Most cited papers in Glutathione Transferases and Polymorphisms
What are the most cited papers in Glutathione Transferases and Polymorphisms?
The most cited paper in Glutathione Transferases and Polymorphisms is "Glutathione S-Transferases" (William H. Habig, Michael J Pabst, William B. Jakoby, 1974), with 18,239 citations. Next come "Free radicals and antioxidants in normal physiological functions and human disease" (14,300) and "Free radicals, metals and antioxidants in oxidative stress-induced cancer" (6,682).
Showing 50 of 99 papers. Every paper with more than 1,225 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Glutathione S-Transferases William H. Habig, Michael J Pabst, William B. Jakoby · Journal of Biological Chemistry | Nov 1974 | 18,239 |
| 2 | Free radicals and antioxidants in normal physiological functions and human disease Marián Valko, Dieter Leibfritz, Ján Moncóľ et al. · The International Journal of Biochemistry & Cell Biology | 7 Aug 2006 | 14,300 |
| 3 | Free radicals, metals and antioxidants in oxidative stress-induced cancer Marián Valko, Christopher J. Rhodes, Ján Moncóľ et al. · Chemico-Biological Interactions | 24 Jan 2006 | 6,682 |
| 4 | Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Dunyaporn Trachootham, Jérôme Alexandre, Peng Huang · Nature Reviews Drug Discovery | 29 May 2009 | 5,449 |
| 5 | Oxidative stress, inflammation, and cancer: How are they linked? Simone Reuter, Subash C. Gupta, Madan Mohan Chaturvedi et al. · Free Radical Biology and Medicine | 17 Sep 2010 | 5,431 |
| 6 | Reactive oxygen species (ROS) as pleiotropic physiological signalling agents Helmut Sies, Dean P. Jones · Nature Reviews Molecular Cell Biology | 30 Mar 2020 | 5,273 |
| 7 | Oxidative Stress and Antioxidant Defense Esra Birben, Ümit Murat Şahiner, Cansın Saçkesen et al. · World Allergy Organization Journal | 2012 | 4,985 |
| 8 | Role of Nrf2 in Oxidative Stress and Toxicity Qiang Ma · The Annual Review of Pharmacology and Toxicology | 6 Jan 2013 | 4,940 |
| 9 | Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine Owen W. Griffith · Analytical Biochemistry | Jul 1980 | 4,625 |
| 10 | Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple Freya Q. Schafer, Garry R. Buettner · Free Radical Biology and Medicine | Jun 2001 | 4,588 |
| 11 | A simple method for clinical assay of superoxide dismutase. Yi Sun, Larry W. Oberley, Yi Li · Clinical Chemistry | Mar 1988 | 4,529 |
| 12 | Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling Paul D. Ray, Bowen Huang, Yoshiaki Tsuji · Cellular Signalling | 20 Jan 2012 | 4,423 |
| 13 | Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver M MORON, Joseph William DePierre, Bengt Mannervik · Biochimica et Biophysica Acta (BBA) - General Subjects | 4 Jan 1979 | 4,221 |
| 14 | Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland Paul Lichtenstein, Niels Vilstrup Holm, Pia K. Verkasalo et al. · New England Journal of Medicine | 13 Jul 2000 | 4,168 |
| 15 | An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements Ken Itoh, Tomoki Chiba, Satoru Takahashi et al. · Biochemical and Biophysical Research Communications | Jul 1997 | 4,013 |
| 16 | Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway Thomas W. Kensler, Nobunao Wakabayashi, Shyam S. Biswal · The Annual Review of Pharmacology and Toxicology | 29 Aug 2006 | 3,654 |
| 17 | Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh et al. · Genes & Development | 1999 | 3,637 |
| 18 | GLUTATHIONE TRANSFERASES John David Hayes, Jack U. Flanagan, Ian R. Jowsey · The Annual Review of Pharmacology and Toxicology | 2 Nov 2004 | 3,565 |
| 19 | The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I John David Hayes, David J. Pulford · Critical Reviews in Biochemistry and Molecular Biology | 1995 | 3,487 |
| 20 | The Biology of Oxygen Radicals Irwin Fridovich · Science | 8 Sep 1978 | 3,349 |
| 21 | Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT Bernard M. BABIOR, Ruby S. Kipnes, John T. Curnutte · Journal of Clinical Investigation | Mar 1973 | 2,944 |
| 22 | Assaying for superoxide dismutase activity: Some large consequences of minor changes in conditions Wayne F. Beyer, Irwin Fridovich · Analytical Biochemistry | Mar 1987 | 2,937 |
| 23 | Environmentally induced oxidative stress in aquatic animals Volodymyr I. Lushchak · Aquatic Toxicology | 26 Oct 2010 | 2,711 |
| 24 | The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress Truyen Nguyen, Paul Nioi, Cecil B. Pickett · Journal of Biological Chemistry | Feb 2009 | 2,697 |
| 25 | Oxidative Stress in Cancer John David Hayes, Albena T. Dinkova‐Kostova, Kenneth D. Tew · Cancer Cell | 9 Jul 2020 | 2,652 |
| 26 | Glutathione: Overview of its protective roles, measurement, and biosynthesis Henry Jay Forman, Hongqiao Zhang, Alessandra Rinna · Molecular Aspects of Medicine | 31 Aug 2008 | 2,644 |
| 27 | Physiological functions of thioredoxin and thioredoxin reductase Elias S.J. Arnér, Arne Holmgren · European Journal of Biochemistry | Oct 2000 | 2,553 |
| 28 | Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging Klaudia Jomová, Renáta Raptová, Suliman Yousef Alomar et al. · Archives of Toxicology | 19 Aug 2023 | 2,548 |
| 29 | Lung Cancer: Epidemiology, Etiology, and Prevention Charles S. Dela Cruz, Lynn T. Tanoue, Richard A. Matthay · Clinics in Chest Medicine | 4 Nov 2011 | 2,529 |
| 30 | Prooxidant States and Tumor Promotion P Cerutti · Science | 25 Jan 1985 | 2,515 |
| 31 | Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1 Masao Saitoh, Hideki Nishitoh, Makiko Fujii et al. · The EMBO Journal | May 1998 | 2,396 |
| 32 | Cellular response to oxidative stress: Signaling for suicide and survival* Jennifer L. Martindale, Nikki J. Holbrook · Journal of Cellular Physiology | 24 May 2002 | 2,327 |
| 33 | Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis Gina M. DeNicola, Florian A. Karreth, Timothy J. Humpton et al. · Nature | Jul 2011 | 2,302 |
| 34 | Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2 Akira Kobayashi, Moon-Il Kang, Hiromi Okawa et al. · Molecular and Cellular Biology | 28 Jul 2004 | 2,239 |
| 35 | Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling Ying Wang, Robyn S. Branicky, Alycia Noë et al. · The Journal of Cell Biology | 18 Apr 2018 | 2,219 |
| 36 | The Nrf2 regulatory network provides an interface between redox and intermediary metabolism John David Hayes, Albena T. Dinkova‐Kostova · Trends in Biochemical Sciences | 20 Mar 2014 | 2,167 |
| 37 | Antioxidants Maintain Cellular Redox Homeostasis by Elimination of Reactive Oxygen Species Long He, Ting He, Shabnam Farrar et al. · Cellular Physiology and Biochemistry | 2017 | 2,147 |
| 38 | Nrf2-Keap1 signaling in oxidative and reductive stress Ilaria Bellezza, Ileana Giambanco, Alba Minelli et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 27 Feb 2018 | 2,083 |
| 39 | Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts Barry B. Halliwell, John M.C. Gutteridge · Archives of Biochemistry and Biophysics | May 1986 | 2,052 |
| 40 | Purification and characterization of the flavoenzyme glutathione reductase from rat liver. Inger Carlberg, Bengt Mannervik · Journal of Biological Chemistry | Jul 1975 | 2,027 |
| 41 | Glutathione metabolism and its selective modification. A Meister · Journal of Biological Chemistry | Nov 1988 | 2,026 |
| 42 | The importance of glutathione in human disease Danyelle M. Townsend, Kenneth D. Tew, Haïm Tapiero · Biomedicine & Pharmacotherapy | May 2003 | 2,015 |
| 43 | Regulation of antioxidant enzymes: a significant role for melatonin Carmen Rodrı́guez, Juan Carlos Mayo, Rosa María Sainz et al. · Journal of Pineal Research | 11 Dec 2003 | 2,004 |
| 44 | Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases Tohru Fukai, Masuko Ushio‐Fukai · Antioxidants and Redox Signaling | 7 Apr 2011 | 2,002 |
| 45 | Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants Albena T. Dinkova‐Kostova, Walter David Holtzclaw, Robert Norman Cole et al. · Proceedings of the National Academy of Sciences | 22 Aug 2002 | 1,953 |
| 46 | Multifactor-Dimensionality Reduction Reveals High-Order Interactions among Estrogen-Metabolism Genes in Sporadic Breast Cancer Marylyn DeRiggi Ritchie, Lance W. Hahn, Nady Roodi et al. · The American Journal of Human Genetics | Jul 2001 | 1,946 |
| 47 | Oxyradicals and DNA damage Lawrence J. Marnett · Carcinogenesis | Mar 2000 | 1,895 |
| 48 | Estrogen Carcinogenesis in Breast Cancer James D. Yager, Nancy E. Davidson · New England Journal of Medicine | 18 Jan 2006 | 1,882 |
| 49 | Role of oxygen radicals in DNA damage and cancer incidence Marián Valko, Mário Izakovič, Milan Mazúr et al. · Molecular and Cellular Biochemistry | Nov 2004 | 1,814 |
| 50 | Nrf2 signaling pathway: Pivotal roles in inflammation Syed Minhaj Uddin Ahmed, Lin Luo, Akhileshwar Namani et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 4 Nov 2016 | 1,807 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.