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Topic · Catalytic C–H Functionalization Methods

Most cited papers in Catalytic C–H Functionalization Methods

Catalytic C–H Functionalization Methods

What are the most cited papers in Catalytic C–H Functionalization Methods?

The most cited paper in Catalytic C–H Functionalization Methods is "Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis" (Christopher K. Prier, Danica A. Rankic, David W. C. MacMillan, 2013), with 9,625 citations. Next come "Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions" (6,127) and "Palladium(II)‐Catalyzed CH Activation/CC Cross‐Coupling Reactions: Versatility and Practicality" (4,122).

Showing 50 of 99 papers. Every paper with more than 1,432 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis Christopher K. Prier, Danica A. Rankic, David W. C. MacMillan · Chemical Reviews ReviewOpen access 19 Mar 2013 9,625
2 Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions Thomas W. Lyons, Melanie Sarah Sanford · Chemical Reviews ReviewOpen access 15 Jan 2010 6,127
3 Palladium(II)‐Catalyzed CH Activation/CC Cross‐Coupling Reactions: Versatility and Practicality Xiao Chen, Keary M. Engle, Dong‐Hui Wang et al. · Angewandte Chemie International Edition Open access 25 Jun 2009 4,122
4 The Heck Reaction as a Sharpening Stone of Palladium Catalysis I. P. Beletskaya, Andrei V. Cheprakov · Chemical Reviews Review 21 Jul 2000 3,914
5 Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds Charles See Yeung, Vy M. Dong · Chemical Reviews Review 9 Mar 2011 3,866
6 Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation Denise A. Colby, Robert George Bergman, Jonathan A. Ellman · Chemical Reviews ReviewOpen access 13 May 2009 3,695
7 Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation Dino Alberico, Mark E. Scott, Mark Lautens · Chemical Reviews Review 2007 3,637
8 The Palladium‐Catalyzed Cross‐Coupling Reactions of Organotin Reagents with Organic Electrophiles [New Synthetic Methods (58)] JOHN K. STILLE · Angewandte Chemie International Edition in English Jun 1986 3,392
9 Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope Lutz Ackermann · Chemical Reviews Review 9 Mar 2011 3,370
10 Photoredox Catalysis in Organic Chemistry Megan H. Shaw, Jack Twilton, David W. C. MacMillan · The Journal of Organic Chemistry Open access Aug 2016 3,239
11 Asymmetric Transition Metal-Catalyzed Allylic Alkylations Barry M. Trost, David L. Van Vranken · Chemical Reviews Review 1996 3,206
12 Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize Carin C. C. Johansson Seechurn, Matthew O. Kitching, Thomas J. Colacot et al. · Angewandte Chemie International Edition Open access 9 May 2012 3,024
13 CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals Junichiro Yamaguchi, Atsushi D. Yamaguchi, Kenichiro Itami · Angewandte Chemie International Edition 6 Aug 2012 2,994
14 Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions Paula Ruiz‐Castillo, Stephen L. Buchwald · Chemical Reviews ReviewOpen access 30 Sep 2016 2,987
15 The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry Rafael Chinchílla, Carmén Nájera · Chemical Reviews Review 17 Feb 2007 2,964
16 Cross-Dehydrogenative Coupling (CDC): Exploring C−C Bond Formations beyond Functional Group Transformations Chao‐Jun Li · Accounts of Chemical Research 16 Dec 2008 2,780
17 Understanding and exploiting C–H bond activation Jay A. Labinger, John E. Bercaw · Nature May 2002 2,775
18 C−H Activation for the Construction of C−B Bonds Ibraheem A. I. Mkhalid, Jonathan H. Barnard, Todd B. Marder et al. · Chemical Reviews Review 22 Dec 2009 2,769
19 Transition‐Metal‐Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage Lutz Ackermann, R. Vicente, Anant Ramakant Kapdi · Angewandte Chemie International Edition 8 Dec 2009 2,751
20 Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization Percia B. Arockiam, Christian Bruneau, Pierre Henri Dixneuf · Chemical Reviews Review 31 Aug 2012 2,741
21 Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions Keary M. Engle, Tian‐Sheng Mei, Masayuki Wasa et al. · Accounts of Chemical Research Open access 14 Dec 2011 2,726
22 Palladium‐Catalyzed Cross‐Coupling Reactions in Total Synthesis Kyriacos Costa Nicolaou, Paul G. Bulger, David Šarlah · Angewandte Chemie International Edition 30 Jun 2005 2,714
23 Palladium-Catalyzed Coupling Reactions of Aryl Chlorides Adam F. Littke, Gregory C. Fu · Angewandte Chemie International Edition 14 Nov 2002 2,698
24 Visible light photocatalysis as a greener approach to photochemical synthesis Tehshik P. Yoon, Michael A. Ischay, Juana Du · Nature Chemistry 23 Jun 2010 2,684
25 Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands Rubén Martı́n, Stephen L. Buchwald · Accounts of Chemical Research Open access 12 Jul 2008 2,663
26 Modern Synthetic Methods for Copper‐Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation Steven V. Ley, Andrew W. Thomas · Angewandte Chemie International Edition 11 Nov 2003 2,549
27 Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes David A. Nicewicz, David W. C. MacMillan · Science Open access 4 Sep 2008 2,490
28 Towards mild metal-catalyzed C–H bond activation Joanna Wencel‐Delord, Thomas Dröge, Fan Liu et al. · Chemical Society Reviews Review 2011 2,459
29 C–H bond activation enables the rapid construction and late-stage diversification of functional molecules Joanna Wencel‐Delord, Frank Glorius · Nature Chemistry 23 Apr 2013 2,406
30 Recent advances in the transition metal-catalyzed twofold oxidative C–H bond activation strategy for C–C and C–N bond formation Seung Hwan Cho, Ji Young Kim, Jaesung Kwak et al. · Chemical Society Reviews ReviewOpen access 2011 2,361
31 3d Transition Metals for C–H Activation Parthasarathy Gandeepan, Thomas Müller, Daniel Zell et al. · Chemical Reviews ReviewOpen access 27 Nov 2018 2,346
32 Recent advances in homogeneous nickel catalysis Sarah Z. Tasker, Eric A. Standley, Timothy F. Jamison · Nature Open access 13 May 2014 2,334
33 Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion Huw M. L. Davies, James R. Manning · Nature Open access 2008 2,325
34 Catalytic Carbophilic Activation: Catalysis by Platinum and Gold π Acids Alois Fürstner, Paul Davies · Angewandte Chemie International Edition 11 Apr 2007 2,323
35 C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation Guoyong Song, Fen Wang, Xingwei Li · Chemical Society Reviews Review 2012 2,304
36 The merger of transition metal and photocatalysis Jack Twilton, Chi “Chip” Le, Patricia Zhang et al. · Nature Reviews Chemistry Review 5 Jul 2017 2,272
37 Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners Ranjan Jana, Tejas P. Pathak, Matthew S. Sigman · Chemical Reviews ReviewOpen access 14 Feb 2011 2,266
38 Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis? Leyre Marzo, Santosh K. Pagire, Oliver Reiser et al. · Angewandte Chemie International Edition 21 Feb 2018 2,199
39 Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications Yoonsu Park, Youyoung Kim, Sukbok Chang · Chemical Reviews Review 4 Jan 2017 2,177
40 C-H Bond Functionalization in Complex Organic Synthesis Kamil Godula, Dalibor Sameš · Science 6 Apr 2006 2,162
41 On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition‐Metal Complexes Eric M. Simmons, John F. Hartwig · Angewandte Chemie International Edition 5 Mar 2012 2,160
42 Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis Gwilherm Evano, Nicolas Blanchard, Mathieu Toumi · Chemical Reviews Review Aug 2008 2,142
43 Hydroamination: Direct Addition of Amines to Alkenes and Alkynes Thomas Ernst Müller, Kai C. Hultzsch, Miguel Yus et al. · Chemical Reviews Review 26 Aug 2008 2,102
44 Carbon−Carbon Coupling Reactions Catalyzed by Heterogeneous Palladium Catalysts Yin, Jürgen Liebscher · Chemical Reviews Review 21 Dec 2006 2,086
45 Palladium-Catalyzed Transformations of Alkyl C–H Bonds Jian Feng He, Masayuki Wasa, Kelvin S. L. Chan et al. · Chemical Reviews ReviewOpen access 2 Dec 2016 2,065
46 Cross‐Coupling Reactions Of Organoboranes: An Easy Way To Construct CC Bonds (Nobel Lecture) Akira Suzuki · Angewandte Chemie International Edition 25 May 2011 2,055
47 Biaryl Phosphane Ligands in Palladium‐Catalyzed Amination David S. Surry, Stephen L. Buchwald · Angewandte Chemie International Edition Open access 28 Jul 2008 2,014
48 Catalytic Functionalization of C(sp 2 )H and C(sp 3 )H Bonds by Using Bidentate Directing Groups Guy Rouquet, Naoto Chatani · Angewandte Chemie International Edition 17 Sep 2013 2,008
49 Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds Olafs Daugulis, Hien‐Quang Do, Dmitry Shabashov · Accounts of Chemical Research Open access 24 Jun 2009 1,986
50 Direct C−H Transformation via Iron Catalysis Chang‐Liang Sun, Bi‐Jie Li, Zhang‐Jie Shi · Chemical Reviews Review 4 Nov 2010 1,979

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.