Science Explorer Back to mapMap
Discussion
Topic · Immunology

Psoriasis: Treatment and Pathogenesis

Psoriasis: Treatment and Pathogenesis is a research topic within Immunology. Science Explorer counts 28k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the reciprocal developmental pathways for the generation of pathogenic effector TH17 cells and regulatory T cells, particularly in the context of autoimmune inflammation, interleukin-23, psoriasis, and the role of cytokines such as TGF-ß. It also explores the differentiation, cytokine profile, and function of human interleukin 17–producing helper T cells.

  • IL-17
  • TH17 Cells
  • Interleukin-23
  • Autoimmune Inflammation
  • Psoriasis
  • TGF-ß
  • Regulatory T Cells
  • Inflammatory Cytokines
  • Pathogenic Effector Cells
  • Immune System
Research works
28k
fractional, since 1950
In the world top 10%
2.8k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+26%
the tick is no change
Largest producer
China
26% of the 10 largest, 2022-now
Psoriasis: Treatment and Pathogenesis

Which countries lead Psoriasis: Treatment and Pathogenesis research?

By volume, China and the United States publish the most (1.5k and 1.5k works in 2022-now).

By volume, 2022-now

  1. 1 China 1.5k works
  2. 2 United States 1.5k works
  3. 3 India 463 works
  4. 4 Italy 419 works
  5. 5 United Kingdom 399 works
  6. 6 Germany 385 works
  7. 7 Spain 308 works
  8. 8 Japan 287 works
  9. 9 France 244 works
  10. 10 Canada 242 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 26.0%United States: 25.9%India: 8.1%Italy: 7.3%6 others listed: 32.7%26%largest
China1,487 · 26.0%United States1,478 · 25.9%India463 · 8.1%Italy419 · 7.3%6 others listed1,867 · 32.7%

Shares of the rows listed above, not of the whole node.

Which institutions lead Psoriasis: Treatment and Pathogenesis research?

By volume in 2022-now, Harvard University publishes the most Psoriasis: Treatment and Pathogenesis research, followed by Mount Sinai Health System and University of Toronto.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 66 works
  2. 2 Mount Sinai Health SystemUnited States 56 works
  3. 3 University of TorontoCanada 51 works
  4. 4 Central South UniversityChina 51 works
  5. 5 University of CopenhagenDenmark 45 works
  6. 6 Johnson & Johnson (United States)United States 42 works
  7. 7 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 41 works
  8. 8 Zhejiang UniversityChina 40 works
  9. 9 Universität HamburgGermany 36 works
  10. 10 InsermFrance 36 works

Who are the leading researchers in Psoriasis: Treatment and Pathogenesis?

The most-cited researchers publishing on Psoriasis: Treatment and Pathogenesis include Shizuo Akira, Cyrus Cooper and Jun Wang.

  1. 1 Shizuo Akira Japan 342k citations
  2. 2 Cyrus Cooper United Kingdom 342k citations
  3. 3 Jun Wang China 340k citations
  4. 4 Gordon Henry Guyatt Canada 315k citations
  5. 5 Gonçalo R. Abecasis United States 300k citations
  6. 6 Luigi Ferrucci United States 281k citations
  7. 7 Frank B. Hu United States 281k citations
  8. 8 Michael Karin United States 276k citations
  9. 9 Patrick M. Bossuyt Netherlands 270k citations
  10. 10 Mark I. McCarthy United Kingdom 267k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Psoriasis: Treatment and Pathogenesis?

The most cited paper in Psoriasis: Treatment and Pathogenesis is "Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells" (Estelle Bettelli, Yijun Carrier, Wenda Gao et al., 2006), with 7,030 citations. Next come "Dermatology Life Quality Index (DLQI)-a simple practical measure for routine clinical use" (5,635) and "The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells" (5,186).

Most cited papers
#PaperReleasedCitations
1 Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature 30 Apr 2006 7,030
2 Dermatology Life Quality Index (DLQI)-a simple practical measure for routine clinical use Andrew Yule Finlay, Ghazala Khan · Clinical and Experimental Dermatology May 1994 5,635
3 The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell Open access Sep 2006 5,186
4 IL-17 and Th17 Cells Thomas Korn, Estelle Bettelli, Mohamed Oukka et al. · Annual Review of Immunology Review 8 Jan 2009 4,889
5 Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan et al. · Nature Immunology 2 Oct 2005 4,759
All 100 most cited papers, with filters and sorting

Where is Psoriasis: Treatment and Pathogenesis research done?

The largest centres of Psoriasis: Treatment and Pathogenesis research in 2022-now are Beijing (China), Shanghai (China), New York (United States) and London (United Kingdom). Among places with at least 20 works in it, it is an unusually large share of all research in North Chicago.

Largest cities, 2022-now

  1. 1 BeijingChina 201 works
  2. 2 ShanghaiChina 157 works
  3. 3 New YorkUnited States 133 works
  4. 4 LondonUnited Kingdom 118 works
  5. 5 GuangzhouChina 107 works
  6. 6 SeoulSouth Korea 100 works
  7. 7 TokyoJapan 90 works
  8. 8 ParisFrance 88 works
  9. 9 RomeItaly 83 works
  10. 10 MoscowRussia 80 works

Where it is the local speciality

  1. North ChicagoUS · 21.3 works29×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Psoriasis: Treatment and Pathogenesis than the world average.

See Psoriasis: Treatment and Pathogenesis on the map

Where is the best place to study Psoriasis: Treatment and Pathogenesis?

Among universities, judged by research, University of Naples Federico II, Harvard University and Humanitas University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 17.53%fractional works in this field (log) →share of work in the world top 10% →University of Naples…Humanitas UniversityHarvard UniversityUniversity of Copenh…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1University of Naples Federico IIItaly 79.728.8%6.4×34 +60.3%
2Harvard UniversityUnited States 77.616.7%2.8×66 +14.3%
3Humanitas UniversityItaly 72.420.4%19.2×20 +164.1%
4University of CopenhagenDenmark 69.512.1%6.5×45 +25.6%
5Nippon Medical SchoolJapan 68.125.9%23.7×14 +188.2%
6University of TorontoCanada 67.411.6%3.4×51 +25.4%
7Central South UniversityChina 67.116.1%3.6×51 +100.3%
8King's College LondonUnited Kingdom 63.913.0%5.1×32 +95.4%
9University of LübeckGermany 62.118.6%17.9×19 +28.7%
10Karolinska InstitutetSweden 61.512.1%5.2×21 +19.1%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Psoriasis: Treatment and Pathogenesis, country by country

Is Psoriasis: Treatment and Pathogenesis research growing?

Output in 2022-2025 was 26% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Psoriasis: Treatment and Pathogenesis.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Psoriasis: Treatment and Pathogenesis as a percentage of every work published that year, 0.033% in 2024.

still counting0.020%0.040%Psoriasis: Treatment and Pathogenesis0.037% in 202519801990200020102020

Fractional works of Psoriasis: Treatment and Pathogenesis over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Psoriasis: Treatment and Pathogenesis9.9% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Questions people ask

Who is researching a cure for psoriasis?

By volume in 2022-now, Harvard University publishes the most Psoriasis: Treatment and Pathogenesis research, followed by Mount Sinai Health System and University of Toronto. By volume, China and the United States publish the most (1.5k and 1.5k works in 2022-now).

How much research is there on psoriasis, and is it growing?

Output in 2022-2025 was 26% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Psoriasis: Treatment and Pathogenesis.

Is Psoriasis: Treatment and Pathogenesis research growing?
All 1,273 questions in the Question Catalogue

Discussion

Ask a question or share a note about Psoriasis: Treatment and Pathogenesis. Posts are plain text and can be reported.