Topic · Cancer Cells and Metastasis
Most cited papers in Cancer Cells and Metastasis
What are the most cited papers in Cancer Cells and Metastasis?
The most cited paper in Cancer Cells and Metastasis is "Hallmarks of Cancer: The Next Generation" (Douglas Hanahan, Robert A. Weinberg, 2011), with 67,836 citations. Next come "The Hallmarks of Cancer" (28,893) and "Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement" (18,014).
Showing 50 of 100 papers. Every paper with more than 2,352 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Hallmarks of Cancer: The Next Generation Douglas Hanahan, Robert A. Weinberg · Cell | Mar 2011 | 67,836 |
| 2 | The Hallmarks of Cancer Douglas Hanahan, Robert A. Weinberg · Cell | 2000 | 28,893 |
| 3 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Massimo Dominici, Katarina Le Blanc, Ingo Mueller et al. · Cytotherapy | 2006 | 18,014 |
| 4 | Inferring tumour purity and stromal and immune cell admixture from expression data Kosuke Yoshihara, Maria Shahmoradgoli, Emmanuel Martínez et al. · Nature Communications | 11 Oct 2013 | 10,966 |
| 5 | Prospective identification of tumorigenic breast cancer cells Muhammad Al‐Hajj, Max S. Wicha, Adalberto Benito‐Hernández et al. · Proceedings of the National Academy of Sciences | 10 Mar 2003 | 10,455 |
| 6 | The basics of epithelial-mesenchymal transition Raghu K. Kalluri, Robert A. Weinberg · Journal of Clinical Investigation | Jun 2009 | 10,281 |
| 7 | Tumor Angiogenesis: Therapeutic Implications Louis M. Sherwood, Edith E. Parris, Judah Folkman · New England Journal of Medicine | 18 Nov 1971 | 10,238 |
| 8 | Epithelial-Mesenchymal Transitions in Development and Disease Jean Paul Thiery, Hervé Acloque, Ruby Yun‐Ju Huang et al. · Cell | Nov 2009 | 10,099 |
| 9 | Stem cells, cancer, and cancer stem cells Tannishtha Reya, Sean J. Morrison, Michael F. Clarke et al. · Nature | Nov 2001 | 9,797 |
| 10 | The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells Sendurai A. Mani, Wenjun Guo, Mai-Jing Liao et al. · Cell | May 2008 | 8,810 |
| 11 | The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity Jordi Barretina et al. · Nature | 27 Mar 2012 | 8,623 |
| 12 | Molecular mechanisms of epithelial–mesenchymal transition Samy Lamouille, Jian Xu, Rik Derynck · Nature Reviews Molecular Cell Biology | 21 Feb 2014 | 8,337 |
| 13 | Microenvironmental regulation of tumor progression and metastasis Daniela F. Quail, Johanna A. Joyce · Nature Medicine | Nov 2013 | 8,290 |
| 14 | Multilineage Cells from Human Adipose Tissue: Implications for Cell-Based Therapies Patricia A. Zuk, Min Zhu, Hiroshi Mizuno et al. · Tissue Engineering | Apr 2001 | 8,044 |
| 15 | Identification of human brain tumour initiating cells Sheila Kumari Singh, Cynthia E Hawkins, Ian D. Clarke et al. · Nature | Nov 2004 | 7,487 |
| 16 | Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature | 29 Mar 2009 | 7,361 |
| 17 | Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis Douglas Hanahan, Judah Folkman · Cell | Aug 1996 | 6,916 |
| 18 | Epithelial–mesenchymal transitions in tumour progression Jean Paul Thiery · Nature reviews. Cancer | Jun 2002 | 6,738 |
| 19 | Glioma stem cells promote radioresistance by preferential activation of the DNA damage response Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature | 18 Oct 2006 | 6,478 |
| 20 | Identification of stem cells in small intestine and colon by marker gene Lgr5 Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature | Oct 2007 | 5,813 |
| 21 | The immune contexture in human tumours: impact on clinical outcome Wolf H. Fridman, Franck Pagès, Catherine Sautès‐Fridman et al. · Nature reviews. Cancer | 15 Mar 2012 | 5,087 |
| 22 | A Perspective on Cancer Cell Metastasis Christine Louise Chaffer, Robert A. Weinberg · Science | 24 Mar 2011 | 4,934 |
| 23 | Identification of a cancer stem cell in human brain tumors. Sheila Kumari Singh, Ian D. Clarke, Mizuhiko Terasaki et al. · PubMed | 15 Sep 2003 | 4,896 |
| 24 | Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment Douglas Hanahan, Lisa M. Coussens · Cancer Cell | Mar 2012 | 4,765 |
| 25 | The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited Isaiah J. Fidler · Nature reviews. Cancer | 30 May 2003 | 4,744 |
| 26 | Geometric Control of Cell Life and Death Christopher S. Chen, Milan Mrksich, Sui Huang et al. · Science | 30 May 1997 | 4,691 |
| 27 | Sox9 Modulates Proliferation and Expression of Osteogenic Markers of Adipose-Derived Stem Cells (ASC) Sabine Stöckl, Claudia Göttl, Joachim K. Grifka et al. · Cellular Physiology and Biochemistry | 2013 | 4,664 |
| 28 | Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer Massimo Cristofanilli, George Thomas Budd, Matthew J. Ellis et al. · New England Journal of Medicine | 18 Aug 2004 | 4,641 |
| 29 | EMT: 2016 Maria Angela Nieto, Ruby Yun‐Ju Huang, Rebecca Jackson et al. · Cell | Jun 2016 | 4,612 |
| 30 | Fibroblasts in cancer Raghu K. Kalluri, Michael Zeisberg · Nature reviews. Cancer | 30 Mar 2006 | 4,547 |
| 31 | The biology and function of fibroblasts in cancer Raghu K. Kalluri · Nature reviews. Cancer | 23 Aug 2016 | 4,462 |
| 32 | Cancer Metastasis: Building a Framework Gaorav P. Gupta, Joan Massagué · Cell | Nov 2006 | 4,346 |
| 33 | Tumor Metastasis: Molecular Insights and Evolving Paradigms Scott Valastyan, Robert A. Weinberg · Cell | Oct 2011 | 4,179 |
| 34 | A human colon cancer cell capable of initiating tumour growth in immunodeficient mice Catherine Adell O'Brien, Aaron F. Pollett, Steven Gallinger et al. · Nature | 19 Nov 2006 | 4,107 |
| 35 | New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer Anushka Dongre, Robert A. Weinberg · Nature Reviews Molecular Cell Biology | 20 Nov 2018 | 4,104 |
| 36 | ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome Christophe Ginestier, Min Hee Hur, Emmanuelle Charafe‐Jauffret et al. · Cell stem cell | Nov 2007 | 4,039 |
| 37 | Identification and expansion of human colon-cancer-initiating cells Lucia Ricci‐Vitiani, Dario Giuseppe Lombardi, Emanuela Pilozzi et al. · Nature | 19 Nov 2006 | 4,008 |
| 38 | The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth Karin E. de Visser, Johanna A. Joyce · Cancer Cell | Mar 2023 | 4,002 |
| 39 | Complex networks orchestrate epithelial–mesenchymal transitions Jean Paul Thiery, Jonathan Paul Sleeman · Nature Reviews Molecular Cell Biology | Feb 2006 | 3,974 |
| 40 | Dissemination and growth of cancer cells in metastatic sites Ann F. Chambers, Alan C. Groom, Ian C. MacDonald · Nature reviews. Cancer | Aug 2002 | 3,963 |
| 41 | A framework for advancing our understanding of cancer-associated fibroblasts Erik A. Sahai et al. · Nature reviews. Cancer | 24 Jan 2020 | 3,962 |
| 42 | Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis Jing Lan Yang, Sendurai A. Mani, Joana Liu Donaher et al. · Cell | Jun 2004 | 3,886 |
| 43 | Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium Toshiro Sato, Daniel E. Stange, Marc Ferrante et al. · Gastroenterology | 3 Sep 2011 | 3,882 |
| 44 | Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion Akira Orimo, Piyush B. Gupta, Dennis C. Sgroi et al. · Cell | May 2005 | 3,791 |
| 45 | Microenvironmental regulation of metastasis Johanna A. Joyce, Jeffrey W. Pollard · Nature reviews. Cancer | 12 Mar 2008 | 3,730 |
| 46 | Wnt signalling in stem cells and cancer Tannishtha Reya, Hans C. Clevers · Nature | 13 Apr 2005 | 3,705 |
| 47 | The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression Amparo Martínez Cano, Mirna Pérez‐Moreno, Isabel Rodrigo et al. · Nature Cell Biology | 13 Jan 2000 | 3,685 |
| 48 | Isolation of rare circulating tumour cells in cancer patients by microchip technology Sunitha Nagrath, Lecia Van Dam Sequist, Shyamala Maheswaran et al. · Nature | Dec 2007 | 3,572 |
| 49 | Tumorigenesis and the angiogenic switch Gabriele Bergers, Laura E. Benjamin · Nature reviews. Cancer | 30 May 2003 | 3,553 |
| 50 | Cancer stem cells in solid tumours: accumulating evidence and unresolved questions Jane E. Visvader, Geoffrey J. Lindeman · Nature reviews. Cancer | 11 Sep 2008 | 3,485 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.