Most cited papers in Connective Tissue Growth Factor Research
What are the most cited papers in Connective Tissue Growth Factor Research?
The most cited paper in Connective Tissue Growth Factor Research is "Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma" (Robert John Motzer, Thomas E. Hutson, Piotr Tomczak et al., 2007), with 5,801 citations. Next come "Transforming Growth Factor β in Tissue Fibrosis" (3,093) and "A multigenic program mediating breast cancer metastasis to bone" (2,627).
Showing 50 of 100 papers. Every paper with more than 574 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma Robert John Motzer, Thomas E. Hutson, Piotr Tomczak et al. · New England Journal of Medicine | 10 Jan 2007 | 5,801 |
| 2 | Transforming Growth Factor β in Tissue Fibrosis Franklin H. Epstein, Wayne A. Border, Nancy A. Noble · New England Journal of Medicine | 10 Nov 1994 | 3,093 |
| 3 | A multigenic program mediating breast cancer metastasis to bone Yibin Kang, Peter M. Siegel, Weiping Shu et al. · Cancer Cell | Jun 2003 | 2,627 |
| 4 | Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma Robert John Motzer et al. · New England Journal of Medicine | 16 Feb 2019 | 2,590 |
| 5 | Role of Transforming Growth Factor β in Human Disease Gerard C. Blobe, William P. Schiemann, Harvey F. Lodish · New England Journal of Medicine | 4 May 2000 | 2,439 |
| 6 | TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders Joan Massagué, Stacy Wister Blain, Roger S. Lo · Cell | Oct 2000 | 2,384 |
| 7 | TGF‐β signaling and the fibrotic response Andrew Leask, David Abraham · The FASEB Journal | 29 Apr 2004 | 2,304 |
| 8 | Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial Bernard J. Escudier, Anna Pluzanska, P. Koralewski et al. · The Lancet | Dec 2007 | 2,234 |
| 9 | Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma Robert John Motzer, Thomas E. Hutson, Piotr Tomczak et al. · Journal of Clinical Oncology | Jun 2009 | 2,196 |
| 10 | The biology of platelet-derived growth factor Russell Ross, Elaine W. Raines, Daniel F. Bowen‐Pope · Cell | Jul 1986 | 2,021 |
| 11 | The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. David M. Kingsley · Genes & Development | 1994 | 1,941 |
| 12 | Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma Robert John Motzer et al. · New England Journal of Medicine | 21 Aug 2013 | 1,936 |
| 13 | Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma Robert John Motzer et al. · New England Journal of Medicine | 13 Feb 2021 | 1,811 |
| 14 | TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation Guiqian Chen, Chuxia Deng, Yiping Li · International Journal of Biological Sciences | 2012 | 1,759 |
| 15 | Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases Thomas A. Wynn · Journal of Clinical Investigation | Mar 2007 | 1,474 |
| 16 | Inflammation in osteoarthritis Mary B. Goldring, Miguel Otero · Current Opinion in Rheumatology | 23 Jul 2011 | 1,473 |
| 17 | Fibrosis — A Common Pathway to Organ Injury and Failure Don C. Rockey, Phillip Darwin Bell, Joseph A. Hill · New England Journal of Medicine | 18 Mar 2015 | 1,438 |
| 18 | Scleroderma Armando Gabrielli, Enrico Vittorio Avvedimento, Thomas M. Krieg · New England Journal of Medicine | 6 May 2009 | 1,391 |
| 19 | Circular RNA circMTO1 acts as the sponge of microRNA‐9 to suppress hepatocellular carcinoma progression Dan Han, Jiangxue Li, Huamin Wang et al. · Hepatology | 18 May 2017 | 1,349 |
| 20 | Transforming growth factor–β in tissue fibrosis Nikolaos G. Frangogiannis · The Journal of Experimental Medicine | 25 Dec 2019 | 1,322 |
| 21 | TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology Masato Morikawa, Rik Derynck, Kohei Miyazono · Cold Spring Harbor Perspectives in Biology | May 2016 | 1,313 |
| 22 | Signal Transduction by the TGF-β Superfamily Liliana Attisano, Jeffrey L. Wrana · Science | 31 May 2002 | 1,276 |
| 23 | New insights into TGF-β/Smad signaling in tissue fibrosis He-He Hu, Dan‐Qian Chen, Yanni Wang et al. · Chemico-Biological Interactions | 11 Jul 2018 | 1,209 |
| 24 | Transforming Growth Factor-β: Biological Function and Chemical Structure Michael B. Sporn, Anita B. Roberts, Lalage M. Wakefield et al. · Science | Aug 1986 | 1,187 |
| 25 | TGF-β signaling in fibrosis Anna Biernacka, Marcin Dobaczewski, Nikolaos G. Frangogiannis · Growth Factors | 11 Jul 2011 | 1,186 |
| 26 | Systemic sclerosis: a prototypic multisystem fibrotic disorder John Varga, David Abraham · Journal of Clinical Investigation | Mar 2007 | 1,166 |
| 27 | Pathologic observations in systemic sclerosis (scleroderma) William D’Angelo, James F. Fries, Alfonse T. Masi et al. · The American Journal of Medicine | Mar 1969 | 1,123 |
| 28 | Non-Smad TGF-β signals Aristidis Moustakas, Carl‐Henrik Heldin · Journal of Cell Science | 15 Aug 2005 | 1,083 |
| 29 | The control of chondrogenesis Mary B. Goldring, Kaneyuki Tsuchimochi, Kosei Ijiri · Journal of Cellular Biochemistry | 2005 | 1,068 |
| 30 | Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients András Szász, András Lánczky, Ádám M. Nagy et al. · Oncotarget | 30 Jun 2016 | 1,067 |
| 31 | Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster Michael Dews, Asal Homayouni, Duonan Yu et al. · Nature Genetics | 30 Jul 2006 | 1,052 |
| 32 | Kruppel-Like Factor 15 Modulates Renal Interstitial Fibrosis by ERK/MAPK and JNK/MAPK Pathways Regulation Xiang Gao, Guiqun Wu, Xiangchen Gu et al. · Kidney & Blood Pressure Research | 2013 | 1,042 |
| 33 | Targeting the progression of chronic kidney disease Marta Ruiz‐Ortega, Sandra Rayego‐Mateos, Santiago Lamas et al. · Nature Reviews Nephrology | 14 Feb 2020 | 1,008 |
| 34 | Bone morphogenetic protein receptors and signal transduction Kohei Miyazono, Yuji Kamiya, Masato Morikawa · The Journal of Biochemistry | 17 Sep 2009 | 1,008 |
| 35 | The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing Joon-Il Jun, Lester F. Lau · Nature Cell Biology | 6 Jun 2010 | 992 |
| 36 | Lenvatinib, everolimus, and the combination in patients with metastatic renal cell carcinoma: a randomised, phase 2, open-label, multicentre trial Robert John Motzer, Thomas E. Hutson, Hilary Glen et al. · The Lancet Oncology | 25 Oct 2015 | 957 |
| 37 | Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma Arnaud Méjean et al. · New England Journal of Medicine | 3 Jun 2018 | 954 |
| 38 | Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-β Jose Garcia Abreu, Nan I. Ketpura, Bruno Reversade et al. · Nature Cell Biology | 22 Jul 2002 | 904 |
| 39 | Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma Jian Yu, Qingguo Xu, Zhenguang Wang et al. · Journal of Hepatology | 31 Jan 2018 | 892 |
| 40 | BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling cross-talk Kohei Miyazono, Shingo Maeda, Takeshi Imamura · Cytokine & Growth Factor Reviews | 25 May 2005 | 883 |
| 41 | TGF-β signaling in health and disease Joan Massagué, Dean Sheppard · Cell | Sep 2023 | 881 |
| 42 | Immunobiology of endometriosis Dan I. Lebovic, Michael David Mueller, Robert N. Taylor · Fertility and Sterility | 2001 | 867 |
| 43 | Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis Suk Paul Oh, Tsugio Seki, Kendrick A. Goss et al. · Proceedings of the National Academy of Sciences | 14 Mar 2000 | 865 |
| 44 | TGFβ Signaling: Receptors, Transducers, and Mad Proteins Joan Massagué · Cell | Jun 1996 | 842 |
| 45 | Specificity, versatility, and control of TGF-β family signaling Rik Derynck, Erine H. Budi · Science Signaling | 26 Feb 2019 | 822 |
| 46 | miR-133 and miR-30 Regulate Connective Tissue Growth Factor Rudy F.J.J. Duisters, Anke J. Tijsen, Blanche L. M. Schroen et al. · Circulation Research | 19 Dec 2008 | 821 |
| 47 | Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy Alain Ravaud et al. · New England Journal of Medicine | 10 Oct 2016 | 791 |
| 48 | Specificity, diversity, and regulation in TGF-beta superfamily signaling. Ester Piek, C HELDIN, Peter ten Dijke · PubMed | Dec 1999 | 783 |
| 49 | Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling. Jennifer A. Tuxhorn, Gustavo E. Ayala, Megan J. Smith et al. · PubMed | Sep 2002 | 781 |
| 50 | Stimulation of Fibroblast Cell Growth, Matrix Production, and Granulation Tissue Formation by Connective Tissue Growth Factor Ken S. Frazier, S. Williams, Devashish Kothapalli et al. · Journal of Investigative Dermatology | Sep 1996 | 771 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.