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Most cited papers in dental development and anomalies

What are the most cited papers in dental development and anomalies?

The most cited paper in dental development and anomalies is "Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo" (Stan Gronthos, Mahesh H. Mankani, Jaime S. Brahim et al., 2000), with 4,630 citations. Next come "SHED: Stem cells from human exfoliated deciduous teeth" (3,040) and "Hedgehog signaling in animal development: paradigms and principles" (3,024).

Showing 50 of 100 papers. Every paper with more than 616 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo Stan Gronthos, Mahesh H. Mankani, Jaime S. Brahim et al. · Proceedings of the National Academy of Sciences Open access 21 Nov 2000 4,630
2 SHED: Stem cells from human exfoliated deciduous teeth Masako Miura, Stan Gronthos, Mingrui Zhao et al. · Proceedings of the National Academy of Sciences Open access 25 Apr 2003 3,040
3 Hedgehog signaling in animal development: paradigms and principles Philip William Ingham, Andrew P. McMahon · Genes & Development Open access Dec 2001 3,024
4 Isolation of a Mouse Submaxillary Gland Protein Accelerating Incisor Eruption and Eyelid Opening in the New-born Animal Stanley Cohen · Journal of Biological Chemistry Open access May 1962 2,204
5 Stem Cell Properties of Human Dental Pulp Stem Cells Stan Gronthos, Jaime S. Brahim, Wangliang Li et al. · Journal of Dental Research Aug 2002 2,126
6 Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein Andrea Vortkamp, Kaechoong Lee, Beate Lanske et al. · Science 2 Aug 1996 2,009
7 Bone morphogenetic proteins: multifunctional regulators of vertebrate development. B L Hogan · Genes & Development Open access Jul 1996 1,995
8 Dimensional ridge alterations following tooth extraction. An experimental study in the dog Maurício G. Araújo, Jan Lindhe · Journal Of Clinical Periodontology Feb 2005 1,968
9 Mesenchymal Stem Cells Derived from Dental Tissues vs . Those from Other Sources: Their Biology and Role in Regenerative Medicine G.T.-J. Huang, Stan Gronthos, Songtao Shi · Journal of Dental Research Open access Sep 2009 1,892
10 Reaching a Genetic and Molecular Understanding of Skeletal Development Gérard Karsenty, Erwin Friedrich Wagner · Developmental Cell Open access Apr 2002 1,620
11 Widespread Parallel Evolution in Sticklebacks by Repeated Fixation of Ectodysplasin Alleles Pamela F. Colosimo, Kim E. Hosemann, Sarita Balabhadra et al. · Science 24 Mar 2005 1,562
12 Brief communication: The London atlas of human tooth development and eruption Sakher J. AlQahtani, Mark Hector, Helen Mary Liversidge · American Journal of Physical Anthropology 22 Mar 2010 1,530
13 Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia Stefan Mundlos, F Otto, C Mundlos et al. · Cell Open access May 1997 1,507
14 Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis Yang Chai, Xiaobing Jiang, Yoshihiro Ito et al. · Development 15 Apr 2000 1,480
15 HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo Mark Joseph Bitgood, Andrew P. McMahon · Developmental Biology Open access Nov 1995 1,387
16 Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats C. Maniatopoulos, Jaro Sodek, A. H. Melcher · Cell and Tissue Research Nov 1988 1,334
17 Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development Ichiro Satokata, Richard L. Maas · Nature Genetics Apr 1994 1,285
18 The genomic landscape of Neanderthal ancestry in present-day humans Sriram S Sankararaman, Swapan Mallick, Michael Dannemann et al. · Nature Open access 28 Jan 2014 1,236
19 Characterization of the Apical Papilla and Its Residing Stem Cells from Human Immature Permanent Teeth: A Pilot Study Wataru Sonoyama, Yi Liu, Takayoshi Yamaza et al. · Journal of Endodontics Open access 21 Jan 2008 1,235
20 Mechanisms of bone development and repair Ankit Salhotra, Harsh N. Shah, Benjamin Lévi et al. · Nature Reviews Molecular Cell Biology ReviewOpen access 8 Sep 2020 1,208
21 Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene. Andrew C. Karaplis, A. Luz, Julie Glowacki et al. · Genes & Development Open access Feb 1994 1,166
22 New attachment following surgical treatment of human periodontal disease Sture R. Nyman, Jan Lindhe, Thorkild Karring et al. · Journal Of Clinical Periodontology Aug 1982 1,124
23 Reiterative signaling and patterning during mammalian tooth morphogenesis Jukka Jernvall, Irma Thesleff · Mechanisms of Development Open access Mar 2000 1,118
24 The Effect of the Distance From the Contact Point to the Crest of Bone on the Presence or Absence of the Interproximal Dental Papilla Dennis P. Tarnow, Anne W. Magner, Paul D. Fletcher · Journal of Periodontology Dec 1992 1,089
25 Osteopontin: a protein with diverse functions David T. Denhardt, Xiaojia Guo · The FASEB Journal Dec 1993 1,084
26 Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture Klaus von der Mark, Verena Gauss, Helga von der Mark et al. · Nature Jun 1977 1,080
27 Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival David T. Denhardt, Masaki Noda, Anthony W O'Regan et al. · Journal of Clinical Investigation Open access May 2001 1,072
28 Cellular, molecular, and tissue-level reactions to orthodontic force Vinod Krishnan, Ze’ev Davidovitch · American Journal of Orthodontics and Dentofacial Orthopedics Apr 2006 1,071
29 Molecular Mechanisms Mediating Proliferation/Differentiation Interrelationships During Progressive Development of the Osteoblast Phenotype Gary S. Stein, Jane B. Lian · Endocrine Reviews Aug 1993 1,055
30 Abnormal lung development and cleft palate in mice lacking TGF–β3 indicates defects of epithelial–mesenchymal interaction Vesa Kaartinen, Jan Willem Voncken, Charles F. Shuler et al. · Nature Genetics Dec 1995 1,039
31 Distinct roles for Hedgehog and canonical Wnt signaling in specification,differentiation and maintenance of osteoblast progenitors Stephen J. Rodda, Andrew P. McMahon · Development 20 Jul 2006 1,019
32 Bone Dysplasia Sclerosteosis Results from Loss of the SOST Gene Product, a Novel Cystine Knot–Containing Protein Mary E. Brunkow, Jessica C. Gardner, Jeff Van Ness et al. · The American Journal of Human Genetics Open access Mar 2001 1,016
33 Osteopontin Jaro Sodek, B. Ganss, Marc D. McKee · Critical Reviews in Oral Biology & Medicine Open access Jul 2000 991
34 A meta‐analysis of the prevalence of dental agenesis of permanent teeth Bart J. Polder, Martin A. van’t Hof, F.P.G.M. van der Linden et al. · Community Dentistry And Oral Epidemiology 19 May 2004 980
35 Isolation of precursor cells (PCs) from human dental follicle of wisdom teeth Christian O. Morsczeck, Werner Götz, Jörg Michael Schierholz et al. · Matrix Biology 15 Feb 2005 923
36 Transforming growth factor–β3 is required for secondary palate fusion Gabriele Proetzel, Sharon A. Pawlowski, Michael V. Wiles et al. · Nature Genetics Open access Dec 1995 912
37 Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development Seppo Juhani Vainio, Irina D. Karavanova, Adrian K. Jowett et al. · Cell Oct 1993 907
38 Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome Elena V. Semina, Rebecca S. Reiter, Nancy J. Leysens et al. · Nature Genetics Dec 1996 890
39 An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis Laurence De Moerlooze, Bradley Spencer‐Dene, Jean‐Michel Revest et al. · Development Feb 2000 871
40 Efficacy of clear aligners in controlling orthodontic tooth movement: A systematic review Gabriele Rossini, Simone Parrini, Tommaso Castroflorio et al. · The Angle Orthodontist ReviewOpen access 20 Nov 2014 863
41 Mineralized bone nodules formedin vitro from enzymatically released rat calvaria cell populations C.G. Bellows, Jane E. Aubin, Johan N.M. Heersche et al. · Calcified Tissue International May 1986 849
42 Comparing the Perception of Dentists and Lay People to Altered Dental Esthetics Vincent O. Kokich, H. Asuman Kiyak, Peter A. Shapiro · Journal of Esthetic and Restorative Dentistry Nov 1999 844
43 Pax9 -deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities Heiko Peters, Annette Neubüser, Klaus Kratochwil et al. · Genes & Development Open access Sep 1998 842
44 New attachment formation in the human periodontium by guided tissue regeneration Case reports Jan Gottlow, Sture R. Nyman, Jan Lindhe et al. · Journal Of Clinical Periodontology Jul 1986 831
45 Bone Development Bjorn Reino Olsen, Anthony M. Reginato, Wenfang Wang · Annual Review of Cell and Developmental Biology Review Nov 2000 830
46 Facial keys to orthodontic diagnosis and treatment planning. Part I G. William Arnett, Robert T. Bergman · American Journal of Orthodontics and Dentofacial Orthopedics Apr 1993 824
47 Sonic hedgehog regulates growth and morphogenesis of the tooth Hélène R. Dassule, Paula M. Lewis, Marianna Bei et al. · Development 15 Nov 2000 818
48 Indian Hedgehog: A Mechanotransduction Mediator in Condylar Cartilage Guo Hua Tang, A. Bakr M. Rabie, Urban Hägg · Journal of Dental Research May 2004 818
49 Some esthetic factors in a smile Anthony H.L. Tjan, Gary D. Miller, Josephine G.P. The · Journal of Prosthetic Dentistry 1984 817
50 Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein Pao‐Tien Chuang, Andrew P. McMahon · Nature Feb 1999 802

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.