Topic · Chemical synthesis and alkaloids
Most cited papers in Chemical synthesis and alkaloids
What are the most cited papers in Chemical synthesis and alkaloids?
The most cited paper in Chemical synthesis and alkaloids is "Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize" (Carin C. C. Johansson Seechurn, Matthew O. Kitching, Thomas J. Colacot et al., 2012), with 3,024 citations. Next come "Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase" (2,475) and "The advent and development of organocatalysis" (2,407).
Showing 50 of 100 papers. Every paper with more than 644 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize Carin C. C. Johansson Seechurn, Matthew O. Kitching, Thomas J. Colacot et al. · Angewandte Chemie International Edition | 9 May 2012 | 3,024 |
| 2 | Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase Tatsuya Tamaoki, Hisayo Nomoto, ISAMI TAKAHASHI et al. · Biochemical and Biophysical Research Communications | Mar 1986 | 2,475 |
| 3 | The advent and development of organocatalysis David W. C. MacMillan · Nature | Sep 2008 | 2,407 |
| 4 | Amide bond formation: beyond the myth of coupling reagents Eric Valeur, Mark Bradley · Chemical Society Reviews | 4 Dec 2008 | 2,203 |
| 5 | Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis Gwilherm Evano, Nicolas Blanchard, Mathieu Toumi · Chemical Reviews | Aug 2008 | 2,142 |
| 6 | Cascade Reactions in Total Synthesis Kyriacos Costa Nicolaou, David J. Edmonds, Paul G. Bulger · Angewandte Chemie International Edition | 30 Oct 2006 | 2,093 |
| 7 | Cross‐Coupling Reactions Of Organoboranes: An Easy Way To Construct CC Bonds (Nobel Lecture) Akira Suzuki · Angewandte Chemie International Edition | 25 May 2011 | 2,055 |
| 8 | Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone? Dean G. Brown, Jonas Boström · Journal of Medicinal Chemistry | 16 Nov 2015 | 2,040 |
| 9 | A Historical Overview of Natural Products in Drug Discovery Daniel Anthony Dias, Sylvia Urban, Ute Roessner · Metabolites | 16 Apr 2012 | 1,984 |
| 10 | Cholinesterase inhibitors for Alzheimer's disease Jacqueline Susan Birks · Cochrane Database of Systematic Reviews | 19 Jan 2006 | 1,886 |
| 11 | The Diels-Alder Reaction in Total Synthesis K. C. Nicolaou, Scott A. Snyder, Tamsyn Montagnon et al. · Angewandte Chemie International Edition | 17 May 2002 | 1,844 |
| 12 | Psychedelics David E. Nichols · Pharmacological Reviews | 3 Feb 2016 | 1,806 |
| 13 | Endophytes: a rich source of functional metabolites (1987 to 2000) Ren Xiang Tan, W. X. Zou · Natural Product Reports | 2001 | 1,770 |
| 14 | Recent applications of the Suzuki–Miyaura cross-coupling reaction in organic synthesis Sambasivarao Kotha, Kakali Lahiri, Dhurke Kashinath · Tetrahedron | Nov 2002 | 1,703 |
| 15 | Organocatalytic cascade reactions as a new tool in total synthesis Christoph Grondal, Matthieu Jeanty, Dieter Enders · Nature Chemistry | 19 Feb 2010 | 1,583 |
| 16 | Acetylenic Coupling: A Powerful Tool in Molecular Construction Peter Siemsen, R. C. Livingston, François Diederich · Angewandte Chemie International Edition | 4 Aug 2000 | 1,514 |
| 17 | Metal‐Catalyzed Enantioselective Allylation in Asymmetric Synthesis Zhan Ling Lu, Shengming Ma · Angewandte Chemie International Edition | 29 Oct 2007 | 1,507 |
| 18 | Recent Applications of Palladium‐Catalyzed Coupling Reactions in the Pharmaceutical, Agrochemical, and Fine Chemical Industries C. Torborg, Matthias Beller · Advanced Synthesis & Catalysis | Dec 2009 | 1,483 |
| 19 | The Asymmetric Intramolecular Heck Reaction in Natural Product Total Synthesis Amy B. Dounay, Larry E. Overman · Chemical Reviews | 8 Jul 2003 | 1,479 |
| 20 | Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior Marina R. Picciotto, Michael J. Higley, Yann S. Mineur · Neuron | Oct 2012 | 1,456 |
| 21 | Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole Alkaloids Christiane Marti, Erick M. Carreira · European Journal of Organic Chemistry | Jun 2003 | 1,454 |
| 22 | Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective Michaël Wink · Phytochemistry | 16 Jul 2003 | 1,450 |
| 23 | Isolation and Synthesis of Biologically Active Carbazole Alkaloids Hans‐Joachim Knölker, Kethiri R. Reddy · Chemical Reviews | Nov 2002 | 1,404 |
| 24 | Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol Stephen J. Peroutka, Solomon H. Snyder · Molecular Pharmacology | Nov 1979 | 1,361 |
| 25 | The Raison d'Être of Secondary Plant Substances G. Fraenkel · Science | 29 May 1959 | 1,286 |
| 26 | Human hallucinogen research: guidelines for safety MW Johnson, WA Richards, R. R. Griffiths · Journal of Psychopharmacology | 30 May 2008 | 1,223 |
| 27 | Psychedelics Promote Structural and Functional Neural Plasticity Calvin Ly, Alexandra C. Greb, Lindsay P. Cameron et al. · Cell Reports | Jun 2018 | 1,215 |
| 28 | Chelerythrine is a potent and specific inhibitor of protein kinase C Jean‐Marc Herbert, Jean‐Michel Augereau, J. Gleye et al. · Biochemical and Biophysical Research Communications | Nov 1990 | 1,210 |
| 29 | Recent Advances in Asymmetric Organocatalytic 1,4‐Conjugate Additions Svetlana B. Tsogoeva · European Journal of Organic Chemistry | Mar 2007 | 1,150 |
| 30 | Chemistry and Biology of the Tetrahydroisoquinoline Antitumor Antibiotics Jack D. Scott, Robert M. Williams · Chemical Reviews | 18 Apr 2002 | 1,148 |
| 31 | Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease Gabriella Marucci, Michela Buccioni, Diego Dal Ben et al. · Neuropharmacology | 6 Oct 2020 | 1,126 |
| 32 | Highly Active Palladium Catalysts for Suzuki Coupling Reactions John P. Wolfe, Robert A. Singer, Bryant H. Yang et al. · Journal of the American Chemical Society | Oct 1999 | 1,126 |
| 33 | THE ASCENDING CHOLINERGIC RETICULAR SYSTEM: NEOCORTICAL, OLFACTORY AND SUBCORTICAL PROJECTIONS C. C. D. Shute, Peter Raymond Lewis · Brain | 1967 | 1,119 |
| 34 | Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C Eiji Kobayashi, Hirofumi Nakano, Makoto Morimoto et al. · Biochemical and Biophysical Research Communications | Mar 1989 | 1,117 |
| 35 | Stereospecific Binding of the Potent Narcotic Analgesic [ 3 H]Etorphine to Rat-Brain Homogenate Eric J. Simon, Jacob M. Hiller, Irit Edelman · Proceedings of the National Academy of Sciences | Jul 1973 | 1,069 |
| 36 | Casarett and Doull's toxicology: The basic science of poisons John Pickrell · Toxicology Letters | Apr 1996 | 1,062 |
| 37 | Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions Masahiro Terada · Chemical Communications | 2008 | 1,043 |
| 38 | STEREOCHEMISTRY AND THE MECHANISM OF ENZYMATIC REACTIONS Daniel E. Koshland · Biological reviews/Biological reviews of the Cambridge Philosophical Society | Nov 1953 | 1,013 |
| 39 | Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels Matthias Schramm, G. Thomas, Robertson Towart et al. · Nature | Jun 1983 | 1,007 |
| 40 | Biology and chemistry of endophytes Huawei Zhang, Yong Song, Ren Xiang Tan · Natural Product Reports | 2006 | 997 |
| 41 | Chemistry and Biology of the Enediyne Anticancer Antibiotics K. C. Nicolaou, Wei‐Min Dai · Angewandte Chemie International Edition in English | Nov 1991 | 988 |
| 42 | Catalytic cross-coupling reactions in biaryl synthesis Stephen P. Stanforth · Tetrahedron | 1998 | 957 |
| 43 | Synthesis of Biaryls via Catalytic Decarboxylative Coupling Lukas J. Gooßen, Guo‐Jun Deng, Laura M. Levy · Science | 3 Aug 2006 | 953 |
| 44 | K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases Hiroshi Kase, Kazuyuki Iwahashi, Satoshi Nakanishi et al. · Biochemical and Biophysical Research Communications | 1987 | 944 |
| 45 | SIXTH GADDUM MEMORIAL LECTURE NATIONAL INSTITUTE FOR MEDICAL RESEARCH, MILL HILL, JANUARY 1977 S Z Langer · British Journal of Pharmacology | Aug 1977 | 944 |
| 46 | Claisen Rearrangement over the Past Nine Decades Ana M. Martı́n Castro · Chemical Reviews | 23 Apr 2004 | 940 |
| 47 | Stereochemical Control in Organic Synthesis Using Silicon-Containing Compounds Ian Fleming, Asunción Barbero, David J. Walter · Chemical Reviews | Oct 1997 | 938 |
| 48 | Recent developments in indole ring synthesis—methodology and applications Gordon W. Gribble · Journal of the Chemical Society Perkin Transactions 1 | 2000 | 933 |
| 49 | A 5-month, randomized, placebo-controlled trial of galantamine in AD Pierre N. Tariot, Paul R. Solomon, Julie Morris et al. · Neurology | 27 Jun 2000 | 926 |
| 50 | Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness Katherine A. MacLean, Matthew W. Johnson, Roland R. Griffiths · Journal of Psychopharmacology | 28 Sep 2011 | 924 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.