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Topic · Organic Chemistry

Asymmetric Synthesis and Catalysis

Asymmetric Synthesis and Catalysis is a research topic within Organic Chemistry. Science Explorer counts 54k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers covers recent advances in asymmetric catalysis, including organocatalysis, enantioselective reactions, chiral catalysts, asymmetric synthesis, C-C bond formation, spirooxindoles, hydrogen bonding, transition metal catalysis, quaternary stereocenters, and cascade reactions.

  • Organocatalysis
  • Enantioselective Reactions
  • Chiral Catalysts
  • Asymmetric Synthesis
  • C-C Bond Formation
  • Spirooxindoles
  • Hydrogen Bonding
  • Transition Metal Catalysis
  • Quaternary Stereocenters
  • Cascade Reactions
Research works
54k
fractional, since 1950
In the world top 10%
5.3k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-13%
the tick is no change
Largest producer
China
47% of the 10 largest, 2022-now
Asymmetric Synthesis and Catalysis

Which countries lead Asymmetric Synthesis and Catalysis research?

By volume, China and the United States publish the most (1.2k and 277 works in 2022-now).

By volume, 2022-now

  1. 1 China 1.2k works
  2. 2 United States 277 works
  3. 3 India 275 works
  4. 4 Japan 214 works
  5. 5 Russia 132 works
  6. 6 Germany 126 works
  7. 7 France 101 works
  8. 8 Spain 81 works
  9. 9 United Kingdom 72 works
  10. 10 Italy 52 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 47.2%United States: 11.0%India: 10.9%Japan: 8.5%6 others listed: 22.4%47%largest
China1,190 · 47.2%United States277 · 11.0%India275 · 10.9%Japan214 · 8.5%6 others listed563 · 22.4%

Shares of the rows listed above, not of the whole node.

Which institutions lead Asymmetric Synthesis and Catalysis research?

By volume in 2022-now, Chinese Academy of Sciences publishes the most Asymmetric Synthesis and Catalysis research, followed by Russian Academy of Sciences and Centre National de la Recherche Scientifique.

By volume, 2022-now

  1. 1 Chinese Academy of SciencesChina 101 works
  2. 2 Russian Academy of SciencesRussia 74 works
  3. 3 Centre National de la Recherche ScientifiqueFrance 56 works
  4. 4 Sichuan UniversityChina 45 works
  5. 5 Nankai UniversityChina 37 works
  6. 6 Zhengzhou UniversityChina 28 works
  7. 7 Southern University of Science and TechnologyChina 27 works
  8. 8 Shanghai Jiao Tong UniversityChina 25 works
  9. 9 Henan Normal UniversityChina 24 works
  10. 10 Lanzhou UniversityChina 23 works

Who are the leading researchers in Asymmetric Synthesis and Catalysis?

The most-cited researchers publishing on Asymmetric Synthesis and Catalysis include Richard A. Gibbs, Jeremy Grimshaw and George M. Whitesides.

  1. 1 Richard A. Gibbs United States 292k citations
  2. 2 Jeremy Grimshaw Canada 281k citations
  3. 3 George M. Whitesides United States 267k citations
  4. 4 Wei Huang China 267k citations
  5. 5 Ben Zhong Tang China 261k citations
  6. 6 Stefan Grimme Germany 224k citations
  7. 7 Kai You Wang China 224k citations
  8. 8 George M. Sheldrick Germany 220k citations
  9. 9 John Anthony Pople United States 202k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Asymmetric Synthesis and Catalysis?

The most cited paper in Asymmetric Synthesis and Catalysis is "Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction" (Jwanro Hassan, Marc Sévignon, Christel Gozzi et al., 2002), with 3,659 citations. Next come "Asymmetric Transition Metal-Catalyzed Allylic Alkylations" (3,206) and "Natural Products as Sources of New Drugs over the Period 1981−2002" (3,095).

Most cited papers
#PaperReleasedCitations
1 Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction Jwanro Hassan, Marc Sévignon, Christel Gozzi et al. · Chemical Reviews Review 8 Mar 2002 3,659
2 Asymmetric Transition Metal-Catalyzed Allylic Alkylations Barry M. Trost, David L. Van Vranken · Chemical Reviews Review 1996 3,206
3 Natural Products as Sources of New Drugs over the Period 1981−2002 David J. Newman, Gordon M. L. Cragg, Kenneth M. Snader · Journal of Natural Products 12 Jun 2003 3,095
4 CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals Junichiro Yamaguchi, Atsushi D. Yamaguchi, Kenichiro Itami · Angewandte Chemie International Edition 6 Aug 2012 2,994
5 Proline-Catalyzed Direct Asymmetric Aldol Reactions Benjamin List, Richard Alan Lerner, Carlos F. Barbas · Journal of the American Chemical Society 26 Feb 2000 2,868
All 100 most cited papers, with filters and sorting

Where is Asymmetric Synthesis and Catalysis research done?

The largest centres of Asymmetric Synthesis and Catalysis research in 2022-now are Beijing (China), Shanghai (China), Chengdu (China) and Hangzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Xinxiang, Ufa and Sendai.

Largest cities, 2022-now

  1. 1 BeijingChina 146 works
  2. 2 ShanghaiChina 145 works
  3. 3 ChengduChina 78 works
  4. 4 HangzhouChina 54 works
  5. 5 TianjinChina 53 works
  6. 6 TokyoJapan 49 works
  7. 7 MoscowRussia 46 works
  8. 8 NanjingChina 39 works
  9. 9 ShenzhenChina 39 works
  10. 10 ChongqingChina 38 works

Where it is the local speciality

  1. XinxiangCN · 27.3 works33×
  2. UfaRU · 20.8 works19×
  3. SendaiJP · 21.1 works9.2×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Asymmetric Synthesis and Catalysis than the world average.

See Asymmetric Synthesis and Catalysis on the map

Where is the best place to study Asymmetric Synthesis and Catalysis?

Among universities, judged by research, Southern University of Science and Technology, Nankai University and ShanghaiTech University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 21.76%fractional works in this field (log) →share of work in the world top 10% →ShanghaiTech Univers…Southern University …Shanghai Jiao Tong U…Nankai University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Southern University of Science and TechnologyChina 75.027.8%20.1×27 +12.7%
2Nankai UniversityChina 69.825.1%21.5×37 +20.8%
3ShanghaiTech UniversityChina 63.442.6%18.1×8 +47.3%
4Shanghai Jiao Tong UniversityChina 57.626.2%3.4×25 +8.5%
5Henan Normal UniversityChina 57.119.7%47.7×24 +178.4%
6Sichuan UniversityChina 57.012.2%7.8×45 -6.9%
7University of Science and Technology of ChinaChina 53.322.2%6.4×19 +12.3%
8Lanzhou UniversityChina 47.811.0%13.1×23 +10.9%
9University of Chinese Academy of SciencesChina 47.421.2%5.5×23 -26.8%
10Zhengzhou UniversityChina 46.49.6%9.1×28 +7.0%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Asymmetric Synthesis and Catalysis, country by country

Is Asymmetric Synthesis and Catalysis research growing?

Output in 2022-2025 was 13% lower than in 2018-2021, peaking in 2010.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Asymmetric Synthesis and Catalysis as a percentage of every work published that year, 0.014% in 2024.

still counting0.050%0.10%0.15%Asymmetric Synthesis and Catalysis0.011% in 202519801990200020102020

Fractional works of Asymmetric Synthesis and Catalysis over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Asymmetric Synthesis and Catalysis9.6% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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