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Topic · Immunology

IL-33, ST2, and ILC Pathways

IL-33, ST2, and ILC Pathways is a research topic within Immunology. Science Explorer counts 17k research works in it since 1954. 25.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the role of innate lymphoid cells, particularly their interaction with IL-33, in regulating type 2 immunity, tissue homeostasis, mucosal immunity, allergic inflammation, and the interplay with the adaptive immune system. It also delves into their involvement in various inflammatory diseases and their influence on regulatory T cells.

  • Innate Lymphoid Cells
  • IL-33
  • Type 2 Immunity
  • Tissue Homeostasis
  • Interleukin-1 Family
  • Mucosal Immunity
  • Allergic Inflammation
  • Regulatory T Cells
  • Adaptive Immune System
  • Inflammatory Diseases
Research works
17k
fractional, since 1954
In the world top 10%
4.3k
per year above
Top-10% rate
25.8%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+33%
the tick is no change

Which countries lead IL-33, ST2, and ILC Pathways research?

By volume, China and the United States publish the most (1.1k and 923 works in 2022–2025).

By volume, 2022–2025

  1. 1 China 1.1k works
  2. 2 United States 923 works
  3. 3 Japan 192 works
  4. 4 Germany 182 works
  5. 5 United Kingdom 171 works
  6. 6 Italy 133 works
  7. 7 France 113 works
  8. 8 South Korea 111 works
  9. 9 Canada 94 works
  10. 10 Spain 91 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 36.3%United States: 29.2%Japan: 6.1%Germany: 5.8%6 others listed: 22.6%36%largest
China1,147 · 36.3%United States923 · 29.2%Japan192 · 6.1%Germany182 · 5.8%6 others listed713 · 22.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead IL-33, ST2, and ILC Pathways research?

By volume in 2022–2025, Harvard University publishes the most IL-33, ST2, and ILC Pathways research, followed by Washington University in St. Louis and Nanjing Medical University.

Who are the leading researchers in IL-33, ST2, and ILC Pathways?

The most-cited researchers publishing on IL-33, ST2, and ILC Pathways include Shizuo Akira, Veikko Salomaa and Peter R. Galle.

  1. 1 Shizuo Akira Japan 3.6k citations
  2. 2 Veikko Salomaa Finland 3.3k citations
  3. 3 Peter R. Galle Germany 3.3k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is IL-33, ST2, and ILC Pathways research done?

The largest centres of IL-33, ST2, and ILC Pathways research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Seoul (South Korea). Among places with at least 20 works in it, it is an unusually large share of all research in Denver and Bethesda.

Largest cities, 2022–2025

  1. 1 Beijing China 137 works
  2. 2 Shanghai China 104 works
  3. 3 Guangzhou China 98 works
  4. 4 Seoul South Korea 58 works
  5. 5 Wuhan China 57 works
  6. 6 Paris France 55 works
  7. 7 London United Kingdom 55 works
  8. 8 Nanjing China 51 works
  9. 9 Tokyo Japan 51 works
  10. 10 Hangzhou China 47 works

Where it is the local speciality

  1. DenverUS · 20.2 works7.9×
  2. BethesdaUS · 30.0 works6.2×
← less than its size predictsmore →

Location quotient: how much more of its research is in IL-33, ST2, and ILC Pathways than the world average.

See IL-33, ST2, and ILC Pathways on the map

Where is the best place to study IL-33, ST2, and ILC Pathways?

Among universities, judged by research, Nanjing Medical University, Washington University in St. Louis and Harvard University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 30.47%fractional works in this node (log) →share in the world top 10% →Nanjing Medical University: 18, 24.9%Washington University in St. Louis: 18, 30.9%Harvard University: 18, 42.8%Guangzhou Medical University: 11, 21.3%Southern Medical University: 12, 34.6%University of Southern California: 12, 37.9%Chinese Academy of Medical Sciences & Peking Union Medical College: 17, 28.6%China Medical University: 12, 21.5%Cornell University: 11, 38.6%University of Colorado Denver: 12, 23.6%Harvard UniversityWashington Universit…Nanjing Medical Univ…Guangzhou Medical Un…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Nanjing Medical UniversityChina 66.324.9%9.1×18 +110.5%
2 Washington University in St. LouisUnited States 64.730.9%6.6×18 +105.1%
3 Harvard UniversityUnited States 63.142.8%3.7×18 +16.0%
4 Guangzhou Medical UniversityChina 60.821.3%10.7×11 +185.5%
5 Southern Medical UniversityChina 60.734.6%8.8×12 +69.8%
6 University of Southern CaliforniaUnited States 58.037.9%4.0×12 +198.6%
7 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 57.128.6%4.6×17 +129.1%
8 China Medical UniversityChina 55.521.5%9.8×12 +103.1%
9 Cornell UniversityUnited States 54.338.6%2.7×11 +234.4%
10 University of Colorado DenverUnited States 53.423.6%9.7×12 +36.1%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is IL-33, ST2, and ILC Pathways research growing?

Output in 2018–2022 was 33% higher than in 2013–2017, peaking in 2022. The fastest-growing topics are IL-33, ST2, and ILC Pathways.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.