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Topic · Immunology

Invertebrate Immune Response Mechanisms

Invertebrate Immune Response Mechanisms is a research topic within Immunology. Science Explorer counts 21k research works in it since 1951. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the diverse aspects of invertebrate immunity, focusing on the immune response, host defense mechanisms, and the role of various immune cells and pathways in organisms such as Drosophila. It covers topics such as antimicrobial peptides, stem cell involvement in immunity, pathogen recognition, and the Toll pathway.

  • Invertebrate Immunity
  • Host Defense
  • Drosophila
  • Immune Response
  • Hemocytes
  • Toll Pathway
  • Antimicrobial Peptides
  • Stem Cells
  • Phagocytosis
  • Pathogen Recognition
Research works
21k
fractional, since 1951
In the world top 10%
2.1k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+12%
the tick is no change
Largest producer
China
49% of the 10 largest, 2022-now
Invertebrate Immune Response Mechanisms

Which countries lead Invertebrate Immune Response Mechanisms research?

By volume, China and the United States publish the most (1.7k and 647 works in 2022-now).

By volume, 2022-now

  1. 1 China 1.7k works
  2. 2 United States 647 works
  3. 3 India 276 works
  4. 4 Japan 158 works
  5. 5 United Kingdom 142 works
  6. 6 France 122 works
  7. 7 Brazil 114 works
  8. 8 Germany 113 works
  9. 9 South Korea 112 works
  10. 10 Thailand 90 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 49.3%United States: 18.5%India: 7.9%Japan: 4.5%6 others listed: 19.8%49%largest
China1,724 · 49.3%United States647 · 18.5%India276 · 7.9%Japan158 · 4.5%6 others listed693 · 19.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead Invertebrate Immune Response Mechanisms research?

By volume in 2022-now, Chinese Academy of Agricultural Sciences publishes the most Invertebrate Immune Response Mechanisms research, followed by Chinese Academy of Sciences and Ministry of Agriculture and Rural Affairs.

By volume, 2022-now

  1. 1 Chinese Academy of Agricultural SciencesChina 72 works
  2. 2 Chinese Academy of SciencesChina 70 works
  3. 3 Ministry of Agriculture and Rural AffairsChina 66 works
  4. 4 Chinese Academy of Fishery SciencesChina 61 works
  5. 5 Shanghai Ocean UniversityChina 57 works
  6. 6 Ningbo UniversityChina 55 works
  7. 7 Centre National de la Recherche ScientifiqueFrance 46 works
  8. 8 Qingdao National Laboratory for Marine Science and TechnologyChina 44 works
  9. 9 Guangdong Ocean UniversityChina 42 works
  10. 10 Indian Council of Agricultural ResearchIndia 41 works

Who are the leading researchers in Invertebrate Immune Response Mechanisms?

The most-cited researchers publishing on Invertebrate Immune Response Mechanisms include Eric S. Lander, Peer Bork and Steven L. Salzberg.

  1. 1 Eric S. Lander United States 524k citations
  2. 2 Peer Bork Germany 396k citations
  3. 3 Steven L. Salzberg United States 372k citations
  4. 4 Shizuo Akira Japan 342k citations
  5. 5 Jun Wang China 340k citations
  6. 6 Matthias Mann Germany 308k citations
  7. 7 Koichiro Tamura Japan 268k citations
  8. 8 Xiaogang Wang China 260k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Invertebrate Immune Response Mechanisms?

The most cited paper in Invertebrate Immune Response Mechanisms is "Antimicrobial peptides of multicellular organisms" (MICHAEL A. ZASLOFF, 2002), with 8,479 citations. Next come "A human homologue of the Drosophila Toll protein signals activation of adaptive immunity" (5,620) and "Genome sequence of the human malaria parasite Plasmodium falciparum" (4,520).

Most cited papers
#PaperReleasedCitations
1 Antimicrobial peptides of multicellular organisms MICHAEL A. ZASLOFF · Nature 2002 8,479
2 A human homologue of the Drosophila Toll protein signals activation of adaptive immunity Ruslan M. Medzhitov, Paula Preston‐Hurlburt, Charles A. Janeway · Nature 24 Jul 1997 5,620
3 Genome sequence of the human malaria parasite Plasmodium falciparum Malcolm J. Gardner et al. · Nature Open access Oct 2002 4,520
4 The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults Bruno Lemaître, Émmanuelle Nicolas, Lydia Michaut et al. · Cell Open access Sep 1996 4,045
5 Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila Ryan H. Moy, Sara R. Cherry · Journal of Innate Immunity Open access 2013 3,551
All 100 most cited papers, with filters and sorting

Where is Invertebrate Immune Response Mechanisms research done?

The largest centres of Invertebrate Immune Response Mechanisms research in 2022-now are Beijing (China), Qingdao (China), Guangzhou (China) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in Zhanjiang and Zhoushan.

Largest cities, 2022-now

  1. 1 BeijingChina 235 works
  2. 2 QingdaoChina 127 works
  3. 3 GuangzhouChina 120 works
  4. 4 ShanghaiChina 100 works
  5. 5 NanjingChina 69 works
  6. 6 NingboChina 67 works
  7. 7 WuhanChina 54 works
  8. 8 HangzhouChina 51 works
  9. 9 ParisFrance 50 works
  10. 10 ChongqingChina 49 works

Where it is the local speciality

  1. ZhanjiangCN · 45.5 works28×
  2. ZhoushanCN · 22.8 works25×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Invertebrate Immune Response Mechanisms than the world average.

See Invertebrate Immune Response Mechanisms on the map

Where is the best place to study Invertebrate Immune Response Mechanisms?

Among universities, judged by research, Johns Hopkins University, Shanghai Ocean University and Ningbo University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 12.71%fractional works in this field (log) →share of work in the world top 10% →Johns Hopkins Univer…Southwest UniversityShanghai Ocean Unive…Ningbo University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Johns Hopkins UniversityUnited States 66.724.6%2.4×15 +14.4%
2Shanghai Ocean UniversityChina 62.67.8%62.8×57 +35.5%
3Ningbo UniversityChina 61.27.8%22.7×55 +52.8%
4Southwest UniversityChina 60.515.0%17.8×39 +0.5%
5Huazhong Agricultural UniversityChina 58.813.1%18.3×25 +23.8%
6Ocean University of ChinaChina 57.610.1%17.5×35 +21.0%
7Cornell UniversityUnited States 57.518.5%2.5×13 +7.8%
8Guangdong Ocean UniversityChina 57.27.2%66.7×42 +57.8%
9Fujian Agriculture and Forestry UniversityChina 55.713.4%20.3×19 +79.5%
10South China Agricultural UniversityChina 52.29.6%16.8×23 +59.6%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Invertebrate Immune Response Mechanisms, country by country

Is Invertebrate Immune Response Mechanisms research growing?

Output in 2022-2025 was 12% higher than in 2018-2021, peaking in 2026. The fastest-growing topics are Invertebrate Immune Response Mechanisms.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Invertebrate Immune Response Mechanisms as a percentage of every work published that year, 0.013% in 2024.

still counting0.010%0.020%0.030%Invertebrate Immune Response Mechanisms0.020% in 202519801990200020102020

Fractional works of Invertebrate Immune Response Mechanisms over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Invertebrate Immune Response Mechanisms10.1% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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