Topic · Circadian rhythm and melatonin
Most cited papers in Circadian rhythm and melatonin
What are the most cited papers in Circadian rhythm and melatonin?
The most cited paper in Circadian rhythm and melatonin is "Protective and Damaging Effects of Stress Mediators" (Bruce S. McEwen, 1998), with 6,716 citations. Next come "Hallmarks of aging: An expanding universe" (6,477) and "The structure of the nervous system of the nematode Caenorhabditis elegans" (5,884).
Showing 50 of 99 papers. Every paper with more than 1,475 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Protective and Damaging Effects of Stress Mediators Bruce S. McEwen · New England Journal of Medicine | 15 Jan 1998 | 6,716 |
| 2 | Hallmarks of aging: An expanding universe Carlos López-Otı́n, Marı́a A. Blasco, Linda Partridge et al. · Cell | 2023 | 6,477 |
| 3 | The structure of the nervous system of the nematode Caenorhabditis elegans JG White, Eileen Southgate, J. Nichol Thomson et al. · Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 12 Nov 1986 | 5,884 |
| 4 | Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior Takeshi Sakurai et al. · Cell | Feb 1998 | 5,551 |
| 5 | Inflamm‐aging: An Evolutionary Perspective on Immunosenescence Claudio Franceschi, Massimiliano Bonafè, Silvana Valensin et al. · Annals of the New York Academy of Sciences | Jun 2000 | 5,391 |
| 6 | Coordination of circadian timing in mammals Steven M. Reppert, David R. Weaver · Nature | Aug 2002 | 4,422 |
| 7 | Rapamycin fed late in life extends lifespan in genetically heterogeneous mice David E. Harrison, Randy Strong, Zelton Dave Sharp et al. · Nature | Jul 2009 | 3,836 |
| 8 | Epidemiology of insomnia: what we know and what we still need to learn Maurice Moyses Ohayon · Sleep Medicine Reviews | May 2002 | 3,775 |
| 9 | The inflammatory reflex Kevin J. Tracey · Nature | Dec 2002 | 3,734 |
| 10 | Phototransduction by Retinal Ganglion Cells That Set the Circadian Clock David M. Berson, Felice A. Dunn, Motoharu Takao · Science | 8 Feb 2002 | 3,689 |
| 11 | Post-embryonic cell lineages of the nematode, Caenorhabditis elegans J.E. Sulston, H. Robert Horvitz · Developmental Biology | Mar 1977 | 3,621 |
| 12 | Solid-State Light Sources Getting Smart E. Fred Schubert, Jong Kyu Kim · Science | 26 May 2005 | 3,533 |
| 13 | Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems Christelle Peyron, Devin K. Tighe, Anthony N. van den Pol et al. · Journal of Neuroscience | Dec 1998 | 3,495 |
| 14 | Oxidative Stress, Caloric Restriction, and Aging Rajindar S. Sohal, Richard H. Weindruch · Science | 5 Jul 1996 | 3,152 |
| 15 | Extending Healthy Life Span—From Yeast to Humans Luigi Fontana, Linda Partridge, Valter Daniel Longo · Science | 15 Apr 2010 | 3,087 |
| 16 | Mortality risk attributable to high and low ambient temperature: a multicountry observational study Antonio Gasparrini et al. · The Lancet | 21 May 2015 | 3,009 |
| 17 | Molecular Bases for Circadian Clocks Jay Dunlap · Cell | 1999 | 2,943 |
| 18 | Hypothalamic regulation of sleep and circadian rhythms Clifford B. Saper, Thomas E. Scammell, Jun Lu · Nature | 26 Oct 2005 | 2,833 |
| 19 | Insomnia as a predictor of depression: A meta-analytic evaluation of longitudinal epidemiological studies Chiara Baglioni, Gemma Battagliese, Bernd Feige et al. · Journal of Affective Disorders | 7 Feb 2011 | 2,810 |
| 20 | Transcriptional architecture of the mammalian circadian clock Joseph S. Takahashi · Nature Reviews Genetics | 19 Dec 2016 | 2,792 |
| 21 | The genetics of ageing Cynthia J. Kenyon · Nature | 23 Mar 2010 | 2,774 |
| 22 | Melanopsin-Containing Retinal Ganglion Cells: Architecture, Projections, and Intrinsic Photosensitivity Samer S Hattar, H.–W. Liao, Motoharu Takao et al. · Science | 8 Feb 2002 | 2,774 |
| 23 | Channelrhodopsin-2, a directly light-gated cation-selective membrane channel Georg Nagel, Tanjef Szellas, Wolfram Huhn et al. · Proceedings of the National Academy of Sciences | 13 Nov 2003 | 2,743 |
| 24 | Life between Clocks: Daily Temporal Patterns of Human Chronotypes Till Roenneberg, Anna Wirz‐Justice, Martha W. Merrow · Journal of Biological Rhythms | Feb 2003 | 2,716 |
| 25 | Chromatin Structure: A Repeating Unit of Histones and DNA Roger D. Kornberg · Science | 24 May 1974 | 2,679 |
| 26 | Social Jetlag: Misalignment of Biological and Social Time Marc Wittmann, Jenny Dinich, Martha W. Merrow et al. · Chronobiology International | 2006 | 2,649 |
| 27 | The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs Yi Zhun Zhu et al. · Aging Cell | 9 Mar 2015 | 2,539 |
| 28 | Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice Fred William Turek, Corinne E. Joshu, Akira Kohsaka et al. · Science | 21 Apr 2005 | 2,510 |
| 29 | The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks Charna Dibner, Ueli Schibler, Urs Albrecht · Annual Review of Physiology | 11 Feb 2010 | 2,463 |
| 30 | A circadian gene expression atlas in mammals: Implications for biology and medicine Ray Zhang, Nicholas F. Lahens, Heather I. Ballance et al. · Proceedings of the National Academy of Sciences | 27 Oct 2014 | 2,447 |
| 31 | Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus Francesca Damiola, Nguyet Le Minh, Nicolas Preitner et al. · Genes & Development | Dec 2000 | 2,428 |
| 32 | PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues Seung Hee Yoo, Shin Yamazaki, Phillip L. Lowrey et al. · Proceedings of the National Academy of Sciences | 12 Feb 2004 | 2,399 |
| 33 | Seasonal Affective Disorder Norman E. Rosenthal · Archives of General Psychiatry | 1984 | 2,386 |
| 34 | Adverse metabolic and cardiovascular consequences of circadian misalignment Frank A. J. L. Scheer, Michael F. Hilton, Christos Socrates Mantzoros et al. · Proceedings of the National Academy of Sciences | 2 Mar 2009 | 2,359 |
| 35 | Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock Satchidananda Panda, Marina P. Antoch, Brooke H. Miller et al. · Cell | May 2002 | 2,333 |
| 36 | Clock Mutants of Drosophila melanogaster Ronald J. Konopka, Seymour Benzer · Proceedings of the National Academy of Sciences | Sep 1971 | 2,317 |
| 37 | Central and Peripheral Circadian Clocks in Mammals Jennifer A. Mohawk, Carla B. Green, Joseph S. Takahashi · Annual Review of Neuroscience | 20 May 2012 | 2,312 |
| 38 | daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans Koutarou D. Kimura, Heidi A. Tissenbaum, Yanxia Liu et al. · Science | 15 Aug 1997 | 2,298 |
| 39 | Epidemiology and Risk Factors of Urothelial Bladder Cancer Maximilian Burger, James W.F. Catto, Guido M. Dalbagni et al. · European Urology | 25 Jul 2012 | 2,220 |
| 40 | Stress-induced immune dysfunction: implications for health Ronald Glaser, Janice K. Kiecolt‐Glaser · Nature reviews. Immunology | Mar 2005 | 2,219 |
| 41 | Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions* RUSSEL J. REITER · Endocrine Reviews | May 1991 | 2,206 |
| 42 | The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator Nicolas Preitner, Francesca Damiola, Luis Lopez‐Molina et al. · Cell | Jul 2002 | 2,184 |
| 43 | A functional analysis of circadian pacemakers in nocturnal rodents Colin S. Pittendrigh, Serge Daan · Journal of Comparative Physiology A | Oct 1976 | 2,143 |
| 44 | Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat Robert Y. Moore, Victor B. Eichler · Brain Research | Jul 1972 | 2,136 |
| 45 | Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions Friedrich K. Stephan, Irving H. Zucker · Proceedings of the National Academy of Sciences | Jun 1972 | 2,043 |
| 46 | Role of the CLOCK Protein in the Mammalian Circadian Mechanism Nicholas Gekakis, David Staknis, Hubert B. Nguyen et al. · Science | 5 Jun 1998 | 2,035 |
| 47 | A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells Aurélio Balsalobre, Francesca Damiola, Ueli Schibler · Cell | Jun 1998 | 2,022 |
| 48 | Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet Megumi Hatori, Christopher Vollmers, Amir Zarrinpar et al. · Cell Metabolism | 16 May 2012 | 2,014 |
| 49 | Regulation of antioxidant enzymes: a significant role for melatonin Carmen Rodrı́guez, Juan Carlos Mayo, Rosa María Sainz et al. · Journal of Pineal Research | 11 Dec 2003 | 2,004 |
| 50 | Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor George C. Brainard, John P. Hanifin, Jeffrey M. Greeson et al. · Journal of Neuroscience | 15 Aug 2001 | 1,949 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.