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Most cited papers in IL-33, ST2, and ILC Pathways

What are the most cited papers in IL-33, ST2, and ILC Pathways?

The most cited paper in IL-33, ST2, and ILC Pathways is "Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death" (Jianjin Shi, Yue Zhao, Kun Wang et al., 2015), with 6,817 citations. Next come "The Inflammasomes" (5,489) and "The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells" (5,186).

Showing 50 of 100 papers. Every paper with more than 1,331 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature 16 Sep 2015 6,817
2 The Inflammasomes Kate Schroder, Jürg Tschopp · Cell Open access Mar 2010 5,489
3 The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell Open access Sep 2006 5,186
4 Unravelling the pathogenesis of inflammatory bowel disease Ramnik J. Xavier, Daniel K. Podolsky · Nature Jul 2007 4,394
5 Interleukin-10-deficient mice develop chronic enterocolitis Ralf Kühn, Jürgen Löhler, Donna M. Rennick et al. · Cell Oct 1993 4,325
6 Interaction between microbiota and immunity in health and disease Danping Zheng, Timur Liwinski, Eran Elinav · Cell Research Open access 20 May 2020 4,034
7 Multiple significance tests: the Bonferroni method Martin Bland, Doug G. Altman · BMJ Open access 21 Jan 1995 3,961
8 Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling Nobuhiko Kayagaki et al. · Nature 16 Sep 2015 3,790
9 IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines Jochen Schmitz, Alexander M. Owyang, Elizabeth R. Oldham et al. · Immunity Open access Nov 2005 3,763
10 The expanding universe of T-cell subsets: Th1, Th2 and more Tim R. Mosmann, Subash Sad · Immunology Today Mar 1996 3,673
11 A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment Susanne J. Szabo, Sean T. Kim, Gina L. Costa et al. · Cell Open access Mar 2000 3,615
12 Immunological and Inflammatory Functions of the Interleukin-1 Family Charles Anthony Dinarello · Annual Review of Immunology Review 20 Mar 2009 3,501
13 Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43 Kendle M. Maslowski, Angelica Thomas Vieira, Aylwin Ng et al. · Nature Open access Oct 2009 3,283
14 Intestinal epithelial cells: regulators of barrier function and immune homeostasis Lance W. Peterson, David Artis · Nature reviews. Immunology Review 25 Feb 2014 3,246
15 Sterile inflammation: sensing and reacting to damage Grace Chen, Gabriel Núñez · Nature reviews. Immunology ReviewOpen access 19 Nov 2010 3,052
16 A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene Richard H. Duerr et al. · Science Open access 26 Oct 2006 3,019
17 Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression Franz Georg Bauernfeind, Gabor L Horvath, Andrea Stutz et al. · The Journal of Immunology Open access Jul 2009 2,990
18 Regulatory T Cells: Mechanisms of Differentiation and Function Steven Zvi Josefowicz, Li‐Fan Lu, Alexander Yu Rudensky · Annual Review of Immunology ReviewOpen access 13 Jan 2007 2,898
19 A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases Rebecca C. Coll et al. · Nature Medicine Open access 16 Feb 2015 2,894
20 Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis Aurélien Trompette, Eva S. Gollwitzer, Koshika Yadava et al. · Nature Medicine Open access 5 Jan 2014 2,877
21 Mechanism and Regulation of NLRP3 Inflammasome Activation Yuan He, Hideki Hara, Gabriel Núñez · Trends in Biochemical Sciences ReviewOpen access 24 Sep 2016 2,794
22 Predominant TH2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma Douglas S. Robinson, Qutayba A. Hamid, Sun Ying et al. · New England Journal of Medicine 30 Jan 1992 2,772
23 Alternative Activation of Macrophages: An Immunologic Functional Perspective Fernando O. Martínez, Laura Helming, Siamon Gordon · Annual Review of Immunology Review 23 Dec 2008 2,768
24 Cytokines in inflammatory bowel disease Markus Friedrich Neurath · Nature reviews. Immunology Review 22 Apr 2014 2,704
25 The Effect of Infections on Susceptibility to Autoimmune and Allergic Diseases Jean‐François Bach · New England Journal of Medicine 18 Sep 2002 2,699
26 The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance Bolormaa Vandanmagsar, Yun‐Hee Youm, Anthony Ravussin et al. · Nature Medicine Open access 9 Jan 2011 2,648
27 Interleukin-13: Central Mediator of Allergic Asthma Marsha A. Wills-Karp, Jackie Luyimbazi, Xueying Xu et al. · Science 18 Dec 1998 2,648
28 Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease Jeffrey C. Barrett et al. · Nature Genetics Open access 29 Jun 2008 2,644
29 Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci André Franke et al. · Nature Genetics Open access 21 Nov 2010 2,592
30 Asthma phenotypes: the evolution from clinical to molecular approaches Sally E. Wenzel · Nature Medicine May 2012 2,446
31 Innate lymphoid cells — a proposal for uniform nomenclature Hergen Spits, David Artis, Marco Colonna et al. · Nature reviews. Immunology Review 7 Jan 2013 2,384
32 Interleukin-1 in the pathogenesis and treatment of inflammatory diseases Charles Anthony Dinarello · Blood Open access 8 Feb 2011 2,275
33 Inflammasomes in health and disease Till Strowig, Jorge Henao‐Mejia, Eran Elinav et al. · Nature 2012 2,261
34 Innate Lymphoid Cells: 10 Years On Eric D. Vivier, David Artis, Marco Colonna et al. · Cell Open access Aug 2018 2,174
35 NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines Christine A. Biron, Khuong B. Nguyen, Gary C. Pien et al. · Annual Review of Immunology Review Apr 1999 2,127
36 How colonization by microbiota in early life shapes the immune system Thomas Gensollen, Shankar S. Iyer, Dennis Lee Kasper et al. · Science Open access 28 Apr 2016 2,116
37 Eosinophilic esophagitis: Updated consensus recommendations for children and adults Chris Alexander Liacouras et al. · Journal of Allergy and Clinical Immunology Open access 9 Apr 2011 2,091
38 Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity Daniel R. Neill, See Heng Wong, Agustin Bellosi et al. · Nature Open access 3 Mar 2010 2,087
39 A Large-Scale, Consortium-Based Genomewide Association Study of Asthma Miriam F. Moffatt, Ivo Glynne Gut, Florence Démenais et al. · New England Journal of Medicine Open access 22 Sep 2010 2,069
40 The microbiome and innate immunity Christoph A. Thaiss, Niv Zmora, Maayan Levy et al. · Nature 5 Jul 2016 2,066
41 The inhibitory cytokine IL-35 contributes to regulatory T-cell function Lauren W. Collison, Creg J. Workman, Timothy T. Kuo et al. · Nature Nov 2007 2,056
42 Cluster Analysis and Clinical Asthma Phenotypes Pranabashis Haldar, Ian Douglas Pavord, Dominick E. Shaw et al. · American Journal of Respiratory and Critical Care Medicine Open access 14 May 2008 2,022
43 Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells Kazuyo Moro, Taketo Yamada, M. Tanabe et al. · Nature 20 Dec 2009 2,003
44 Cytokines in Inflammatory Disease Shinwan Kany, Jan Tilmann Vollrath, Borna Relja · International Journal of Molecular Sciences Open access 28 Nov 2019 2,000
45 Human Epicardial Adipose Tissue Is a Source of Inflammatory Mediators Tomasz Mazurek, Lifeng Zhang, Andrew A. Zalewski et al. · Circulation Open access 28 Oct 2003 1,990
46 The Interleukin-1 Family: Back to the Future Cecília Garlanda, Charles Anthony Dinarello, Alberto Mantovani · Immunity Open access Dec 2013 1,970
47 Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease Wenjun Ouyang, Sascha Rutz, Natasha K. Crellin et al. · Annual Review of Immunology Review Mar 2011 1,961
48 Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 Evanna L. Mills et al. · Nature Open access 27 Mar 2018 1,933
49 Targeting the NLRP3 inflammasome in inflammatory diseases Matthew Mangan, Edward J. Olhava, William R. Roush et al. · Nature Reviews Drug Discovery Review 20 Jul 2018 1,929
50 Overview of the IL ‐1 family in innate inflammation and acquired immunity Charles Anthony Dinarello · Immunological Reviews ReviewOpen access 16 Dec 2017 1,915

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.