Science Explorer Back to mapMap
Discussion
Topic · Genetics

Estrogen and related hormone effects

Estrogen and related hormone effects is a research topic within Genetics. Science Explorer counts 62k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the mechanisms of estrogen receptor signaling, with a focus on its role in breast cancer, interactions with glucocorticoids, and the effects of various drugs such as tamoxifen and aromatase inhibitors. It delves into the molecular pathways, gene regulation, and coactivator/coregulator dynamics involved in estrogen signaling.

  • Estrogen
  • Receptor
  • Signaling
  • Breast Cancer
  • Glucocorticoids
  • Nuclear Receptors
  • Tamoxifen
  • Aromatase Inhibitors
  • G Protein-Coupled Receptor
  • Transcriptional Regulation
Research works
62k
fractional, since 1950
In the world top 10%
6.3k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-10%
the tick is no change
Largest producer
United States
38% of the 10 largest, 2022-now
Estrogen and related hormone effects

Which countries lead Estrogen and related hormone effects research?

By volume, the United States and China publish the most (1.3k and 743 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.3k works
  2. 2 China 743 works
  3. 3 India 278 works
  4. 4 Japan 176 works
  5. 5 United Kingdom 174 works
  6. 6 Italy 163 works
  7. 7 Germany 163 works
  8. 8 South Korea 125 works
  9. 9 France 116 works
  10. 10 Russia 113 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 38.4%China: 22.3%India: 8.3%Japan: 5.3%6 others listed: 25.6%38%largest
United States1,281 · 38.4%China743 · 22.3%India278 · 8.3%Japan176 · 5.3%6 others listed854 · 25.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Estrogen and related hormone effects research?

By volume in 2022-now, Harvard University publishes the most Estrogen and related hormone effects research, followed by Mayo Clinic and University of North Carolina at Chapel Hill.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 48 works
  2. 2 Mayo ClinicUnited States 33 works
  3. 3 University of North Carolina at Chapel HillUnited States 32 works
  4. 4 National Institutes of HealthUnited States 31 works
  5. 5 Russian Academy of SciencesRussia 26 works
  6. 6 InsermFrance 22 works
  7. 7 Wenzhou Medical UniversityChina 22 works
  8. 8 Centre National de la Recherche ScientifiqueFrance 22 works
  9. 9 The University of Texas MD Anderson Cancer CenterUnited States 21 works
  10. 10 Baylor College of MedicineUnited States 18 works

Who are the leading researchers in Estrogen and related hormone effects?

The most-cited researchers publishing on Estrogen and related hormone effects include George Davey Smith, Walter Churchill Willett and Mark J. Daly.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Walter Churchill Willett United States 411k citations
  3. 3 Mark J. Daly United States 403k citations
  4. 4 Guido Kroemer France 386k citations
  5. 5 Gad A. Getz United States 364k citations
  6. 6 Elaine R. Mardis United States 346k citations
  7. 7 Hermann Brenner Germany 343k citations
  8. 8 Shizuo Akira Japan 342k citations
  9. 9 Cyrus Cooper United Kingdom 342k citations
  10. 10 Jun Wang China 340k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Estrogen and related hormone effects?

The most cited paper in Estrogen and related hormone effects is "Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial" (Writing Group for the Women's Health Initiative Investigators, 2002), with 15,961 citations. Next come "The Steroid and Thyroid Hormone Receptor Superfamily" (7,575) and "The nuclear receptor superfamily: The second decade" (7,017).

Most cited papers
#PaperReleasedCitations
1 Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial Writing Group for the Women's Health Initiative Investigators · JAMA Open access 17 Jul 2002 15,961
2 The Steroid and Thyroid Hormone Receptor Superfamily Ronald M. Evans · Science Open access 13 May 1988 7,575
3 The nuclear receptor superfamily: The second decade David J. Mangelsdorf, Carl S. Thummel, Miguel Beato et al. · Cell Open access Dec 1995 7,017
4 A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer Soonmyung Paik, Steven Shak, Gong Tang et al. · New England Journal of Medicine Open access 10 Dec 2004 6,414
5 Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women Stephen B. Hulley · JAMA 19 Aug 1998 6,286
All 100 most cited papers, with filters and sorting

Where is Estrogen and related hormone effects research done?

The largest centres of Estrogen and related hormone effects research in 2022-now are Beijing (China), Seoul (South Korea), Moscow (Russia) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in Wenzhou.

Largest cities, 2022-now

  1. 1 BeijingChina 83 works
  2. 2 SeoulSouth Korea 72 works
  3. 3 MoscowRussia 64 works
  4. 4 ShanghaiChina 62 works
  5. 5 New YorkUnited States 62 works
  6. 6 LondonUnited Kingdom 55 works
  7. 7 ParisFrance 50 works
  8. 8 HoustonUnited States 49 works
  9. 9 GuangzhouChina 46 works
  10. 10 TokyoJapan 46 works

Where it is the local speciality

  1. WenzhouCN · 23.1 works5.5×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Estrogen and related hormone effects than the world average.

See Estrogen and related hormone effects on the map

Where is the best place to study Estrogen and related hormone effects?

Among universities, judged by research, Harvard University, University of Southern California and Cornell University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 16%fractional works in this field (log) →share of work in the world top 10% →Harvard UniversityUniversity of Southe…Cornell UniversityKarolinska Institutet
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 90.124.9%3.6×48 +16.7%
2University of Southern CaliforniaUnited States 65.222.3%4.2×15 +43.5%
3Cornell UniversityUnited States 64.120.9%3.1×17 +31.7%
4Karolinska InstitutetSweden 55.811.4%6.9×16 -6.4%
5Wenzhou Medical UniversityChina 55.213.0%10.4×22 +148.9%
6Duke UniversityUnited States 54.420.9%2.7×9 +4.6%
7Baylor College of MedicineUnited States 51.910.3%8.6×18 -31.1%
8Vanderbilt UniversityUnited States 51.96.0%5.3×16 +59.1%
9University of WashingtonUnited States 49.818.5%1.9×9 +10.4%
10University of BernSwitzerland 48.511.8%5.7×13 +45.3%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Estrogen and related hormone effects, country by country

Is Estrogen and related hormone effects research growing?

Output in 2022-2025 was 10% lower than in 2018-2021, peaking in 2009.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Estrogen and related hormone effects as a percentage of every work published that year, 0.020% in 2024.

still counting0.050%0.10%0.15%Estrogen and related hormone effects0.020% in 202519801990200020102020

Fractional works of Estrogen and related hormone effects over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Estrogen and related hormone effects10.3% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

Ask a question or share a note about Estrogen and related hormone effects. Posts are plain text and can be reported.