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Most cited papers in Immune cells in cancer

What are the most cited papers in Immune cells in cancer?

The most cited paper in Immune cells in cancer is "Integrated analysis of multimodal single-cell data" (Yuhan Hao et al., 2021), with 16,879 citations. Next come "Inflammation and cancer" (15,251) and "Cancer-related inflammation" (11,477).

Showing 50 of 100 papers. Every paper with more than 2,452 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Integrated analysis of multimodal single-cell data Yuhan Hao et al. · Cell Open access 31 May 2021 16,879
2 Inflammation and cancer Lisa M. Coussens, Zena Werb · Nature Open access Dec 2002 15,251
3 Cancer-related inflammation Alberto Mantovani, Paola Allavena, Antonio Sica et al. · Nature Open access Jul 2008 11,477
4 Immunity, Inflammation, and Cancer Sergei I. Grivennikov, Florian R. Greten, Michael Karin · Cell Open access Mar 2010 10,888
5 Exploring the full spectrum of macrophage activation David M. Mosser, Justin P. Edwards · Nature reviews. Immunology ReviewOpen access 25 Nov 2008 9,246
6 Neurotoxic reactive astrocytes are induced by activated microglia Shane A. Liddelow et al. · Nature Open access 2017 8,364
7 Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Dominique A. Bonnet, John Edgar Dick · Nature Medicine Jul 1997 7,031
8 Myeloid-derived suppressor cells as regulators of the immune system Dmitry I. Gabrilovich, Srinivas Nagaraj · Nature reviews. Immunology ReviewOpen access 7 Feb 2009 6,796
9 The chemokine system in diverse forms of macrophage activation and polarization Alberto Mantovani, Antonello Sica, Silvano Sozzani et al. · Trends in Immunology 6 Nov 2004 6,595
10 Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion Robert D. Schreiber, Lloyd J. Old, Mark John Smyth · Science 24 Mar 2011 6,561
11 Macrophage plasticity and polarization: in vivo veritas Antonio Sica, Alberto Mantovani · Journal of Clinical Investigation Open access Mar 2012 6,482
12 Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines Peter J. Murray et al. · Immunity Open access Jul 2014 6,444
13 Understanding the tumor immune microenvironment (TIME) for effective therapy Mikhail Binnewies, Edward W. Roberts, Kelly Kersten et al. · Nature Medicine Open access 20 Apr 2018 6,338
14 Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen · Science 14 Apr 2005 5,970
15 A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease Hadas Keren‐Shaul, Amit Spinrad, Assaf Weiner et al. · Cell Open access Jun 2017 5,874
16 TIMER2.0 for analysis of tumor-infiltrating immune cells Taiwen Li, Jingxin Fu, Zexian Zeng et al. · Nucleic Acids Research Open access 17 May 2020 5,803
17 Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes Alberto Mantovani, Silvano Sozzani, Massimo Locati et al. · Trends in Immunology 21 Oct 2002 5,595
18 Neutrophil recruitment and function in health and inflammation Elżbieta Kołaczkowska, Paul Kubes · Nature reviews. Immunology ReviewOpen access 25 Feb 2013 5,537
19 Dictionary learning for integrative, multimodal and scalable single-cell analysis Yuhan Hao, Tim Stuart, Madeline H. Kowalski et al. · Nature Biotechnology Open access 25 May 2023 5,523
20 Protective and pathogenic functions of macrophage subsets Peter J. Murray, Thomas A. Wynn · Nature reviews. Immunology ReviewOpen access 14 Oct 2011 5,326
21 The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression Jean‐Philippe Coppé, Pierre‐Yves Desprez, Ana Krtolica et al. · Annual Review of Pathology Mechanisms of Disease ReviewOpen access 2010 5,314
22 Macrophage Diversity Enhances Tumor Progression and Metastasis Bin‐Zhi Qian, Jeffrey W. Pollard · Cell Open access Apr 2010 5,286
23 Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages Florent Ginhoux, Melanie Greter, Marylène Leboeuf et al. · Science Open access 21 Oct 2010 5,266
24 Monocyte and macrophage heterogeneity Siamon Gordon, Philip R. Taylor · Nature reviews. Immunology Review Dec 2005 5,210
25 Macrophage plasticity, polarization, and function in health and disease Abbas Shapouri Moghaddam, Saeed Mohammadian Haftcheshmeh, Hossein Vazini et al. · Journal of Cellular Physiology Open access 10 Jan 2018 5,011
26 Macrophage biology in development, homeostasis and disease Thomas A. Wynn, Ajay Chawla, Jeffrey W. Pollard · Nature Open access Apr 2013 4,816
27 Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer Gabriela Bindea, Bernhard Mlecnik, Marie Tosolini et al. · Immunity Open access Oct 2013 4,813
28 The M1 and M2 paradigm of macrophage activation: time for reassessment Fernando O. Martínez, Siamon Gordon · F1000Prime Reports Open access 28 Feb 2014 4,795
29 A cell initiating human acute myeloid leukaemia after transplantation into SCID mice Tsvee Lapidot, Christian Sirard, Josef H. Vormoor et al. · Nature Feb 1994 4,789
30 Obesity induces a phenotypic switch in adipose tissue macrophage polarization Carey Nien-Kai Lumeng, Jennifer L. Bodzin, Alan R. Saltiel · Journal of Clinical Investigation Open access 2 Jan 2007 4,656
31 STATs in cancer inflammation and immunity: a leading role for STAT3 Hua Yu, Drew M. Pardoll, Richard Jove · Nature reviews. Cancer ReviewOpen access 23 Oct 2009 4,442
32 Microglia: a sensor for pathological events in the CNS Georg W. Kreutzberg · Trends in Neurosciences Review Aug 1996 4,410
33 Synaptic Pruning by Microglia Is Necessary for Normal Brain Development Rosa Chiara Paolicelli, Giulia Bolasco, Francesca Pagani et al. · Science 21 Jul 2011 4,383
34 Metabolic regulation of gene expression by histone lactylation Di Zhang et al. · Nature Open access 23 Oct 2019 4,352
35 Profiling Tumor Infiltrating Immune Cells with CIBERSORT Binbin Chen, Michael Siavash Khodadoust, Chih Long Liu et al. · Methods in molecular biology Book chapterOpen access 2018 4,265
36 Alternative Activation of Macrophages: Mechanism and Functions Siamon Gordon, Fernando O. Martínez · Immunity Open access May 2010 4,251
37 Succinate is an inflammatory signal that induces IL-1β through HIF-1α Gillian M. Tannahill et al. · Nature Open access 22 Mar 2013 4,197
38 Tumour-associated macrophages as treatment targets in oncology Alberto Mantovani, Federica Marchesi, Alberto Malesci et al. · Nature Reviews Clinical Oncology ReviewOpen access 24 Jan 2017 4,183
39 Tumor-Associated Macrophages: From Mechanisms to Therapy Roy Noy, Jeffrey W. Pollard · Immunity Open access Jul 2014 4,165
40 The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth Karin E. de Visser, Johanna A. Joyce · Cancer Cell Open access Mar 2023 4,002
41 Monocyte Chemoattractant Protein-1 (MCP-1): An Overview Satish L. Deshmane, Sergey G. Kremlev, Shohreh Amini et al. · Journal of Interferon & Cytokine Research Open access 14 May 2009 3,980
42 A framework for advancing our understanding of cancer-associated fibroblasts Erik A. Sahai et al. · Nature reviews. Cancer ReviewOpen access 24 Jan 2020 3,962
43 Inflammation and Cancer: Triggers, Mechanisms, and Consequences Florian R. Greten, Sergei I. Grivennikov · Immunity Open access Jul 2019 3,881
44 Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm Subhra Kumar Biswas, Alberto Mantovani · Nature Immunology 20 Sep 2010 3,880
45 Microenvironmental regulation of metastasis Johanna A. Joyce, Jeffrey W. Pollard · Nature reviews. Cancer ReviewOpen access 12 Mar 2008 3,730
46 Microglia: active sensor and versatile effector cells in the normal and pathologic brain Uwe‐Karsten Hanisch, Helmut Kettenmann · Nature Neuroscience 26 Oct 2007 3,726
47 Host microbiota constantly control maturation and function of microglia in the CNS Daniel Erny, Anna Lena Hrabě de Angelis, Diego Adhemar Jaitin et al. · Nature Neuroscience Open access Jun 2015 3,611
48 Coordinated regulation of myeloid cells by tumours Dmitry I. Gabrilovich, Suzanne Ostrand‐Rosenberg, Vincenzo Bronte · Nature reviews. Immunology ReviewOpen access 22 Mar 2012 3,573
49 The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation Mercedes Ricote, Andrew C. Li, Timothy Mark Willson et al. · Nature 1998 3,545
50 Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq Amit Zeisel, Ana B. Muñoz‐Manchado, Simone Codeluppi et al. · Science Open access 21 Feb 2015 3,520

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.