Topic · Gout, Hyperuricemia, Uric Acid
Most cited papers in Gout, Hyperuricemia, Uric Acid
What are the most cited papers in Gout, Hyperuricemia, Uric Acid?
The most cited paper in Gout, Hyperuricemia, Uric Acid is "Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017" (Boris T. Bikbov et al., 2020), with 6,840 citations. Next come "Gout-associated uric acid crystals activate the NALP3 inflammasome" (5,341) and "2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative" (5,002).
Showing 50 of 99 papers. Every paper with more than 822 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 Boris T. Bikbov et al. · The Lancet | Feb 2020 | 6,840 |
| 2 | Gout-associated uric acid crystals activate the NALP3 inflammasome Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature | 11 Jan 2006 | 5,341 |
| 3 | 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative Daniel Aletaha et al. · Annals of the Rheumatic Diseases | 10 Aug 2010 | 5,002 |
| 4 | Pyroptosis: host cell death and inflammation Tessa Bergsbaken, Susan L. Fink, Brad T. Cookson · Nature Reviews Microbiology | 16 Jan 2009 | 3,313 |
| 5 | Cryopyrin activates the inflammasome in response to toxins and ATP Sanjeev Mariathasan, David S. Weiss, Kim I. Newton et al. · Nature | 11 Jan 2006 | 3,104 |
| 6 | Mechanism and Regulation of NLRP3 Inflammasome Activation Yuan He, Hideki Hara, Gabriel Núñez · Trends in Biochemical Sciences | 24 Sep 2016 | 2,794 |
| 7 | Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion Wanting He, Haoqiang Wan, Lichen Hu et al. · Cell Research | 27 Nov 2015 | 2,580 |
| 8 | Uric Acid and Cardiovascular Risk Daniel I. Feig, Duk‐Hee Kang, Richard J. Johnson · New England Journal of Medicine | 22 Oct 2008 | 2,472 |
| 9 | Pyroptosis: mechanisms and diseases Pian Yu, Xu Zhang, Nian Liu et al. · Signal Transduction and Targeted Therapy | 28 Mar 2021 | 2,406 |
| 10 | Diagnosis and Management of Rheumatoid Arthritis Daniel Aletaha, Josef S Smolen · JAMA | 2 Oct 2018 | 2,381 |
| 11 | The European Spondylarthropathy Study Group Preliminary Criteria for the Classification of Spondylarthropathy Maxime Dougados, Sjef van der Linden, Roger Juhlin et al. · Arthritis & Rheumatism | 10 Oct 1991 | 2,299 |
| 12 | K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter Raúl Muñoz-Planillo, Peter Kuffa, Giovanny J. Martínez-Colón et al. · Immunity | Jun 2013 | 2,200 |
| 13 | Prevalence of gout and hyperuricemia in the US general population: The National Health and Nutrition Examination Survey 2007-2008 Yanyan Zhu, Bhavik J. Pandya, Hyon K. Choi · Arthritis & Rheumatism | 28 Jul 2011 | 1,824 |
| 14 | 2016 updated EULAR evidence-based recommendations for the management of gout Pascal Richette et al. · Annals of the Rheumatic Diseases | 25 Jul 2016 | 1,712 |
| 15 | Development and validation of the european league against rheumatism response criteria for rheumatoid arthritis: Comparison with the preliminary american college of rheumatology and the world health organization/international league against rheumatism criteria Anke M. van Gestel, M.L.L. Prevoo, Martin A. van't Hof et al. · Arthritis & Rheumatism | 1996 | 1,584 |
| 16 | NLRP3 inflammasome activation and cell death Yi Huang, Wen Rong Xu, Rongbin Zhou · Cellular and Molecular Immunology | 28 Jul 2021 | 1,583 |
| 17 | Molecular identification of a renal urate–anion exchanger that regulates blood urate levels Atsushi Enomoto, Hiroaki J. Kimura, Arthit Chairoungdua et al. · Nature | 14 Apr 2002 | 1,556 |
| 18 | 2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia Dinesh Khanna et al. · Arthritis Care & Research | 28 Sep 2012 | 1,542 |
| 19 | Serum Uric Acid and Cardiovascular Mortality Jing Fang, Michael H. Alderman · JAMA | 10 May 2000 | 1,524 |
| 20 | Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force Josef S Smolen et al. · Annals of the Rheumatic Diseases | 12 May 2015 | 1,484 |
| 21 | Risk of cardiovascular mortality in patients with rheumatoid arthritis: A meta‐analysis of observational studies Juan Antonio Aviña-Zubieta, Hyon K. Choi, Mohsen Sadatsafavi et al. · Arthritis Care & Research | 26 Nov 2008 | 1,473 |
| 22 | A familial disorder of uric acid metabolism and central nervous system function Michael Lesch, William L. Nyhan · The American Journal of Medicine | Apr 1964 | 1,468 |
| 23 | Preliminary criteria for the classification of the acute arthritis of primary gout Stanley L. Wallace, Harry Robinson, Alfonse T. Masi et al. · Arthritis & Rheumatism | Apr 1977 | 1,441 |
| 24 | EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee For International Clinical Studies Including Therapeutics (ESCISIT) Weiya Zhang, M Doherty, T Bardin et al. · Annals of the Rheumatic Diseases | 17 May 2006 | 1,420 |
| 25 | Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors Mats Dehlin, L. Jacobsson, Edward Roddy · Nature Reviews Rheumatology | 15 Jun 2020 | 1,409 |
| 26 | Regulation of uric acid metabolism and excretion Jessica Maiuolo, Francesca Oppedisano, Santo Gratteri et al. · International Journal of Cardiology | 14 Aug 2015 | 1,404 |
| 27 | Is There a Pathogenetic Role for Uric Acid in Hypertension and Cardiovascular and Renal Disease? Richard J. Johnson, Duk‐Hee Kang, Daniel I. Feig et al. · Hypertension | 21 Apr 2003 | 1,374 |
| 28 | Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout Michael A. Becker, H. Ralph Schumacher, Robert L. Wortmann et al. · New England Journal of Medicine | 7 Dec 2005 | 1,371 |
| 29 | Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells Zhiwei Zhou, Huabin He, Kun Wang et al. · Science | 16 Apr 2020 | 1,355 |
| 30 | High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors Inmaculada del Rincón, Ken M. Williams, Michael P. Stern et al. · Arthritis & Rheumatism | Dec 2001 | 1,352 |
| 31 | Gout Nicola Dalbeth, Anna L. Gosling, Angelo Gaffo et al. · The Lancet | 30 Mar 2021 | 1,346 |
| 32 | EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis M.J. Peters, Deborah P. M. Symmons, David W. McCarey et al. · Annals of the Rheumatic Diseases | 22 Sep 2009 | 1,325 |
| 33 | The mortality of rheumatoid arthritis Frederick Wolfe, Donald M. Mitchell, John T. Sibley et al. · Arthritis & Rheumatism | Dec 1994 | 1,323 |
| 34 | Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors Yang Yang, Huanan Wang, Mohammed Kouadir et al. · Cell Death and Disease | 12 Feb 2019 | 1,316 |
| 35 | A Role for Uric Acid in the Progression of Renal Disease Duk‐Hee Kang, Takahiko Nakagawa, Lili Feng et al. · Journal of the American Society of Nephrology | Dec 2002 | 1,312 |
| 36 | NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux Yuan He, Melody Yue Zeng, Dahai Yang et al. · Nature | 26 Jan 2016 | 1,311 |
| 37 | Elevated Uric Acid Increases Blood Pressure in the Rat by a Novel Crystal-Independent Mechanism Marilda Mazzali, Jeremy Hughes, Yoon-Goo Kim et al. · Hypertension | Nov 2001 | 1,303 |
| 38 | Serum Uric Acid and Risk for Cardiovascular Disease and Death: The Framingham Heart Study Bruce F. Culleton, Martin G. Larson, William B. Kannel et al. · Annals of Internal Medicine | 6 Jul 1999 | 1,303 |
| 39 | Antioxidant defenses and lipid peroxidation in human blood plasma. Balz Frei, Roland Stocker, B N Ames · Proceedings of the National Academy of Sciences | Dec 1988 | 1,259 |
| 40 | Cardiovascular Morbidity and Mortality in Women Diagnosed With Rheumatoid Arthritis Daniel H. Solomon, Elizabeth W. Karlson, Eric B. Rimm et al. · Circulation | 10 Mar 2003 | 1,254 |
| 41 | Frequency of infection in patients with rheumatoid arthritis compared with controls: A population‐based study Michele F. Doran, Cynthia S. Crowson, Gregory R. Pond et al. · Arthritis & Rheumatism | Sep 2002 | 1,235 |
| 42 | Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans Jennifer E. Huffman et al. · PLoS ONE | 26 Mar 2015 | 1,233 |
| 43 | Therapeutic Effects of Xanthine Oxidase Inhibitors: Renaissance Half a Century after the Discovery of Allopurinol Pál Pacher, Alex Nivorozhkin, Csaba Szabó · Pharmacological Reviews | 28 Feb 2006 | 1,219 |
| 44 | Hyperuricemia induces endothelial dysfunction Uday M. Khosla, Sergey I. Zharikov, Jennifer Finch et al. · Kidney International | 13 Apr 2005 | 1,212 |
| 45 | Global epidemiology of gout: prevalence, incidence and risk factors Chang‐Fu Kuo, Matthew J. Grainge, Weiya Zhang et al. · Nature Reviews Rheumatology | 7 Jul 2015 | 1,212 |
| 46 | Purine-Rich Foods, Dairy and Protein Intake, and the Risk of Gout in Men Hyon K. Choi, Karen A. Atkinson, Elizabeth W. Karlson et al. · New England Journal of Medicine | 10 Mar 2004 | 1,193 |
| 47 | Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins Alex J. MacGregor, Harold Snieder, Alan S. Rigby et al. · Arthritis & Rheumatism | 2000 | 1,189 |
| 48 | The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study Marita Cross, Emma U.R. Smith, Damian Hoy et al. · Annals of the Rheumatic Diseases | 19 Feb 2014 | 1,168 |
| 49 | Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 Thirumala‐Devi Kanneganti, Nesrin Özören, Mathilde Body–Malapel et al. · Nature | 11 Jan 2006 | 1,150 |
| 50 | FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation Jun Jacob Hu, Xing Liu, Shiyu Xia et al. · Nature Immunology | 4 May 2020 | 1,144 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.