Topic · Ethics in Clinical Research
Most cited papers in Ethics in Clinical Research
What are the most cited papers in Ethics in Clinical Research?
The most cited paper in Ethics in Clinical Research is "SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials" (A.-W. Chan, Jennifer Tetzlaff, Peter Christian Gøtzsche et al., 2013), with 7,135 citations. Next come "The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research" (6,005) and "The global landscape of AI ethics guidelines" (5,935).
Showing 50 of 97 papers. Every paper with more than 749 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials A.-W. Chan, Jennifer Tetzlaff, Peter Christian Gøtzsche et al. · BMJ | 9 Jan 2013 | 7,135 |
| 2 | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research Nathalie Percie du Sert et al. · PLoS Biology | 14 Jul 2020 | 6,005 |
| 3 | The global landscape of AI ethics guidelines Anna Jobin, Marcello Ienca, Effy Vayena · Nature Machine Intelligence | 2 Sep 2019 | 5,935 |
| 4 | Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials Klaus‐Peter Schulz · JAMA | Feb 1995 | 5,589 |
| 5 | Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? David Moher, Ba’ Pham, Alison Jones et al. · The Lancet | Aug 1998 | 3,611 |
| 6 | The ethics of algorithms: Mapping the debate Brent Mittelstadt, Patrick Allo, Mariarosaria Taddeo et al. · Big Data & Society | Dec 2016 | 3,394 |
| 7 | Sampling in Interview-Based Qualitative Research: A Theoretical and Practical Guide Oliver C. Robinson · Qualitative Research in Psychology | 18 Nov 2013 | 3,268 |
| 8 | Publication bias in clinical research Philippa Easterbrook, Radha S. Gopalan, Jesse A. Berlin et al. · The Lancet | Apr 1991 | 3,156 |
| 9 | ChatGPT Utility in Healthcare Education, Research, and Practice: Systematic Review on the Promising Perspectives and Valid Concerns Malik Sallam · Healthcare | 19 Mar 2023 | 2,928 |
| 10 | Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 Nathalie Percie du Sert et al. · PLoS Biology | 14 Jul 2020 | 2,875 |
| 11 | Artificial intelligence in healthcare Kun‐Hsing Yu, Andrew L. Beam, Isaac S. Kohane · Nature Biomedical Engineering | 5 Oct 2018 | 2,799 |
| 12 | Design and analysis of pilot studies: recommendations for good practice Gillian Lancaster, Susanna R. Dodd, Paula Ruth Williamson · Journal of Evaluation in Clinical Practice | May 2004 | 2,741 |
| 13 | The Belmont Report: ethical principles and guidelines for the protection of human subjects of research Sue Eckstein · Cambridge University Press eBooks | 20 Feb 2003 | 2,712 |
| 14 | What Makes Clinical Research Ethical? Ezekiel J. Emanuel · JAMA | 24 May 2000 | 2,701 |
| 15 | Series: Practical guidance to qualitative research. Part 3: Sampling, data collection and analysis Albine Moser, Irene Korstjens · European Journal of General Practice | 4 Dec 2017 | 2,552 |
| 16 | Equipoise and the Ethics of Clinical Research Benjamin Freedman · New England Journal of Medicine | 16 Jul 1987 | 2,359 |
| 17 | Data, disease and diplomacy: GISAID's innovative contribution to global health Stefan Elbe, Gemma Buckland‐Merrett · Global Challenges | 2017 | 2,318 |
| 18 | A scoping review on the conduct and reporting of scoping reviews Andrea C. Tricco, Erin Lillie, Wasifa Zarin et al. · BMC Medical Research Methodology | 8 Feb 2016 | 2,311 |
| 19 | Underrepresentation of Patients 65 Years of Age or Older in Cancer-Treatment Trials Laura Fulper Hutchins, Joseph M. Unger, John J. Crowley et al. · New England Journal of Medicine | 30 Dec 1999 | 2,203 |
| 20 | The NIH Human Microbiome Project The NIH HMP Working Group et al. · Genome Research | 9 Oct 2009 | 2,103 |
| 21 | The “Meaningful Use” Regulation for Electronic Health Records David Blumenthal, Marilyn Tavenner · New England Journal of Medicine | 13 Jul 2010 | 2,103 |
| 22 | Participation in Cancer Clinical Trials Vivek H. Murthy, Harlan M. Krumholz, Cary Philip Gross · JAMA | 8 Jun 2004 | 2,098 |
| 23 | The Third Wave of Science Studies Harry M. Collins, Robert Evans · Social Studies of Science | Apr 2002 | 2,092 |
| 24 | Genomics is failing on diversity Alice B. Popejoy, Stephanie Malia Fullerton · Nature | 10 Oct 2016 | 2,069 |
| 25 | How Many Scientists Fabricate and Falsify Research? A Systematic Review and Meta-Analysis of Survey Data Daniele Fanelli · PLoS ONE | 28 May 2009 | 1,972 |
| 26 | Antibiotic Resistance Genes as Emerging Contaminants: Studies in Northern Colorado Amy J. Pruden, Ruoting Pei, Heather N. Storteboom et al. · Environmental Science & Technology | 15 Aug 2006 | 1,963 |
| 27 | Participation Rates in Epidemiologic Studies Sandro Galea, Melissa Tracy · Annals of Epidemiology | 7 Jun 2007 | 1,957 |
| 28 | Increasing response rates to postal questionnaires: systematic review Phil J Edwards, Ian Roberts, Mike Clarke et al. · BMJ | 18 May 2002 | 1,950 |
| 29 | Ethics and Clinical Research Henry K. Beecher · New England Journal of Medicine | 16 Jun 1966 | 1,919 |
| 30 | Implementing Machine Learning in Health Care — Addressing Ethical Challenges Danton S. Char, Nigam Haresh Shah, David Christopher Magnus · New England Journal of Medicine | 14 Mar 2018 | 1,828 |
| 31 | Principles alone cannot guarantee ethical AI Brent Mittelstadt · Nature Machine Intelligence | 4 Nov 2019 | 1,825 |
| 32 | Hidden in Plain Sight — Reconsidering the Use of Race Correction in Clinical Algorithms Darshali A. Vyas, Leo G. Eisenstein, David Shumway Jones · New England Journal of Medicine | 17 Jun 2020 | 1,747 |
| 33 | Positive Outcomes Influence the Rate and Time to Publication, but Not the Impact Factor of Publications of Clinical Trial Results Pilar Suñé, Josep María Suñé, J. Bruno Montoro · PLoS ONE | 30 Jan 2013 | 1,713 |
| 34 | A Systematic Review of Barriers and Facilitators to Minority Research Participation Among African Americans, Latinos, Asian Americans, and Pacific Islanders Sheba George, Nelida Duran, Keith C. Norris · American Journal of Public Health | 12 Dec 2013 | 1,640 |
| 35 | Updated Guidance on the Reporting of Race and Ethnicity in Medical and Science Journals Annette Flanagin, Tracy Frey, Stacy L. Christiansen · JAMA | 17 Aug 2021 | 1,628 |
| 36 | The Practice of Nursing Research: Conduct, Critique and Utilization Janet Cozad · AORN Journal | Jun 1989 | 1,579 |
| 37 | Reaching the hard-to-reach: a systematic review of strategies for improving health and medical research with socially disadvantaged groups Billie Bonevski, Madeleine Randell, Christine Louise Paul et al. · BMC Medical Research Methodology | 25 Mar 2014 | 1,537 |
| 38 | Privacy in the age of medical big data W. Nicholson Price, Ivan Glenn Cohen · Nature Medicine | 19 Dec 2018 | 1,529 |
| 39 | A pragmatic–explanatory continuum indicator summary (PRECIS): a tool to help trial designers Kevin E. Thorpe, Merrick Zwarenstein, Andrew David Oxman et al. · Journal of Clinical Epidemiology | 7 Apr 2009 | 1,415 |
| 40 | Perceptions and Experiences of Research Participants on Gender-Based Violence Community Based Survey: Implications for Ethical Guidelines Yandisa Msimelelo Sikweyiya, Rachel K. Jewkes · PLoS ONE | 27 Apr 2012 | 1,335 |
| 41 | Ensuring Fairness in Machine Learning to Advance Health Equity Alvin Rajkomar, Michaela Hardt, Michael D Howell et al. · Annals of Internal Medicine | 3 Dec 2018 | 1,331 |
| 42 | Central Challenges Facing the National Clinical Research Enterprise Nancy S. Sung, William F. Crowley, Myron Genel et al. · JAMA | 12 Mar 2003 | 1,247 |
| 43 | Do no harm: a roadmap for responsible machine learning for health care Jenna Wiens, Suchi Saria, Mark Sendak et al. · Nature Medicine | 19 Aug 2019 | 1,233 |
| 44 | EFFECTIVE RECRUITMENT AND RETENTION OF MINORITY RESEARCH PARTICIPANTS Antronette K. Yancey, Alexander N. Ortega, Shiriki Kumanyika · Annual Review of Public Health | 21 Sep 2005 | 1,224 |
| 45 | More than Tuskegee: Understanding Mistrust about Research Participation Darcell P. Scharff, Katherine J. Mathews, Pamela Braboy Jackson et al. · Journal of Health Care for the Poor and Underserved | Aug 2010 | 1,209 |
| 46 | Continental-scale pollution of estuaries with antibiotic resistance genes Yong‐Guan Zhu, Yi Zhao, Bing Jhang Li et al. · Nature Microbiology | 30 Jan 2017 | 1,201 |
| 47 | Explanatory and pragmatic attitudes in therapeutical trials DANIEL B. SCHWARTZ, J Lellouch · Journal of Chronic Diseases | Aug 1967 | 1,198 |
| 48 | The Construction of Lay Expertise: AIDS Activism and the Forging of Credibility in the Reform of Clinical Trials Steven Epstein · Science Technology & Human Values | Oct 1995 | 1,184 |
| 49 | Trial sequential analysis reveals insufficient information size and potentially false positive results in many meta-analyses Jesper Sune Brok, Kristian Thorlund, Christian Nyfeldt Gluud et al. · Journal of Clinical Epidemiology | 15 Apr 2008 | 1,182 |
| 50 | Observational Health Data Sciences and Informatics (OHDSI): Opportunities for Observational Researchers George M. Hripcsak, Jon D Duke, Nigam Haresh Shah et al. · Studies in health technology and informatics | 2015 | 1,174 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.