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Topic · Genetics

Genetic and Kidney Cyst Diseases

Genetic and Kidney Cyst Diseases is a research topic within Genetics. Science Explorer counts 21k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on ciliopathies, a group of genetic disorders involving defects in primary cilia structure and function. It covers a range of topics including polycystic kidney disease, intraflagellar transport, hedgehog signaling, Bardet–Biedl syndrome, nephronophthisis, and the role of ciliary proteins. The research aims to understand the genetic mechanisms and signaling pathways underlying these disorders.

  • Primary Cilium
  • Ciliopathies
  • Polycystic Kidney Disease
  • Intraflagellar Transport
  • Hedgehog Signaling
  • Bardet–Biedl Syndrome
  • Nephronophthisis
  • Ciliary Membrane
  • Autosomal Dominant Polycystic Kidney Disease
  • Ciliary Proteins
Research works
21k
fractional, since 1950
In the world top 10%
2.1k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+10%
the tick is no change
Largest producer
United States
34% of the 10 largest, 2022-now
Genetic and Kidney Cyst Diseases

Which countries lead Genetic and Kidney Cyst Diseases research?

By volume, the United States and China publish the most (1.1k and 716 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.1k works
  2. 2 China 716 works
  3. 3 Japan 288 works
  4. 4 India 203 works
  5. 5 Germany 174 works
  6. 6 Italy 155 works
  7. 7 United Kingdom 153 works
  8. 8 France 133 works
  9. 9 South Korea 102 works
  10. 10 Spain 98 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 34.3%China: 23.3%Japan: 9.4%India: 6.6%6 others listed: 26.5%34%largest
United States1,056 · 34.3%China716 · 23.3%Japan288 · 9.4%India203 · 6.6%6 others listed815 · 26.5%

Shares of the rows listed above, not of the whole node.

Which institutions lead Genetic and Kidney Cyst Diseases research?

By volume in 2022-now, Mayo Clinic publishes the most Genetic and Kidney Cyst Diseases research, followed by Harvard University and Inserm.

By volume, 2022-now

  1. 1 Mayo ClinicUnited States 54 works
  2. 2 Harvard UniversityUnited States 38 works
  3. 3 InsermFrance 26 works
  4. 4 Yale UniversityUnited States 26 works
  5. 5 Shanghai Jiao Tong UniversityChina 24 works
  6. 6 Sichuan UniversityChina 22 works
  7. 7 National Institutes of HealthUnited States 22 works
  8. 8 Nanjing Medical UniversityChina 22 works
  9. 9 Centre National de la Recherche ScientifiqueFrance 21 works
  10. 10 Zhejiang UniversityChina 20 works

Who are the leading researchers in Genetic and Kidney Cyst Diseases?

The most-cited researchers publishing on Genetic and Kidney Cyst Diseases include Eric S. Lander, Richard M. Durbin and Mark J. Daly.

  1. 1 Eric S. Lander United States 524k citations
  2. 2 Richard M. Durbin United Kingdom 410k citations
  3. 3 Mark J. Daly United States 403k citations
  4. 4 Stacey L. Gabriel United States 402k citations
  5. 5 Guido Kroemer France 386k citations
  6. 6 Jun Wang China 340k citations
  7. 7 Giuseppe Remuzzi Italy 328k citations
  8. 8 Robert A. Weinberg United States 301k citations
  9. 9 Richard A. Gibbs United States 292k citations
  10. 10 Todd R. Golub United States 283k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Genetic and Kidney Cyst Diseases?

The most cited paper in Genetic and Kidney Cyst Diseases is "Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness" (Michiru Nishita, Seung‐Yeol Park, Tadashi Nishio et al., 2017), with 16,101 citations. Next come "Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver" (2,862) and "Primary carcinoma of the liver.A study of 100 cases among 48,900 necropsies" (2,816).

Most cited papers
#PaperReleasedCitations
1 Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness Michiru Nishita, Seung‐Yeol Park, Tadashi Nishio et al. · Scientific Reports Open access 24 Jan 2017 16,101
2 Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver Scott L. Friedman · Physiological Reviews ReviewOpen access 2008 2,862
3 Primary carcinoma of the liver.A study of 100 cases among 48,900 necropsies Hugh A. Edmondson, Paul E. Steiner · Cancer May 1954 2,816
4 Mechanisms of Hepatic Fibrogenesis Scott L. Friedman · Gastroenterology Open access May 2008 2,649
5 Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Bernard J. Escudier, Camillo Porta, Manuela Schmidinger et al. · Annals of Oncology Open access Sep 2014 2,263
All 100 most cited papers, with filters and sorting

Where is Genetic and Kidney Cyst Diseases research done?

The largest centres of Genetic and Kidney Cyst Diseases research in 2022-now are Beijing (China), Tokyo (Japan), Paris (France) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in Rochester.

Largest cities, 2022-now

  1. 1 BeijingChina 87 works
  2. 2 TokyoJapan 80 works
  3. 3 ParisFrance 69 works
  4. 4 ShanghaiChina 66 works
  5. 5 SeoulSouth Korea 53 works
  6. 6 GuangzhouChina 52 works
  7. 7 LondonUnited Kingdom 45 works
  8. 8 New YorkUnited States 40 works
  9. 9 NanjingChina 35 works
  10. 10 BostonUnited States 34 works

Where it is the local speciality

  1. RochesterUS · 28.1 works18×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Genetic and Kidney Cyst Diseases than the world average.

See Genetic and Kidney Cyst Diseases on the map

Where is the best place to study Genetic and Kidney Cyst Diseases?

Among universities, judged by research, Harvard University, Yale University and University of Colorado Anschutz Medical Campus score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 17.53%fractional works in this field (log) →share of work in the world top 10% →Heidelberg UniversityHarvard UniversityUniversity of Colora…Yale University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 83.120.8%3.4×38 +5.9%
2Yale UniversityUnited States 70.113.1%6.7×26 +13.1%
3University of Colorado Anschutz Medical CampusUnited States 63.214.7%17.5×16 +54.9%
4Heidelberg UniversityGermany 62.221.2%4.4×12 +34.6%
5Johns Hopkins UniversityUnited States 59.819.7%2.7×15 +5.8%
6Wuhan UniversityChina 57.524.4%2.3×12 +100.4%
7Sichuan UniversityChina 57.219.5%2.8×22 +83.4%
8Nanjing Medical UniversityChina 57.214.1%6.8×22 +81.0%
9University of KansasUnited States 57.16.0%11.4×20 +24.5%
10University of California, San FranciscoUnited States 56.421.8%4.5×11 -28.2%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Genetic and Kidney Cyst Diseases, country by country

Is Genetic and Kidney Cyst Diseases research growing?

Output in 2022-2025 was 10% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Genetic and Kidney Cyst Diseases.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Genetic and Kidney Cyst Diseases as a percentage of every work published that year, 0.016% in 2024.

still counting0.010%0.020%0.030%Genetic and Kidney Cyst Diseases0.017% in 202519801990200020102020

Fractional works of Genetic and Kidney Cyst Diseases over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Genetic and Kidney Cyst Diseases9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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