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Most cited papers in Hormonal Regulation and Hypertension

Hormonal Regulation and Hypertension

What are the most cited papers in Hormonal Regulation and Hypertension?

The most cited paper in Hormonal Regulation and Hypertension is "Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor" (Richard M. J. Palmer, Anthony G. Ferrige, Salvador Moncada, 1987), with 10,799 citations. Next come "The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure" (9,197) and "The Steroid and Thyroid Hormone Receptor Superfamily" (7,575).

Showing 50 of 98 papers. Every paper with more than 1,107 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor Richard M. J. Palmer, Anthony G. Ferrige, Salvador Moncada · Nature Jun 1987 10,799
2 The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure Bertram Pitt, Faiez M. Zannad, Willem J. Remme et al. · New England Journal of Medicine Open access 2 Sep 1999 9,197
3 The Steroid and Thyroid Hormone Receptor Superfamily Ronald M. Evans · Science Open access 13 May 1988 7,575
4 How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions* Robert Morris Sapolsky, L. Michael Romero, Allan U. Munck · Endocrine Reviews Feb 2000 6,620
5 Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol Björn Dahlöf, Richard B. Devereux, Sverre Erik Kjeldsen et al. · The Lancet Mar 2002 5,432
6 Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction Bertram Pitt, Willem J. Remme, Faiez M. Zannad et al. · New England Journal of Medicine Open access 2 Apr 2003 4,965
7 Stress and the brain: from adaptation to disease E. R. de Kloet, Marian Joëls, Florian Holsboer · Nature reviews. Neuroscience Review 13 May 2005 4,657
8 A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis Pere Puigserver, Zhidan Wu, Cheol Won Park et al. · Cell Open access Mar 1998 3,881
9 Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs Turk Rhen, John Anthony Cidlowski · New England Journal of Medicine 20 Oct 2005 3,178
10 The Protective Effects of Estrogen on the Cardiovascular System Michael E. Mendelsohn, Richard H. Karas · New England Journal of Medicine 10 Jun 1999 3,115
11 Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms Faiez M. Zannad, John J.V. McMurray, Henry Krum et al. · New England Journal of Medicine Open access 14 Nov 2010 3,112
12 Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions* Allan U. Munck, Paul M. Guyre, Nikki J. Holbrook · Endocrine Reviews 1984 3,104
13 Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension Jan A. Staessen, Robert H. Fagard, Lutgarde Thijs et al. · The Lancet Sep 1997 3,012
14 The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline John W. Funder, Robert M. Carey, Franco Mantero et al. · The Journal of Clinical Endocrinology & Metabolism Open access 2 Mar 2016 2,957
15 Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes George L. Bakris, Rajiv Agarwal, Stefan D. Anker et al. · New England Journal of Medicine Open access 23 Oct 2020 2,875
16 Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline Jacques W.M. Lenders, Quan‐Yang Duh, Graeme Eisenhofer et al. · The Journal of Clinical Endocrinology & Metabolism Open access Jun 2014 2,828
17 Spironolactone for Heart Failure with Preserved Ejection Fraction Bertram Pitt et al. · New England Journal of Medicine Open access 9 Apr 2014 2,808
18 The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation George Panagiotis Chrousos · New England Journal of Medicine 18 May 1995 2,611
19 Two Receptor Systems for Corticosterone in Rat Brain: Microdistribution and Differential Occupation Johannes M. H. M. Reul, E. R. de Kloet · Endocrinology Dec 1985 2,582
20 Brain Corticosteroid Receptor Balance in Health and Disease* E. R. de Kloet, Erno Vreugdenhil, Melly Silvana Oitzl et al. · Endocrine Reviews Open access Jun 1998 2,519
21 Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein Mark Stuart Anderson, Emily S. Venanzi, Ludger Klein et al. · Science 14 Nov 2002 2,499
22 The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders Walter L. Miller, Richard Joseph Auchus · Endocrine Reviews Open access Feb 2011 2,485
23 A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling Chetana M. Revankar, Daniel F. Cimino, Larry A. Sklar et al. · Science 10 Feb 2005 2,306
24 Neurocircuitry of stress: central control of the hypothalamo–pituitary–adrenocortical axis James P. Herman, William E. Cullinan · Trends in Neurosciences Review Feb 1997 2,291
25 Resistant Hypertension: Diagnosis, Evaluation, and Treatment David A. Calhoun, Daniel J Jones, Stephen C. Textor et al. · Circulation Open access 23 Jun 2008 2,241
26 The Corticosteroid Receptor Hypothesis of Depression Florian Holsboer · Neuropsychopharmacology Nov 2000 2,189
27 Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19 Muthiah Vaduganathan, Orly Vardeny, Thomas M. Michel et al. · New England Journal of Medicine Open access 30 Mar 2020 2,174
28 International Union of Pharmacology. XXIII. The Angiotensin II Receptors Marc de Gasparo, Kevin J. Catt, Tadashi Inagami et al. · Pharmacological Reviews Sep 2000 2,142
29 Calcitonin gene-related peptide is a potent vasodilator Susan Diana Brain, Tanya J. Williams, John R. Tippins et al. · Nature 1985 2,104
30 Benazepril plus Amlodipine or Hydrochlorothiazide for Hypertension in High-Risk Patients Kenneth Jamerson, Michael A. Weber, George L. Bakris et al. · New England Journal of Medicine Open access 3 Dec 2008 2,090
31 The HPA axis in major depression: classical theories and new developments Carmine Maria Pariante, Stafford Louis Lightman · Trends in Neurosciences Review Aug 2008 2,010
32 Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor Jeffrey L. Arriza, Cary Weinberger, Gail Cerelli et al. · Science 17 Jul 1987 1,973
33 Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction François Cambien, Odette Poirier, Laure Lecerf et al. · Nature 15 Oct 1992 1,937
34 Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system Puja K. Mehta, Kathy K. Griendling · American Journal of Physiology-Cell Physiology 27 Jul 2006 1,929
35 Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety François Tronche, Christoph Kellendonk, Oliver Kretz et al. · Nature Genetics Sep 1999 1,896
36 Stress and cognitive function Bruce S. McEwen, Robert Morris Sapolsky · Current Opinion in Neurobiology Review Apr 1995 1,894
37 Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension) Björn Dahlöf, L. Hansson, Lars Hjalmar Lindholm et al. · The Lancet Nov 1991 1,892
38 Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Dennis B. Lubahn, Jeffrey S. Moyer, THOMAS S. GOLDING et al. · Proceedings of the National Academy of Sciences Open access Dec 1993 1,861
39 Molecular basis of human hypertension: Role of angiotensinogen Xavier Jeunemaı̂tre, Florent Soubrier, Yuri V. Kotelevtsev et al. · Cell Oct 1992 1,861
40 Steroid hormone receptors: Many Actors in search of a plot Miguel Beato, Peter A. Herrlich, Günther Schütz · Cell Open access Dec 1995 1,851
41 1,25-Dihydroxyvitamin D3 is a negative endocrine regulator of the renin-angiotensin system Yan Chun Li, Juan Kong, Minjie Wei et al. · Journal of Clinical Investigation Open access 15 Jul 2002 1,832
42 ENDOCRINOLOGY OF THE STRESS RESPONSE Evangelia Charmandari, Constantine Tsigos, George Panagiotis Chrousos · Annual Review of Physiology Review Feb 2005 1,802
43 A Transgenic Model of Visceral Obesity and the Metabolic Syndrome Hiroaki Masuzaki, J. Paterson, Hiroshi Shinyama et al. · Science 7 Dec 2001 1,767
44 Overview of Steroidogenic Enzymes in the Pathway from Cholesterol to Active Steroid Hormones Anita H. Payne, Dale Buchanan Hales · Endocrine Reviews Dec 2004 1,765
45 Physiology of Local Renin-Angiotensin Systems Martin Paul, Ali Poyan Mehr, Reinhold Kreutz · Physiological Reviews Review 30 Jun 2006 1,747
46 Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction Tomasz Jan Guzik, Nyssa E. Hoch, Kathryn Brown et al. · The Journal of Experimental Medicine Open access 17 Sep 2007 1,744
47 Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes Bertram Pitt, Gerasimos Filippatos, Rajiv Agarwal et al. · New England Journal of Medicine Open access 28 Aug 2021 1,736
48 Molecular Mechanisms of Human Hypertension Richard P. Lifton, Ali G. Gharavi, David S. Geller · Cell Open access Feb 2001 1,705
49 Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones* William B. Pratt, David O. Toft · Endocrine Reviews Open access Jun 1997 1,702
50 Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor Kazuhiko Tatemoto, Masaki Hosoya, Yugo Habata et al. · Biochemical and Biophysical Research Communications Oct 1998 1,697

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.