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Most cited papers in Genetic and Kidney Cyst Diseases

What are the most cited papers in Genetic and Kidney Cyst Diseases?

The most cited paper in Genetic and Kidney Cyst Diseases is "Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness" (Michiru Nishita, Seung‐Yeol Park, Tadashi Nishio et al., 2017), with 16,101 citations. Next come "Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver" (2,862) and "Primary carcinoma of the liver.A study of 100 cases among 48,900 necropsies" (2,816).

Showing 50 of 100 papers. Every paper with more than 725 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness Michiru Nishita, Seung‐Yeol Park, Tadashi Nishio et al. · Scientific Reports Open access 24 Jan 2017 16,101
2 Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver Scott L. Friedman · Physiological Reviews ReviewOpen access 2008 2,862
3 Primary carcinoma of the liver.A study of 100 cases among 48,900 necropsies Hugh A. Edmondson, Paul E. Steiner · Cancer May 1954 2,816
4 Mechanisms of Hepatic Fibrogenesis Scott L. Friedman · Gastroenterology Open access May 2008 2,649
5 Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Bernard J. Escudier, Camillo Porta, Manuela Schmidinger et al. · Annals of Oncology Open access Sep 2014 2,263
6 Identification and proteomic profiling of exosomes in human urine Trairak Pisitkun, Rong‐Fong Shen, Mark A. Knepper · Proceedings of the National Academy of Sciences Open access 23 Aug 2004 2,196
7 Aggresomes: A Cellular Response to Misfolded Proteins Jennifer A. Johnston, Cristina L. Ward, Ron R. Kopito · The Journal of Cell Biology Open access 28 Dec 1998 2,172
8 Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells Surya M. Nauli, Francis J. Alenghat, Ying Luo et al. · Nature Genetics 6 Jan 2003 2,064
9 Kinesin superfamily motor proteins and intracellular transport Nobutaka Hirokawa, Yasuko Noda, Yosuke Tanaka et al. · Nature Reviews Molecular Cell Biology Review 23 Sep 2009 1,942
10 The primary cilium: a signalling centre during vertebrate development Sarah C. Goetz, Kathryn V. Anderson · Nature Reviews Genetics ReviewOpen access 16 Apr 2010 1,905
11 Mutations of the VHL tumour suppressor gene in renal carcinoma James R. Gnarra et al. · Nature Genetics May 1994 1,752
12 Genes and molecular pathways underpinning ciliopathies Jeremy F. Reiter, Michel R. Leroux · Nature Reviews Molecular Cell Biology ReviewOpen access 12 Jul 2017 1,751
13 The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications Ahmad Abdelzaher Zaki Khalifa, Muneyoshi Ichikawa, Daniel Dai et al. · eLife Open access 17 Jan 2020 1,713
14 Randomization of Left–Right Asymmetry due to Loss of Nodal Cilia Generating Leftward Flow of Extraembryonic Fluid in Mice Lacking KIF3B Motor Protein Shigenori Nonaka, Yosuke Tanaka, Yasushi Okada et al. · Cell Open access Dec 1998 1,630
15 Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease Vicente E. Torres, Arlene B. Chapman, Olivier Devuyst et al. · New England Journal of Medicine Open access 3 Nov 2012 1,628
16 Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret Anita Schuchardt, Vivette Denise D’Agati, Lena Larsson-Blomberg et al. · Nature 1994 1,628
17 Autosomal dominant polycystic kidney disease Vicente E. Torres, Peter Christian Harris, Yves Pirson · The Lancet Apr 2007 1,564
18 Vertebrate Smoothened functions at the primary cilium Kevin C. Corbit, Pia Aanstad, Veena Singla et al. · Nature 31 Aug 2005 1,522
19 Cell Biology of the Glomerular Podocyte Hermann Pavenstädt, Wilhelm Kriz, Matthias Kretzler · Physiological Reviews Review 2003 1,510
20 Patched1 Regulates Hedgehog Signaling at the Primary Cilium Rajat Rohatgi, Ljiljana Milenković, Matthew P. Scott · Science 19 Jul 2007 1,483
21 Hedgehog signalling in the mouse requires intraflagellar transport proteins Danwei Huangfu, Aimin Liu, Andrew S. Rakeman et al. · Nature Nov 2003 1,462
22 Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology Ingmar Mederacke, Christine Cho-Shing Hsu, Juliane S. Troeger et al. · Nature Communications Open access 22 Nov 2013 1,447
23 Intraflagellar transport Joel L. Rosenbaum, George B. Witman · Nature Reviews Molecular Cell Biology Review Nov 2002 1,432
24 PKD2 , a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein Toshio Mochizuki, Guanqing Wu, Tomohito Hayashi et al. · Science 31 May 1996 1,425
25 A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis Maxence V. Nachury, Alexander V. Loktev, Qihong Zhang et al. · Cell Open access Jun 2007 1,414
26 Ciliopathies Friedhelm Hildebrandt, Thomas R. Benzing, Nicholas Katsanis · New England Journal of Medicine Open access 20 Apr 2011 1,383
27 The Heidelberg classification of renal cell tumours Gyula Kovács, Mohammed Akhtar, Bruce J. Beckwith et al. · The Journal of Pathology Open access Oct 1997 1,322
28 Degradation of CFTR by the ubiquitin-proteasome pathway Cristina L. Ward, Satoshi ŌMURA, Ron R. Kopito · Cell Open access Oct 1995 1,320
29 Specific Aquaporins Facilitate the Diffusion of Hydrogen Peroxide across Membranes Gerd Patrick Bienert, Anders L.B. Møller, Kim A. Kristiansen et al. · Journal of Biological Chemistry Open access 14 Nov 2006 1,315
30 When cilia go bad: cilia defects and ciliopathies Manfred Fliegauf, Thomas R. Benzing, Heymut Omran · Nature Reviews Molecular Cell Biology Review 23 Oct 2007 1,313
31 Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping Manfred Gessler, Annemarie Poustka, Webster K. Cavenee et al. · Nature Open access Feb 1990 1,307
32 Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1 Linheng Li, Ian D. Krantz, Yu Deng et al. · Nature Genetics Jul 1997 1,306
33 Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets Sandrine Boyault, David S. Rickman, Aurélien de Reyniès et al. · Hepatology Open access 22 Dec 2006 1,288
34 Small Hepatocellular Carcinoma: Treatment with Radio-frequency Ablation versus Ethanol Injection Tito Livraghi, Shraga Nahum Goldberg, Sergio Lazzaroni et al. · Radiology Mar 1999 1,282
35 A Human Syndrome Caused by Immotile Cilia Björn A. Afzelius · Science 23 Jul 1976 1,268
36 Renal Mass and Localized Renal Cancer: AUA Guideline Steven C. Campbell, Robert G. Uzzo, Mohamad Ezzeddine Allaf et al. · The Journal of Urology Open access 4 May 2017 1,257
37 Complications following percutaneous liver biopsy Felice Piccinino et al. · Journal of Hepatology 1986 1,213
38 The Primary Cilium as the Cell's Antenna: Signaling at a Sensory Organelle Veena Singla, Jeremy F. Reiter · Science 3 Aug 2006 1,209
39 Mutations in the human Jagged1 gene are responsible for Alagille syndrome Takaya Oda, ABDEL G. ELKAHLOUN, Brian L. Pike et al. · Nature Genetics Jul 1997 1,177
40 The Ciliopathies: An Emerging Class of Human Genetic Disorders José Luis Badano, Norimasa Mitsuma, Phil L. Beales et al. · Annual Review of Genomics and Human Genetics Review 7 Jul 2006 1,170
41 Overview of Structure and Function of Mammalian Cilia Peter Satir, Søren T. Christensen · Annual Review of Physiology Review 29 Sep 2006 1,161
42 Chlamydomonas IFT 88 and Its Mouse Homologue, Polycystic Kidney Disease Gene Tg 737, Are Required for Assembly of Cilia and Flagella Gregory J. Pazour, Bethany L. Dickert, Yvonne Vucica et al. · The Journal of Cell Biology Open access 30 Oct 2000 1,155
43 A Conditionally Immortalized Human Podocyte Cell Line Demonstrating Nephrin and Podocin Expression Moin Ahson Saleem, Michael J. O’Hare, Jochen Reiser et al. · Journal of the American Society of Nephrology Mar 2002 1,147
44 Liver Failure and Death after Exposure to Microcystins at a Hemodialysis Center in Brazil Elise M. Jochimsen, Wayne W. Carmichael, Jisi An et al. · New England Journal of Medicine Open access 26 Mar 1998 1,111
45 Transplantation of living nuclei from blastula cells into enucleated frogs’ eggs Robert Briggs, Thomas J. King · Proceedings of the National Academy of Sciences Open access May 1952 1,110
46 Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4 Kevin L. Stark, Seppo Juhani Vainio, Galya Vassileva et al. · Nature Dec 1994 1,082
47 Proteomic analysis of a eukaryotic cilium Gregory J. Pazour, Nathan S. Agrin, John Leszyk et al. · The Journal of Cell Biology Open access 4 Jul 2005 1,067
48 The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia John R. Srigley, Brett Delahunt, John N. Eble et al. · The American Journal of Surgical Pathology 11 Sep 2013 1,055
49 Ciliogenesis: building the cell's antenna Hiroaki Ishikawa, Wallace F. Marshall · Nature Reviews Molecular Cell Biology Review 23 Mar 2011 1,008
50 Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development Akio Kobayashi, M. Todd Valerius, Joshua W. Mugford et al. · Cell stem cell Open access Aug 2008 1,005

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.