Most cited papers in Crystallization and Solubility Studies
What are the most cited papers in Crystallization and Solubility Studies?
The most cited paper in Crystallization and Solubility Studies is "Phaser crystallographic software" (Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Paul D. Adams et al., 2007), with 21,198 citations. Next come "ORTEP-3 for Windows - a version ofORTEP-III with a Graphical User Interface (GUI)" (19,952) and "WinGX suite for small-molecule single-crystal crystallography" (18,916).
Showing 50 of 99 papers. Every paper with more than 901 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Phaser crystallographic software Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Paul D. Adams et al. · Journal of Applied Crystallography | 13 Jul 2007 | 21,198 |
| 2 | ORTEP-3 for Windows - a version ofORTEP-III with a Graphical User Interface (GUI) Louis J. Farrugia · Journal of Applied Crystallography | Oct 1997 | 19,952 |
| 3 | WinGX suite for small-molecule single-crystal crystallography Louis J. Farrugia · Journal of Applied Crystallography | Aug 1999 | 18,916 |
| 4 | Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1 Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews | Mar 2001 | 18,154 |
| 5 | Structure validation in chemical crystallography Anthony L. Spek · Acta Crystallographica Section D Biological Crystallography | 19 Jan 2009 | 15,462 |
| 6 | Single-crystal structure validation with the program PLATON Anthony L. Spek · Journal of Applied Crystallography | 21 Jan 2003 | 14,093 |
| 7 | Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews | 1997 | 11,492 |
| 8 | Mercury CSD 2.0 – new features for the visualization and investigation of crystal structures Clare F. Macrae, Ian J. Bruno, James A. Chisholm et al. · Journal of Applied Crystallography | 8 Mar 2008 | 8,868 |
| 9 | XCII. Relations between the elastic moduli and the plastic properties of polycrystalline pure metals S.F. Pugh · The London Edinburgh and Dublin Philosophical Magazine and Journal of Science | Aug 1954 | 8,669 |
| 10 | Mercury : visualization and analysis of crystal structures Clare F. Macrae, Paul R. Edgington, Patrick McCabe et al. · Journal of Applied Crystallography | 10 May 2006 | 7,127 |
| 11 | Modeling and comparison of dissolution profiles Paulo C. Costa, José Manuel Sousa Lobo · European Journal of Pharmaceutical Sciences | May 2001 | 5,484 |
| 12 | A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research | Mar 1995 | 5,389 |
| 13 | The growth of crystals and the equilibrium structure of their surfaces W. K. Burton, N. Cabrera, Frederick Charles Frank · Philosophical Transactions of the Royal Society of London Series A Mathematical and Physical Sciences | 12 Jun 1951 | 5,353 |
| 14 | Supramolecular Synthons in Crystal Engineering—A New Organic Synthesis Gautam Radhakrishna Desiraju · Angewandte Chemie International Edition in English | 17 Nov 1995 | 4,858 |
| 15 | wannier90: A tool for obtaining maximally-localised Wannier functions Arash A. Mostofi, Jonathan R. Yates, Young‐Su Lee et al. · Computer Physics Communications | 28 Dec 2007 | 4,306 |
| 16 | SUPERFLIP – a computer program for the solution of crystal structures by charge flipping in arbitrary dimensions Lukáš Palatinus, G. Chapuis · Journal of Applied Crystallography | 13 Jul 2007 | 4,290 |
| 17 | Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling Peter Schuck · Biophysical Journal | Mar 2000 | 4,003 |
| 18 | BYPASS: an effective method for the refinement of crystal structures containing disordered solvent regions P. van der Sluis, Anthony L. Spek · Acta Crystallographica Section A Foundations of Crystallography | Mar 1990 | 3,798 |
| 19 | Towards quantitative analysis of intermolecular interactions with Hirshfeld surfaces Joshua J. McKinnon, Dylan Jayatilaka, Mark A. Spackman · Chemical Communications | 2007 | 3,556 |
| 20 | Cyclodextrins and their uses: a review Eva M. Martín del Valle · Process Biochemistry | 11 Oct 2003 | 3,359 |
| 21 | Ultrasound assisted extraction of food and natural products. Mechanisms, techniques, combinations, protocols and applications. A review Farid Chemat, Natacha Rombaut, Anne-Gaëlle Sicaire et al. · Ultrasonics Sonochemistry | 25 Jun 2016 | 3,214 |
| 22 | Nucleation and growth of thin films J. A. Venables, G. D. T. Spiller, Margrit Hanbücken · Reports on Progress in Physics | Apr 1984 | 2,927 |
| 23 | Sonochemistry Kenneth Sanders Suslick · Science | 23 Mar 1990 | 2,896 |
| 24 | Novel tools for visualizing and exploring intermolecular interactions in molecular crystals Joshua J. McKinnon, Mark A. Spackman, Anthony S. Mitchell · Acta Crystallographica Section B Structural Science | 9 Nov 2004 | 2,766 |
| 25 | Integration, scaling, space-group assignment and post-refinement Wolfgang Kabsch · Acta Crystallographica Section D Biological Crystallography | 21 Jan 2010 | 2,678 |
| 26 | Instabilities and pattern formation in crystal growth James S. Langer · Reviews of Modern Physics | 1980 | 2,637 |
| 27 | Improving drug solubility for oral delivery using solid dispersions C Leuner · European Journal of Pharmaceutics and Biopharmaceutics | 3 Jul 2000 | 2,576 |
| 28 | Imperfect Oriented Attachment: Dislocation Generation in Defect-Free Nanocrystals R. Lee Penn, Jillian F. Banfield · Science | 14 Aug 1998 | 2,428 |
| 29 | FactSage thermochemical software and databases Christopher William Bale, Patrice Chartrand, Sergei A. Degterov et al. · Calphad | Jun 2002 | 2,300 |
| 30 | Frequency factors and isotope effects in solid state rate processes George H. Vineyard · Journal of Physics and Chemistry of Solids | 1957 | 2,277 |
| 31 | Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases Lewis M. Siegel, Kenneth J. Monty · Biochimica et Biophysica Acta (BBA) - Biophysics including Photosynthesis | Feb 1966 | 2,239 |
| 32 | Drug Solubility: Importance and Enhancement Techniques Ketan T. Savjani, Anuradha Ketan Gajjar, Jignasa Savjani · ISRN Pharmaceutics | 5 Jul 2012 | 2,013 |
| 33 | Review: A History of Cyclodextrins Grégorio Crini · Chemical Reviews | 23 Sep 2014 | 1,903 |
| 34 | Green Extraction of Natural Products: Concept and Principles Farid Chemat, Maryline Abert Vian, Giancarlo Cravotto · International Journal of Molecular Sciences | 11 Jul 2012 | 1,888 |
| 35 | Cyclodextrins as pharmaceutical solubilizers Marcus Eli Brewster, Þorsteinn Loftsson · Advanced Drug Delivery Reviews | 30 May 2007 | 1,879 |
| 36 | Pharmaceutical Applications of Solid Dispersion Systems Win Loung Chiou, Sidney Riegelman · Journal of Pharmaceutical Sciences | Sep 1971 | 1,795 |
| 37 | Cyclodextrins and their pharmaceutical applications Þorsteinn Loftsson, Dominique Duchêne · International Journal of Pharmaceutics | 10 Nov 2006 | 1,734 |
| 38 | Mesocrystals: Inorganic Superstructures Made by Highly Parallel Crystallization and Controlled Alignment Helmut Cölfen, Markus Antonietti · Angewandte Chemie International Edition | 20 Jul 2005 | 1,730 |
| 39 | DDSolver: An Add-In Program for Modeling and Comparison of Drug Dissolution Profiles Yong Zhang, Meirong Huo, Jianping Zhou et al. · The AAPS Journal | 5 Apr 2010 | 1,653 |
| 40 | Solid dispersion of poorly water‐soluble drugs: Early promises, subsequent problems, and recent breakthroughs Abu T.M. Serajuddin · Journal of Pharmaceutical Sciences | Oct 1999 | 1,650 |
| 41 | Synthesis and characterization of hydroxyapatite crystals: A review study on the analytical methods Sotirios Koutsopoulos · Journal of Biomedical Materials Research | 6 Sep 2002 | 1,641 |
| 42 | A Bayesian Mixture Model for Across-Site Heterogeneities in the Amino-Acid Replacement Process Nicolas Lartillot, Hervé Philippe · Molecular Biology and Evolution | 15 Mar 2004 | 1,628 |
| 43 | An introduction to data reduction: space-group determination, scaling and intensity statistics Philip Rainsford Evans · Acta Crystallographica Section D Biological Crystallography | 17 Mar 2011 | 1,584 |
| 44 | Step Motion on Crystal Surfaces Richard L. Schwoebel, Edward J. Shipsey · Journal of Applied Physics | Sep 1966 | 1,583 |
| 45 | Strategies to Address Low Drug Solubility in Discovery and Development Hywel D. Williams, Natalie L. Trevaskis, Susan A. Charman et al. · Pharmacological Reviews | 2013 | 1,574 |
| 46 | Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs Teófilo Vasconcelos, Bruno Filipe Carmelino Cardoso Sarmento, Paulo C. Costa · Drug Discovery Today | Dec 2007 | 1,565 |
| 47 | Crystal Engineering: From Molecule to Crystal Gautam Radhakrishna Desiraju · Journal of the American Chemical Society | 10 Jun 2013 | 1,519 |
| 48 | Crystal Engineering: A Holistic View Gautam Radhakrishna Desiraju · Angewandte Chemie International Edition | 27 Sep 2007 | 1,499 |
| 49 | Understanding Pharmaceutical Quality by Design Lawrence X. Yu, Gregory E. Amidon, Mansoor A. Khan et al. · The AAPS Journal | 22 May 2014 | 1,458 |
| 50 | Powder pattern indexing with the dichotomy method Ali Boultif, Daniel Louer · Journal of Applied Crystallography | 11 Sep 2004 | 1,455 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.