Topic · Cardiac Ischemia and Reperfusion
Most cited papers in Cardiac Ischemia and Reperfusion
What are the most cited papers in Cardiac Ischemia and Reperfusion?
The most cited paper in Cardiac Ischemia and Reperfusion is "Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium." (Charles E. Murry, Robert B. Jennings, K A Reimer, 1986), with 7,857 citations. Next come "Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release" (5,423) and "Myocardial Reperfusion Injury" (3,755).
Showing 50 of 99 papers. Every paper with more than 873 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Charles E. Murry, Robert B. Jennings, K A Reimer · Circulation | Nov 1986 | 7,857 |
| 2 | Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release Dmitry B. Zorov, Magdalena Juhaszova, Steven J. Sollott · Physiological Reviews | Jul 2014 | 5,423 |
| 3 | Myocardial Reperfusion Injury Derek M. Yellon, Derek John Hausenloy · New England Journal of Medicine | 12 Sep 2007 | 3,755 |
| 4 | BCL-2 family members and the mitochondria in apoptosis Atan Gross, James M. McDonnell, S J Korsmeyer · Genes & Development | Aug 1999 | 3,664 |
| 5 | Ischemia and reperfusion—from mechanism to translation Holger K. Eltzschig, Tobias de la Garza Eckle · Nature Medicine | Nov 2011 | 3,427 |
| 6 | A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats A.J. de Bold, Heidi Borenstein, Anthony T. Veress et al. · Life Sciences | 1981 | 3,166 |
| 7 | Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS Edward T. Chouchani et al. · Nature | 4 Nov 2014 | 2,927 |
| 8 | The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen Alberto Boveris, Britton Chance · Biochemical Journal | 15 Jul 1973 | 2,626 |
| 9 | Myocardial ischemia-reperfusion injury: a neglected therapeutic target Derek John Hausenloy, Derek M. Yellon · Journal of Clinical Investigation | 2 Jan 2013 | 2,383 |
| 10 | Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts Michael R. Bristow, Robert Ginsburg, Wayne A. Minobe et al. · New England Journal of Medicine | 22 Jul 1982 | 2,284 |
| 11 | The Biological Basis for Cardiac Repair After Myocardial Infarction Sumanth D. Prabhu, Nikolaos G. Frangogiannis · Circulation Research | 24 Jun 2016 | 2,275 |
| 12 | Cell Biology of Ischemia/Reperfusion Injury Theodore John Kalogeris, Christopher P. Baines, Maike Krenz et al. · International review of cytology | 2012 | 2,202 |
| 13 | Physiological roles and properties of potassium channels in arterial smooth muscle Mark Tyler Nelson, John M. Quayle · American Journal of Physiology-Cell Physiology | Apr 1995 | 2,168 |
| 14 | Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning Zhi‐Qing Zhao, Joel S. Corvera, Michael Emanuel Halkos et al. · American Journal of Physiology-Heart and Circulatory Physiology | Aug 2003 | 2,060 |
| 15 | The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs. K A Reimer, J. E. Lowe, Margaret M. Rasmussen et al. · Circulation | Nov 1977 | 1,940 |
| 16 | The “No-Reflow” Phenomenon after Temporary Coronary Occlusion in the Dog Robert Alan Kloner, Charles Edgar Ganote, Robert B. Jennings · Journal of Clinical Investigation | Dec 1974 | 1,846 |
| 17 | Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase Yibing Li, Ting‐Ting Huang, Elaine J. Carlson et al. · Nature Genetics | Dec 1995 | 1,791 |
| 18 | Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage Dennis W. Choi · Trends in Neurosciences | 1988 | 1,746 |
| 19 | Pathophysiology of ischaemia-reperfusion injury Donna L. Carden, Daniel Neil Granger · The Journal of Pathology | Feb 2000 | 1,746 |
| 20 | Reconstitution of I KATP : An Inward Rectifier Subunit Plus the Sulfonylurea Receptor Nobuya Inagaki, Tohru Gonoi, John P. Clement et al. · Science | 17 Nov 1995 | 1,728 |
| 21 | Effect of Atenolol on Mortality and Cardiovascular Morbidity after Noncardiac Surgery Dennis T. Mangano, Elizabeth L. Layug, Arthur W. Wallace et al. · New England Journal of Medicine | 5 Dec 1996 | 1,707 |
| 22 | Apoptosis in the Failing Human Heart Giorgio Olivetti, Rakesh K. Abbi, Federico Quaini et al. · New England Journal of Medicine | 17 Apr 1997 | 1,690 |
| 23 | Negative Inotropic Effects of Cytokines on the Heart Mediated by Nitric Oxide Mitchell S. Finkel, Carmine V. Oddis, Timothy D. Jacob et al. · Science | 17 Jul 1992 | 1,644 |
| 24 | Production of Reactive Oxygen Species by Mitochondria Qun Chen, Edwin J. Vazquez, Shadi Moghaddas et al. · Journal of Biological Chemistry | Sep 2003 | 1,610 |
| 25 | Optimal Medical Therapy With or Without Percutaneous Coronary Intervention to Reduce Ischemic Burden Leslee J. Shaw et al. · Circulation | 11 Feb 2008 | 1,609 |
| 26 | Inwardly Rectifying Potassium Channels: Their Structure, Function, and Physiological Roles Hiroshi Hibino, Atsushi Inanobe, Kazuharu Furutani et al. · Physiological Reviews | 2010 | 1,572 |
| 27 | Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase Harry Ischiropoulos, Ling Zhu, Jun Chen et al. · Archives of Biochemistry and Biophysics | Nov 1992 | 1,501 |
| 28 | Reperfusion injury and reactive oxygen species: The evolution of a concept Daniel Neil Granger, Peter R. Kvietys · Redox Biology | 19 Oct 2015 | 1,488 |
| 29 | Role of oxidative stress in cardiovascular diseases Naranjan S. Dhalla, Rana M. Temsah, Thomas Netticadan · Journal of Hypertension | Jun 2000 | 1,469 |
| 30 | Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury Elizabeth Murphy, Charles Steenbergen · Physiological Reviews | Apr 2008 | 1,459 |
| 31 | Apoptosis in Myocytes in End-Stage Heart Failure Jagat Narula, Nezam Haider, Renu Virmani et al. · New England Journal of Medicine | 17 Oct 1996 | 1,450 |
| 32 | Reperfusion injury induces apoptosis in rabbit cardiomyocytes. Roberta A. Gottlieb, Katharine O. Burleson, Robert Alan Kloner et al. · Journal of Clinical Investigation | Oct 1994 | 1,446 |
| 33 | The BCL-2 Family Reunion Jerry E. Chipuk, Tudor Moldoveanu, Fabien Llambi et al. · Molecular Cell | Feb 2010 | 1,431 |
| 34 | Cardiac Energy Metabolism in Heart Failure Gary D. Lopaschuk, Qutuba G. Karwi, Rong Tian et al. · Circulation Research | 13 May 2021 | 1,406 |
| 35 | Part 4: Advanced Life Support Clifton W. Callaway et al. · Circulation | 15 Oct 2015 | 1,394 |
| 36 | Swine as Models in Biomedical Research and Toxicology Testing M. Michael Swindle, Andy Makin, A. J. Herron et al. · Veterinary Pathology | 25 Mar 2011 | 1,387 |
| 37 | Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion. Karin Przyklenk, Barbara Bauer, Michel Ovize et al. · Circulation | Mar 1993 | 1,385 |
| 38 | Myocardial reperfusion: a double-edged sword? Eugene Braunwald, Robert Alan Kloner · Journal of Clinical Investigation | Nov 1985 | 1,371 |
| 39 | Current Mechanistic Concepts in Ischemia and Reperfusion Injury Meng‐Yu Wu, Giou-Teng Yiang, Wan-Ting Liao et al. · Cellular Physiology and Biochemistry | 2018 | 1,360 |
| 40 | L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation Richard M. J. Palmer, Daryl D. Rees, DAVID S. ASHTON et al. · Biochemical and Biophysical Research Communications | Jun 1988 | 1,355 |
| 41 | Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart. G. S. Liu, Jon D. Thornton, Donna M. Van Winkle et al. · Circulation | Jul 1991 | 1,354 |
| 42 | Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction Christophe A. Piot et al. · New England Journal of Medicine | 30 Jul 2008 | 1,323 |
| 43 | Effect of Pravastatin on Outcomes after Cardiac Transplantation JON A. KOBASHIGAWA, Steven Katznelson, Hillel Laks et al. · New England Journal of Medicine | 7 Sep 1995 | 1,311 |
| 44 | Oxygen, oxidative stress, hypoxia, and heart failure Frank J. Giordano · Journal of Clinical Investigation | Mar 2005 | 1,300 |
| 45 | Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial Stefan P. Janssens et al. · The Lancet | 2006 | 1,297 |
| 46 | Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology Tianzheng Yu, James L. Robotham, Yisang Yoon · Proceedings of the National Academy of Sciences | 13 Feb 2006 | 1,265 |
| 47 | Myocardial ischaemia–reperfusion injury and cardioprotection in perspective Gerd Heusch · Nature Reviews Cardiology | 3 Jul 2020 | 1,242 |
| 48 | Oxidative stress and heart failure Hiroyuki Tsutsui, Shintaro Kinugawa, Shouji Matsushima · American Journal of Physiology-Heart and Circulatory Physiology | 24 Sep 2011 | 1,236 |
| 49 | Mitochondrial permeability transition pore opening during myocardial reperfusion—a target for cardioprotection Andrew P. Halestrap · Cardiovascular Research | 24 Nov 2003 | 1,218 |
| 50 | Superoxide radicals in feline intestinal ischemia D. Neil Granger, Gianfranco Rutili, Joe M. McCord · Gastroenterology | Jul 1981 | 1,214 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.