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Most cited papers in Drug-Induced Ocular Toxicity

What are the most cited papers in Drug-Induced Ocular Toxicity?

The most cited paper in Drug-Induced Ocular Toxicity is "Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology" (Eva Vanessa Schrezenmeier, Thomas Dörner, 2020), with 1,519 citations. Next come "Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients" (1,440) and "Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)" (1,287).

Showing 50 of 99 papers. Every paper with more than 290 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology Eva Vanessa Schrezenmeier, Thomas Dörner · Nature Reviews Rheumatology Review 7 Feb 2020 1,519
2 Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients Zhixiang Shen, Guoqiang Chen, Jian-Hua Ni et al. · Blood May 1997 1,440
3 Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid) Raymond P. Warrell, Stanley R. Frankel, Wilson H. Miller et al. · New England Journal of Medicine Open access 16 May 1991 1,287
4 Characteristics of Ocular Findings of Patients With Coronavirus Disease 2019 (COVID-19) in Hubei Province, China Ping Wu, Fang Duan, Chunhua Luo et al. · JAMA Ophthalmology Open access 31 Mar 2020 1,285
5 All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results [see comments] Sylvie Castaigné, Christine Chomienne, MT Daniel et al. · Blood Nov 1990 1,205
6 Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy (2016 Revision) Michael F. Marmor, Ulrich Kellner, Timothy Y. Y. Lai et al. · Ophthalmology Open access 16 Mar 2016 1,189
7 POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN Abdulrahman Mahgoub, L. Graham Dring, Jeffrey R. Idle et al. · The Lancet Sep 1977 1,189
8 All-trans-Retinoic Acid in Acute Promyelocytic Leukemia Martin S. Tallman, Janet W. Andersen, Charles Alan Schiffer et al. · New England Journal of Medicine 9 Oct 1997 1,099
9 A Molecular Marker for Chloroquine-Resistant Falciparum Malaria ABDOULAYE A. DJIMDÉ, O K Doumbo, Joseph F. Cortese et al. · New England Journal of Medicine Open access 25 Jan 2001 1,035
10 Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review Guillermo Ruiz‐Irastorza, Manuel Ramos‐Casals, Pilar Brito‐Zerón et al. · Annals of the Rheumatic Diseases Review 22 Dec 2008 990
11 ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY OF THE CHOROID IN CENTRAL SEROUS CHORIORETINOPATHY Yutaka Imamura, Takamitsu Fujiwara, Ron Margolis et al. · Retina Nov 2009 973
12 United States Multicenter Study of Arsenic Trioxide in Relapsed Acute Promyelocytic Leukemia Steven L. Soignet, Stanley R. Frankel, Dan Douer et al. · Journal of Clinical Oncology 15 Sep 2001 829
13 Anti-Hu-Associated Paraneoplastic Encephalomyelitis/Sensory Neuronopathy A Clinical Study of 71 Patients Josep O. Dalmau, Francesc Graus, Marc k. Rosenblum et al. · Medicine Mar 1992 825
14 The "Retinoic Acid Syndrome" in Acute Promyelocytic Leukemia Stanley R. Frankel, Anna Eardley, Gregory Yves Lauwers et al. · Annals of Internal Medicine Open access 15 Aug 1992 722
15 Association of Elevated Serum Lipid Levels With Retinal Hard Exudate in Diabetic Retinopathy Emily Y. Chew · Archives of Ophthalmology Sep 1996 716
16 Revised Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Michael F. Marmor, Ulrich Kellner, Timothy Y. Y. Lai et al. · Ophthalmology Feb 2011 716
17 Sensory Neuropathy from Pyridoxine Abuse Herbert H. Schaumburg, Jerry G. Kaplan, Anthony J. Windebank et al. · New England Journal of Medicine 25 Aug 1983 710
18 The Risk of Toxic Retinopathy in Patients on Long-term Hydroxychloroquine Therapy Ronald B. Melles, Michael F. Marmor · JAMA Ophthalmology 2 Oct 2014 696
19 Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications James R. O’Dell, Claire E. Haire, Nils Erikson et al. · New England Journal of Medicine Open access 16 May 1996 655
20 COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression Dan Zhou, Sheng‐Ming Dai, Qiang Tong · Journal of Antimicrobial Chemotherapy Open access 6 Mar 2020 631
21 Studies on Treatment of Acute Promyelocytic Leukemia With Arsenic Trioxide: Remission Induction, Follow-Up, and Molecular Monitoring in 11 Newly Diagnosed and 47 Relapsed Acute Promyelocytic Leukemia Patients Chao Niu et al. · Blood 15 Nov 1999 629
22 Hydroxychloroquine: From Malaria to Autoimmunity Ilan Ben‐Zvi, Shaye Kivity, Pnina Langevitz et al. · Clinical Reviews in Allergy & Immunology Open access 6 Jan 2011 623
23 The Overexpression of Bax Produces Cell Death upon Induction of the Mitochondrial Permeability Transition John G. Pastorino, Sing-Tsung Chen, Marco Tafani et al. · Journal of Biological Chemistry Open access Mar 1998 587
24 New insights into the antiviral effects of chloroquine Andrea Savarino, Livia Di Trani, Isabella Donatelli et al. · The Lancet Infectious Diseases Open access 27 Jan 2006 582
25 Trends and mortality effects of vitamin A deficiency in children in 138 low-income and middle-income countries between 1991 and 2013: a pooled analysis of population-based surveys Gretchen A Stevens, James E. Bennett, Quentin Hennocq et al. · The Lancet Global Health Open access 29 Aug 2015 577
26 Some puzzling pharmacological effects of monoamine oxidase inhibitors. Joseph Edward Knoll, Kálmán Magyar · PubMed 1972 562
27 Of chloroquine and COVID-19 Franck Touret, Xavier Nicolas de Lamballerie · Antiviral Research Open access 6 Mar 2020 559
28 Therapy and pharmacological properties of hydroxychloroquine and chloroquine in treatment of systemic lupus erythematosus, rheumatoid arthritis and related diseases Kim Drummond Rainsford, Ann L. Parke, Matthew Clifford‐Rashotte et al. · Inflammopharmacology 5 Aug 2015 553
29 Arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML17): results of a randomised, controlled, phase 3 trial Alan K. Burnett, Nigel H. Russell, Robert K. Hills et al. · The Lancet Oncology 14 Sep 2015 548
30 Hydroxychloroquine in lupus pregnancy Megan E. B. Clowse, Laurence S. Magder, Frank R. Witter et al. · Arthritis & Rheumatism 30 Oct 2006 540
31 Effect of hydroxychloroquine on the survival of patients with systemic lupus erythematosus: data from LUMINA, a multiethnic US cohort (LUMINA L) Graciela S. Alarcón, Gerald McGwin, Ana María Bertoli et al. · Annals of the Rheumatic Diseases Open access 27 Mar 2007 538
32 Thalidomide in the treatment of lepra reactions Jacob Sheskin · Clinical Pharmacology & Therapeutics May 1965 534
33 Leber hereditary optic neuropathy Patrick Yu Wai Man, D M Turnbull, P F Chinnery · Journal of Medical Genetics Open access Mar 2002 525
34 Effect of all transretinoic acid in newly diagnosed acute promyelocytic leukemia. Results of a multicenter randomized trial. European APL 91 Group Pierre Fenaux, M-C. Le Deley, Sylvie Castaigné et al. · Blood Open access Dec 1993 521
35 Definition of glaucoma: clinical and experimental concepts Robert James Casson, Glyn Chidlow, John P. M. Wood et al. · Clinical and Experimental Ophthalmology Open access 22 Feb 2012 519
36 Adding Chloroquine to Conventional Treatment for Glioblastoma Multiforme Julio Sotelo, Eduardo Daniel Briceño, Miguel Angel López-González · Annals of Internal Medicine 7 Mar 2006 517
37 Use of arsenic trioxide (As2O3) in the treatment of patients with acute promyelocytic leukemia Guillermo Lazo, Hagop M. Kantarjian, Elihu H. Estey et al. · Cancer 17 Apr 2003 495
38 The clinical features of Leber's hereditary optic neuropathy defined by the presence of a pathogenic mitochondrial DNA mutation Paul Riordan‐Eva, Michael D. Sanders, G.G. Govan et al. · Brain 1995 491
39 Diagnostic Criteria for Graves' Ophthalmopathy George B. Bartley, Colum A. Gorman · American Journal of Ophthalmology Jun 1995 486
40 Intraocular injection of crystalline cortisone as adjunctive treatment of diabetic macular edema Jost Bruno Jonas, Antje Söfker · American Journal of Ophthalmology Sep 2001 482
41 Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases Md. Abdul Alim Al‐Bari · Journal of Antimicrobial Chemotherapy Open access 17 Feb 2015 472
42 Oxidative stress and nerve damage: Role in chemotherapy induced peripheral neuropathy Aparna Areti, Veera Ganesh Yerra, V.G.M. Naidu et al. · Redox Biology Open access 2014 463
43 Paracentral Acute Middle Maculopathy David Sarraf, Ehsan Rahimy, Amani A. Fawzi et al. · JAMA Ophthalmology 9 Aug 2013 463
44 A Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa Michael F. Marmor · Archives of Ophthalmology Nov 1993 462
45 Pseudoexfoliation Syndrome Ocular Manifestation of a Systemic Disorder? Ursula M. Schlötzer-Schrehardt · Archives of Ophthalmology Dec 1992 443
46 Return of Chloroquine Antimalarial Efficacy in Malawi Miriam K. Laufer, Phillip C. Thesing, Nicole D. Eddington et al. · New England Journal of Medicine Open access 8 Nov 2006 442
47 Incidence of Nonarteritic Anteripr Ischemic Optic Neuropathy Matthew G. Hattenhauer, Jacqueline A. Leavitt, David O. Hodge et al. · American Journal of Ophthalmology 1997 440
48 Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial Anne Katrin Sjølie, Ronald Klein, Massimo Porta et al. · The Lancet 26 Sep 2008 435
49 Mechanism of action of hydroxychloroquine as an antirheumatic drug Robert I. Fox · Seminars in Arthritis and Rheumatism Oct 1993 435
50 Focal Myocarditis Associated with Pheochromocytoma Peter D. Van Vliet, Howard B. Burchell, Jack L. Titus · New England Journal of Medicine 19 May 1966 430

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.