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Catalytic C–H Functionalization Methods

Catalytic C–H Functionalization Methods is a research topic within Organic Chemistry. Science Explorer counts 50k research works in it since 1957. 27.7% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the transition-metal-catalyzed functionalization of carbon-hydrogen (C–H) bonds, enabling the formation of carbon-carbon bonds, arylation, and synthesis of heterocycles. The research also explores applications in drug synthesis and oxidative coupling reactions.

  • Transition Metal Catalysis
  • C–H Activation
  • Carbon–Carbon Bond Formation
  • Arylation
  • Heterocycles
  • Drug Synthesis
  • Oxidative Coupling
  • Directed C–H Functionalization
  • Metal-Catalyzed Reactions
  • Biaryl Molecules
Research works
50k
fractional, since 1957
In the world top 10%
14k
per year above
Top-10% rate
27.7%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
-7%
the tick is no change

Which countries lead Catalytic C–H Functionalization Methods research?

By volume, China and India publish the most (4.7k and 1.2k works in 2022–2025).

By volume, 2022–2025

  1. 1 China 4.7k works
  2. 2 India 1.2k works
  3. 3 United States 806 works
  4. 4 Japan 446 works
  5. 5 Germany 378 works
  6. 6 France 238 works
  7. 7 Spain 176 works
  8. 8 Russia 174 works
  9. 9 United Kingdom 165 works
  10. 10 South Korea 154 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 55.2%India: 14.7%United States: 9.6%Japan: 5.3%6 others listed: 15.3%55%largest
China4,652 · 55.2%India1,240 · 14.7%United States806 · 9.6%Japan446 · 5.3%6 others listed1,286 · 15.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead Catalytic C–H Functionalization Methods research?

By volume in 2022–2025, Chinese Academy of Sciences publishes the most Catalytic C–H Functionalization Methods research, followed by Henan Normal University and Nankai University.

Who are the leading researchers in Catalytic C–H Functionalization Methods?

The most-cited researchers publishing on Catalytic C–H Functionalization Methods include Judith A. K. Howard, Wei Huang and Barry M. Trost.

  1. 1 Judith A. K. Howard United Kingdom 5.5k citations
  2. 2 Wei Huang China 5.5k citations
  3. 3 Barry M. Trost United States 3.8k citations
  4. 4 E. J. Corey United States 3.6k citations
  5. 5 Peter G. Jones Germany 3.6k citations
  6. 6 Stephen L. Buchwald United States 3.5k citations
  7. 7 David W. C. MacMillan United States 3.5k citations
  8. 8 William A. Goddard United States 3.2k citations
  9. 9 K. N. Houk United States 2.8k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Catalytic C–H Functionalization Methods research done?

The largest centres of Catalytic C–H Functionalization Methods research in 2022–2025 are Beijing (China), Shanghai (China), Hangzhou (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Xinxiang, Mülheim and Taizhou.

Largest cities, 2022–2025

  1. 1 Beijing China 482 works
  2. 2 Shanghai China 378 works
  3. 3 Hangzhou China 240 works
  4. 4 Nanjing China 238 works
  5. 5 Guangzhou China 223 works
  6. 6 Chengdu China 178 works
  7. 7 Tianjin China 161 works
  8. 8 Wuhan China 160 works
  9. 9 Hefei China 128 works
  10. 10 Xinxiang China 126 works

Where it is the local speciality

  1. XinxiangCN · 125.6 works48×
  2. MülheimDE · 21.2 works45×
  3. TaizhouCN · 29.5 works23×
  4. GhaziabadIN · 74.7 works17×
  5. QufuCN · 27.6 works16×
  6. TarragonaES · 25.2 works14×
← less than its size predictsmore →

Location quotient: how much more of its research is in Catalytic C–H Functionalization Methods than the world average.

See Catalytic C–H Functionalization Methods on the map

Where is the best place to study Catalytic C–H Functionalization Methods?

Among universities, judged by research, Henan Normal University, Southern University of Science and Technology and Nankai University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%60%mean 36.13%fractional works in this node (log) →share in the world top 10% →Henan Normal University: 116, 38.3%Southern University of Science and Technology: 50, 37.4%Nankai University: 100, 37.4%Hangzhou Normal University: 45, 33.8%University of Münster: 38, 53.9%University of Göttingen: 29, 52.1%Shaanxi Normal University: 27, 33.0%Nanjing Tech University: 54, 19.8%Zhengzhou University: 76, 28.7%Indian Institute of Technology Bombay: 44, 26.9%Henan Normal Univers…Southern University …Nankai UniversityHangzhou Normal Univ…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Henan Normal UniversityChina 76.138.3%64.0×116 +181.4%
2 Southern University of Science and TechnologyChina 73.037.4%10.4×50 +957.3%
3 Nankai UniversityChina 69.537.4%16.6×100 +87.4%
4 Hangzhou Normal UniversityChina 67.833.8%23.4×45 +188.2%
5 University of MünsterGermany 67.153.9%12.4×38 +29.4%
6 University of GöttingenGermany 66.152.1%11.9×29 +37.0%
7 Shaanxi Normal UniversityChina 64.333.0%10.6×27 +262.6%
8 Nanjing Tech UniversityChina 63.619.8%11.9×54 +315.4%
9 Zhengzhou UniversityChina 63.528.7%9.9×76 +91.2%
10 Indian Institute of Technology BombayIndia 63.326.9%11.2×44 +163.1%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Catalytic C–H Functionalization Methods research growing?

Output in 2018–2022 was 7% lower than in 2013–2017, peaking in 2015. The fastest-growing topics are Catalytic C–H Functionalization Methods.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.