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Topic · Genetics

Digestive system and related health

Digestive system and related health is a research topic within Genetics. Science Explorer counts 27k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the genetic adaptation of lactase persistence in humans, focusing on the role of CDX2 expression, intestinal differentiation, and its implications for milk consumption, lactose intolerance, evolutionary genetics, and associated health conditions such as colon cancer, gastric metaplasia, and bone health.

  • Lactase Persistence
  • Genetic Adaptation
  • Intestinal Differentiation
  • CDX2 Expression
  • Lactose Intolerance
  • Evolutionary Genetics
  • Milk Consumption
  • Colon Cancer
  • Gastric Metaplasia
  • Bone Health
Research works
27k
fractional, since 1950
In the world top 10%
2.7k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+6%
the tick is no change
Largest producer
China
26% of the 10 largest, 2022-now
Digestive system and related health

Which countries lead Digestive system and related health research?

By volume, China and the United States publish the most (588 and 533 works in 2022-now).

By volume, 2022-now

  1. 1 China 588 works
  2. 2 United States 533 works
  3. 3 Russia 202 works
  4. 4 India 189 works
  5. 5 Brazil 174 works
  6. 6 Germany 142 works
  7. 7 Italy 118 works
  8. 8 Japan 118 works
  9. 9 United Kingdom 94 works
  10. 10 Spain 93 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 26.1%United States: 23.7%Russia: 9.0%India: 8.4%6 others listed: 32.8%26%largest
China588 · 26.1%United States533 · 23.7%Russia202 · 9.0%India189 · 8.4%6 others listed739 · 32.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead Digestive system and related health research?

By volume in 2022-now, Russian Academy of Sciences publishes the most Digestive system and related health research, followed by Nanchang University and Jiangnan University.

By volume, 2022-now

  1. 1 Russian Academy of SciencesRussia 34 works
  2. 2 Nanchang UniversityChina 22 works
  3. 3 Jiangnan UniversityChina 21 works
  4. 4 Harvard UniversityUnited States 16 works
  5. 5 Institut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementFrance 16 works
  6. 6 Chinese Academy of Agricultural SciencesChina 13 works
  7. 7 Zhejiang UniversityChina 13 works
  8. 8 Centre National de la Recherche ScientifiqueFrance 12 works
  9. 9 InsermFrance 11 works
  10. 10 Shanghai Jiao Tong UniversityChina 11 works

Who are the leading researchers in Digestive system and related health?

The most-cited researchers publishing on Digestive system and related health include Eric S. Lander, Rob Knight and George Davey Smith.

  1. 1 Eric S. Lander United States 524k citations
  2. 2 Rob Knight United States 468k citations
  3. 3 George Davey Smith United Kingdom 435k citations
  4. 4 Walter Churchill Willett United States 411k citations
  5. 5 Richard M. Durbin United Kingdom 410k citations
  6. 6 Mark J. Daly United States 403k citations
  7. 7 Stacey L. Gabriel United States 402k citations
  8. 8 Peer Bork Germany 396k citations
  9. 9 Guido Kroemer France 386k citations
  10. 10 Bert Vogelstein United States 373k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Digestive system and related health?

The most cited paper in Digestive system and related health is "The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells" (Sendurai A. Mani, Wenjun Guo, Mai-Jing Liao et al., 2008), with 8,810 citations. Next come "Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics" (7,690) and "Identification of stem cells in small intestine and colon by marker gene Lgr5" (5,813).

Most cited papers
#PaperReleasedCitations
1 The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells Sendurai A. Mani, Wenjun Guo, Mai-Jing Liao et al. · Cell Open access May 2008 8,810
2 Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics Glenn R. Gibson, Marcel B. Roberfroid · Journal of Nutrition Jun 1995 7,690
3 Identification of stem cells in small intestine and colon by marker gene Lgr5 Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature Oct 2007 5,813
4 Lessons from Hereditary Colorectal Cancer Kenneth W. Kinzler, Bert Vogelstein · Cell Open access Oct 1996 4,949
5 Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria Ivaylo I. Ivanov, Koji Atarashi, Nicolas Manel et al. · Cell Open access Oct 2009 4,598
All 99 most cited papers, with filters and sorting

Where is Digestive system and related health research done?

The largest centres of Digestive system and related health research in 2022-now are Moscow (Russia), Beijing (China), Wuxi (China) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in Wuxi.

Largest cities, 2022-now

  1. 1 MoscowRussia 80 works
  2. 2 BeijingChina 75 works
  3. 3 WuxiChina 40 works
  4. 4 ShanghaiChina 36 works
  5. 5 ParisFrance 35 works
  6. 6 TokyoJapan 31 works
  7. 7 SeoulSouth Korea 28 works
  8. 8 MadridSpain 28 works
  9. 9 São PauloBrazil 28 works
  10. 10 LondonUnited Kingdom 27 works

Where it is the local speciality

  1. WuxiCN · 40.2 works12×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Digestive system and related health than the world average.

See Digestive system and related health on the map

Where is the best place to study Digestive system and related health?

Among universities, judged by research, Nanchang University, Jiangnan University and Harvard University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 19.82%fractional works in this field (log) →share of work in the world top 10% →Nanchang UniversityJiangnan UniversityKU LeuvenHarvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Nanchang UniversityChina 90.830.9%9.7×22 +243.4%
2Jiangnan UniversityChina 87.329.1%11.5×21 +281.1%
3Harvard UniversityUnited States 58.817.7%1.7×16 -18.2%
4KU LeuvenBelgium 57.527.1%2.9×8 +37.9%
5Wageningen University & ResearchNetherlands 57.419.5%7.5×8 +52.3%
6Zhejiang UniversityChina 54.324.0%1.5×13 +83.9%
7China Agricultural UniversityChina 49.117.3%5.7×10 +86.3%
8Cornell UniversityUnited States 42.311.2%2.4×10 +39.7%
9University of California, DavisUnited States 41.516.8%3.4×8 -4.2%
10Johns Hopkins UniversityUnited States 34.84.6%1.8×8 +40.2%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Digestive system and related health, country by country

Is Digestive system and related health research growing?

Output in 2022-2025 was 6% higher than in 2018-2021, peaking in 2024. The fastest-growing topics are Digestive system and related health.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Digestive system and related health as a percentage of every work published that year, 0.018% in 2024.

still counting0.025%0.050%0.075%Digestive system and related health0.016% in 202519801990200020102020

Fractional works of Digestive system and related health over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Digestive system and related health10.3% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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