functional Consequences Fang L. Zhang, Patrick J. Casey · Annual Review of Biochemistry | Jun 1996 | 2,029 |
| 24 | Reaching for high-hanging fruit in drug discovery at protein–protein interfaces James A. Wells, Christopher L. McClendon · Nature | Dec 2007 | 1,989 |
| 25 | Heterologous protein expression in the methylotrophic yeast Pichia pastoris Joan Lin Cereghino, James M. Cregg · FEMS Microbiology Reviews | 2000 | 1,968 |
| 26 | STITCH 5: augmenting protein–chemical interaction networks with tissue and affinity data Damian Szklarczyk, Alberto Santos, Christian von Mering et al. · Nucleic Acids Research | 20 Nov 2015 | 1,791 |
| 27 | Fluorescence detection in automated DNA sequence analysis Lloyd M. Smith, Jane Z. Sanders, Robert Kaiser et al. · Nature | Jun 1986 | 1,720 |
| 28 | The leucine-rich repeat as a protein recognition motif Boštjan Kobe · Current Opinion in Structural Biology | Dec 2001 | 1,705 |
| 29 | THE CYTOCHEMISTRY AND ULTRASTRUCTURE OF POLYPEPTIDE HORMONE-PRODUCING CELLS OF THE APUD SERIES AND THE EMBRYOLOGIC, PHYSIOLOGIC AND PATHOLOGIC IMPLICATIONS OF THE CONCEPT A. G. E. Pearse · Journal of Histochemistry & Cytochemistry | May 1969 | 1,686 |
| 30 | Abnormal Behavior Associated with a Point Mutation in the Structural Gene for Monoamine Oxidase A Han G. Brunner, Marcel R. Nelen, Xandra Owens Breakefield et al. · Science | 22 Oct 1993 | 1,661 |
| 31 | A Comparative Study of the Peroxidase-antiperoxidase Method and an Avidin-Biotin Complex Method for Studying Polypeptide Hormones with Radioimmunoassay Antibodies Su-Ming Hsu, Laurence Raine, Herbert Fanger · American Journal of Clinical Pathology | May 1981 | 1,655 |
| 32 | Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae Scott B. Ficarro, Mark L. McCleland, P. Todd Stukenberg et al. · Nature Biotechnology | Mar 2002 | 1,642 |
| 33 | Architecture of the human interactome defines protein communities and disease networks Edward L. Huttlin et al. · Nature | May 2017 | 1,587 |
| 34 | Visualization of Interactions among bZIP and Rel Family Proteins in Living Cells Using Bimolecular Fluorescence Complementation Chang-Deng Hu, Yurii V. Chinenov, Tom Klaus Kerppola · Molecular Cell | Apr 2002 | 1,580 |
| 35 | Bioanalytical Method Validation—A Revisit with a Decade of Progress Vinod P. Shah, Kamal K. Midha, John W. A. Findlay et al. · Pharmaceutical Research | Dec 2000 | 1,577 |
| 36 | Specific Covalent Labeling of Recombinant Protein Molecules Inside Live Cells B. Albert Griffin, Stephen Adams, Roger Y. Tsien · Science | 10 Jul 1998 | 1,564 |
| 37 | Directed evolution of APEX2 for electron microscopy and proximity labeling Stephanie S Lam, Jeffrey D. Martell, Kimberli J. Kamer et al. · Nature Methods | 24 Nov 2014 | 1,498 |
| 38 | PRODIGY: a web server for predicting the binding affinity of protein–protein complexes Li C. Xue, João Pglm Rodrigues, Panagiotis L. Kastritis et al. · Bioinformatics | 8 Aug 2016 | 1,484 |
| 39 | Statin-Associated Myopathy Paul D. Thompson, Priscilla M. Clarkson, Richard H. Karas · JAMA | Apr 2003 | 1,453 |
| 40 | THE EFFECT OF AGE ON THE NON‐HAEMIN IRON IN THE HUMAN BRAIN Bo Hallgren, Patrick Sourander · Journal of Neurochemistry | Oct 1958 | 1,453 |
| 41 | Minimization of variation in the response to different proteins of the Coomassie blue G dye-binding assay for protein Steve M. Read, D. H. Northcote · Analytical Biochemistry | Sep 1981 | 1,428 |
| 42 | Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging Jeffrey D. Martell, Alice Y. Ting, Hyun‐Woo Rhee et al. · DSpace@MIT (Massachusetts Institute of Technology) | Sep 2012 | 1,417 |
| 43 | A network of protein–protein interactions in yeast Benno Schwikowski, Peter H Uetz, Stanley Fields · Nature Biotechnology | Dec 2000 | 1,386 |
| 44 | Protein Radicals in Enzyme Catalysis JoAnne Stubbe, Wilfred A. van der Donk · Chemical Reviews | 19 Mar 1998 | 1,383 |
| 45 | CytoNCA: A cytoscape plugin for centrality analysis and evaluation of protein interaction networks Yu Fei Tang, Min Li, Jianxin Wang et al. · Biosystems | 17 Nov 2014 | 1,358 |
| 46 | Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB Karen K. Yamamoto, Guillermo Avalos Gonzalez, William Biggs et al. · Nature | Aug 1988 | 1,324 |
| 47 | Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry Benjamin F. Cravatt, Aaron Wright, John W. Kozarich · Annual Review of Biochemistry | 26 Mar 2008 | 1,295 |
| 48 | A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids MK Gaitonde · Biochemical Journal | Aug 1967 | 1,234 |
| 49 | Structural Origins of High-Affinity Biotin Binding to Streptavidin Patricia C Weber, D.H. Ohlendorf, John J. Wendoloski et al. · Science | 6 Jan 1989 | 1,228 |
| 50 | Structure-Function Relationships in the Vitamin D Endocrine System* R. Bouillon, William H. Okamura, Anthony W. Norman · Endocrine Reviews | Apr 1995 | 1,199 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.