Topic · Fluorine in Organic Chemistry
Most cited papers in Fluorine in Organic Chemistry
What are the most cited papers in Fluorine in Organic Chemistry?
The most cited paper in Fluorine in Organic Chemistry is "Fluorine in medicinal chemistry" (Sophie Purser, Peter R. Moore, Steve Swallow et al., 2007), with 7,580 citations. Next come "Fluorine in Pharmaceuticals: Looking Beyond Intuition" (6,622) and "Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)" (4,838).
Showing 50 of 100 papers. Every paper with more than 600 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Fluorine in medicinal chemistry Sophie Purser, Peter R. Moore, Steve Swallow et al. · Chemical Society Reviews | 13 Dec 2007 | 7,580 |
| 2 | Fluorine in Pharmaceuticals: Looking Beyond Intuition Klaus Müller, Christoph Faeh, François Diederich · Science | 27 Sep 2007 | 6,622 |
| 3 | Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011) Jiang Wang, María Sánchez‐Roselló, José Luis Aceña et al. · Chemical Reviews | 3 Dec 2013 | 4,838 |
| 4 | Understanding organofluorine chemistry. An introduction to the C–F bond David O’Hagan · Chemical Society Reviews | 17 Oct 2007 | 4,043 |
| 5 | Applications of Fluorine in Medicinal Chemistry Eric P. Gillis, Kyle J. Eastman, Matthew Davenport Hill et al. · Journal of Medicinal Chemistry | 22 Jul 2015 | 3,653 |
| 6 | The Many Roles for Fluorine in Medicinal Chemistry William K. Hagmann · Journal of Medicinal Chemistry | 21 Jun 2008 | 3,617 |
| 7 | Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas Yu Chang Zhou, Jiang Wang, Zhanni Gu et al. · Chemical Reviews | 12 Jan 2016 | 2,807 |
| 8 | Dual Catalysis Strategies in Photochemical Synthesis Kazimer L. Skubi, Travis R. Blum, Tehshik P. Yoon · Chemical Reviews | 25 Apr 2016 | 2,724 |
| 9 | Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design Nicholas A. Meanwell · Journal of Medicinal Chemistry | 5 Feb 2018 | 2,663 |
| 10 | Introduction of Fluorine and Fluorine‐Containing Functional Groups Theresa Liang, Constanze N. Neumann, Tobias Ritter · Angewandte Chemie International Edition | 19 Jul 2013 | 2,578 |
| 11 | Catalysis for fluorination and trifluoromethylation Takeru Furuya, Adam S. Kamlet, Tobias Ritter · Nature | May 2011 | 2,227 |
| 12 | On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition‐Metal Complexes Eric M. Simmons, John F. Hartwig · Angewandte Chemie International Edition | 5 Mar 2012 | 2,160 |
| 13 | Direct C−H Transformation via Iron Catalysis Chang‐Liang Sun, Bi‐Jie Li, Zhang‐Jie Shi · Chemical Reviews | 4 Nov 2010 | 1,979 |
| 14 | Contribution of Organofluorine Compounds to Pharmaceuticals Munenori Inoue, Yuji Sumii, Norio Shibata · ACS Omega | 22 Apr 2020 | 1,948 |
| 15 | Aromatic Trifluoromethylation with Metal Complexes Olesya A. Tomashenko, Vladimir V. Grushin · Chemical Reviews | Apr 2011 | 1,763 |
| 16 | Data-Mining for Sulfur and Fluorine: An Evaluation of Pharmaceuticals To Reveal Opportunities for Drug Design and Discovery Elizabeth A. Ilardi, Edon Vitaku, Jón T. Njardarson · Journal of Medicinal Chemistry | 8 Oct 2013 | 1,617 |
| 17 | Fluorine in Medicinal Chemistry Hans‐Joachim Böhm, David W. Banner, Stefanie Bendels et al. · ChemBioChem | 28 Apr 2004 | 1,572 |
| 18 | Organic fluorine compounds: a great opportunity for enhanced materials properties Ricarda M. L. Berger, Giuseppe Resnati, Pierangelo Metrangolo et al. · Chemical Society Reviews | 2011 | 1,518 |
| 19 | Fluorine substituent effects (on bioactivity) Bruce E. Smart · Journal of Fluorine Chemistry | Jun 2001 | 1,488 |
| 20 | Facile Catalyst Separation Without Water: Fluorous Biphase Hydroformylation of Olefins István T. Horváth, József Rábai · Science | 7 Oct 1994 | 1,414 |
| 21 | Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry Jiajia Dong, Larissa B. Krasnova, M. G. Finn et al. · Angewandte Chemie International Edition | 11 Aug 2014 | 1,410 |
| 22 | Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions Xiaoyu Yang, Tao Wu, Robert J. Phipps et al. · Chemical Reviews | 22 Oct 2014 | 1,390 |
| 23 | Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis David A. Nagib, David W. C. MacMillan · Nature | Dec 2011 | 1,337 |
| 24 | Polyfluoroalkyl Chemicals in the U.S. Population: Data from the National Health and Nutrition Examination Survey (NHANES) 2003–2004 and Comparisons with NHANES 1999–2000 Antonia M. Calafat, Lee-Yang Wong, Zsuzsanna Kuklenyik et al. · Environmental Health Perspectives | 27 Aug 2007 | 1,253 |
| 25 | Good Partnership between Sulfur and Fluorine: Sulfur-Based Fluorination and Fluoroalkylation Reagents for Organic Synthesis Chuanfa Ni, Mingyou Hu, Jinbo Hu · Chemical Reviews | 21 Aug 2014 | 1,224 |
| 26 | AMBER : Assisted model building with energy refinement. A general program for modeling molecules and their interactions Paul K. Weiner, Peter A. Kollman · Journal of Computational Chemistry | Sep 1981 | 1,187 |
| 27 | Organosilicon Molecules with Medicinal Applications Annaliese K. Franz, Sean O. Wilson · Journal of Medicinal Chemistry | 12 Oct 2012 | 1,152 |
| 28 | Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments Kenneth L. Kirk · Organic Process Research & Development | 26 Jan 2008 | 1,151 |
| 29 | Modern Variants of the Mannich Reaction Michael Arend, Bernhard Westermann, Nikolaus Risch · Angewandte Chemie International Edition | 4 May 1998 | 1,140 |
| 30 | Recent Advances in the Synthesis of Cyclobutanes by Olefin [2 + 2] Photocycloaddition Reactions Saner Poplata, Andreas Tröster, You‐Quan Zou et al. · Chemical Reviews | 28 Mar 2016 | 1,134 |
| 31 | RESPIRATORY ENZYMES IN OXIDATIVE PHOSPHORYLATION Britton Chance, Gene R. Williams · Journal of Biological Chemistry | Nov 1955 | 1,128 |
| 32 | Fluorine in medicinal chemistry: A review of anti-cancer agents Chukwuemeka Isanbor, David O’Hagan · Journal of Fluorine Chemistry | 24 Feb 2006 | 1,121 |
| 33 | Carbon–Carbon Bond Forming Reactions via Photogenerated Intermediates Davide Ravelli, Stefano Protti, Maurizio Fagnoni · Chemical Reviews | 12 Apr 2016 | 1,119 |
| 34 | Trifluoromethyltrimethylsilane: Nucleophilic Trifluoromethylation and Beyond Xiao Liu, Cong Xu, Mang Wang et al. · Chemical Reviews | 22 Apr 2014 | 1,097 |
| 35 | Carbon Trifluoromethylation Reactions of Hydrocarbon Derivatives and Heteroarenes Concepción Alonso, Edorta Martínez de Marigorta, Gloria Rubiales et al. · Chemical Reviews | 30 Jan 2015 | 1,079 |
| 36 | A “Renaissance” in Radical Trifluoromethylation Armido Studer · Angewandte Chemie International Edition | 13 Aug 2012 | 1,076 |
| 37 | Synthetic Methods for Compounds Having CF 3 –S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions Xiu‐Hua Xu, Kohei Matsuzaki, Norio Shibata · Chemical Reviews | 14 Aug 2014 | 1,072 |
| 38 | Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates Jing Nie, Hongchao Guo, Dominique Cahard et al. · Chemical Reviews | 30 Nov 2010 | 1,070 |
| 39 | Perfluoroalkylation with Organosilicon Reagents G. K. Surya Prakash, Andrei K. Yudin · Chemical Reviews | May 1997 | 1,022 |
| 40 | Ionic liquids are not always green: hydrolysis of 1-butyl-3-methylimidazolium hexafluorophosphate Richard P. Swatloski, John D. Holbrey, Robin Don Rogers · Green Chemistry | 2003 | 983 |
| 41 | Enantioselective α-Trifluoromethylation of Aldehydes via Photoredox Organocatalysis David A. Nagib, Mark E. Scott, David W. C. MacMillan · Journal of the American Chemical Society | 20 Jul 2009 | 981 |
| 42 | Visible Light-Mediated Atom Transfer Radical Addition via Oxidative and Reductive Quenching of Photocatalysts Carl‐Johan Wallentin, John D. M. Nguyen, Peter Finkbeiner et al. · Journal of the American Chemical Society | 9 Apr 2012 | 979 |
| 43 | Fluorine in crystal engineering—“the little atom that could” Katharina Reichenbächer, Heike I. Süss, J. Hulliger · Chemical Society Reviews | Dec 2004 | 969 |
| 44 | Monofluorination of Organic Compounds: 10 Years of Innovation Pier Alexandre Champagne, Justine Desroches, Jean‐Denys Hamel et al. · Chemical Reviews | 9 Apr 2015 | 968 |
| 45 | FLUORIDE-INDUCED 1,2-ELIMINATION OF O -TRIMETHYLSILYLPHENYL TRIFLATE TO BENZYNE UNDER MILD CONDITIONS Yoshio Himeshima, Takaaki Sonoda, Hiroshi Kobayashi · Chemistry Letters | Aug 1983 | 942 |
| 46 | Organic Fluorine Hardly Ever Accepts Hydrogen Bonds Jack David Dunitz, Robin Taylor · Chemistry - A European Journal | 1997 | 936 |
| 47 | A Method for the Quantitative Modification and Estimation of Carboxylic Acid Groups in Proteins D. G. Hoare, Daniel E. Koshland · Journal of Biological Chemistry | May 1967 | 934 |
| 48 | Practical and innate carbon–hydrogen functionalization of heterocycles Yuta Fujiwara, Janice A. Dixon, Fionn O’Hara et al. · Nature | 27 Nov 2012 | 933 |
| 49 | Addition of CF 3 across unsaturated moieties: a powerful functionalization tool Estı́baliz Merino, Cristina Nevado · Chemical Society Reviews | 2014 | 926 |
| 50 | Successful fluorine-containing herbicide agrochemicals Tomoya Fujiwara, David O’Hagan · Journal of Fluorine Chemistry | 21 Jun 2014 | 900 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.