Most cited papers in Fibroblast Growth Factor Research
What are the most cited papers in Fibroblast Growth Factor Research?
The most cited paper in Fibroblast Growth Factor Research is "A modified uronic acid carbazole reaction" (Thomas Bitter, H. M. Muir, 1962), with 6,285 citations. Next come "Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial" (5,578) and "The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis" (5,248).
Showing 50 of 100 papers. Every paper with more than 925 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | A modified uronic acid carbazole reaction Thomas Bitter, H. M. Muir · Analytical Biochemistry | Oct 1962 | 6,285 |
| 2 | Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial Masatoshi Kudo et al. · The Lancet | Mar 2018 | 5,578 |
| 3 | The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis Patrick Henry Maxwell, Michael Sean Wiesener, Gin-Wen Chang et al. · Nature | May 1999 | 5,248 |
| 4 | HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing Mircea Ivan, Keiichi Kondo, Haifeng Yang et al. · Science | 20 Apr 2001 | 4,757 |
| 5 | The biology and function of fibroblasts in cancer Raghu K. Kalluri · Nature reviews. Cancer | 23 Aug 2016 | 4,462 |
| 6 | Osteoblastic cells regulate the haematopoietic stem cell niche Laura Maria Calvi, Gary B. Adams, Kathryn W. Weibrecht et al. · Nature | Oct 2003 | 3,462 |
| 7 | Functional polarization of tumour-associated macrophages by tumour-derived lactic acid Oscar R. Colegio, Ngoc-Quynh Chu, Alison L. Szabo et al. · Nature | 11 Jul 2014 | 3,057 |
| 8 | Overall Survival with Osimertinib in Untreated, EGFR -Mutated Advanced NSCLC Suresh S. Ramalingam et al. · New England Journal of Medicine | 21 Nov 2019 | 2,933 |
| 9 | Fibroblast growth factor signalling: from development to cancer Nicholas C. Turner, Richard Philip Grose · Nature reviews. Cancer | 22 Jan 2010 | 2,724 |
| 10 | THE DEVELOPMENT OF FIBROBLAST COLONIES IN MONOLAYER CULTURES OF GUINEA‐PIG BONE MARROW AND SPLEEN CELLS A. J. Friedenstein, R. K. Chailakhjan, K. S. Lalykina · Cell Proliferation | Oct 1970 | 2,717 |
| 11 | TEAD mediates YAP-dependent gene induction and growth control Bin Zhao, Xin Ye, Jindan Yu et al. · Genes & Development | 25 Jun 2008 | 2,583 |
| 12 | Role of platelet-derived growth factors in physiology and medicine Johanna Andræ, Radiosa Gallini, Christer Betsholtz · Genes & Development | 15 May 2008 | 2,479 |
| 13 | Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor Avner Yayon, Michael Klagsbrun, Jeffrey D. Esko et al. · Cell | Feb 1991 | 2,448 |
| 14 | Stromal fibroblasts in cancer initiation and progression Neil A. Bhowmick, Eric G. Neilson, Harold L. Moses · Nature | Nov 2004 | 2,313 |
| 15 | Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma Paolo P. Provenzano, Carlos Mario Cuevas, Amy E. Chang et al. · Cancer Cell | Mar 2012 | 2,215 |
| 16 | Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone Anjali P. Kusumbe, Saravana Kumar Ramasamy, Ralf H. Adams · Nature | 12 Mar 2014 | 2,193 |
| 17 | Hyaluronan: from extracellular glue to pericellular cue Bryan P. Toole · Nature reviews. Cancer | Jul 2004 | 2,150 |
| 18 | Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals Kornélia Polyák, Mong-Hong Lee, Hediye Erdjument‐Bromage et al. · Cell | Jul 1994 | 2,147 |
| 19 | The Fibroblast Growth Factor signaling pathway David M. Ornitz, Nobuyuki Itoh · Wiley Interdisciplinary Reviews Developmental Biology | 13 Mar 2015 | 2,129 |
| 20 | FGF-21 as a novel metabolic regulator Alexei Kharitonenkov, Tatiyana L. Shiyanova, Anja Köester et al. · Journal of Clinical Investigation | 3 May 2005 | 2,126 |
| 21 | FGF23 induces left ventricular hypertrophy Christian Faul et al. · Journal of Clinical Investigation | 10 Oct 2011 | 2,030 |
| 22 | Turning foes to friends: targeting cancer-associated fibroblasts Xueman Chen, Erwei Song · Nature Reviews Drug Discovery | 23 Nov 2018 | 1,999 |
| 23 | Fibroblast growth factors. David M. Ornitz, Nobuyuki Itoh · Genome biology | 2001 | 1,974 |
| 24 | Regulation of Mammalian O 2 Homeostasis by Hypoxia-Inducible Factor 1 Gregg L. Semenza · Annual Review of Cell and Developmental Biology | Nov 1999 | 1,950 |
| 25 | Cellular signaling by fibroblast growth factor receptors Veraragavan P. Eswarakumar, Irit Lax, Joseph Schlessinger · Cytokine & Growth Factor Reviews | 2 Feb 2005 | 1,948 |
| 26 | The FGF family: biology, pathophysiology and therapy Andrew Beenken, Moosa Mohammadi · Nature Reviews Drug Discovery | 27 Feb 2009 | 1,946 |
| 27 | Receptor Specificity of the Fibroblast Growth Factor Family David M. Ornitz, Jian Xu, Jennifer S. Colvin et al. · Journal of Biological Chemistry | Jun 1996 | 1,907 |
| 28 | Hyaluronan 1 Torvard C. Laurent, J. R. E. Fraser · The FASEB Journal | Apr 1992 | 1,876 |
| 29 | Sotorasib for Lung Cancers with KRAS p.G12C Mutation Ferdinandos Skoulidis et al. · New England Journal of Medicine | 4 Jun 2021 | 1,862 |
| 30 | Klotho converts canonical FGF receptor into a specific receptor for FGF23 Itaru Urakawa, Yuji Yamazaki, Takashi Shimada et al. · Nature | 29 Oct 2006 | 1,855 |
| 31 | Gefitinib in Combination With Paclitaxel and Carboplatin in Advanced Non–Small-Cell Lung Cancer: A Phase III Trial—INTACT 2 Roy S. Herbst, Giuseppe Giaccone, Joan H. Schiller et al. · Journal of Clinical Oncology | 27 Feb 2004 | 1,723 |
| 32 | Bile acids: regulation of synthesis John Y.L. Chiang · Journal of Lipid Research | 3 Apr 2009 | 1,656 |
| 33 | The role of myeloid cells in the promotion of tumour angiogenesis Craig Murdoch, Munitta Muthana, Seth B. Coffelt et al. · Nature reviews. Cancer | 17 Jul 2008 | 1,646 |
| 34 | Heparan sulphate proteoglycans fine-tune mammalian physiology Joseph R. Bishop, Manuela Schuksz, Jeffrey D. Esko · Nature | Apr 2007 | 1,639 |
| 35 | Activity of SU11248, a Multitargeted Inhibitor of Vascular Endothelial Growth Factor Receptor and Platelet-Derived Growth Factor Receptor, in Patients With Metastatic Renal Cell Carcinoma Robert John Motzer, Marc Dror Michaelson, Bruce G. Redman et al. · Journal of Clinical Oncology | 5 Dec 2005 | 1,637 |
| 36 | Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study Ghassan K. Abou‐Alfa, Vaibhav Sahai, Antoine Hollebecque et al. · The Lancet Oncology | 20 Mar 2020 | 1,634 |
| 37 | Epidermal growth factor. G Carpenter, Steven B. Cohen · Journal of Biological Chemistry | Jun 1990 | 1,629 |
| 38 | Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23 Kenneth E. White, W. Evans, Jeffery L.H. O'Riordan et al. · Nature Genetics | Nov 2000 | 1,538 |
| 39 | Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21 Takeshi Inagaki, Paul A. Dutchak, Guixiang Zhao et al. · Cell Metabolism | Jun 2007 | 1,512 |
| 40 | Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation Alan C. Rapraeger, Alison Krufka, Bradley B. Olwin · Science | 21 Jun 1991 | 1,507 |
| 41 | Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States Michael K. Badman, Pavlos Pissios, Adam Richard Kennedy et al. · Cell Metabolism | Jun 2007 | 1,501 |
| 42 | Order Out of Chaos: Assembly of Ligand Binding Sites in Heparan Sulfate Jeffrey D. Esko, Scott B. Selleck · Annual Review of Biochemistry | Jun 2002 | 1,492 |
| 43 | FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis ffolliott Martin Fisher, Sandra Kleiner, Nicholas Douris et al. · Genes & Development | Feb 2012 | 1,484 |
| 44 | Induction of c-fos gene and protein by growth factors precedes activation of c-myc Rolf Müller, Rodrigo Bravo, Jean Burckhardt et al. · Nature | Dec 1984 | 1,419 |
| 45 | Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma Caroline Robert et al. · New England Journal of Medicine | 4 Jun 2019 | 1,412 |
| 46 | Scatter factor/hepatocyte growth factor is essential for liver development Claudia S. Schmidt, Friedhelm Bladt, Stefanie Goedecke et al. · Nature | Feb 1995 | 1,409 |
| 47 | Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation Cheng‐Jun Hu, Li-Yi Wang, Lewis A. Chodosh et al. · Molecular and Cellular Biology | 26 Nov 2003 | 1,407 |
| 48 | Erdafitinib in Locally Advanced or Metastatic Urothelial Carcinoma Yohann Loriot et al. · New England Journal of Medicine | 24 Jul 2019 | 1,396 |
| 49 | Regulation of Fibroblast Growth Factor-23 Signaling by Klotho Hiroshi Kurosu, Yasushi Ogawa, Masayoshi Miyoshi et al. · Journal of Biological Chemistry | 25 Jan 2006 | 1,373 |
| 50 | Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of T H 2 Inflammation Stephen John Jenkins, Dominik Rückerl, Peter C. Cook et al. · Science | 13 May 2011 | 1,362 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.