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Topic · Genetics

Inflammatory Bowel Disease

Inflammatory Bowel Disease is a research topic within Genetics. Science Explorer counts 39k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the genetics, epidemiology, pathogenesis, and treatment of inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. It covers topics such as host-microbe interactions, genetic susceptibility loci, immune system involvement, therapeutic targets, and the global burden of these diseases.

  • Inflammatory Bowel Disease
  • Crohn's Disease
  • Ulcerative Colitis
  • Genetics
  • Immunology
  • Therapies
  • Epidemiology
  • Pathogenesis
  • Biological Therapies
  • Mucosal Healing
Research works
39k
fractional, since 1950
In the world top 10%
3.9k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+29%
the tick is no change
Largest producer
United States
27% of the 10 largest, 2022-now
Inflammatory Bowel Disease

Which countries lead Inflammatory Bowel Disease research?

By volume, the United States and China publish the most (2.2k and 2.2k works in 2022-now).

By volume, 2022-now

  1. 1 United States 2.2k works
  2. 2 China 2.2k works
  3. 3 United Kingdom 728 works
  4. 4 Italy 523 works
  5. 5 Japan 471 works
  6. 6 Canada 463 works
  7. 7 Spain 432 works
  8. 8 Germany 383 works
  9. 9 France 306 works
  10. 10 India 276 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 27.5%China: 27.3%United Kingdom: 9.2%Italy: 6.6%6 others listed: 29.4%27%largest
United States2,174 · 27.5%China2,157 · 27.3%United Kingdom728 · 9.2%Italy523 · 6.6%6 others listed2,330 · 29.4%

Shares of the rows listed above, not of the whole node.

Which institutions lead Inflammatory Bowel Disease research?

By volume in 2022-now, Sun Yat-sen University publishes the most Inflammatory Bowel Disease research, followed by Tel Aviv University and Harvard University.

By volume, 2022-now

  1. 1 Sun Yat-sen UniversityChina 110 works
  2. 2 Tel Aviv UniversityIsrael 104 works
  3. 3 Harvard UniversityUnited States 101 works
  4. 4 Mount Sinai Health SystemUnited States 97 works
  5. 5 Mayo ClinicUnited States 81 works
  6. 6 Zhejiang UniversityChina 78 works
  7. 7 Cleveland ClinicUnited States 74 works
  8. 8 InsermFrance 71 works
  9. 9 University of TorontoCanada 70 works
  10. 10 University of North Carolina at Chapel HillUnited States 68 works

Who are the leading researchers in Inflammatory Bowel Disease?

The most-cited researchers publishing on Inflammatory Bowel Disease include Douglas G. Altman, Eric S. Lander and Rob Knight.

  1. 1 Douglas G. Altman United Kingdom 862k citations
  2. 2 Eric S. Lander United States 524k citations
  3. 3 Rob Knight United States 468k citations
  4. 4 George Davey Smith United Kingdom 435k citations
  5. 5 Walter Churchill Willett United States 411k citations
  6. 6 Mark J. Daly United States 403k citations
  7. 7 Stacey L. Gabriel United States 402k citations
  8. 8 Hermann Brenner Germany 343k citations
  9. 9 Cyrus Cooper United Kingdom 342k citations
  10. 10 Jun Wang China 340k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Inflammatory Bowel Disease?

The most cited paper in Inflammatory Bowel Disease is "Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies" (Siew C. Ng, Hai Yun Shi, Nima Hamidi et al., 2017), with 6,147 citations. Next come "Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease" (5,631) and "A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease" (5,051).

Most cited papers
#PaperReleasedCitations
1 Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies Siew C. Ng, Hai Yun Shi, Nima Hamidi et al. · The Lancet Review 16 Oct 2017 6,147
2 Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease Jean‐Pierre Hugot, Mathias Chamaillard, Habib Zouali et al. · Nature May 2001 5,631
3 A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease Yasunori Ogura, Denise K. Bonen, Naohiro Inohara et al. · Nature Open access May 2001 5,051
4 Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease Luke Jostins et al. · Nature Open access106 authors 31 Oct 2012 4,928
5 Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review Natalie A. Molodecky, Ing Shian Soon, Doreen M. Rabi et al. · Gastroenterology Review 17 Oct 2011 4,874
All 99 most cited papers, with filters and sorting

Where is Inflammatory Bowel Disease research done?

The largest centres of Inflammatory Bowel Disease research in 2022-now are London (United Kingdom), New York (United States), Guangzhou (China) and Beijing (China).

Largest cities, 2022-now

  1. 1 LondonUnited Kingdom 239 works
  2. 2 New YorkUnited States 218 works
  3. 3 GuangzhouChina 210 works
  4. 4 BeijingChina 204 works
  5. 5 ShanghaiChina 164 works
  6. 6 TokyoJapan 141 works
  7. 7 NanjingChina 140 works
  8. 8 HangzhouChina 139 works
  9. 9 SeoulSouth Korea 138 works
  10. 10 ClevelandUnited States 115 works
See Inflammatory Bowel Disease on the map

Where is the best place to study Inflammatory Bowel Disease?

Among universities, judged by research, University College Cork, Aalborg University and University of Chicago score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 16.26%fractional works in this field (log) →share of work in the world top 10% →University College C…Aalborg UniversityUniversity of ChicagoUniversity of Copenh…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1University College CorkIreland 70.830.0%5.4×16 +86.7%
2Aalborg UniversityDenmark 70.723.2%4.6×26 +188.9%
3University of ChicagoUnited States 68.415.5%7.6×63 +22.9%
4University of CopenhagenDenmark 67.512.9%4.8×44 +56.9%
5Vita-Salute San Raffaele UniversityItaly 67.221.5%18.8×23 -
6Sun Yat-sen UniversityChina 67.011.7%5.4×110 +78.5%
7Humanitas UniversityItaly 66.318.4%26.6×38 +0.1%
8Tel Aviv UniversityIsrael 66.26.2%13.3×104 +25.0%
9Harvard UniversityUnited States 65.811.9%3.2×101 -7.0%
10University of CalgaryCanada 65.211.3%9.0×60 +10.3%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Inflammatory Bowel Disease, country by country

Is Inflammatory Bowel Disease research growing?

Output in 2022-2025 was 29% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Inflammatory Bowel Disease.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Inflammatory Bowel Disease as a percentage of every work published that year, 0.046% in 2024.

still counting0.020%0.040%0.060%Inflammatory Bowel Disease0.048% in 202519801990200020102020

Fractional works of Inflammatory Bowel Disease over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Inflammatory Bowel Disease9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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