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Topic · Molecular Biology

Fibroblast Growth Factor Research

Fibroblast Growth Factor Research is a research topic within Molecular Biology. Science Explorer counts 17k research works in it since 1950. 10.2% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the Fibroblast Growth Factor (FGF) signaling pathway, covering its role in development, metabolism, cancer, and therapy. It explores the involvement of FGF21, FGF receptors, and PPARa in various physiological processes such as hepatic lipid metabolism, insulin sensitivity, and bone development. Additionally, it discusses the potential therapeutic implications of targeting FGF signaling in conditions like obesity and cancer.

  • Fibroblast Growth Factor
  • FGF21
  • Receptor
  • Signaling
  • Cancer
  • Metabolism
  • Therapy
  • Development
  • PPARa
  • Obesity
Research works
17k
fractional, since 1950
In the world top 10%
1.8k
per year above
Top-10% rate
10.2%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+0%
the tick is no change
Largest producer
China
40% of the 10 largest, 2022-now
Fibroblast Growth Factor Research

Which countries lead Fibroblast Growth Factor Research research?

By volume, China and the United States publish the most (930 and 671 works in 2022-now).

By volume, 2022-now

  1. 1 China 930 works
  2. 2 United States 671 works
  3. 3 Japan 187 works
  4. 4 Germany 108 works
  5. 5 India 86 works
  6. 6 Italy 85 works
  7. 7 South Korea 78 works
  8. 8 France 71 works
  9. 9 United Kingdom 70 works
  10. 10 Spain 59 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 39.6%United States: 28.6%Japan: 8.0%Germany: 4.6%6 others listed: 19.2%40%largest
China930 · 39.6%United States671 · 28.6%Japan187 · 8.0%Germany108 · 4.6%6 others listed449 · 19.2%

Shares of the rows listed above, not of the whole node.

Which institutions lead Fibroblast Growth Factor Research research?

By volume in 2022-now, Wenzhou Medical University publishes the most Fibroblast Growth Factor Research research, followed by Harvard University and Shanghai Jiao Tong University.

By volume, 2022-now

  1. 1 Wenzhou Medical UniversityChina 48 works
  2. 2 Harvard UniversityUnited States 33 works
  3. 3 Shanghai Jiao Tong UniversityChina 27 works
  4. 4 Sun Yat-sen UniversityChina 26 works
  5. 5 Sichuan UniversityChina 25 works
  6. 6 Nanjing Medical UniversityChina 20 works
  7. 7 Zhejiang UniversityChina 16 works
  8. 8 InsermFrance 16 works
  9. 9 Fudan UniversityChina 15 works
  10. 10 Central South UniversityChina 15 works

Who are the leading researchers in Fibroblast Growth Factor Research?

The most-cited researchers publishing on Fibroblast Growth Factor Research include Gad A. Getz, Elaine R. Mardis and Hermann Brenner.

  1. 1 Gad A. Getz United States 364k citations
  2. 2 Elaine R. Mardis United States 346k citations
  3. 3 Hermann Brenner Germany 343k citations
  4. 4 Shizuo Akira Japan 342k citations
  5. 5 Róbert Langer United States 303k citations
  6. 6 Robert A. Weinberg United States 301k citations
  7. 7 Luigi Ferrucci United States 281k citations
  8. 8 Matthew M. Meyerson United States 280k citations
  9. 9 Michael Karin United States 276k citations
  10. 10 Josef Coresh United States 272k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Fibroblast Growth Factor Research?

The most cited paper in Fibroblast Growth Factor Research is "A modified uronic acid carbazole reaction" (Thomas Bitter, H. M. Muir, 1962), with 6,285 citations. Next come "Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial" (5,578) and "The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis" (5,248).

Most cited papers
#PaperReleasedCitations
1 A modified uronic acid carbazole reaction Thomas Bitter, H. M. Muir · Analytical Biochemistry Oct 1962 6,285
2 Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial Masatoshi Kudo et al. · The Lancet Open access Mar 2018 5,578
3 The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis Patrick Henry Maxwell, Michael Sean Wiesener, Gin-Wen Chang et al. · Nature May 1999 5,248
4 HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing Mircea Ivan, Keiichi Kondo, Haifeng Yang et al. · Science Open access 20 Apr 2001 4,757
5 The biology and function of fibroblasts in cancer Raghu K. Kalluri · Nature reviews. Cancer Review 23 Aug 2016 4,462
All 100 most cited papers, with filters and sorting

Where is Fibroblast Growth Factor Research research done?

The largest centres of Fibroblast Growth Factor Research research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Wenzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Wenzhou.

Largest cities, 2022-now

  1. 1 BeijingChina 92 works
  2. 2 ShanghaiChina 84 works
  3. 3 GuangzhouChina 59 works
  4. 4 WenzhouChina 53 works
  5. 5 NanjingChina 45 works
  6. 6 TokyoJapan 43 works
  7. 7 HangzhouChina 42 works
  8. 8 SeoulSouth Korea 40 works
  9. 9 New YorkUnited States 37 works
  10. 10 ChengduChina 33 works

Where it is the local speciality

  1. WenzhouCN · 52.7 works21×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Fibroblast Growth Factor Research than the world average.

See Fibroblast Growth Factor Research on the map

Where is the best place to study Fibroblast Growth Factor Research?

Among universities, judged by research, Wenzhou Medical University, Harvard University and Sichuan University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 16.35%fractional works in this field (log) →share of work in the world top 10% →Sichuan UniversityHarvard UniversityWenzhou Medical Univ…Sun Yat-sen University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Wenzhou Medical UniversityChina 77.816.4%37.3×48 +27.0%
2Harvard UniversityUnited States 76.518.1%4.0×33 -10.3%
3Sichuan UniversityChina 71.724.5%4.3×25 +58.7%
4Sun Yat-sen UniversityChina 56.611.9%4.9×26 +22.4%
5Shanghai Jiao Tong UniversityChina 56.414.3%3.6×27 +7.5%
6Peking UniversityChina 55.818.7%2.8×15 +20.4%
7Yale UniversityUnited States 51.920.8%3.1×9 -7.3%
8Zhejiang UniversityChina 50.216.7%2.4×16 +23.3%
9Heidelberg UniversityGermany 45.17.9%6.2×12 +16.3%
10Fudan UniversityChina 44.114.2%3.8×15 -3.1%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Fibroblast Growth Factor Research, country by country

Is Fibroblast Growth Factor Research research growing?

Output in 2022-2025 was 0% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Fibroblast Growth Factor Research.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Fibroblast Growth Factor Research as a percentage of every work published that year, 0.011% in 2024.

still counting0.010%0.020%0.030%Fibroblast Growth Factor Research0.012% in 202519801990200020102020

Fractional works of Fibroblast Growth Factor Research over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Fibroblast Growth Factor Research10.2% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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