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Topic · Immunology

Reproductive System and Pregnancy

Reproductive System and Pregnancy is a research topic within Immunology. Science Explorer counts 49k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the immunological mechanisms involved in pregnancy, focusing on the interactions at the fetal-maternal interface, including the roles of decidual NK cells, regulatory T cells, HLA-G, and the Th1/Th2 paradigm. It delves into topics such as implantation, recurrent pregnancy loss, maternal-fetal tolerance, and endometrial receptivity.

  • Decidual NK Cells
  • Regulatory T Cells
  • Fetal-Maternal Interface
  • Implantation
  • Recurrent Pregnancy Loss
  • Maternal-Fetal Tolerance
  • HLA-G
  • Th1/Th2 Paradigm
  • Endometrial Receptivity
  • Immune Regulation
Research works
49k
fractional, since 1950
In the world top 10%
4.9k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+16%
the tick is no change
Largest producer
China
41% of the 10 largest, 2022-now

Which countries lead Reproductive System and Pregnancy research?

By volume, China and the United States publish the most (2.6k and 1.5k works in 2022-now).

By volume, 2022-now

  1. 1 China 2.6k works
  2. 2 United States 1.5k works
  3. 3 India 383 works
  4. 4 Russia 298 works
  5. 5 Japan 295 works
  6. 6 United Kingdom 278 works
  7. 7 Iran 270 works
  8. 8 Germany 257 works
  9. 9 Türkiye 246 works
  10. 10 Italy 223 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 41.1%United States: 23.1%India: 6.1%Russia: 4.7%6 others listed: 24.9%41%largest
China2,590 · 41.1%United States1,454 · 23.1%India383 · 6.1%Russia298 · 4.7%6 others listed1,570 · 24.9%

Shares of the rows listed above, not of the whole node.

Which institutions lead Reproductive System and Pregnancy research?

By volume in 2022-now, Russian Academy of Sciences publishes the most Reproductive System and Pregnancy research, followed by Harvard University and Shanghai Jiao Tong University.

Who are the leading researchers in Reproductive System and Pregnancy?

The most-cited researchers publishing on Reproductive System and Pregnancy include George Davey Smith, Mark J. Daly and Robert John Tibshirani.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Mark J. Daly United States 403k citations
  3. 3 Robert John Tibshirani United States 396k citations
  4. 4 Shizuo Akira Japan 342k citations
  5. 5 Jun Wang China 340k citations
  6. 6 Giuseppe Remuzzi Italy 328k citations
  7. 7 Gregory Y.H. Lip United Kingdom 311k citations
  8. 8 Dan J. Stein South Africa 306k citations
  9. 9 Róbert Langer United States 303k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Reproductive System and Pregnancy?

The most cited paper in Reproductive System and Pregnancy is "Sex differences in immune responses" (Sabra L. Klein, Katie L. Flanagan, 2016), with 6,634 citations. Next come "Inflammatory responses and inflammation-associated diseases in organs" (5,185) and "Macrophage biology in development, homeostasis and disease" (4,816).

Most cited papers
#PaperReleasedCitations
1 Sex differences in immune responses Sabra L. Klein, Katie L. Flanagan · Nature reviews. Immunology Review 22 Aug 2016 6,634
2 Inflammatory responses and inflammation-associated diseases in organs Linlin Chen, Huidan Deng, Hengmin Cui et al. · Oncotarget Open access 14 Dec 2017 5,185
3 Macrophage biology in development, homeostasis and disease Thomas A. Wynn, Ajay Chawla, Jeffrey W. Pollard · Nature Open access Apr 2013 4,816
4 Functional diversity of helper T lymphocytes Abul K. Abbas, KENNETH M. M. MURPHY, Alan Sher · Nature 31 Oct 1996 4,488
5 Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β George G. J. M. Kuiper, Bo Carlsson, Kaj Grandien et al. · Endocrinology Mar 1997 4,457
All 100 most cited papers, with filters and sorting

Where is Reproductive System and Pregnancy research done?

The largest centres of Reproductive System and Pregnancy research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Wuhan (China). Among places with at least 20 works in it, it is an unusually large share of all research in Pudong.

Largest cities, 2022-now

  1. 1 BeijingChina 247 works
  2. 2 ShanghaiChina 187 works
  3. 3 GuangzhouChina 184 works
  4. 4 WuhanChina 117 works
  5. 5 MoscowRussia 114 works
  6. 6 NanjingChina 112 works
  7. 7 HangzhouChina 111 works
  8. 8 TehranIran 103 works
  9. 9 LondonUnited Kingdom 99 works
  10. 10 JinanChina 91 works

Where it is the local speciality

  1. PudongCN · 26.6 works11×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Reproductive System and Pregnancy than the world average.

See Reproductive System and Pregnancy on the map

Where is the best place to study Reproductive System and Pregnancy?

Among universities, judged by research, Harvard University, Humanitas University and Karolinska Institutet score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 15.67%fractional works in this field (log) →share of work in the world top 10% →Humanitas UniversityZhejiang UniversityKarolinska InstitutetHarvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 69.010.8%2.8×69 +30.8%
2Humanitas UniversityItaly 66.132.3%7.6×9 +241.7%
3Karolinska InstitutetSweden 62.912.4%6.8×30 +44.9%
4Zhejiang UniversityChina 62.815.7%2.9×61 +39.6%
5Huazhong University of Science and TechnologyChina 61.419.6%3.2×46 +21.7%
6Peking UniversityChina 60.816.2%3.0×48 +40.1%
7Sun Yat-sen UniversityChina 58.611.6%3.4×55 +42.7%
8Sichuan UniversityChina 58.215.7%2.8×50 +45.2%
9Nanjing Medical UniversityChina 56.710.6%7.1×50 +25.0%
10Shanghai Jiao Tong UniversityChina 56.011.8%2.9×66 +1.7%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Reproductive System and Pregnancy, country by country

Is Reproductive System and Pregnancy research growing?

Output in 2022-2025 was 16% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Reproductive System and Pregnancy.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Reproductive System and Pregnancy as a percentage of every work published that year, 0.035% in 2024.

still counting0.025%0.050%0.075%Reproductive System and Pregnancy0.037% in 202519801990200020102020

Fractional works of Reproductive System and Pregnancy over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Reproductive System and Pregnancy9.9% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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