Most cited papers in Immune cells in cancer
What are the most cited papers in Immune cells in cancer?
The most cited paper in Immune cells in cancer is "Integrated analysis of multimodal single-cell data" (Yuhan Hao et al., 2021), with 16,879 citations. Next come "Inflammation and cancer" (15,251) and "Cancer-related inflammation" (11,477).
Showing 50 of 100 papers. Every paper with more than 2,452 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Integrated analysis of multimodal single-cell data Yuhan Hao et al. · Cell | 31 May 2021 | 16,879 |
| 2 | Inflammation and cancer Lisa M. Coussens, Zena Werb · Nature | Dec 2002 | 15,251 |
| 3 | Cancer-related inflammation Alberto Mantovani, Paola Allavena, Antonio Sica et al. · Nature | Jul 2008 | 11,477 |
| 4 | Immunity, Inflammation, and Cancer Sergei I. Grivennikov, Florian R. Greten, Michael Karin · Cell | Mar 2010 | 10,888 |
| 5 | Exploring the full spectrum of macrophage activation David M. Mosser, Justin P. Edwards · Nature reviews. Immunology | 25 Nov 2008 | 9,246 |
| 6 | Neurotoxic reactive astrocytes are induced by activated microglia Shane A. Liddelow et al. · Nature | 2017 | 8,364 |
| 7 | Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Dominique A. Bonnet, John Edgar Dick · Nature Medicine | Jul 1997 | 7,031 |
| 8 | Myeloid-derived suppressor cells as regulators of the immune system Dmitry I. Gabrilovich, Srinivas Nagaraj · Nature reviews. Immunology | 7 Feb 2009 | 6,796 |
| 9 | The chemokine system in diverse forms of macrophage activation and polarization Alberto Mantovani, Antonello Sica, Silvano Sozzani et al. · Trends in Immunology | 6 Nov 2004 | 6,595 |
| 10 | Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion Robert D. Schreiber, Lloyd J. Old, Mark John Smyth · Science | 24 Mar 2011 | 6,561 |
| 11 | Macrophage plasticity and polarization: in vivo veritas Antonio Sica, Alberto Mantovani · Journal of Clinical Investigation | Mar 2012 | 6,482 |
| 12 | Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines Peter J. Murray et al. · Immunity | Jul 2014 | 6,444 |
| 13 | Understanding the tumor immune microenvironment (TIME) for effective therapy Mikhail Binnewies, Edward W. Roberts, Kelly Kersten et al. · Nature Medicine | 20 Apr 2018 | 6,338 |
| 14 | Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen · Science | 14 Apr 2005 | 5,970 |
| 15 | A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease Hadas Keren‐Shaul, Amit Spinrad, Assaf Weiner et al. · Cell | Jun 2017 | 5,874 |
| 16 | TIMER2.0 for analysis of tumor-infiltrating immune cells Taiwen Li, Jingxin Fu, Zexian Zeng et al. · Nucleic Acids Research | 17 May 2020 | 5,803 |
| 17 | Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes Alberto Mantovani, Silvano Sozzani, Massimo Locati et al. · Trends in Immunology | 21 Oct 2002 | 5,595 |
| 18 | Neutrophil recruitment and function in health and inflammation Elżbieta Kołaczkowska, Paul Kubes · Nature reviews. Immunology | 25 Feb 2013 | 5,537 |
| 19 | Dictionary learning for integrative, multimodal and scalable single-cell analysis Yuhan Hao, Tim Stuart, Madeline H. Kowalski et al. · Nature Biotechnology | 25 May 2023 | 5,523 |
| 20 | Protective and pathogenic functions of macrophage subsets Peter J. Murray, Thomas A. Wynn · Nature reviews. Immunology | 14 Oct 2011 | 5,326 |
| 21 | The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression Jean‐Philippe Coppé, Pierre‐Yves Desprez, Ana Krtolica et al. · Annual Review of Pathology Mechanisms of Disease | 2010 | 5,314 |
| 22 | Macrophage Diversity Enhances Tumor Progression and Metastasis Bin‐Zhi Qian, Jeffrey W. Pollard · Cell | Apr 2010 | 5,286 |
| 23 | Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages Florent Ginhoux, Melanie Greter, Marylène Leboeuf et al. · Science | 21 Oct 2010 | 5,266 |
| 24 | Monocyte and macrophage heterogeneity Siamon Gordon, Philip R. Taylor · Nature reviews. Immunology | Dec 2005 | 5,210 |
| 25 | Macrophage plasticity, polarization, and function in health and disease Abbas Shapouri Moghaddam, Saeed Mohammadian Haftcheshmeh, Hossein Vazini et al. · Journal of Cellular Physiology | 10 Jan 2018 | 5,011 |
| 26 | Macrophage biology in development, homeostasis and disease Thomas A. Wynn, Ajay Chawla, Jeffrey W. Pollard · Nature | Apr 2013 | 4,816 |
| 27 | Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer Gabriela Bindea, Bernhard Mlecnik, Marie Tosolini et al. · Immunity | Oct 2013 | 4,813 |
| 28 | The M1 and M2 paradigm of macrophage activation: time for reassessment Fernando O. Martínez, Siamon Gordon · F1000Prime Reports | 28 Feb 2014 | 4,795 |
| 29 | A cell initiating human acute myeloid leukaemia after transplantation into SCID mice Tsvee Lapidot, Christian Sirard, Josef H. Vormoor et al. · Nature | Feb 1994 | 4,789 |
| 30 | Obesity induces a phenotypic switch in adipose tissue macrophage polarization Carey Nien-Kai Lumeng, Jennifer L. Bodzin, Alan R. Saltiel · Journal of Clinical Investigation | 2 Jan 2007 | 4,656 |
| 31 | STATs in cancer inflammation and immunity: a leading role for STAT3 Hua Yu, Drew M. Pardoll, Richard Jove · Nature reviews. Cancer | 23 Oct 2009 | 4,442 |
| 32 | Microglia: a sensor for pathological events in the CNS Georg W. Kreutzberg · Trends in Neurosciences | Aug 1996 | 4,410 |
| 33 | Synaptic Pruning by Microglia Is Necessary for Normal Brain Development Rosa Chiara Paolicelli, Giulia Bolasco, Francesca Pagani et al. · Science | 21 Jul 2011 | 4,383 |
| 34 | Metabolic regulation of gene expression by histone lactylation Di Zhang et al. · Nature | 23 Oct 2019 | 4,352 |
| 35 | Profiling Tumor Infiltrating Immune Cells with CIBERSORT Binbin Chen, Michael Siavash Khodadoust, Chih Long Liu et al. · Methods in molecular biology | 2018 | 4,265 |
| 36 | Alternative Activation of Macrophages: Mechanism and Functions Siamon Gordon, Fernando O. Martínez · Immunity | May 2010 | 4,251 |
| 37 | Succinate is an inflammatory signal that induces IL-1β through HIF-1α Gillian M. Tannahill et al. · Nature | 22 Mar 2013 | 4,197 |
| 38 | Tumour-associated macrophages as treatment targets in oncology Alberto Mantovani, Federica Marchesi, Alberto Malesci et al. · Nature Reviews Clinical Oncology | 24 Jan 2017 | 4,183 |
| 39 | Tumor-Associated Macrophages: From Mechanisms to Therapy Roy Noy, Jeffrey W. Pollard · Immunity | Jul 2014 | 4,165 |
| 40 | The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth Karin E. de Visser, Johanna A. Joyce · Cancer Cell | Mar 2023 | 4,002 |
| 41 | Monocyte Chemoattractant Protein-1 (MCP-1): An Overview Satish L. Deshmane, Sergey G. Kremlev, Shohreh Amini et al. · Journal of Interferon & Cytokine Research | 14 May 2009 | 3,980 |
| 42 | A framework for advancing our understanding of cancer-associated fibroblasts Erik A. Sahai et al. · Nature reviews. Cancer | 24 Jan 2020 | 3,962 |
| 43 | Inflammation and Cancer: Triggers, Mechanisms, and Consequences Florian R. Greten, Sergei I. Grivennikov · Immunity | Jul 2019 | 3,881 |
| 44 | Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm Subhra Kumar Biswas, Alberto Mantovani · Nature Immunology | 20 Sep 2010 | 3,880 |
| 45 | Microenvironmental regulation of metastasis Johanna A. Joyce, Jeffrey W. Pollard · Nature reviews. Cancer | 12 Mar 2008 | 3,730 |
| 46 | Microglia: active sensor and versatile effector cells in the normal and pathologic brain Uwe‐Karsten Hanisch, Helmut Kettenmann · Nature Neuroscience | 26 Oct 2007 | 3,726 |
| 47 | Host microbiota constantly control maturation and function of microglia in the CNS Daniel Erny, Anna Lena Hrabě de Angelis, Diego Adhemar Jaitin et al. · Nature Neuroscience | Jun 2015 | 3,611 |
| 48 | Coordinated regulation of myeloid cells by tumours Dmitry I. Gabrilovich, Suzanne Ostrand‐Rosenberg, Vincenzo Bronte · Nature reviews. Immunology | 22 Mar 2012 | 3,573 |
| 49 | The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation Mercedes Ricote, Andrew C. Li, Timothy Mark Willson et al. · Nature | 1998 | 3,545 |
| 50 | Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq Amit Zeisel, Ana B. Muñoz‐Manchado, Simone Codeluppi et al. · Science | 21 Feb 2015 | 3,520 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.