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Glutathione Transferases and Polymorphisms

Glutathione Transferases and Polymorphisms is a research topic within Molecular Biology. Science Explorer counts 17k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the role of glutathione transferases, superoxide dismutase, and genetic polymorphisms in oxidative stress response, cancer resistance, drug metabolism, and cell signaling. It investigates the impact of antioxidant enzymes on disease susceptibility and drug resistance, as well as their structural and functional characteristics. The research also delves into the implications of oxidative stress in various diseases and the potential for targeting glutathione-related pathways in therapeutic interventions.

  • Glutathione Transferases
  • Superoxide Dismutase
  • Oxidative Stress
  • Genetic Polymorphisms
  • Cancer Resistance
  • Antioxidant Enzymes
  • Drug Metabolism
  • Cell Signaling
  • Toxicology
  • Enzyme Structure
Research works
17k
fractional, since 1950
In the world top 10%
1.7k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-11%
the tick is no change
Largest producer
China
41% of the 10 largest, 2022-now
Glutathione Transferases and Polymorphisms

Which countries lead Glutathione Transferases and Polymorphisms research?

By volume, China and the United States publish the most (494 and 249 works in 2022-now).

By volume, 2022-now

  1. 1 China 494 works
  2. 2 United States 249 works
  3. 3 India 106 works
  4. 4 Russia 75 works
  5. 5 Türkiye 63 works
  6. 6 Japan 58 works
  7. 7 South Korea 47 works
  8. 8 Iran 46 works
  9. 9 Italy 38 works
  10. 10 Brazil 36 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 40.8%United States: 20.6%India: 8.8%Russia: 6.2%6 others listed: 23.7%41%largest
China494 · 40.8%United States249 · 20.6%India106 · 8.8%Russia75 · 6.2%6 others listed287 · 23.7%

Shares of the rows listed above, not of the whole node.

Which institutions lead Glutathione Transferases and Polymorphisms research?

By volume in 2022-now, Russian Academy of Sciences publishes the most Glutathione Transferases and Polymorphisms research, followed by Nanjing Medical University and Zhejiang University.

Who are the leading researchers in Glutathione Transferases and Polymorphisms?

The most-cited researchers publishing on Glutathione Transferases and Polymorphisms include George Davey Smith, Walter Churchill Willett and Julian P. T. Higgins.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Walter Churchill Willett United States 411k citations
  3. 3 Julian P. T. Higgins United Kingdom 390k citations
  4. 4 Hermann Brenner Germany 343k citations
  5. 5 Jun Wang China 340k citations
  6. 6 Giuseppe Remuzzi Italy 328k citations
  7. 7 Reza Malekzadeh Iran 278k citations
  8. 8 Hagop M. Kantarjian United States 273k citations
  9. 9 Josef Coresh United States 272k citations
  10. 10 Gordon Brent Mills United States 265k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Glutathione Transferases and Polymorphisms?

The most cited paper in Glutathione Transferases and Polymorphisms is "Glutathione S-Transferases" (William H. Habig, Michael J Pabst, William B. Jakoby, 1974), with 18,239 citations. Next come "Free radicals and antioxidants in normal physiological functions and human disease" (14,300) and "Free radicals, metals and antioxidants in oxidative stress-induced cancer" (6,682).

Most cited papers
#PaperReleasedCitations
1 Glutathione S-Transferases William H. Habig, Michael J Pabst, William B. Jakoby · Journal of Biological Chemistry Open access Nov 1974 18,239
2 Free radicals and antioxidants in normal physiological functions and human disease Marián Valko, Dieter Leibfritz, Ján Moncóľ et al. · The International Journal of Biochemistry & Cell Biology 7 Aug 2006 14,300
3 Free radicals, metals and antioxidants in oxidative stress-induced cancer Marián Valko, Christopher J. Rhodes, Ján Moncóľ et al. · Chemico-Biological Interactions 24 Jan 2006 6,682
4 Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Dunyaporn Trachootham, Jérôme Alexandre, Peng Huang · Nature Reviews Drug Discovery Review 29 May 2009 5,449
5 Oxidative stress, inflammation, and cancer: How are they linked? Simone Reuter, Subash C. Gupta, Madan Mohan Chaturvedi et al. · Free Radical Biology and Medicine Open access 17 Sep 2010 5,431
All 99 most cited papers, with filters and sorting

Where is Glutathione Transferases and Polymorphisms research done?

The largest centres of Glutathione Transferases and Polymorphisms research in 2022-now are Beijing (China), Guangzhou (China), Shanghai (China) and Nanjing (China).

Largest cities, 2022-now

  1. 1 BeijingChina 51 works
  2. 2 GuangzhouChina 27 works
  3. 3 ShanghaiChina 25 works
  4. 4 NanjingChina 24 works
  5. 5 MoscowRussia 23 works
  6. 6 SeoulSouth Korea 19 works
  7. 7 HangzhouChina 18 works
  8. 8 ChongqingChina 17 works
  9. 9 WuhanChina 15 works
  10. 10 TehranIran 15 works
See Glutathione Transferases and Polymorphisms on the map

Where is the best place to study Glutathione Transferases and Polymorphisms?

Among universities, judged by research, Zhejiang University, Nanjing Medical University and Sun Yat-sen University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Zhejiang UniversityChina 55.233.8%2.1×8 +0.9%
2Nanjing Medical UniversityChina 46.014.2%7.3×10 +4.2%
3Sun Yat-sen UniversityChina 34.921.3%2.8×8 -4.1%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Glutathione Transferases and Polymorphisms, country by country

Is Glutathione Transferases and Polymorphisms research growing?

Output in 2022-2025 was 11% lower than in 2018-2021, peaking in 2012.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Glutathione Transferases and Polymorphisms as a percentage of every work published that year, 0.0072% in 2024.

still counting0.020%0.040%Glutathione Transferases and Polymorphisms0.0065% in 202519801990200020102020

Fractional works of Glutathione Transferases and Polymorphisms over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Glutathione Transferases and Polymorphisms10.4% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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