Science Explorer Back to mapMap

Most cited papers in Drug-Induced Adverse Reactions

What are the most cited papers in Drug-Induced Adverse Reactions?

The most cited paper in Drug-Induced Adverse Reactions is "Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients" (Munir Pirmohamed, Sally James, Shaun Meakin et al., 2004), with 3,262 citations. Next come "Sarcoidosis" (1,973) and "HLA-B*5701 Screening for Hypersensitivity to Abacavir" (1,847).

Showing 50 of 100 papers. Every paper with more than 542 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients Munir Pirmohamed, Sally James, Shaun Meakin et al. · BMJ Open access Jul 2004 3,262
2 Sarcoidosis Michael C. Iannuzzi, Benjamin A. Rybicki, Alvin S. Teirstein · New England Journal of Medicine 21 Nov 2007 1,973
3 HLA-B*5701 Screening for Hypersensitivity to Abacavir Simon Alexander Mallal, Elizabeth Jane Phillips, Giampiero Carosi et al. · New England Journal of Medicine Open access 6 Feb 2008 1,847
4 A marker for Stevens–Johnson syndrome Wen‐Hung Chung, Wen‐Hung Chung, Hong‐Shang Hong et al. · Nature Apr 2004 1,760
5 Cremophor EL Hans A. J. Gelderblom, Jaap Verweij, Kees Nooter et al. · European Journal of Cancer Sep 2001 1,658
6 Clinical Classification of Cases of Toxic Epidermal Necrolysis, Stevens-Johnson Syndrome, and Erythema Multiforme Sylvie Bastuji‐Garin · Archives of Dermatology 1993 1,632
7 Severe Adverse Cutaneous Reactions to Drugs Jean Claude Roujeau, Robert S. Stern · New England Journal of Medicine 10 Nov 1994 1,578
8 Medication Use and the Risk of Stevens–Johnson Syndrome or Toxic Epidermal Necrolysis Jean‐Claude Roujeau, Judith Parsells Kelly, Luigi Naldi et al. · New England Journal of Medicine 14 Dec 1995 1,473
9 European Society of Contact Dermatitis guideline for diagnostic patch testing – recommendations on best practice Jeanne Duus Johansen et al. · Contact Dermatitis Open access 14 Jul 2015 1,448
10 Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin Francesca Catella-Lawson, Muredach P. Reilly, Shiv C. Kapoor et al. · New England Journal of Medicine Open access 20 Dec 2001 1,412
11 Association between presence of HLA-B*5701, HLA-DR7 , and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir Simon Alexander Mallal, David A Nolan, Campbell S. Witt et al. · The Lancet Mar 2002 1,387
12 A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions Eugène van Puijenbroek, Andrew M. Bate, Hubert G.M. Leufkens et al. · Pharmacoepidemiology and Drug Safety 2002 1,385
13 HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol Wen‐Hung Chung, Wen‐Hung Chung, Lieh-Bang Liou et al. · Proceedings of the National Academy of Sciences Open access 2 Mar 2005 1,295
14 Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up John B.A.G. Haanen, Michel Obéid, Lavinia Anne Spain et al. · Annals of Oncology Open access 18 Oct 2022 1,285
15 Risk for Serious Gastrointestinal Complications Related to Use of Nonsteroidal Anti-inflammatory Drugs Sherine E. Gabriel, Liisa Jaakkimainen, Claire Bombardier · Annals of Internal Medicine 15 Nov 1991 1,248
16 Sarcoidosis Lee Scott Newman, Cecile Stephanie Rose, Lisa A. Maier · New England Journal of Medicine 24 Apr 1997 1,241
17 SCORTEN: A Severity-of-Illness Score for Toxic Epidermal Necrolysis Nathalie Fouchard, M. Bertocchi, Jean‐Claude Roujeau et al. · Journal of Investigative Dermatology Open access Aug 2000 1,202
18 Diagnostic criteria and classification of mastocytosis: a consensus proposal Peter Valent, Hans‐P. Horny, Luís Escribano et al. · Leukemia Research Jul 2001 1,117
19 Cytokine modulation of atopic dermatitis filaggrin skin expression Michael D Howell, Byung Eui Kim, Peisong Gao et al. · Journal of Allergy and Clinical Immunology Open access 25 May 2007 1,098
20 Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology Antonella Maria Muraro et al. · Allergy Open access 9 Jun 2014 1,059
21 Racial Differences in Sarcoidosis Incidence: A 5-Year Study in a Health Maintenance Organization Benjamin A. Rybicki, Marcie L. Major, John Popovich et al. · American Journal of Epidemiology Feb 1997 1,024
22 Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Assessment of Medication Risks with Emphasis on Recently Marketed Drugs. The EuroSCAR-Study Maja Mockenhaupt, Cecile G. Viboud, Ariane Dunant et al. · Journal of Investigative Dermatology Open access 6 Sep 2007 1,020
23 Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study Sylvia Helena Kardaun, Peggy Sekula, L. Valeyrie‐Allanore et al. · British Journal of Dermatology 16 Jul 2013 1,018
24 The DRESS Syndrome: A Literature Review P. Cacoub, Philippe Musette, Vincent Descamps et al. · The American Journal of Medicine 22 May 2011 1,017
25 Inhibition of Toxic Epidermal Necrolysis by Blockade of CD95 with Human Intravenous Immunoglobulin I. Viard, Philippe Wehrli, Roberto R. Bullani et al. · Science 16 Oct 1998 1,011
26 Clinical features and severity grading of anaphylaxis Simon G.A. Brown · Journal of Allergy and Clinical Immunology Aug 2004 1,005
27 Risk of upper gastrointestinal bleeding and perforation associated with Individual non-steroidal anti-inflammatory drugs La García Rodríguez, Hershel Jick · The Lancet Mar 1994 978
28 Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2 Makoto Murakami, Hiroaki Naraba, Toshihiro Tanioka et al. · Journal of Biological Chemistry Open access Oct 2000 971
29 Drug-induced pseudolymphoma and drug hypersensitivity syndrome (drug rash with eosinophilia and systemic symptoms: DRESS) Hélène Bocquet, Martine Bagot, Jean Claude Roujeau · Seminars in Cutaneous Medicine and Surgery Dec 1996 967
30 Adverse Effects of Nonsteroidal Antiinflammatory Drugs: An Update of Gastrointestinal, Cardiovascular and Renal Complications Sam Harirforoosh, Waheed Asghar, Fakhreddin Jamali · Journal of Pharmacy & Pharmaceutical Sciences Open access 27 Jan 2014 967
31 International Con sensus on drug allergy Pascal M. Demoly, N. Franklin Adkinson, Knut Brockow et al. · Allergy Open access 21 Feb 2014 937
32 Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist? Sylvia Helena Kardaun, Alexis Sidoroff, L. Valeyrie‐Allanore et al. · British Journal of Dermatology 19 Jan 2007 933
33 HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans Mark McCormack et al. · New England Journal of Medicine Open access 23 Mar 2011 926
34 Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs Michael J. S. Langman, J Weil, Paul Wainwright et al. · The Lancet Apr 1994 878
35 Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials Yucai Wang, Shouhao Zhou, Fang Yang et al. · JAMA Oncology Open access 25 Apr 2019 873
36 Pneumocystis carinii Pneumonia: A Comparison Between Patients with the Acquired Immunodeficiency Syndrome and Patients with Other Immunodeficiencies Joseph A. Kovacs, JOHN W. HIEMENZ, ABE M. MACHER et al. · Annals of Internal Medicine May 1984 859
37 Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis Wen‐Hung Chung, Wen‐Hung Chung, Jui‐Yung Yang et al. · Nature Medicine 23 Nov 2008 838
38 Health care use and serious infection prevalence associated with penicillin “allergy” in hospitalized patients: A cohort study Eric M. Macy, Richard Contreras · Journal of Allergy and Clinical Immunology Nov 2013 834
39 Evaluation and Management of Penicillin Allergy Erica Seiguer Shenoy, Eric M. Macy, Theresa A. Rowe et al. · JAMA 15 Jan 2019 828
40 Drug provocation testing in the diagnosis of drug hypersensitivity reactions: general considerations Werner Aberer, Andreas J. Bircher, Antonino G. Romano et al. · Allergy 4 Aug 2003 822
41 Acute generalized exanthematous pustulosis (AGEP) – A clinical reaction pattern Alexis Sidoroff, Sima Halevy, Jan Nico Bouwes Bavinck et al. · Journal of Cutaneous Pathology Open access Mar 2001 815
42 Genetic variations in HLA-B region and hypersensitivity reactions to abacavir Seth Hetherington, Arlene R. Hughes, Michael Mosteller et al. · The Lancet Mar 2002 813
43 Skin test concentrations for systemically administered drugs – an ENDA / EAACI Drug Allergy Interest Group position paper Knut Brockow et al. · Allergy Open access 25 Apr 2013 812
44 Use of Nonsteroidal Antiinflammatory Drugs Elliott Marshall Antman, JOEL S. BENNETT, Alan Daugherty et al. · Circulation 27 Feb 2007 811
45 Manifestations of sarcoidosis Robert L. Mayock, Pierre Bertrand, Claire E. Morrison et al. · The American Journal of Medicine Jul 1963 807
46 Tetracyclines: Nonantibiotic properties and their clinical implications Allen N. Sapadin, Raúl Fleischmajer · Journal of the American Academy of Dermatology 27 Jan 2006 775
47 Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations Faviel F. González-Galarza, Louise Y.C. Takeshita, Eduardo José Melo dos Santos et al. · Nucleic Acids Research Open access 20 Nov 2014 765
48 ALDEN, an Algorithm for Assessment of Drug Causality in Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Comparison With Case–Control Analysis Bruno Sassolas, Cynthia Haddad, Maja Mockenhaupt et al. · Clinical Pharmacology & Therapeutics 7 Apr 2010 755
49 Standards and standardization in mastocytosis: Consensus Statements on Diagnostics, Treatment Recommendations and Response Criteria Peter Valent et al. · European Journal of Clinical Investigation 26 May 2007 751
50 Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials Philippe Gevaert, Theodore A. Omachi, Jonathan Corren et al. · Journal of Allergy and Clinical Immunology Open access 7 Jun 2020 740

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.