Chemical synthesis and alkaloids
Chemical synthesis and alkaloids is a research topic within Organic Chemistry. Science Explorer counts 32k research works in it since 1950. 16.4% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the chemistry, pharmacology, synthesis, and biological activities of Amaryllidaceae alkaloids such as galanthamine, narciclasine, and lycorine. These natural compounds show potential as anticancer agents, acetylcholinesterase inhibitors, and have medicinal significance. The research also explores their structure-activity relationships and potential therapeutic applications.
- Amaryllidaceae
- Alkaloids
- Galanthamine
- Narciclasine
- Lycorine
- Anticancer
- Acetylcholinesterase Inhibitors
- Synthesis
- Biological Activity
- Medicinal Potential
- Research works
- 32k fractional, since 1950
- In the world top 10%
- 5.3k per year above
- Top-10% rate
- 16.4% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- -7% the tick is no change
Which countries lead Chemical synthesis and alkaloids research?
By volume, China and the United States publish the most (622 and 529 works in 2022–2025).
By volume, 2022–2025
- 1 China 622 works
- 2 United States 529 works
- 3 India 360 works
- 4 Japan 133 works
- 5 United Kingdom 106 works
- 6 Germany 96 works
- 7 Brazil 91 works
- 8 Canada 82 works
- 9 Russia 75 works
- 10 France 71 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Chemical synthesis and alkaloids research?
By volume in 2022–2025, Chinese Academy of Sciences publishes the most Chemical synthesis and alkaloids research, followed by Lanzhou University and Chinese Academy of Medical Sciences & Peking Union Medical College.
By volume, 2022–2025
- 1 Chinese Academy of SciencesChina 20 works
- 2 Lanzhou UniversityChina 13 works
- 3 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 13 works
- 4 Johns Hopkins UniversityUnited States 12 works
- 5 Academy of Scientific and Innovative ResearchIndia 12 works
- 6 University of Chinese Academy of SciencesChina 10 works
- 7 University of North Carolina at Chapel HillUnited States 10 works
- 8 Botanical Survey of IndiaIndia 9 works
- 9 Centre National de la Recherche ScientifiqueFrance 9 works
- 10 University of OxfordUnited Kingdom 9 works
Who are the leading researchers in Chemical synthesis and alkaloids?
The most-cited researchers publishing on Chemical synthesis and alkaloids include Kevin D. Hyde, Barry M. Trost and E. J. Corey.
- 1 Kevin D. Hyde Thailand 4.8k citations
- 2 Barry M. Trost United States 3.8k citations
- 3 E. J. Corey United States 3.6k citations
- 4 Herbert C. Brown United States 3k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Chemical synthesis and alkaloids research done?
The largest centres of Chemical synthesis and alkaloids research in 2022–2025 are Beijing (China), Shanghai (China), Tokyo (Japan) and London (United Kingdom). Among places with at least 20 works in it, it is an unusually large share of all research in Kunming.
Largest cities, 2022–2025
Where it is the local speciality
- KunmingCN · 27.9 works4.2×
Location quotient: how much more of its research is in Chemical synthesis and alkaloids than the world average.
Where is the best place to study Chemical synthesis and alkaloids?
Among universities, judged by research, Academy of Scientific and Innovative Research, Johns Hopkins University and Imperial College London score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Academy of Scientific and Innovative ResearchIndia | 58.4 | 16.5% | 11.9× | 12 | +396.5% |
| 2 | Johns Hopkins UniversityUnited States | 49.0 | 54.5% | 3.5× | 12 | +10.3% |
| 3 | Imperial College LondonUnited Kingdom | 48.2 | 64.7% | 2.8× | 8 | +28.3% |
| 4 | Shenyang Pharmaceutical UniversityChina | 37.9 | 11.8% | 19.3× | 8 | +56.4% |
| 5 | Lanzhou UniversityChina | 37.1 | 16.6% | 7.0× | 13 | -54.9% |
| 6 | University of OxfordUnited Kingdom | 36.9 | 48.2% | 2.2× | 9 | -18.0% |
| 7 | China Pharmaceutical UniversityChina | 35.5 | 17.0% | 11.8× | 8 | -35.4% |
| 8 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 34.8 | 26.5% | 4.1× | 13 | -24.2% |
| 9 | University of North Carolina at Chapel HillUnited States | 33.2 | 27.8% | 1.9× | 10 | +153.3% |
| 10 | University of FloridaUnited States | 31.5 | 35.2% | 2.6× | 8 | +57.6% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Chemical synthesis and alkaloids research growing?
Output in 2018–2022 was 7% lower than in 2013–2017, peaking in 2006.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.