Most cited papers in Escherichia coli research studies
What are the most cited papers in Escherichia coli research studies?
The most cited paper in Escherichia coli research studies is "Roary: rapid large-scale prokaryote pan genome analysis" (Andrew J. Page, Carla A. Cummins, Martin B. Hunt et al., 2015), with 6,188 citations. Next come "Pathogenic Escherichia coli" (5,562) and "Diarrheagenic Escherichia coli" (5,032).
Showing 50 of 100 papers. Every paper with more than 893 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Roary: rapid large-scale prokaryote pan genome analysis Andrew J. Page, Carla A. Cummins, Martin B. Hunt et al. · Bioinformatics | 20 Jul 2015 | 6,188 |
| 2 | Pathogenic Escherichia coli James B. Kaper, James P. Nataro, Harry L. T. Mobley · Nature Reviews Microbiology | Feb 2004 | 5,562 |
| 3 | Diarrheagenic Escherichia coli James P. Nataro, James B. Kaper · Clinical Microbiology Reviews | 1998 | 5,032 |
| 4 | Lipopolysaccharide Endotoxins Christian R.H. Raetz, Chris Whitfield · Annual Review of Biochemistry | Jun 2002 | 4,420 |
| 5 | Urinary tract infections: epidemiology, mechanisms of infection and treatment options Ana Lidia Flores‐Mireles, Jennifer N. Walker, Michael G. Caparon et al. · Nature Reviews Microbiology | 8 Apr 2015 | 4,336 |
| 6 | The Bacterial Cell Envelope Thomas J. Silhavy, Daniel E. Kahne, Scott S. Walker · Cold Spring Harbor Perspectives in Biology | 14 Apr 2010 | 3,848 |
| 7 | Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study Karen L. Kotloff et al. · The Lancet | 13 May 2013 | 3,665 |
| 8 | The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 Fumitaka Hayashi, Kelly D. Smith, Adrian Ozinsky et al. · Nature | Apr 2001 | 3,615 |
| 9 | Rapid and Simple Determination of the Escherichia coli Phylogenetic Group Olivier Clermont, Stéphane Bonacorsi, Édouard Bingen · Applied and Environmental Microbiology | Oct 2000 | 2,637 |
| 10 | Bifidobacteria can protect from enteropathogenic infection through production of acetate Shinji Fukuda, Hidehiro Toh, Koji Hase et al. · Nature | 2011 | 2,421 |
| 11 | A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR Virginia L. Miller, John J. Mekalanos · Journal of Bacteriology | Jun 1988 | 2,158 |
| 12 | Genome sequence of enterohaemorrhagic Escherichia coli O157:H7 Nicole T. Perna et al. · Nature | 2001 | 2,075 |
| 13 | Sex and virulence in Escherichia coli : an evolutionary perspective Thierry Wirth, Daniel Falush, Ruiting Lan et al. · Molecular Microbiology | 4 May 2006 | 2,044 |
| 14 | The Epidemiology of Infections Caused by Escherichia coli O157: H7, Other Enterohemorrhagic E. coli, and the Associated Hemolytic Uremic Syndrome Patricia M. Griffin, Robert V. Tauxe · Epidemiologic Reviews | 1991 | 1,824 |
| 15 | Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome Phillip I. Tarr, Carrie A. Gordon, Wayne Leslie Chandler · The Lancet | Mar 2005 | 1,776 |
| 16 | Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens Sirijan Santajit, Nitaya Indrawattana · BioMed Research International | 2016 | 1,684 |
| 17 | CX 3 CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance Jan Hendrik Niess, Stephan Brand, Xiubin Gu et al. · Science | 13 Jan 2005 | 1,603 |
| 18 | The population genetics of commensal Escherichia coli Olivier Tenaillon, David Skurnik, Bertrand Picard et al. · Nature Reviews Microbiology | 16 Feb 2010 | 1,600 |
| 19 | Recent Advances in Understanding Enteric Pathogenic Escherichia coli Matthew A. Croxen, Robyn J. Law, Roland Werner Scholz et al. · Clinical Microbiology Reviews | Oct 2013 | 1,593 |
| 20 | Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli Rodney A. Welch, Valerie D. Burland, Guy Plunkett et al. · Proceedings of the National Academy of Sciences | 5 Dec 2002 | 1,587 |
| 21 | High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease Arlette Darfeuille–Michaud, Jérôme Boudeau, Philippe Bulois et al. · Gastroenterology | Aug 2004 | 1,580 |
| 22 | Homeoviscous Adaptation—A Homeostatic Process that Regulates the Viscosity of Membrane Lipids in Escherichia coli Michael S. Sinensky · Proceedings of the National Academy of Sciences | Feb 1974 | 1,546 |
| 23 | Real-Time Whole-Genome Sequencing for Routine Typing, Surveillance, and Outbreak Detection of Verotoxigenic Escherichia coli Katrine Joensen, Flemming Scheutz, Ole Lund et al. · Journal of Clinical Microbiology | 27 Feb 2014 | 1,480 |
| 24 | The Antibacterial Lectin RegIIIγ Promotes the Spatial Segregation of Microbiota and Host in the Intestine Shipra Vaishnava, Miwako Yamamoto, Kari M. Severson et al. · Science | 13 Oct 2011 | 1,420 |
| 25 | Pathogenesis and Diagnosis of Shiga Toxin-Producing Escherichia coli Infections James C. Paton, Adrienne W. Paton · Clinical Microbiology Reviews | Jul 1998 | 1,419 |
| 26 | Anatomical basis of tolerance and immunity to intestinal antigens Allan McI. Mowat · Nature reviews. Immunology | Apr 2003 | 1,404 |
| 27 | Common themes in microbial pathogenicity revisited B. Brett Finlay, Stanley Falkow · Microbiology and Molecular Biology Reviews | Jun 1997 | 1,374 |
| 28 | An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid Mathias Chamaillard, Masahito Hashimoto, Yasuo Horie et al. · Nature Immunology | 6 Jun 2003 | 1,334 |
| 29 | Gut inflammation provides a respiratory electron acceptor for Salmonella Sebastian Winter, Parameth Thiennimitr, Maria G. Winter et al. · Nature | Sep 2010 | 1,330 |
| 30 | Pathogenicity Islands and the Evolution of Microbes Jörg Hinrich Hacker, James B. Kaper · Annual Review of Microbiology | Oct 2000 | 1,315 |
| 31 | A colony bank containing synthetic CoI EI hybrid plasmids representative of the entire E. coli genome Louise Clarke, John A. Carbon · Cell | Sep 1976 | 1,309 |
| 32 | Infection by verocytotoxin-producing Escherichia coli Mohamed A. Karmali · Clinical Microbiology Reviews | 1989 | 1,294 |
| 33 | Complete Genome Sequence of Enterohemorrhagic Eschelichia coli O157:H7 and Genomic Comparison with a Laboratory Strain K-12 Tetsuya Hayashi · DNA Research | 2001 | 1,294 |
| 34 | Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine Wolfgang Kruis, P Frič, J Pokrotnieks et al. · Gut | 11 Oct 2004 | 1,293 |
| 35 | Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut Nicholas John Mantis, Nicolas Rol, Blaise Corthésy · Mucosal Immunology | 5 Oct 2011 | 1,290 |
| 36 | Extended Virulence Genotypes of Escherichia coli Strains from Patients with Urosepsis in Relation to Phylogeny and Host Compromise James R. Johnson, Adam L. Stell · The Journal of Infectious Diseases | 2000 | 1,283 |
| 37 | ANTIGEN‐ANTIBODY REACTIONS IN GELS Örjan Ouchterlony · Acta Pathologica Microbiologica Scandinavica | Jul 1953 | 1,276 |
| 38 | Epidemiology of Escherichia coli O157:H7 Outbreaks, United States, 1982–2002 Josefa M. Rangel, Phyllis H. Sparling, Collen Crowe et al. · Emerging infectious diseases | Apr 2005 | 1,271 |
| 39 | Global burden of Shigella infections: implications for vaccine development and implementation of control strategies. Karen L. Kotloff, Jonathan P. Winickoff, Bernard Ivanoff et al. · PubMed | 1999 | 1,263 |
| 40 | Shigella flexneri induces apoptosis in infected macrophages Arturo Zychlinsky, M.C. Prévost, Philippe Jean Sansonetti · Nature | Jul 1992 | 1,260 |
| 41 | Virulence factors in Escherichia coli urinary tract infection James R. Johnson · Clinical Microbiology Reviews | 1991 | 1,260 |
| 42 | VANCOMYCIN-RESISTANT ENTEROCOCCI AnneH.C. Uttley, C.H. Collins, Jay Naidoo et al. · The Lancet | 1988 | 1,250 |
| 43 | Escherichia coli that Cause Diarrhea: Enterotoxigenic, Enteropathogenic, Enteroinvasive, Enterohemorrhagic, and Enteroadherent Myron M. Levine · The Journal of Infectious Diseases | Mar 1987 | 1,249 |
| 44 | A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens. T K McDaniel, Karen G. Jarvis, Michael S. Donnenberg et al. · Proceedings of the National Academy of Sciences | 28 Feb 1995 | 1,245 |
| 45 | Molecular mechanisms of Escherichia coli pathogenicity Matthew A. Croxen, B. Brett Finlay · Nature Reviews Microbiology | 7 Dec 2009 | 1,241 |
| 46 | Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths Marie Touchon et al. · PLoS Genetics | 22 Jan 2009 | 1,236 |
| 47 | Population genomics of Klebsiella pneumoniae Kelly L. Wyres, Margaret M. C. Lam, Kathryn E. Holt · Nature Reviews Microbiology | 13 Feb 2020 | 1,226 |
| 48 | Detection and Characterization of Shiga Toxigenic Escherichia coli by Using Multiplex PCR Assays for stx 1 , stx 2 , eaeA , Enterohemorrhagic E. coli hlyA , rfb O111 , and rfb O157 Adrienne W. Paton, James C. Paton · Journal of Clinical Microbiology | Feb 1998 | 1,217 |
| 49 | Genomic islands in pathogenic and environmental microorganisms Ulrich Dobrindt, Bianca Hochhut, Ute Hentschel et al. · Nature Reviews Microbiology | 21 Apr 2004 | 1,205 |
| 50 | Diarrheagenic Escherichia coli Tânia A. T. Gomes, Waldir Pereira Elias, Isabel C. A. Scaletsky et al. · Brazilian Journal of Microbiology | 5 Nov 2016 | 1,190 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.