Most cited papers in Reproductive System and Pregnancy
What are the most cited papers in Reproductive System and Pregnancy?
The most cited paper in Reproductive System and Pregnancy is "Sex differences in immune responses" (Sabra L. Klein, Katie L. Flanagan, 2016), with 6,634 citations. Next come "Inflammatory responses and inflammation-associated diseases in organs" (5,185) and "Macrophage biology in development, homeostasis and disease" (4,816).
Showing 50 of 100 papers. Every paper with more than 1,220 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Sex differences in immune responses Sabra L. Klein, Katie L. Flanagan · Nature reviews. Immunology | 22 Aug 2016 | 6,634 |
| 2 | Inflammatory responses and inflammation-associated diseases in organs Linlin Chen, Huidan Deng, Hengmin Cui et al. · Oncotarget | 14 Dec 2017 | 5,185 |
| 3 | Macrophage biology in development, homeostasis and disease Thomas A. Wynn, Ajay Chawla, Jeffrey W. Pollard · Nature | Apr 2013 | 4,816 |
| 4 | Functional diversity of helper T lymphocytes Abul K. Abbas, KENNETH M. M. MURPHY, Alan Sher · Nature | 31 Oct 1996 | 4,488 |
| 5 | Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β George G. J. M. Kuiper, Bo Carlsson, Kaj Grandien et al. · Endocrinology | Mar 1997 | 4,457 |
| 6 | Nomenclature for Factors of the HLA System, 2026 Steven G.E. Marsh et al. · Tissue Antigens | 17 Mar 2010 | 4,206 |
| 7 | Functions of natural killer cells Eric D. Vivier, Elena Tomasello, Myriam Baratin et al. · Nature Immunology | 18 Apr 2008 | 3,951 |
| 8 | The expanding universe of T-cell subsets: Th1, Th2 and more Tim R. Mosmann, Subash Sad · Immunology Today | Mar 1996 | 3,673 |
| 9 | Endometriosis Linda C. Giudice, Lee C. Kao · The Lancet | Nov 2004 | 3,064 |
| 10 | The biology of human natural killer-cell subsets Megan A. Cooper, Todd A. Fehniger, Michael A. Caligiuri · Trends in Immunology | Nov 2001 | 2,980 |
| 11 | Innate or Adaptive Immunity? The Example of Natural Killer Cells Eric D. Vivier, David H. Raulet, Alessandro Moretta et al. · Science | 6 Jan 2011 | 2,809 |
| 12 | Systemic Lupus Erythematosus George C. Tsokos · New England Journal of Medicine | Dec 2011 | 2,774 |
| 13 | NK CELL RECOGNITION Lewis L. Lanier · Annual Review of Immunology | 11 Nov 2004 | 2,770 |
| 14 | Latest Advances in Understanding Preeclampsia Christopher W.G. Redman, Ian L. Sargent · Science | 9 Jun 2005 | 2,625 |
| 15 | Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism David H. Munn, Min Zhou, John T. Attwood et al. · Science | 21 Aug 1998 | 2,602 |
| 16 | Single-cell reconstruction of the early maternal–fetal interface in humans Roser Vento‐Tormo et al. · Nature | 8 Nov 2018 | 2,594 |
| 17 | Macrophage plasticity and polarization in tissue repair and remodelling Alberto Mantovani, Subhra Kumar Biswas, Maria Rosaria Galdiero et al. · The Journal of Pathology | 24 Oct 2012 | 2,422 |
| 18 | Ido expression by dendritic cells: tolerance and tryptophan catabolism Andrew L. Mellor, David H. Munn · Nature reviews. Immunology | Oct 2004 | 2,348 |
| 19 | Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages Marco Orecchioni, Yanal Ghosheh, Akula Bala Pramod et al. · Frontiers in Immunology | 24 May 2019 | 2,138 |
| 20 | Preeclampsia Sarosh Rana, Elizabeth R. Lemoine, Joey P. Granger et al. · Circulation Research | 28 Mar 2019 | 2,103 |
| 21 | Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor Colin L. Stewart, Petr Kašpar, Lisa J. Brunet et al. · Nature | Sep 1992 | 2,050 |
| 22 | Preterm labor: One syndrome, many causes Roberto J. Romero, Sudhansu K. Dey, Susan J. Fisher · Science | 14 Aug 2014 | 2,036 |
| 23 | The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor Carlie de Vries, Jaime A. Escobedo, Hikaru Ueno et al. · Science | 21 Feb 1992 | 2,034 |
| 24 | Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us? John F. Couse, Kenneth Steven Korach · Endocrine Reviews | Jun 1999 | 1,975 |
| 25 | The Complex Role of Estrogens in Inflammation Rainer Hans Straub · Endocrine Reviews | Aug 2007 | 1,959 |
| 26 | Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. John P. Lydon, Francesco John DeMayo, Cindee R. Funk et al. · Genes & Development | 15 Sep 1995 | 1,914 |
| 27 | Monocytes and macrophages: developmental pathways and tissue homeostasis Florent Ginhoux, Steffen Jung · Nature reviews. Immunology | 23 May 2014 | 1,864 |
| 28 | Evolution of the immune system in humans from infancy to old age Anna Katharina Simon, Georg A. Holländer, Andrew James McMichael · Proceedings of the Royal Society B Biological Sciences | 22 Dec 2015 | 1,826 |
| 29 | 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor Richard A. Heyman, David J. Mangelsdorf, Jacqueline A. Dyck et al. · Cell | 1992 | 1,809 |
| 30 | Soluble Endoglin and Other Circulating Antiangiogenic Factors in Preeclampsia Richard J. Levine, Chun Sing Lam, Cong Qian et al. · New England Journal of Medicine | 6 Sep 2006 | 1,806 |
| 31 | Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia Harald Zeisler, Elisa Llurba, Frédéric Chantraine et al. · New England Journal of Medicine | 6 Jan 2016 | 1,794 |
| 32 | The immunological and genetic basis of inflammatory bowel disease Gerd Bouma, Warren Strober · Nature reviews. Immunology | Jul 2003 | 1,788 |
| 33 | The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6 Haruhiko Akiyama, Marie‐Christine Chaboissier, James F. Martin et al. · Genes & Development | Nov 2002 | 1,750 |
| 34 | Role of oxidative stress in female reproduction Ashok Kumar Agarwal, Sajal Gupta, Rakesh Kumar Sharma · Reproductive Biology and Endocrinology | 14 Jul 2005 | 1,746 |
| 35 | Generation and reproductive phenotypes of mice lacking estrogen receptor β John Henry Krege, Jeffrey B. Hodgin, John F. Couse et al. · Proceedings of the National Academy of Sciences | 22 Dec 1998 | 1,709 |
| 36 | Maternal age and fetal loss: population based register linkage study Anne‐Marie Nybo Andersen · BMJ | 24 Jun 2000 | 1,706 |
| 37 | Decidual NK cells regulate key developmental processes at the human fetal-maternal interface Jacob H. Hanna, Debra Goldman‐Wohl, Yaron Hamani et al. · Nature Medicine | 6 Aug 2006 | 1,694 |
| 38 | Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis Sha Mi, Xinhua Lee, Xiangping Li et al. · Nature | Feb 2000 | 1,686 |
| 39 | Growth differentiation factor-9 is required during early ovarian folliculogenesis Jinwen Dong, David F. Albertini, Katsuhiko Nishimori et al. · Nature | Oct 1996 | 1,683 |
| 40 | The Immune System Peter J. Delves, Ivan M. Roitt · New England Journal of Medicine | 6 Jul 2000 | 1,673 |
| 41 | Regulatory T cells mediate maternal tolerance to the fetus Varuna R. Aluvihare, Marinos Kallikourdis, Alexander G. Betz · Nature Immunology | Feb 2004 | 1,658 |
| 42 | The effects of oxidative stress on female reproduction: a review Ashok Kumar Agarwal, Anamar Aponte-Mellado, Beena J. Premkumar et al. · Reproductive Biology and Endocrinology | 2012 | 1,651 |
| 43 | Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6 Stephen E. P. Smith, Jennifer S.Y. Li, Krassimira A. Garbett et al. · Journal of Neuroscience | 3 Oct 2007 | 1,650 |
| 44 | Inhibition of T Cell Proliferation by Macrophage Tryptophan Catabolism David H. Munn, Ebrahim Shafizadeh, John T. Attwood et al. · The Journal of Experimental Medicine | 3 May 1999 | 1,634 |
| 45 | Adaptive immune features of natural killer cells Joseph Chai-Yuen Sun, Joshua N. Beilke, Lewis L. Lanier · Nature | 11 Jan 2009 | 1,629 |
| 46 | Mechanism of a Reaction in Vitro Associated with Delayed-Type Hypersensitivity Barry R. Bloom, Boyce P. Bennett · Science | Jul 1966 | 1,620 |
| 47 | Pathogenesis and pathophysiology of endometriosis Richard O. Burney, Linda C. Giudice · Fertility and Sterility | 20 Jul 2012 | 1,601 |
| 48 | Epidemiology of ovarian cancer: a review Reid Brett M., Reid Brett M., Permuth Jennifer B. et al. · Cancer Biology and Medicine | 2017 | 1,588 |
| 49 | Purification, Characterization, andin vitroDifferentiation of Cytotrophoblasts from Human Term Placentae* Harvey J. Kliman, John E. Nestler, EDUARDO SERMASI et al. · Endocrinology | Apr 1986 | 1,585 |
| 50 | Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease Joan E. Durbin, Renée Hackenmiller, M. Celeste Simon et al. · Cell | Feb 1996 | 1,585 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.