Topic · Chemical Reactions and Isotopes
Most cited papers in Chemical Reactions and Isotopes
What are the most cited papers in Chemical Reactions and Isotopes?
The most cited paper in Chemical Reactions and Isotopes is "A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter" (George A. Bray, 1960), with 7,511 citations. Next come "THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE" (6,512) and "Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues" (6,083).
Showing 50 of 100 papers. Every paper with more than 550 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter George A. Bray · Analytical Biochemistry | Dec 1960 | 7,511 |
| 2 | THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE Richard C. Graham, Morris J. Karnovsky · Journal of Histochemistry & Cytochemistry | Apr 1966 | 6,512 |
| 3 | Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues Frank Tietze · Analytical Biochemistry | Mar 1969 | 6,083 |
| 4 | How a century of ammonia synthesis changed the world Jan Willem Erisman, Mark A. Sutton, James N. Galloway et al. · Nature Geoscience | 28 Sep 2008 | 4,691 |
| 5 | Culture Medium for Enterobacteria Frederick C. Neidhardt, Philip L. Bloch, David F. Smith · Journal of Bacteriology | Sep 1974 | 3,062 |
| 6 | Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode Barnett Rosenberg, Loretta Van Camp, Thomas Krigas · Nature | Feb 1965 | 3,054 |
| 7 | Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics | Jul 1994 | 2,793 |
| 8 | Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection Bruce N. Ames, William E. Durston, Edith F. Yamasaki et al. · Proceedings of the National Academy of Sciences | Aug 1973 | 2,296 |
| 9 | Inactivation of the DNA-Repair Gene MGMT and the Clinical Response of Gliomas to Alkylating Agents Manel Esteller, Jesús García‐Foncillas, Esther Andion et al. · New England Journal of Medicine | 9 Nov 2000 | 2,251 |
| 10 | Stereological Principles for Morphometry in Electron Microscopic Cytology Ewald R. Weibel · International review of cytology | 1969 | 1,957 |
| 11 | Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture Daniel W. Nebert, Harry V. Gelboin · Journal of Biological Chemistry | Dec 1968 | 1,683 |
| 12 | A synthetic method for formyl→ethynyl conversion (RCHO→RCCH or RCCR′) Elias James Corey, P.L. Fuchs · Tetrahedron Letters | 1972 | 1,578 |
| 13 | An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens Bruce N. Ames, Frank D. Lee, William E. Durston · Proceedings of the National Academy of Sciences | Mar 1973 | 1,547 |
| 14 | Autoradiographic Study of Cell Migration during Histogenesis of Cerebral Cortex in the Mouse Jay B. Angevine, Richard L. Sidman · Nature | Nov 1961 | 1,537 |
| 15 | RESPIRATORY ENZYMES IN OXIDATIVE PHOSPHORYLATION Britton Chance, Gene R. Williams · Journal of Biological Chemistry | Nov 1955 | 1,480 |
| 16 | STROMAL CELLS RESPONSIBLE FOR TRANSFERRING THE MICROENVIRONMENT OF THE HEMOPOIETIC TISSUES A. J. Friedenstein, Ruben K. Chailakhyan, Nataly V. Latsinik et al. · Transplantation | Apr 1974 | 1,436 |
| 17 | Hepatic Triphosphopyridine Nucleotide-Cytochrome c Reductase: Isolation, Characterization, and Kinetic Studies Alvah H. Phillips, ROBERT G. LANGDON · Journal of Biological Chemistry | Aug 1962 | 1,433 |
| 18 | Optimal conditions for mutagenesis by N-methyl-N′-nitro-N-nitrosoguanidine in escherichia coli K12 Edward A. Adelberg, Morton Mandel, Grace Chein Ching Chen · Biochemical and Biophysical Research Communications | Mar 1965 | 1,380 |
| 19 | Cellular Control of the Synthesis and Activity of the Bacterial Luminescent System Kenneth H. Nealson, Terry Platt, John Woodland Hastings · Journal of Bacteriology | Oct 1970 | 1,310 |
| 20 | The hydrogen hypothesis for the first eukaryote William Martin, Miklós Müller · Nature | Mar 1998 | 1,297 |
| 21 | Electrochemically induced nuclear fusion of deuterium M. Fleischmann, Stanley Pons · Journal of Electroanalytical Chemistry | Apr 1989 | 1,292 |
| 22 | Unique Biosynthesis by Kidney of a Biologically Active Vitamin D Metabolite David R. Fraser, Egon Hynek Kodicek · Nature | Nov 1970 | 1,289 |
| 23 | Molecular Imaging with PET Simon Mensah Ametamey, Michael Honer, Pius August Schubiger · Chemical Reviews | 22 Apr 2008 | 1,274 |
| 24 | Nitrosylation Jonathan S. Stamler, Santiago Lamas, Ferric C. Fang · Cell | Sep 2001 | 1,263 |
| 25 | DETERMINATION OF NUCLEIC ACIDS IN ANIMAL TISSUES Giovanni Ceriotti · Journal of Biological Chemistry | May 1955 | 1,248 |
| 26 | Catalytic Synthesis of Ammonia—A “Never‐Ending Story”? Robert Schlögl · Angewandte Chemie International Edition | 8 May 2003 | 1,200 |
| 27 | Sonochemistry: Science and Engineering L. H. Thompson, L. K. Doraiswamy · Industrial & Engineering Chemistry Research | 9 Mar 1999 | 1,186 |
| 28 | Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution Mark J. Shackleton, Elsa Quintana, Eric R. Fearon et al. · Cell | Sep 2009 | 1,172 |
| 29 | Host-Derived Nitrate Boosts Growth of E. coli in the Inflamed Gut Sebastian Winter, Maria G. Winter, Mariana Noyma Xavier et al. · Science | 7 Feb 2013 | 1,045 |
| 30 | STEREOCHEMISTRY AND THE MECHANISM OF ENZYMATIC REACTIONS Daniel E. Koshland · Biological reviews/Biological reviews of the Cambridge Philosophical Society | Nov 1953 | 1,013 |
| 31 | Direct Nuclear Reactions G.R. Satchler, G. F. Bertsch · Physics Today | Feb 1984 | 983 |
| 32 | Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Christoph Sachse, Jürgen Brockmöller, Steffen Bauer et al. · PubMed | Feb 1997 | 978 |
| 33 | Biosurfactants: potential applications in medicine Lígia R. Rodrigues, Ibrahim Mohamed Banat, José António Teixeira et al. · Journal of Antimicrobial Chemotherapy | 9 Feb 2006 | 932 |
| 34 | Reaction Rates of Isotopic Molecules VERNON J. JUN. SHINER · BioScience | Jul 1981 | 913 |
| 35 | Use of the liquid scintillation spectrometer for determining adenosine triphosphate by the luciferase enzyme Philip E. Stanley, S. G. Williams · Analytical Biochemistry | Jun 1969 | 907 |
| 36 | Microsomal Triphosphopyridine Nucleotide-Cytochrome c Reductase of Liver Charles H. Williams, Henry Kamin · Journal of Biological Chemistry | Feb 1962 | 905 |
| 37 | Negative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small-cell lung cancer Lisa Derosa, Matthew David Hellmann, Marco Spaziano et al. · Annals of Oncology | 29 Mar 2018 | 900 |
| 38 | The single cell gel electrophoresis assay (comet assay): A European review Valerie J. McKelvey‐Martin, M.H.L. Green, Peter Schmezer et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis | Jul 1993 | 895 |
| 39 | Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity Asim Kumar Debnath, Rosa L. Lopez de Compadre, Gargi Debnath et al. · Journal of Medicinal Chemistry | Feb 1991 | 893 |
| 40 | Applications of Deuterium in Medicinal Chemistry Tracey Pirali, M. Teresa Serafini, Sarah Cargnin et al. · Journal of Medicinal Chemistry | 14 Jan 2019 | 868 |
| 41 | Radioactive Labeling of Proteins in Vitro Robert H. Rice, Gary E. Means · Journal of Biological Chemistry | Feb 1971 | 840 |
| 42 | Distinct Mediating Systems for the Transport of Neutral Amino Acids by the Ehrlich Cell Dale L. Oxender, Halvor N. Christensen · Journal of Biological Chemistry | Nov 1963 | 840 |
| 43 | A principle for counting tissue structures on random sections Ewald R. Weibel, Domingo M. Gómez · Journal of Applied Physiology | Mar 1962 | 837 |
| 44 | THE ORGANIZATION AND DUPLICATION OF CHROMOSOMES AS REVEALED BY AUTORADIOGRAPHIC STUDIES USING TRITIUM-LABELED THYMIDINEE James Herbert Taylor, Philip S. Woods, Walter L. Hughes · Proceedings of the National Academy of Sciences | 15 Jan 1957 | 830 |
| 45 | Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization Edward D. Levin, Francis Joseph McClernon, Amir H. Rezvani · Psychopharmacology | 11 Oct 2005 | 821 |
| 46 | Deuterium‐ and Tritium‐Labelled Compounds: Applications in the Life Sciences Jens Atzrodt, Volker Derdau, William J. Kerr et al. · Angewandte Chemie International Edition | 17 Aug 2017 | 820 |
| 47 | Human Extrahepatic Cytochromes P450: Function in Xenobiotic Metabolism and Tissue-Selective Chemical Toxicity in the Respiratory and Gastrointestinal Tracts Xinxin Ding, Laurence S. Kaminsky · The Annual Review of Pharmacology and Toxicology | 22 Jan 2003 | 820 |
| 48 | Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone Pamela A. Williams, José Cosme, Dijana Matak‐Vinković et al. · Science | 15 Jul 2004 | 811 |
| 49 | THE QUANTITATIVE HISTOCHEMISTRY OF BRAIN Oliver H. Lowry, Nira R. Roberts, Meiling Wu et al. · Journal of Biological Chemistry | Mar 1954 | 811 |
| 50 | Cancer--A Biological Approach: I. The Processes Of Control. II. The Significance of Somatic Mutation Michael W. M. Burnet · BMJ | 6 Apr 1957 | 809 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.