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Topic · Molecular Biology

dental development and anomalies

dental development and anomalies is a research topic within Molecular Biology. Science Explorer counts 25k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the molecular mechanisms, genetic regulation, and signaling pathways involved in tooth development, morphogenesis, and anomalies such as hypodontia and ectodermal dysplasia. It delves into the role of epithelial-mesenchymal interactions, stem cell niches, and key signaling pathways like Wnt/ß-catenin in shaping the dentition.

  • Tooth Development
  • Molecular Signaling
  • Ectodermal Dysplasia
  • Genetic Regulation
  • Epithelial-Mesenchymal Interactions
  • Stem Cell Niche
  • Wnt/ß-catenin Signaling
  • Hypodontia
  • Odontogenesis
  • Gene Mutations
Research works
25k
fractional, since 1950
In the world top 10%
2.5k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+15%
the tick is no change
Largest producer
India
22% of the 10 largest, 2022-now
dental development and anomalies

Which countries lead dental development and anomalies research?

By volume, India and China publish the most (628 and 495 works in 2022-now).

By volume, 2022-now

  1. 1 India 628 works
  2. 2 China 495 works
  3. 3 United States 460 works
  4. 4 Brazil 334 works
  5. 5 Türkiye 264 works
  6. 6 Japan 202 works
  7. 7 Italy 153 works
  8. 8 United Kingdom 152 works
  9. 9 Saudi Arabia 119 works
  10. 10 Iran 110 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

India: 21.5%China: 17.0%United States: 15.8%Brazil: 11.4%6 others listed: 34.3%22%largest
India628 · 21.5%China495 · 17.0%United States460 · 15.8%Brazil334 · 11.4%6 others listed1,001 · 34.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead dental development and anomalies research?

By volume in 2022-now, Sichuan University publishes the most dental development and anomalies research, followed by Stomatology Hospital and Universidade de São Paulo.

By volume, 2022-now

  1. 1 Sichuan UniversityChina 46 works
  2. 2 Stomatology HospitalChina 45 works
  3. 3 Universidade de São PauloBrazil 31 works
  4. 4 Saveetha UniversityIndia 29 works
  5. 5 Government Dental College and HospitalIndia 23 works
  6. 6 Datta Meghe Institute of Higher Education and ResearchIndia 20 works
  7. 7 Kamineni Institute of Dental SciencesIndia 19 works
  8. 8 American Association of OrthodontistsUnited States 19 works
  9. 9 Govt. Dental College & HospitalIndia 19 works
  10. 10 King's College LondonUnited Kingdom 18 works

Who are the leading researchers in dental development and anomalies?

The most-cited researchers publishing on dental development and anomalies include George Davey Smith, Richard A. Gibbs and Yousef Saleh Khader.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Richard A. Gibbs United States 292k citations
  3. 3 Yousef Saleh Khader Jordan 274k citations
  4. 4 André Gerardus Uitterlinden Netherlands 246k citations
  5. 5 Eric Boerwinkle United States 232k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in dental development and anomalies?

The most cited paper in dental development and anomalies is "Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo" (Stan Gronthos, Mahesh H. Mankani, Jaime S. Brahim et al., 2000), with 4,630 citations. Next come "SHED: Stem cells from human exfoliated deciduous teeth" (3,040) and "Hedgehog signaling in animal development: paradigms and principles" (3,024).

Most cited papers
#PaperReleasedCitations
1 Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo Stan Gronthos, Mahesh H. Mankani, Jaime S. Brahim et al. · Proceedings of the National Academy of Sciences Open access 21 Nov 2000 4,630
2 SHED: Stem cells from human exfoliated deciduous teeth Masako Miura, Stan Gronthos, Mingrui Zhao et al. · Proceedings of the National Academy of Sciences Open access 25 Apr 2003 3,040
3 Hedgehog signaling in animal development: paradigms and principles Philip William Ingham, Andrew P. McMahon · Genes & Development Open access Dec 2001 3,024
4 Isolation of a Mouse Submaxillary Gland Protein Accelerating Incisor Eruption and Eyelid Opening in the New-born Animal Stanley Cohen · Journal of Biological Chemistry Open access May 1962 2,204
5 Stem Cell Properties of Human Dental Pulp Stem Cells Stan Gronthos, Jaime S. Brahim, Wangliang Li et al. · Journal of Dental Research Aug 2002 2,126
All 100 most cited papers, with filters and sorting

Where is dental development and anomalies research done?

The largest centres of dental development and anomalies research in 2022-now are Xi'an (China), Chennai (India), São Paulo (Brazil) and Istanbul (Türkiye). Among places with at least 20 works in it, it is an unusually large share of all research in Wardha.

Largest cities, 2022-now

  1. 1 Xi'anChina 78 works
  2. 2 ChennaiIndia 76 works
  3. 3 São PauloBrazil 66 works
  4. 4 IstanbulTürkiye 62 works
  5. 5 BeijingChina 57 works
  6. 6 LondonUnited Kingdom 54 works
  7. 7 TokyoJapan 50 works
  8. 8 SeoulSouth Korea 46 works
  9. 9 AnkaraTürkiye 46 works
  10. 10 RiyadhSaudi Arabia 43 works

Where it is the local speciality

  1. WardhaIN · 20.4 works18×
← less than its size predicts1×more →

Location quotient: how much more of its research is in dental development and anomalies than the world average.

See dental development and anomalies on the map

Where is the best place to study dental development and anomalies?

Among universities, judged by research, Sichuan University, Damascus University and The University of Adelaide score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 22.3%fractional works in this field (log) →share of work in the world top 10% →The University of Ad…Damascus UniversityNational and Kapodis…Sichuan University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Sichuan UniversityChina 81.423.1%5.0×46 +22.5%
2Damascus UniversitySyria 67.227.3%40.4×13 +134.3%
3The University of AdelaideAustralia 65.232.2%6.6×11 +58.5%
4National and Kapodistrian University of AthensGreece 62.025.9%5.8×12 +31.5%
5Saveetha UniversityIndia 60.911.3%7.7×29 +29.5%
6Capital Medical UniversityChina 59.220.3%3.9×17 +33.2%
7King's College LondonUnited Kingdom 59.114.5%5.1×18 +43.6%
8University of BernSwitzerland 57.727.8%4.3×10 +8.3%
9Air Force Medical UniversityChina 56.721.7%24.6×16 +271.9%
10Harvard UniversityUnited States 56.318.9%1.0×13 +18.2%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in dental development and anomalies, country by country

Is dental development and anomalies research growing?

Output in 2022-2025 was 15% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are dental development and anomalies.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is dental development and anomalies as a percentage of every work published that year, 0.019% in 2024.

still counting0.020%0.040%dental development and anomalies0.020% in 202519801990200020102020

Fractional works of dental development and anomalies over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%dental development and anomalies10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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