Most cited papers in Estrogen and related hormone effects
What are the most cited papers in Estrogen and related hormone effects?
The most cited paper in Estrogen and related hormone effects is "Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial" (Writing Group for the Women's Health Initiative Investigators, 2002), with 15,961 citations. Next come "The Steroid and Thyroid Hormone Receptor Superfamily" (7,575) and "The nuclear receptor superfamily: The second decade" (7,017).
Showing 50 of 100 papers. Every paper with more than 1,645 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial Writing Group for the Women's Health Initiative Investigators · JAMA | 17 Jul 2002 | 15,961 |
| 2 | The Steroid and Thyroid Hormone Receptor Superfamily Ronald M. Evans · Science | 13 May 1988 | 7,575 |
| 3 | The nuclear receptor superfamily: The second decade David J. Mangelsdorf, Carl S. Thummel, Miguel Beato et al. · Cell | Dec 1995 | 7,017 |
| 4 | A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer Soonmyung Paik, Steven Shak, Gong Tang et al. · New England Journal of Medicine | 10 Dec 2004 | 6,414 |
| 5 | Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women Stephen B. Hulley · JAMA | 19 Aug 1998 | 6,286 |
| 6 | Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study Bernard Fisher, Joseph P. Costantino, Donald Lawrence Wickerham et al. · JNCI Journal of the National Cancer Institute | 16 Sep 1998 | 5,532 |
| 7 | Breast Cancer Treatment Adrienne Gropper Waks, Eric P. Winer · JAMA | 22 Jan 2019 | 5,015 |
| 8 | Cloning of a novel receptor expressed in rat prostate and ovary. George G. J. M. Kuiper, Eva Enmark, Markku Pelto‐Huikko et al. · Proceedings of the National Academy of Sciences | 11 Jun 1996 | 4,820 |
| 9 | Effects of Conjugated Equine Estrogen in Postmenopausal Women With Hysterectomy The Women's Health Initiative Steering Committee* · JAMA | 14 Apr 2004 | 4,508 |
| 10 | Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β George G. J. M. Kuiper, Bo Carlsson, Kaj Grandien et al. · Endocrinology | Mar 1997 | 4,457 |
| 11 | American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer M. Elizabeth H. Hammond et al. · Journal of Clinical Oncology | 19 Apr 2010 | 4,301 |
| 12 | Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β George G. J. M. Kuiper, Josephine Gabriela Lemmen, Bo Carlsson et al. · Endocrinology | Oct 1998 | 4,209 |
| 13 | Tamoxifen for early breast cancer: an overview of the randomised trials Abe, Osahiko, Bartholomeus, Sylvie, Piccart-Gebhart, Martine · The Lancet | May 1998 | 4,118 |
| 14 | X-Tile Robert L. Camp, Marisa P Dolled-Filhart, David L. Rimm · Clinical Cancer Research | Nov 2004 | 3,979 |
| 15 | Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia M. H. Frick, Olli Elo, Kauko Haapa et al. · New England Journal of Medicine | 12 Nov 1987 | 3,901 |
| 16 | A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis Pere Puigserver, Zhidan Wu, Cheol Won Park et al. · Cell | Mar 1998 | 3,881 |
| 17 | GLUTATHIONE TRANSFERASES John David Hayes, Jack U. Flanagan, Ian R. Jowsey · The Annual Review of Pharmacology and Toxicology | 2 Nov 2004 | 3,565 |
| 18 | Molecular basis of agonism and antagonism in the oestrogen receptor Andrzej Marek Brzozowski, Ashley C. W. Pike, Zbigniew Dauter et al. · Nature | Oct 1997 | 3,370 |
| 19 | The RXR heterodimers and orphan receptors David J. Mangelsdorf, Ronald M. Evans · Cell | Dec 1995 | 3,195 |
| 20 | Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs Turk Rhen, John Anthony Cidlowski · New England Journal of Medicine | 20 Oct 2005 | 3,178 |
| 21 | The Protective Effects of Estrogen on the Cardiovascular System Michael E. Mendelsohn, Richard H. Karas · New England Journal of Medicine | 10 Jun 1999 | 3,115 |
| 22 | Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials Early Breast Cancer Trialists' Collaborative Group (EBCTCG) · The Lancet | Aug 2011 | 3,114 |
| 23 | Cyclooxygenases: Structural, Cellular, and Molecular Biology William Lee Smith, David L. DeWitt, R. Michael Garavito · Annual Review of Biochemistry | Jun 2000 | 2,933 |
| 24 | A decade of molecular biology of retinoic acid receptors Pierre Chambon · The FASEB Journal | Jul 1996 | 2,899 |
| 25 | The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen Andrew K. Shiau, Danielle Barstad, Paula M. Loria et al. · Cell | Dec 1998 | 2,750 |
| 26 | CYCLOOXYGENASES 1 AND 2 John Robert Vane, Y.S. Bakhle, Renia M. Botting · The Annual Review of Pharmacology and Toxicology | Apr 1998 | 2,744 |
| 27 | Cyclooxygenase in biology and disease Raymond N. DuBois, Steven B. Abramson, Leslie J. Crofford et al. · The FASEB Journal | Sep 1998 | 2,519 |
| 28 | Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man Eric P. Smith, Jeff A. Boyd, Graeme R. Frank et al. · New England Journal of Medicine | 20 Oct 1994 | 2,498 |
| 29 | Differential oestrogen receptor binding is associated with clinical outcome in breast cancer Caryn S. Ross-Innes, Rory Stark, Andrew Erich Teschendorff et al. · Nature | 2012 | 2,434 |
| 30 | Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis Nathalie Auphan‐Anezin, Joseph A. DiDonato, Caridad Rosette et al. · Science | 13 Oct 1995 | 2,425 |
| 31 | Prostanoid Receptors: Structures, Properties, and Functions Shuh Narumiya, Yukihiko Sugimoto, Fumitaka Ushikubi · Physiological Reviews | 10 Jan 1999 | 2,419 |
| 32 | Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily Sergio A. Oñate, Sophia Y. Tsai, Ming‐Jer Tsai et al. · Science | 24 Nov 1995 | 2,418 |
| 33 | Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2) Masanobu Oshima, Joseph E. Dinchuk, Stacia Kargman et al. · Cell | Nov 1996 | 2,374 |
| 34 | Hormone Therapy To Prevent Disease and Prolong Life in Postmenopausal Women Deborah Grady, Susan M. Rubin, Diana B. Petitti et al. · Annals of Internal Medicine | 15 Dec 1992 | 2,369 |
| 35 | Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer Chris Tran, Samedy Ouk, Nicola J. Clegg et al. · Science | 9 Apr 2009 | 2,341 |
| 36 | A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling Chetana M. Revankar, Daniel F. Cimino, Larry A. Sklar et al. · Science | 10 Feb 2005 | 2,306 |
| 37 | Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer Anthony Howell, Jack M. Cuzick, Michael Baum et al. · The Lancet | 2005 | 2,295 |
| 38 | Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells Masahiko Tsujii, Sunao Kawano, Shingo Tsuji et al. · Cell | May 1998 | 2,293 |
| 39 | Molecular determinants of resistance to antiandrogen therapy Charlie D. Chen, Derek S. Welsbie, Chris Tran et al. · Nature Medicine | 21 Dec 2003 | 2,291 |
| 40 | Bile Acids: Natural Ligands for an Orphan Nuclear Receptor Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe et al. · Science | 21 May 1999 | 2,273 |
| 41 | Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer Maggie C.U. Cheang, Stephen Chia, David K. Voduc et al. · JNCI Journal of the National Cancer Institute | 12 May 2009 | 2,257 |
| 42 | The coregulator exchange in transcriptional functions of nuclear receptors Christopher K. Glass, Michael G. Rosenfeld · Genes & Development | 15 Jan 2000 | 2,253 |
| 43 | A human retinoic acid receptor which belongs to the family of nuclear receptors Martin P. Petkovich, Nigel J. Brand, Andrée Krust et al. · Nature | Dec 1987 | 2,245 |
| 44 | Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation Mitsuhiro Watanabe, Sander M. Houten, Chikage Mataki et al. · Nature | 2006 | 2,230 |
| 45 | A signature motif in transcriptional co-activators mediates binding to nuclear receptors David M. Heery, Eric Kalkhoven, Susan Hoare et al. · Nature | 12 Jun 1997 | 2,163 |
| 46 | Distribution of androgen and estrogen receptor mRNA‐containing cells in the rat brain: An in situ hybridization study Richard B. Simerly, Larry W. Swanson, Chihway Chang et al. · The Journal of Comparative Neurology | Apr 1990 | 2,138 |
| 47 | Estrogen Receptor Status by Immunohistochemistry Is Superior to the Ligand-Binding Assay for Predicting Response to Adjuvant Endocrine Therapy in Breast Cancer Jennet M. Harvey, Gary M. Clark, Charles Kent Osborne et al. · Journal of Clinical Oncology | May 1999 | 2,084 |
| 48 | Estrogen plus Progestin and the Risk of Coronary Heart Disease JoAnn E. Manson, Judith A. Hsia, Karen Johnson et al. · New England Journal of Medicine | 6 Aug 2003 | 2,077 |
| 49 | Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial Christina Davies et al. · The Lancet | 5 Dec 2012 | 2,067 |
| 50 | Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor Andreas Hörlein, Anders M. Näär, Thorsten Heinzel et al. · Nature | Oct 1995 | 2,065 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.