Topic · Heat shock proteins research
Most cited papers in Heat shock proteins research
What are the most cited papers in Heat shock proteins research?
The most cited paper in Heat shock proteins research is "Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice" (Yi Chen, Lei Wang, Qiuxiang Kang et al., 2017), with 10,709 citations. Next come "The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation" (6,131) and "Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study" (5,057).
Showing 50 of 100 papers. Every paper with more than 1,106 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice Yi Chen, Lei Wang, Qiuxiang Kang et al. · Cellular Physiology and Biochemistry | 2017 | 10,709 |
| 2 | The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation Peter Walter, David Ron · Science | 24 Nov 2011 | 6,131 |
| 3 | Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study Hana Štorkánová, Sabína Oreská, Maja Špiritović et al. · Scientific Reports | 7 Jan 2021 | 5,057 |
| 4 | HEAT-SHOCK PROTEINS, MOLECULAR CHAPERONES, AND THE STRESS RESPONSE: Evolutionary and Ecological Physiology Martin E. Feder, Gretchen E. Hofmann · Annual Review of Physiology | Mar 1999 | 4,360 |
| 5 | Molecular chaperones in protein folding and proteostasis F. Ulrich Hartl, Andreas Bracher, Manajit K. Hayer-Hartl · Nature | Jul 2011 | 3,635 |
| 6 | Molecular chaperones in cellular protein folding F. Ulrich Hartl · Nature | Jun 1996 | 3,598 |
| 7 | Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein F. Ulrich Hartl, Manajit K. Hayer-Hartl · Science | 8 Mar 2002 | 3,390 |
| 8 | Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3 Hua Zou, William J. Henzel, Xuesong Liu et al. · Cell | Aug 1997 | 3,170 |
| 9 | Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1 Fumihiko Urano, Xiao-Zhong Wang, Anne Bertolotti et al. · Science | 28 Jan 2000 | 3,021 |
| 10 | The acute phase response Heinz Baumann, Jack Gauldie · Immunology Today | Feb 1994 | 2,922 |
| 11 | Hsp70 chaperones: Cellular functions and molecular mechanism Matthias P. Mayer, Bernd Bukau · Cellular and Molecular Life Sciences | Mar 2005 | 2,919 |
| 12 | Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response Anne Bertolotti, Yuhong Zhang, Linda M. Hendershot et al. · Nature Cell Biology | 8 May 2000 | 2,917 |
| 13 | Universal control mechanism regulating onset of M-phase Paul Nurse · Nature | Apr 1990 | 2,878 |
| 14 | The Hsp70 and Hsp60 Chaperone Machines Bernd Bukau, Arthur L. Horwich · Cell | Feb 1998 | 2,833 |
| 15 | Role of plant heat-shock proteins and molecular chaperones in the abiotic stress response Wang‐Xia Wang, Basia Vinocur, Oded Shoseyov et al. · Trends in Plant Science | 20 Mar 2004 | 2,803 |
| 16 | HSP90 and the chaperoning of cancer Luke J. Whitesell, Susan Lee Lindquist · Nature reviews. Cancer | 20 Sep 2005 | 2,514 |
| 17 | Macromolecular crowding: obvious but underappreciated R. John Ellis · Trends in Biochemical Sciences | Oct 2001 | 2,353 |
| 18 | Hsp90 as a capacitor for morphological evolution Suzanne L. Rutherford, Susan Lee Lindquist · Nature | Nov 1998 | 2,347 |
| 19 | THE FUNCTION OF HEAT-SHOCK PROTEINS IN STRESS TOLERANCE: DEGRADATION AND REACTIVATION OF DAMAGED PROTEINS Dawn A. Parsell, S Lindquist · Annual Review of Genetics | Dec 1993 | 2,228 |
| 20 | I-Mutant2.0: predicting stability changes upon mutation from the protein sequence or structure Emidio Capriotti, Piero Fariselli, Rita Casadio · Nucleic Acids Research | 26 Jun 2005 | 2,141 |
| 21 | The Heat Shock Response: Life on the Verge of Death Klaus Richter, Martin Haslbeck, Johannes Büchner · Molecular Cell | Oct 2010 | 2,111 |
| 22 | SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1 Ana Cuenda, James B. Rouse, Yair N. Doza et al. · FEBS Letters | 8 May 1995 | 2,100 |
| 23 | XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response Ann–Hwee Lee, Neal N. Iwakoshi, Laurie H. Glimcher · Molecular and Cellular Biology | 15 Oct 2003 | 2,099 |
| 24 | Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators Richard I. Morimoto · Genes & Development | 15 Dec 1998 | 1,938 |
| 25 | Heat Stroke Abderrezak Bouchama, James P. Knöchel · New England Journal of Medicine | 20 Jun 2002 | 1,887 |
| 26 | HSP90 at the hub of protein homeostasis: emerging mechanistic insights Mikko Taipale, Daniel F. Jarosz, Susan Lee Lindquist · Nature Reviews Molecular Cell Biology | 9 Jun 2010 | 1,872 |
| 27 | Alpha-crystallin can function as a molecular chaperone. Joseph Horwitz · Proceedings of the National Academy of Sciences | Nov 1992 | 1,847 |
| 28 | AAA+: A Class of Chaperone-Like ATPases Associated with the Assembly, Operation, and Disassembly of Protein Complexes Andrew F. Neuwald, L. Aravind, John L. Spouge et al. · Genome Research | 1999 | 1,847 |
| 29 | The HSP70 chaperone machinery: J proteins as drivers of functional specificity Harm H. Kampinga, Elizabeth Anne Craig · Nature Reviews Molecular Cell Biology | 23 Jul 2010 | 1,820 |
| 30 | The proteostasis network and its decline in ageing Mark S. Hipp, Prasad Kasturi, F. Ulrich Hartl · Nature Reviews Molecular Cell Biology | 7 Feb 2019 | 1,733 |
| 31 | The cellular and molecular basis of hyperthermia Bert Hildebrandt · Critical Reviews in Oncology/Hematology | Jul 2002 | 1,717 |
| 32 | Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones* William B. Pratt, David O. Toft · Endocrine Reviews | Jun 1997 | 1,702 |
| 33 | A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins John Wilson Rouse, Philip Cohen, Sylviane Trigon et al. · Cell | Sep 1994 | 1,681 |
| 34 | HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine Alexzander A. A. Asea, Stine‐Kathrein Kraeft, Evelyn A. Kurt‐Jones et al. · Nature Medicine | Apr 2000 | 1,620 |
| 35 | Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex Koji Ohashi, Volker Burkart, Stefanie B. Flohé et al. · The Journal of Immunology | 2000 | 1,614 |
| 36 | The HSP90 chaperone machinery Florian H. Schopf, Maximilian M. Biebl, Johannes Büchner · Nature Reviews Molecular Cell Biology | 21 Apr 2017 | 1,591 |
| 37 | Molecular Chaperones and Protein Quality Control Bernd Bukau, Jonathan S. Weissman, Arthur L. Horwich · Cell | May 2006 | 1,579 |
| 38 | Speculations on the functions of the major heat shock and glucose-regulated proteins Hugh R.B. Pelham · Cell | Sep 1986 | 1,570 |
| 39 | In vivo aspects of protein folding and quality control David Balchin, Manajit K. Hayer-Hartl, F. Ulrich Hartl · Science | 30 Jun 2016 | 1,546 |
| 40 | Targeting the dynamic HSP90 complex in cancer Jane B. Trepel, Mehdi Mollapour, Giuseppe Giaccone et al. · Nature reviews. Cancer | 23 Jul 2010 | 1,541 |
| 41 | Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor Ao‐Lin Hsu, Coleen Tara Murphy, Cynthia J. Kenyon · Science | 15 May 2003 | 1,539 |
| 42 | Molecular Chaperone Functions in Protein Folding and Proteostasis Yujin Kim, Mark S. Hipp, Andreas Bracher et al. · Annual Review of Biochemistry | 2 Jun 2013 | 1,519 |
| 43 | Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome Helen M. Beere, Beni B. Wolf, Kelvin Cain et al. · Nature Cell Biology | 4 Jul 2000 | 1,519 |
| 44 | Novel Signal Transduction Pathway Utilized by Extracellular HSP70 Alexzander A. A. Asea, Michael Rehli, Edith Kabingu et al. · Journal of Biological Chemistry | Apr 2002 | 1,510 |
| 45 | A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides Raymond J. Deshaies, B. Koch, Margaret Werner‐Washburne et al. · Nature | Apr 1988 | 1,505 |
| 46 | Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery William B. Pratt, David O. Toft · Experimental Biology and Medicine | Feb 2003 | 1,491 |
| 47 | Heat shock factors: integrators of cell stress, development and lifespan Malin Åkerfelt, Richard I. Morimoto, Lea Sistonen · Nature Reviews Molecular Cell Biology | 14 Jul 2010 | 1,490 |
| 48 | Recombinant protein expression in Escherichia coli François Baneyx · Current Opinion in Biotechnology | Oct 1999 | 1,489 |
| 49 | An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein Sean Munro, Hugh R.B. Pelham · Cell | Jul 1986 | 1,474 |
| 50 | Medical application of functionalized magnetic nanoparticles Akira Itô, Masashige Shinkai, Hiroyuki Honda et al. · Journal of Bioscience and Bioengineering | Jul 2005 | 1,469 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.