Most cited papers in Psoriasis: Treatment and Pathogenesis
What are the most cited papers in Psoriasis: Treatment and Pathogenesis?
The most cited paper in Psoriasis: Treatment and Pathogenesis is "Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells" (Estelle Bettelli, Yijun Carrier, Wenda Gao et al., 2006), with 7,030 citations. Next come "Dermatology Life Quality Index (DLQI)-a simple practical measure for routine clinical use" (5,635) and "The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells" (5,186).
Showing 50 of 100 papers. Every paper with more than 1,131 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature | 30 Apr 2006 | 7,030 |
| 2 | Dermatology Life Quality Index (DLQI)-a simple practical measure for routine clinical use Andrew Yule Finlay, Ghazala Khan · Clinical and Experimental Dermatology | May 1994 | 5,635 |
| 3 | The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell | Sep 2006 | 5,186 |
| 4 | IL-17 and Th17 Cells Thomas Korn, Estelle Bettelli, Mohamed Oukka et al. · Annual Review of Immunology | 8 Jan 2009 | 4,889 |
| 5 | Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan et al. · Nature Immunology | 2 Oct 2005 | 4,759 |
| 6 | A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology | 2 Oct 2005 | 4,286 |
| 7 | IL-23 drives a pathogenic T cell population that induces autoimmune inflammation Claire L. Langrish, Yi Chen, Wendy M. Blumenschein et al. · The Journal of Experimental Medicine | 17 Jan 2005 | 4,112 |
| 8 | Classification criteria for psoriatic arthritis: Development of new criteria from a large international study William John Taylor, Dafna D. Gladman, Philip Helliwell et al. · Arthritis & Rheumatism | 26 Jul 2006 | 3,789 |
| 9 | Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker Peter P. Bradley, Dennis A. Priebat, Robert D. Christensen et al. · Journal of Investigative Dermatology | Mar 1982 | 3,644 |
| 10 | TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells Marc Veldhoen, Richard J. Hocking, Christopher J. Atkins et al. · Immunity | Feb 2006 | 3,605 |
| 11 | The validity and practicality of sun-reactive skin types I through VI Thomas B. Fitzpatrick · Archives of Dermatology | Jun 1988 | 3,197 |
| 12 | Transforming growth factor-β induces development of the TH17 lineage Paul R. Mangan, Laurie E. Harrington, Darrell B. O’Quinn et al. · Nature | 30 Apr 2006 | 3,074 |
| 13 | Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain Daniel J. Cua, Jonathan P. Sherlock, Yi Chen et al. · Nature | Feb 2003 | 2,926 |
| 14 | Psoriasis Frank Oliver Nestle, Daniel H. Kaplan, Jonathan Barker · New England Journal of Medicine | 29 Jul 2009 | 2,797 |
| 15 | Severe Psoriasis – Oral Therapy with a New Retinoid Tove Fredriksson, U. Pettersson · Dermatologica | 14 Oct 2009 | 2,758 |
| 16 | Global Epidemiology of Psoriasis: A Systematic Review of Incidence and Prevalence Rosa Parisi, Deborah P. M. Symmons, Christopher E.M. Griffiths et al. · Journal of Investigative Dermatology | 27 Sep 2012 | 2,625 |
| 17 | Psoriasis Wolf‐Henning Boehncke, Michael P. Schön · The Lancet | 26 May 2015 | 2,567 |
| 18 | IL-6 as a keystone cytokine in health and disease Christopher A. Hunter, Simon A. Jones · Nature Immunology | 21 Apr 2015 | 2,555 |
| 19 | Psoriasis Christopher E.M. Griffiths, April Wang Armstrong, Johann Eli Gudjonsson et al. · The Lancet | Apr 2021 | 2,387 |
| 20 | Interleukin-17 Family Members and Inflammation Jay K. Kolls, Anders Lindén · Immunity | Oct 2004 | 2,386 |
| 21 | Pathophysiology, Clinical Presentation, and Treatment of Psoriasis April Wang Armstrong, Charlotte Read · JAMA | 19 May 2020 | 2,342 |
| 22 | Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis Leslie van der Fits, Sabine Mourits, Jane S.A. Voerman et al. · The Journal of Immunology | 21 Apr 2009 | 2,199 |
| 23 | IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways Liang Zhou, Ivaylo I. Ivanov, Rosanne J. Spolski et al. · Nature Immunology | 20 Jun 2007 | 2,166 |
| 24 | Pathogenesis and clinical features of psoriasis Christopher E.M. Griffiths, Jonathan NWN Barker · The Lancet | Jul 2007 | 2,164 |
| 25 | Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis Eric Lawrence Simpson et al. · New England Journal of Medicine | Oct 2016 | 2,101 |
| 26 | Psoriasis Pathogenesis and Treatment Adriana Rendón, Knut Schäkel · International Journal of Molecular Sciences | 23 Mar 2019 | 2,090 |
| 27 | Development, cytokine profile and function of human interleukin 17–producing helper T cells Nicholas J. Wilson, Katia Boniface, Jason R. Chan et al. · Nature Immunology | 5 Aug 2007 | 2,043 |
| 28 | Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials Richard G B Langley, Boni Elizabeth Elewski, Mark Lebwohl et al. · New England Journal of Medicine | 9 Jul 2014 | 2,004 |
| 29 | Reciprocal T H 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid Daniel Mucida, Yunji Park, Gisen Kim et al. · Science | 14 Jun 2007 | 1,973 |
| 30 | Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease Wenjun Ouyang, Sascha Rutz, Natasha K. Crellin et al. · Annual Review of Immunology | Mar 2011 | 1,961 |
| 31 | Serum 25-Hydroxyvitamin D Levels and Risk of Multiple Sclerosis Kassandra L. Munger, Lynn I. Levin, Bruce W. Hollis et al. · JAMA | 19 Dec 2006 | 1,907 |
| 32 | Risk of Myocardial Infarction in Patients With Psoriasis Joel M. Gelfand, Andrea L. Neimann, Daniel B. Shin et al. · JAMA | 10 Oct 2006 | 1,907 |
| 33 | Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1) Craig L. Leonardi, Alexa B. Kimball, Kim Alexander Papp et al. · The Lancet | May 2008 | 1,876 |
| 34 | Phenotypic and functional features of human Th17 cells Francesco Annunziato, Lorenzo Cosmi, Veronica Santarlasci et al. · The Journal of Experimental Medicine | 16 Jul 2007 | 1,874 |
| 35 | TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function Liang Zhou, Jared E. Lopes, Mark M. W. Chong et al. · Nature | 26 Mar 2008 | 1,869 |
| 36 | Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis Yan Zheng, Dimitry M. Danilenko, Patricia A Valdez et al. · Nature | 24 Dec 2006 | 1,868 |
| 37 | Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17 Sudeepta Aggarwal, Nico Ghilardi, Ming-Hong Xie et al. · Journal of Biological Chemistry | 2003 | 1,860 |
| 38 | IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells Thomas Korn, Estelle Bettelli, Wenda Gao et al. · Nature | 20 Jun 2007 | 1,856 |
| 39 | IL-17 Family Cytokines and the Expanding Diversity of Effector T Cell Lineages Casey Todd Weaver, Robin D. Hatton, Paul R. Mangan et al. · Annual Review of Immunology | 13 Jan 2007 | 1,855 |
| 40 | Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cells Eva V. Acosta Rodríguez, Giorgio Napolitani, Antonio Lanzavecchia et al. · Nature Immunology | 5 Aug 2007 | 1,840 |
| 41 | Ankylosing spondylitis Jürgen Braun, Joachim Sieper · The Lancet | Apr 2007 | 1,824 |
| 42 | Pathogenesis and therapy of psoriasis Michelle Anne Lowes, Anne M. Bowcock, James G. Krueger · Nature | Feb 2007 | 1,786 |
| 43 | Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine Ivaylo I. Ivanov, Rosa de Llanos, Nicolas Manel et al. · Cell Host & Microbe | Oct 2008 | 1,782 |
| 44 | Multiple Sclerosis — The Plaque and Its Pathogenesis Elliot M. Frohman, Michael K. Racke, Cedric S. Raine · New England Journal of Medicine | Mar 2006 | 1,768 |
| 45 | Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation Hania Kébir, Katharina Kreymborg, Igal Ifergan et al. · Nature Medicine | 9 Sep 2007 | 1,766 |
| 46 | Increased expression of interleukin 17 in inflammatory bowel disease Sanae Fujino, A Andoh, S Bamba et al. · Gut | 11 Dec 2002 | 1,718 |
| 47 | The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation Wenjun Ouyang, Jay K. Kolls, Yan Zheng · Immunity | Apr 2008 | 1,698 |
| 48 | Influence of Season and Latitude on the Cutaneous Synthesis of Vitamin D 3 : Exposure to Winter Sunlight in Boston and Edmonton Will Not Promote Vitamin D 3 Synthesis in Human Skin* Ann R. Webb, Loren Kline, Michael F. Holick · The Journal of Clinical Endocrinology & Metabolism | Aug 1988 | 1,675 |
| 49 | Immunology of Psoriasis Michelle Anne Lowes, Mayte Suárez‐Fariñas, James G. Krueger · Annual Review of Immunology | 21 Mar 2014 | 1,669 |
| 50 | Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation Craig A. Murphy, Claire L. Langrish, Yi Chen et al. · The Journal of Experimental Medicine | 8 Dec 2003 | 1,665 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.